Experimental characterization of a novel ventilation system for multi-story buildings with continuous curtain walls

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Alessandro Fascetti ◽  
Alessandro Palladino
Keyword(s):  
Experimental Evidence ◽  
Ventilation System ◽  
Neutral Plane ◽  
Temperature Fields ◽  
The Novel ◽  
Theoretical Derivation ◽  
Content Type ◽  
Design Procedures ◽  
Frame Element ◽  
Full Scale Tests

PurposeThe purpose of this paper is to present the results of an experimental campaign conducted on a recently developed fire protection system (FPS), specifically designed for installation on continuous glass curtain walls systems typical of multi-story buildings.Design/methodology/approachThe authors will first present the theoretical derivation of the relevant parameters to characterize and predict the fire evolution and probability of flashover, according to existing codes and standards. Then, the results of two full-scale tests will be presented in terms of temperature fields, thermal gradients and position of the neutral plane.FindingsThe experimental evidence shows how the proposed system is able to dramatically reduce internal temperatures in the rooms interested by the fire, also allowing for safer evacuation procedures by increasing the height of the neutral plane.Originality/valueThe novel window frame element comprises an automatic doubly convergent aperture system that induces ventilation in the compartment by increasing internal convection in the rooms subject to the fire. This allows for an efficient dispersion of hot gases and fumes and a drastic improvement in safety for both the occupants and firefighting operators. The theoretical results are then compared to the experimental evidence to evaluate the performance of the proposed ventilation system in the context of existing standards and design procedures.

Responses of Arab teachers of Hebrew in Israel to an Israeli novel on Jewish-Arab relations

2019 ◽  
Vol 35 (2) ◽  
pp. 1-17
Author(s):  
Shai Rudin
Keyword(s):  
Boarding School ◽  
Educational Systems ◽  
The Novel ◽  
Content Type ◽  
Reading Experience ◽  
Political Views ◽  
Arab Students ◽  
Complex Integration ◽  
Education College ◽  
Arab Sector

Purpose This study aims to examine the responses and perceptions of Israeli Arab teachers toward multicultural and educational issues concerning Jewish–Arab relations. Design/methodology/approach This study is a qualitative research. The study included 44 novice Arab teachers, who teach Hebrew in the Arab sector and are currently studying toward their masters’ degree at a teacher education college in northern Israel. The teachers were asked to read the novel Nadia by Galila Ron Feder–Amit. Published in 1985, the novel describes the complex integration of Nadia, an Arab village girl, into a Jewish boarding school, and it is narrated in first person. After having read the novel, the teachers were requested to answer the writing task, which addressed the character of the protagonist, the issue of teaching the novel in the Jewish and Arabic educational systems and the anticipated responses of Jewish and Arab students to the novel. Findings Phenomenological analysis of the teachers’ responses found that the reading experience was complex and resulted in a variety of responses toward the protagonist. Some were based on identification and appreciation, while others on criticism and judgment of the heroine’s restraint vis-a-vis the racism that she was experiencing. However, most of the teachers demonstrated moral courage and thought that the novel should be taught, as they viewed it as a bridge leading to understanding between the two nations. The teachers anticipated conflicting responses of Jewish and Arab students to the novel, according to the students’ political views and values. Practical implications These findings indicate that the educational system should include political texts relating to the Jewish–Arab schism, especially texts that voice the Palestinian narrative. This view differs from the current situation in both sectors, whereby the tendency is to avoid political texts while ignoring the Palestinian narrative. Originality/value The study shows that the reading experience of a political novel affords various and often contrasting responses with the teachers facing the didactic challenges. The teachers who participated in the study anticipated complexity of the reading and teaching process, yet were not deterred by it, particularly in view of the novel’s messages – striving to understand the “other” and to bridge a discourse between the nations.

Malignant astrocytoma following radiotherapy of a craniopharyngioma

1978 ◽  
Vol 48 (4) ◽  
pp. 622-627 ◽  
Author(s):  
Richard L. Sogg ◽  
Sarah S. Donaldson ◽  
Craig H. Yorke
Keyword(s):  
Experimental Evidence ◽  
Temporal Lobe ◽  
Malignant Astrocytoma ◽  
Content Type ◽  
Suprasellar Region ◽  
The Right ◽  
Fine Print

✓ A 9-year-old schoolgirl received 6007 rads to the suprasellar region for craniopharyngioma. Five years later, a malignant astrocytoma developed in the right temporal lobe. We cite clinical and experimental evidence to support our suspicion that the glioma may have been induced by radiation.

scholarly journals Novel Tandem Biotransformation Process for the Biosynthesis of a Novel Compound, 4-(2,3,5,6-Tetramethylpyrazine-1)-4′-Demethylepipodophyllotoxin

2011 ◽  
Vol 77 (9) ◽  
pp. 3023-3034 ◽  
Author(s):  
Ya-Jie Tang ◽  
Wei Zhao ◽  
Hong-Mei Li
Keyword(s):  
Cell Line ◽  
Alternaria Alternata ◽  
Water Solubility ◽  
Tumor Cell Line ◽  
Gibberella Fujikuroi ◽  
Hydroxyl Group ◽  
Epithelial Cell Line ◽  
The Novel ◽  
Content Type ◽  
Biotransformation Process

ABSTRACTAccording to the structure of podophyllotoxin and its structure-function relationship, a novel tandem biotransformation process was developed for the directional modification of the podophyllotoxin structure to directionally synthesize a novel compound, 4-(2,3,5,6-tetramethylpyrazine-1)-4′-demethylepipodophyllotoxin (4-TMP-DMEP). In this novel tandem biotransformation process, the starting substrate of podophyllotoxin was biotransformed into 4′-demethylepipodophyllotoxin (product 1) with the demethylation of the methoxyl group at the 4′ position byGibberella fujikuroiSH-f13, which was screened out from Shennongjia prime forest humus soil (Hubei, China). 4′-Demethylepipodophyllotoxin (product 1) was then biotransformed into 4′-demethylpodophyllotoxone (product 2) with the oxidation of the hydroxyl group at the 4 position byAlternaria alternataS-f6, which was screened out from the gatheredDysosma versipellisplants in the Wuhan Botanical Garden, Chinese Academy of Sciences. Finally, 4′-demethylpodophyllotoxone (product 2) and ligustrazine were linked with a transamination reaction to synthesize the target product 4-TMP-DMEP (product 3) byAlternaria alternataS-f6. Compared with podophyllotoxin (i.e., a 50% effective concentration [EC50] of 529 μM), the EC50of 4-TMP-DMEP against the tumor cell line BGC-823 (i.e., 0.11 μM) was significantly reduced by 5,199 times. Simultaneously, the EC50of 4-TMP-DMEP against the normal human proximal tubular epithelial cell line HK-2 (i.e., 0.40 μM) was 66 times higher than that of podophyllotoxin (i.e., 0.006 μM). Furthermore, compared with podophyllotoxin (i.e., logP= 0.34), the water solubility of 4-TMP-DMEP (i.e., logP= 0.66) was significantly enhanced by 94%. For the first time, the novel compound 4-TMP-DMEP with superior antitumor activity was directionally synthesized from podophyllotoxin by the novel tandem biotransformation process developed in this work.

New benchmark solutions for transient natural convection in partially porous annuli

2016 ◽  
Vol 26 (3/4) ◽  
pp. 1187-1225 ◽  
Author(s):  
Nicola Massarotti ◽  
Michela Ciccolella ◽  
Gino Cortellessa ◽  
Alessandro Mauro
Keyword(s):  
Natural Convection ◽  
Free Convection ◽  
Transient Flow ◽  
Flow Behavior ◽  
Outer Radius ◽  
Temperature Fields ◽  
Content Type ◽  
Transient Natural Convection ◽  
Velocity And Temperature Fields ◽  
Benchmark Solutions

Purpose – The purpose of this paper is to focus on the numerical analysis of transient free convection heat transfer in partially porous cylindrical domains. The authors analyze the dependence of velocity and temperature fields on the geometry, by analyzing transient flow behavior for different values of cavity aspect ratio and radii ratio; both inner and outer radius are assumed variable in order to not change the difference ro-ri. Moreover, several Darcy numbers have been considered. Design/methodology/approach – A dual time-stepping procedure based on the transient artificial compressibility version of the characteristic-based split algorithm has been adopted in order to solve the transient equations of the generalized model for heat and fluid flow through porous media. The present model has been validated against experimental data available in the scientific literature for two different problems, steady-state free convection in a porous annulus and transient natural convection in a porous cylinder, showing an excellent agreement. Findings – For vertically divided half porous cavities, with Rayleigh numbers equal to 3.4×106 for the 4:1 cavity and 3.4×105 for the 8:1 cavity, the numerical results show that transient oscillations tend to disappear in presence of cylindrical geometry, differently from what happens for rectangular one. The magnitude of this phenomenon increases with radii ratio; the porous layer also affects the stability of velocity and temperature fields, as oscillations tend to decrease in presence of a porous matrix with lower value of the Darcy number. Research limitations/implications – A proper analysis of partially porous annular cavities is fundamental for the correct estimation of Nusselt numbers, as the formulas provided for rectangular domains are not able to describe these problems. Practical implications – The proposed model represents a useful tool for the study of transient natural convection problems in porous and partially porous cylindrical and annular cavities, typical of many engineering applications. Moreover, a fully explicit scheme reduces the computational costs and ensures flexibility. Originality/value – This is the first time that a fully explicit finite element scheme is employed for the solution of transient natural convection in partially porous tall annular cavities.

scholarly journals The Novel Arylamidine T-2307 MaintainsIn VitroandIn VivoActivity against Echinocandin-Resistant Candida albicans

2014 ◽  
Vol 59 (2) ◽  
pp. 1341-1343 ◽  
Author(s):  
Nathan P. Wiederhold ◽  
Laura K. Najvar ◽  
Annette W. Fothergill ◽  
Rosie Bocanegra ◽  
Marcos Olivo ◽  
...  
Keyword(s):  
Body Weight ◽  
Candida Albicans ◽  
Invasive Candidiasis ◽  
Placebo Control ◽  
The Novel ◽  
Content Type ◽  
Fungal Burden ◽  
Potential Use

ABSTRACTWe evaluated thein vitroandin vivoactivities of the investigational arylamidine T-2307 against echinocandin-resistantCandida albicans. T-2307 demonstrated potentin vitroactivity, and daily subcutaneous doses between 0.75 and 6 mg/kg of body weight significantly improved survival and reduced fungal burden compared to placebo control and caspofungin (10 mg/kg/day) in mice with invasive candidiasis caused by an echinocandin-resistant strain. Thus, T-2307 may have potential use in the treatment of echinocandin-resistantC. albicansinfections.

scholarly journals Burkholderia insulsa sp. nov., a facultatively chemolithotrophic bacterium isolated from an arsenic-rich shallow marine hydrothermal system

2015 ◽  
Vol 65 (Pt_1) ◽  
pp. 189-194 ◽  
Author(s):  
Antje Rusch ◽  
Shaer Islam ◽  
Pratixa Savalia ◽  
Jan P. Amend
Keyword(s):  
Type Species ◽  
Sequence Similarity ◽  
Rrna Gene ◽  
The Novel ◽  
Carbohydrate Utilization ◽  
Content Type ◽  
Link Type ◽  
Optimum Ph ◽  
Shallow Marine Hydrothermal System ◽  
Type Strains

Enrichment cultures inoculated with hydrothermally influenced nearshore sediment from Papua New Guinea led to the isolation of an arsenic-tolerant, acidophilic, facultatively aerobic bacterial strain designated PNG-AprilT. Cells of this strain were Gram-stain-negative, rod-shaped, motile and did not form spores. Strain PNG-AprilT grew at temperatures between 4 °C and 40 °C (optimum 30–37 °C), at pH 3.5 to 8.3 (optimum pH 5–6) and in the presence of up to 2.7 % NaCl (optimum 0–1.0 %). Both arsenate and arsenite were tolerated up to concentrations of at least 0.5 mM. Metabolism in strain PNG-AprilT was strictly respiratory. Heterotrophic growth occurred with O2 or nitrate as electron acceptors, and aerobic lithoautotrophic growth was observed with thiosulfate or nitrite as electron donors. The novel isolate was capable of N2-fixation. The respiratory quinones were Q-8 and Q-7. Phylogenetically, strain PNG-AprilT belongs to the genus Burkholderia and shares the highest 16S rRNA gene sequence similarity with the type strains of Burkholderia fungorum (99.8 %), Burkholderia phytofirmans (98.8 %), Burkholderia caledonica (98.4 %) and Burkholderia sediminicola (98.4 %). Differences from these related species in several physiological characteristics (lipid composition, carbohydrate utilization, enzyme profiles) and DNA–DNA hybridization suggested the isolate represents a novel species of the genus Burkholderia , for which we propose the name Burkholderia insulsa sp. nov. The type strain is PNG-AprilT ( = DSM 28142T = LMG 28183T).

A novel fractional discrete grey model with an adaptive structure and its application in electricity consumption prediction

Kybernetes ◽  
2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Yitong Liu ◽  
Yang Yang ◽  
Dingyu Xue ◽  
Feng Pan
Keyword(s):  
Fractional Order ◽  
Electricity Consumption ◽  
Grey Model ◽  
The Novel ◽  
Raw Data ◽  
Content Type ◽  
Power Load ◽  
Grey Models ◽  
Novel Model ◽  
Consumption Prediction

PurposeElectricity consumption prediction has been an important topic for its significant impact on electric policies. Due to various uncertain factors, the growth trends of electricity consumption in different cases are variable. However, the traditional grey model is based on a fixed structure which sometimes cannot match the trend of raw data. Consequently, the predictive accuracy is variable as cases change. To improve the model's adaptability and forecasting ability, a novel fractional discrete grey model with variable structure is proposed in this paper.Design/methodology/approachThe novel model can be regarded as a homogenous or non-homogenous exponent predicting model by changing the structure. And it selects the appropriate structure depending on the characteristics of raw data. The introduction of fractional accumulation enhances the predicting ability of the novel model. And the relative fractional order r is calculated by the numerical iterative algorithm which is simple but effective.FindingsTwo cases of power load and electricity consumption in Jiangsu and Fujian are applied to assess the predicting accuracy of the novel grey model. Four widely-used grey models, three classical statistical models and the multi-layer artificial neural network model are taken into comparison. The results demonstrate that the novel grey model performs well in all cases, and is superior to the comparative eight models.Originality/valueA fractional-order discrete grey model with an adaptable structure is proposed to solve the conflict between traditional grey models' fixed structures and variable development trends of raw data. In applications, the novel model has satisfied adaptability and predicting accuracy.

Survey on the dissemination of Web-based information on “evacuation and sheltering” in the context of COVID-19 by the Japanese Government

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Hiroaki Sano ◽  
Yohei Chiba ◽  
Sachiko Maeda ◽  
Chiharu Ikeda ◽  
Nobuyuki Handa ◽  
...  
Keyword(s):  
Design Methodology ◽  
Information Dissemination ◽  
Central Government ◽  
Health Centers ◽  
The Novel ◽  
Web Based ◽  
Content Type ◽  
Administrative Agencies ◽  
Novel Coronavirus ◽  
Actual Response

Purpose This study examines the websites of central government ministries, prefectures and municipalities to obtain a comprehensive bird’s-eye view of how they are preparing for natural disasters in the context of the novel coronavirus (COVID-19) outbreak. Design/methodology/approach This study examines the websites of central government ministries, prefectures and municipalities in Japan to survey the actual status of information dissemination on “evacuation and sheltering” in the context of COVID-19. Findings This study found that the central government issued many notices, notifications and administrative communications to prefectures, cities with public health centers and special wards, which were mainly related to opening, securing and operating evacuation centers and improving the environment. It was found that most prefectures disseminated information on both survival and living evacuation and did so from June onward, when the flood season was approaching. Among the municipalities, there were differences in information dissemination tendencies by prefecture, and it became clear that smaller municipalities were especially incapable of fully disseminating information via the Web. Research limitations/implications The data from the prefectures and municipalities surveyed in this study were collected from websites and do not necessarily represent the actual response to disaster-related evacuation in the context of COVID-19 in those areas. To clarify this evacuation, more detailed surveys are needed. Originality/value This study is unique because no research has been conducted on the response of Japanese administrative agencies to disaster-related evacuation in the context of COVID-19; the actual situation was analyzed in this study by examining central government ministries, prefectures and municipalities as administrative agencies and comparing their responses.

Volatility transmission across international markets amid COVID 19 pandemic

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Hechem Ajmi ◽  
Nadia Arfaoui ◽  
Karima Saci
Keyword(s):  
Crude Oil ◽  
International Markets ◽  
The Novel ◽  
Data Set ◽  
Health Crisis ◽  
Content Type ◽  
Volatility Transmission ◽  
Oil Markets ◽  
Novel Coronavirus ◽  
Death Cases

Purpose This paper aims to investigate the volatility transmission across stocks, gold and crude oil markets before and during the novel coronavirus (COVID-19) crisis. Design/methodology/approach A multivariate vector autoregression (VAR)-Baba, Engle, Kraft and Kroner generalized autoregressive conditional heteroskedasticity model (BEKK-GARCH) is used to assess volatility transmission across the examined markets. The sample is divided as follows. The first period ranging from 02/01/2019 to 10/03/2020 defines the pre-COVID-19 crisis. The second period is from 11/03/2020 to 05/10/2020, representing the COVID-19 crisis period. Then, a robustness test is used using exponential GARCH models after including an exogenous variable capturing the growth of COVID-19 confirmed death cases worldwide with the aim to test the accuracy of the VAR-BEKK-GARCH estimated results. Findings Results indicate that the interconnectedness among the examined market has been intensified during the COVID-19 crisis, proving the lack of hedging opportunities. It is also found that stocks and Gold markets lead the crude oil market especially during the COVID-19 crisis, which explains the freefall of the crude oil price during the health crisis. Similarly, results show that Gold is most likely to act as a diversifier rather than a hedging tool during the current health crisis. Originality/value Although the recent studies in the field focused on analyzing the relationships between different markets during the first quarter of 2020, this study considers a larger data set with the aim to assess the volatility transmission across the examined international markets Amid the COVID-19 crisis, while it shows the most significant impact on various financial markets compared to other diseases.

Place–brand stereotypes: does stereotype-consistent messaging matter?

2018 ◽  
Vol 27 (7) ◽  
pp. 754-767
Author(s):  
Brittney C. Bauer ◽  
Clark D. Johnson ◽  
Nitish Singh
Keyword(s):  
Mediating Effect ◽  
The Novel ◽  
Perceived Fit ◽  
Experimental Conditions ◽  
Content Type ◽  
Global Brands ◽  
Place Brand ◽  
Foreign Brands ◽  
Improve Attitude ◽  
Post Hoc

Purpose The purpose of this paper is to address an overarching question: Does matching consumer place–brand associations with stereotype-consistent messaging affect consumer perceptions of an advertisement? Design/methodology/approach This paper presents two experiments that examine participants’ differing evaluations of advertisements under various experimental conditions. Study 1 examines the match of place–brand warmth versus competence stereotypes and the use of symbolic versus utilitarian advertising messaging for both new foreign and domestic brands. Study 2 examines this match for global brands. Findings The paper reveals that stereotype-consistent messaging increases the perceived fit between the advertisement and the brand for new foreign brands but not for new domestic or global brands. Furthermore, in a post-hoc analysis, this congruence is found to improve attitude towards the brand, purchase intentions and brand response, through the mediating effect of attitude towards the ad. Originality/value Place–brand stereotypes impact consumer attitudes and opinions regarding brands from different countries. This paper applies two universal social judgment dimensions from social psychology—warmth and competence—to the novel context of advertising messaging to examine previously unexplored facets of the place–brand image.

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