Fabrication of nanocellulose/PEGDA hydrogel by 3D printing

2018 ◽  
Vol 24 (8) ◽  
pp. 1265-1271 ◽  
Author(s):  
Aimin Tang ◽  
Qinwen Wang ◽  
Shan Zhao ◽  
Wangyu Liu
Keyword(s):  
Additive Manufacturing ◽  
3D Printing ◽  
3D Structure ◽  
Three Dimensional ◽  
Aqueous Dispersion ◽  
Compression Modulus ◽  
Content Type ◽  
Precise Control ◽  
Light Curing ◽  
Equilibrium Swelling Ratio

Purpose Nanocellulose is characterised by favourable biocompatibility, degradability, nanostructure effect, high modulus and high tensile strength and has been widely applied in various fields. The current research in the field of new nanocellulose materials mainly focuses on the hydrogel, aerogel and the tissue engineering scaffold. All of these are three-dimensional (3D) porous materials, but conventional manufacturing technology fails to realise precise control. Therefore, the method of preparing structural materials using 3D printing and adopting the nanocellulose as the 3D printing material has been proposed. Then, how to realise 3D printing of nanocellulose is the problem that should be solved. Design/methodology/approach By adding the photosensitive component polyethyleneglycol diacrylate (PEGDA) in the aqueous dispersion system of nanocellulose, the nanocellulose was endowed with photosensitivity. Then, nanocellulose/PEGDA hydrogels were prepared by the additive manufacturing of nanocellulose through light curing. Findings The results showed that the nanocellulose/PEGDA hydrogels had a uniform shape and a controllable structure. The nanocellulose supported the scaffold structure in the hydrogels. Prepared with 1.8 per cent nanocellulose through 40 s of light curing, the nanocellulose/PEGDA hydrogels had a maximum compression modulus of 0.91 MPa. The equilibrium swelling ratio of the nanocellulose/PEGDA hydrogel prepared with 1.8 per cent nanocellulose was 13.56, which increased by 44 per cent compared with that of the PEGDA hydrogel without nanocellulose. Originality/value The paper proposed a method for rapidly prototyping the nanocellulose with expected properties, which provided a theoretical basis and technological reference for the 3D additive manufacturing of nanocellulose 3D structure materials with a controlled accurate architecture.

A Parallel Multiple Layer Cryolithography Device for the Manufacture of Biological Material for Tissue Engineering

2019 ◽  
Vol 13 (3) ◽  
Author(s):  
Gideon Ukpai ◽  
Joseph Sahyoun ◽  
Robert Stuart ◽  
Sky Wang ◽  
Zichen Xiao ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Additive Manufacturing ◽  
3D Printing ◽  
3D Structure ◽  
Three Dimensional ◽  
3D Object ◽  
New Device ◽  
Biological Matter ◽  
Simple Product ◽  
Printing Processes

While three-dimensional (3D) printing of biological matter is of increasing interest, current linear 3D printing processes lack the efficiency at scale required to mass manufacture products made of biological matter. This paper introduces a device for a newly developed parallel additive manufacturing technology for production of 3D objects, which addresses the need for faster, industrial scale additive manufacturing methods. The technology uses multilayer cryolithography (MLCL) to make biological products faster and in larger quantities by simultaneously printing two-dimensional (2D) layers in parallel and assembling the layers into a 3D structure at an assembly site, instead of sequentially and linearly assembling a 3D object from individual elements as in conventional 3D printing. The technique uses freezing to bind the 2D layers together into a 3D object. This paper describes the basic principles of MLCL and demonstrates the technology with a new device used to manufacture a very simple product that could be used for tissue engineering, as an example. An evaluation of the interlayer bonding shows that a continuous and coherent structure can be made from the assembly of distinct layers using MLCL.

Continuous 3D-printing for additive manufacturing

2014 ◽  
Vol 20 (4) ◽  
pp. 320-327 ◽  
Author(s):  
Daniel Günther ◽  
Bastian Heymel ◽  
Johannes Franz Günther ◽  
Ingo Ederer
Keyword(s):  
Additive Manufacturing ◽  
3D Printing ◽  
Rapid Prototyping ◽  
Three Dimensional ◽  
Large Mass ◽  
Conveyor Belt ◽  
Particulate Material ◽  
Material System ◽  
Content Type ◽  
Particle Material

Purpose – This paper aims to present the results that can be achieved using continuous three-dimensional (3D) printing technology. Design/methodology/approach – In the first section, conventional additive manufacturing and continuous 3D-printing are described and compared against each other. Essential is the new approach to coat the particulate material and to print it on a tilted surface. For this special setup, theoretical considerations for sources of distortions are given. These considerations define the design of the test parts. For the evaluation of a tilted setup a prototype using large dimensions is shown. Of special interest is the exact transportation using a large mass of particulate material. Findings – The 3D-printing principle is suitable for tilted surfaces, making production without any downtime possible. The parts produced using the prototype continuous 3D-printer have sufficient accuracy for foundry use, although various considerations and the setup show that angular deflections can be caused by inaccuracies in the feeding system. Research limitations/implications – The parts’ accuracy is additionally affected by the thickness of unbound particle material under the building area. The amount of unbound particle material is of a constructive nature. Thus, the setup is limiting the investigations. Using the current material system, the printing should take place as near to the conveyor belt as possible. Practical implications – This paper outlines which kind of parts can be manufactured using continuous 3D-printing. Originality/value – This article shows a first evaluation of parts printed using continuous 3D-printing. It gives a perspective on future designs from rapid prototyping machines based on these principles and shows the possible benefits. The change over from rapid prototyping to rapid manufacturing will be strongly accelerated by said machine design.

scholarly journals Efficient 3D printing via photooxidation of ketocoumarin based photopolymerization

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Xiaoyu Zhao ◽  
Ye Zhao ◽  
Ming-De Li ◽  
Zhong’an Li ◽  
Haiyan Peng ◽  
...  
Keyword(s):  
Additive Manufacturing ◽  
3D Printing ◽  
Visible Light ◽  
Light Exposure ◽  
Three Dimensional ◽  
3D Printer ◽  
Light Penetration ◽  
Viable Solution

AbstractPhotopolymerization-based three-dimensional (3D) printing can enable customized manufacturing that is difficult to achieve through other traditional means. Nevertheless, it remains challenging to achieve efficient 3D printing due to the compromise between print speed and resolution. Herein, we report an efficient 3D printing approach based on the photooxidation of ketocoumarin that functions as the photosensitizer during photopolymerization, which can simultaneously deliver high print speed (5.1 cm h−1) and high print resolution (23 μm) on a common 3D printer. Mechanistically, the initiating radical and deethylated ketocoumarin are both generated upon visible light exposure, with the former giving rise to rapid photopolymerization and high print speed while the latter ensuring high print resolution by confining the light penetration. By comparison, the printed feature is hard to identify when the ketocoumarin encounters photoreduction due to the increased lateral photopolymerization. The proposed approach here provides a viable solution towards efficient additive manufacturing by controlling the photoreaction of photosensitizers during photopolymerization.

scholarly journals Advances in 3D Printing for Tissue Engineering

Materials ◽  
2021 ◽  
Vol 14 (12) ◽  
pp. 3149
Author(s):  
Angelika Zaszczyńska ◽  
Maryla Moczulska-Heljak ◽  
Arkadiusz Gradys ◽  
Paweł Sajkiewicz
Keyword(s):  
Tissue Engineering ◽  
Additive Manufacturing ◽  
3D Printing ◽  
Complex Structure ◽  
Three Dimensional ◽  
Computer Assisted ◽  
Scaffold Fabrication ◽  
Manufacturing Techniques ◽  
Printing Techniques ◽  
State Of Art

Tissue engineering (TE) scaffolds have enormous significance for the possibility of regeneration of complex tissue structures or even whole organs. Three-dimensional (3D) printing techniques allow fabricating TE scaffolds, having an extremely complex structure, in a repeatable and precise manner. Moreover, they enable the easy application of computer-assisted methods to TE scaffold design. The latest additive manufacturing techniques open up opportunities not otherwise available. This study aimed to summarize the state-of-art field of 3D printing techniques in applications for tissue engineering with a focus on the latest advancements. The following topics are discussed: systematics of the available 3D printing techniques applied for TE scaffold fabrication; overview of 3D printable biomaterials and advancements in 3D-printing-assisted tissue engineering.

A review on the role of 3D printing in the fight against COVID-19: safety and challenges

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Sapam Ningthemba Singh ◽  
Vavilada Satya Swamy Venkatesh ◽  
Ashish Bhalchandra Deoghare
Keyword(s):  
Supply Chain ◽  
3D Printing ◽  
Three Dimensional ◽  
Content Type ◽  
Medical Supplies ◽  
Future Challenges ◽  
Safety And Reliability ◽  
3D Printed ◽  
Comprehensive Study

Purpose During the COVID-19 pandemic, the three-dimensional (3D) printing community is actively participating to address the supply chain gap of essential medical supplies such as face masks, face shields, door adapters, test swabs and ventilator valves. This paper aims to present a comprehensive study on the role of 3D printing during the coronavirus (COVID-19) pandemic, its safety and its challenges. Design/methodology/approach This review paper focuses on the applications of 3D printing in the fight against COVID-19 along with the safety and challenges associated with 3D printing to fight COVID-19. The literature presented in this paper is collected from the journal indexing engines including Scopus, Google Scholar, ResearchGate, PubMed, Web of Science, etc. The main keywords used for searches were 3D printing COVID-19, Safety of 3D printed parts, Sustainability of 3D printing, etc. Further possible iterations of the keywords were used to collect the literature. Findings The applications of 3D printing in the fight against COVID-19 are 3D printed face masks, shields, ventilator valves, test swabs, drug deliveries and hands-free door adapters. As most of these measures are implemented hastily, the safety and reliability of these parts often lacked approval. The safety concerns include the safety of the printed parts, operators and secondary personnel such as the workers in material preparation and transportation. The future challenges include sustainability of the process, long term supply chain, intellectual property and royalty-free models, etc. Originality/value This paper presents a comprehensive study on the applications of 3D printing in the fight against COVID-19 with emphasis on the safety and challenges in it.

Effect of 3D printer enabled surface morphology and composition on coral growth in artificial reefs

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Ilse Valenzuela Matus ◽  
Jorge Lino Alves ◽  
Joaquim Góis ◽  
Augusto Barata da Rocha ◽  
Rui Neto ◽  
...  
Keyword(s):  
Additive Manufacturing ◽  
Chemical Composition ◽  
Chemical Elements ◽  
Three Dimensional ◽  
Coral Growth ◽  
Coralline Algae ◽  
Textured Surface ◽  
Crustose Coralline Algae ◽  
Statistical Parameters ◽  
Content Type

Purpose The purpose of this paper is to prove and qualify the influence of textured surface substrates morphology and chemical composition on the growth and propagation of transplanted corals. Use additive manufacturing and silicone moulds for converting three-dimensional samples into limestone mortar with white Portland cement substrates for coral growth. Design/methodology/approach Tiles samples were designed and printed with different geometries and textures inspired by nature marine environment. Commercial coral frag tiles were analysed through scanning electron microscopy (SEM) to identify the main chemical elements. Raw materials and coral species were selected. New base substrates were manufactured and deployed into a closed-circuit aquarium to monitor the coral weekly evolution process and analyse the results obtained. Findings Experimental results provided positive statistical parameters for future implementation tests, concluding that the intensity of textured surface, interfered favourably in the coralline algae biofilm growth. The chemical composition and design of the substrates were determinant factors for successful coral propagation. Recesses and cavities mimic the natural rocks aspect and promoted the presence and interaction of other species that favour the richness of the ecosystem. Originality/value Additive manufacturing provided an innovative method of production for ecology restoration areas, allowing rapid prototyping of substrates with high complexity morphologies, a critical and fundamental attribute to guarantee coral growth and Crustose Coralline Algae. The result of this study showed the feasibility of this approach using three-dimensional printing technologies.

3 D printing technology and experimental study of chitosan gel using atomized solidification liquid-assisted extrusion molding

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Yangwei Wang ◽  
Peilun Lv ◽  
Jian Li ◽  
Liying Yu ◽  
Guodong Yuan ◽  
...  
Keyword(s):  
3D Printing ◽  
Three Dimensional ◽  
Theoretical Research ◽  
Error Sources ◽  
Printing Technology ◽  
Content Type ◽  
Printing Ink ◽  
Printing Parameters ◽  
Chitosan Gel ◽  
Printing Method

Purpose This paper aims to propose a suitable atomizing solidification chitosan (CS) gel liquid extrusion molding technology for the three dimensional (3D) printing method, and experiments verify the feasibility of this method. Design/methodology/approach This paper mainly uses experimental means, combined with theoretical research. The preparation method, solidification forming method and 3D printing method of CS gel solution were studied. The CS gel printing mechanism and printing error sources are analyzed on the basis of the CS gel ink printing results, printing performance with different ratios of components by constructing a gel print prototype, experiments evaluating the CS gel printing technology and the effects of the process parameters on the scaffold formation. Findings CS printing ink was prepared; the optimal formula was found; the 3 D printing experiment of CS was completed; the optimal printing parameters were obtained; and the reliability of the forming prototype, printing ink and gel printing process was verified, which allowed for the possibility to apply the 3 D printing technology to the manufacturing of a CS gel structure. Originality/value This study can provide theoretical and technical support for the potential application of CS 3 D printed gels in tissue engineering.

Research on the printing error of tilted vertical beams in delta-robot 3D printers

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Yuezong Wang ◽  
Jinghui Liu ◽  
Mengfei Guo ◽  
LiuQIan Wang
Keyword(s):  
3D Printing ◽  
Kinematic Model ◽  
Three Dimensional ◽  
3D Printer ◽  
Simulation Approach ◽  
Content Type ◽  
Printing Quality ◽  
Delta Robot ◽  
Error Generation ◽  
Error Simulation

Purpose A three-dimensional (3D) printing error simulation approach is proposed to analyze the influence of tilted vertical beams on the 3D printing accuracy. The purpose of this study is to analyze the influence of such errors on printing accuracy and printing quality for delta-robot 3D printer. Design/methodology/approach First, the kinematic model of a delta-robot 3D printer with an ideal geometric structure is proposed by using vector analysis. Then, the normal kinematic model of a nonideal delta-robot 3D robot with tilted vertical beams is derived based on the above ideal kinematic model. Finally, a 3D printing error simulation approach is proposed to analyze the influence of tilted vertical beams on the 3D printing accuracy. Findings The results show that tilted vertical beams can indeed cause 3D printing errors and further influence the 3D printing quality of the final products and that the 3D printing errors of tilted vertical beams are related to the rotation angles of the tilted vertical beams. The larger the rotation angles of the tilted vertical beams are, the greater the geometric deformations of the printed structures. Originality/value Three vertical beams and six horizontal beams constitute the supporting parts of the frame of a delta-robot 3D printer. In this paper, the orientations of tilted vertical beams are shown to have a significant influence on 3D printing accuracy. However, the effect of tilted vertical beams on 3D printing accuracy is difficult to capture by instruments. To reveal the 3D printing error mechanisms under the condition of tilted vertical beams, the error generation mechanism and the quantitative influence of tilted vertical beams on 3D printing accuracy are studied by simulating the parallel motion mechanism of a delta-robot 3D printer with tilted vertical beams.

Animal orthosis fabrication with additive manufacturing – a case study of custom orthosis for chicken

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Wiktoria Maria Wojnarowska ◽  
Jakub Najowicz ◽  
Tomasz Piecuch ◽  
Michał Sochacki ◽  
Dawid Pijanka ◽  
...  
Keyword(s):  
Veterinary Medicine ◽  
Additive Manufacturing ◽  
Computer Aided Design ◽  
Three Dimensional ◽  
Fused Deposition Modelling ◽  
Content Type ◽  
Fused Deposition ◽  
Secondary Objective ◽  
Traditional Manufacturing ◽  
Aided Design

Purpose Chicken orthoses that cover the ankle joint area are not commercially available. Therefore, the main purpose of this study is to fabricate a customised temporary Ankle–Foot Orthosis (AFO) for a chicken with a twisted ankle using computer-aided design (CAD) and three-dimensional (3D) printing. The secondary objective of the paper is to present the specific application of Additive Manufacturing (AM) in veterinary medicine. Design/methodology/approach The design process was based on multiple sketches, photos and measurements that were provided by the owner of the animal. The 3D model of the orthosis was made with Autodesk Fusion 360, while the prototype was fabricated using fused deposition modelling (FDM). Evaluation of the AFO was performed using the finite element method. Findings The work resulted in a functional 3D printed AFO for chicken. It was found that the orthosis made with AM provides satisfactory stiffen and a good fit. It was concluded that AM is suitable for custom bird AFO fabrication and, in some respects, is superior to traditional manufacturing methods. It was also concluded that the presented procedure can be applied in other veterinary cases and to other animal species and other parts of their body. AM provides veterinary with a powerful tool for the production of well-fitted and durable orthoses for animals. Research limitations/implications The study does not include the chicken's opinion on the comfort or fit of the manufactured AFO due to communication issues. Evaluation of the final prototype was done by the researchers and the animal owner. Originality/value No evidence was found in the literature on the use of AM for chicken orthosis, so this study is the first to describe such an application of AM. In addition, the study demonstrates the value of AM in veterinary medicine, especially in the production of devices such as orthoses.

Algorithm to Reduce Leading and Lagging in Conformal Direct-Print

2018 ◽  
Vol 140 (10) ◽  
Author(s):  
Morteza Vatani ◽  
Faez Alkadi ◽  
Jae-Won Choi
Keyword(s):  
Additive Manufacturing ◽  
3D Printing ◽  
3D Model ◽  
Three Dimensional ◽  
Motion Direction ◽  
B Spline ◽  
And Topology ◽  
Printing System ◽  
3D Printed ◽  
Printed Patterns

A novel additive manufacturing algorithm was developed to increase the consistency of three-dimensional (3D) printed curvilinear or conformal patterns on freeform surfaces. The algorithm dynamically and locally compensates the nozzle location with respect to the pattern geometry, motion direction, and topology of the substrate to minimize lagging or leading during conformal printing. The printing algorithm was implemented in an existing 3D printing system that consists of an extrusion-based dispensing module and an XYZ-stage. A dispensing head is fixed on a Z-axis and moves vertically, while the substrate is installed on an XY-stage and moves in the x–y plane. The printing algorithm approximates the printed pattern using nonuniform rational B-spline (NURBS) curves translated directly from a 3D model. Results showed that the proposed printing algorithm increases the consistency in the width of the printed patterns. It is envisioned that the proposed algorithm can facilitate nonplanar 3D printing using common and commercially available Cartesian-type 3D printing systems.

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