Blood flow generation in b-mode ultrasound images of the carotidartery

Author(s):  
A.K. Hamou ◽  
M.R. El-Sakka
2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Xia Gao ◽  
Qiuying Li ◽  
Yanwen Qu ◽  
Jinzhi Zhang ◽  
Yougang Xing ◽  
...  

Objective. To study the clinical efficacy of integrated traditional Chinese medicine (TCM) and Western medicine (WM) in treating endometrial cancer and the influence on ultrasound, magnetic resonance imaging (MRI), tumor markers, human epididymis protein 4 (HE4) and carbohydrate antigen 125 (CA125). Method. A total of 152 cases of patients with endometrial carcinoma were randomly divided into two groups: the TCM + WM group and the WM group. The WM group was treated with megestrol acetate tablets, and the TCM + WM group was treated with Radix Astragali injection on the basis of the control group. The levels of inflammatory factors, HE4 and CA125 in serum, were detected using enzyme-linked immunosorbent assay (ELISA) or radioimmunoassay. The characteristics of ultrasound images and MRI images were observed and recorded. Toxicity, side effects, and the 3-year cumulative survival rate after treatment were assessed. Results. After treatment, the levels of interleukin-4 (IL-4), tumor necrosis factor-alpha (TNF-α), and high-sensitivity C-reactive protein (hs-CRP) in both groups decreased, and the decrease in the TCM + WM group was more obvious than that in the WM group. There were statistically significant differences between the two groups in lesion shape, boundary, blood flow signal, lesion diameter, resistance index (RI), echo, intima thickness, and muscle layer infiltration from transvaginal ultrasound images after treatment. The diameter, echo, boundary, shape, composition, and enhancement degree of lesions between the two groups have a significant difference. Moreover, the levels of serum HE4 and CA125 in both groups decreased after treatment, and the decrease in the TCM + WM group was more obvious than that in the WM group. There were statistically significant differences between the two groups in the occurrence of myelosuppression, abnormal liver function, decreased platelet number, gastrointestinal reactions, leukopenia, and cardiotoxicity. After three years of follow-up, the cumulative survival rate of the TCM + WM group was 76.32%, and the cumulative survival rate of the WM group was 57.89%. Conclusion. Radix Astragali injection combined with megestrol acetate tablets has obvious therapeutic effects against endometrial cancer. Through vaginal ultrasonography and MRI, it can significantly improve the size, shape, and blood flow signals of patients’ lesions, reduce the level of serum inflammatory factors and tumor markers HE4 and CA125, reduce the incidence of toxic and side reactions, improve the patient’s immunity, improve the patient’s condition significantly, and prolong the survival time of patients.


2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Xing-xin Liang ◽  
Fan Li ◽  
Feng Gao ◽  
Chun-xiao Li ◽  
Xiao-hui Qiao ◽  
...  

This study was to explore the significance of ultrasound in determining whether the patients with secondary hyperparathyroidism (SHPT) are sensitive to calcitriol treatment. According to the decrease value of parathyroid hormone (PTH), 42 SHPT patients were divided into two groups: drug susceptible group and drug insusceptible group. These 42 SHPT patients’ ultrasound images were retrospectively analyzed. The morphology, size, number, blood flow, elastic modulus, and perfusion of the parathyroid glands were correlated with drug therapeutic outcome (oral calcitriol). Most SHPT patients with drug susceptible showed volume <438.50 mm3and number ≤2, with 0-1 structural and vascular patterns, associated with Relative Maximum Intensity (RIMAX) <1.59 and elastic modulus <18.8 kPa, whereas most SHPT patients with drug insusceptible showed volume ≥438.50 mm3and number ≥3, with 2-3 structural and vascular patterns, associated with Relative Maximum Intensity (RIMAX) ≥1.59 and elastic modulus ≥18.8 kPa. Therefore, ultrasonography in SHPT allows an accurate definition of the morphology, size, number, blood flow, elastic modulus, and perfusion of the parathyroid glands and is useful in determining whether SHPT patients are sensitive to calcitriol treatment.


2003 ◽  
Vol 9 (3) ◽  
pp. 183-188 ◽  
Author(s):  
Gardar Sigurdsson ◽  
Demetris Yannopoulos ◽  
Scott H. McKnite ◽  
Keith G. Lurie

Author(s):  
Shinnosuke Hirata ◽  
Yuki Hagihara ◽  
Kenji YOSHIDA ◽  
Tadashi YAMAGUCHI ◽  
Matthieu E. G. Toulemonde ◽  
...  

Abstract In contrast enhancement ultrasound (CEUS), the vasculature image can be formed from nonlinear echoes arising from microbubbles in a blood flow. The use of binary-coded pulse compression is promising for improving the contrast of CEUS images by suppressing background noise. However, the amplitudes of nonlinear echoes can be reduced, and sidelobes by nonlinear echoes can occur depending on the binary code. Optimal Golay codes with slight nonlinear-echo reduction and nonlinear sidelobe have been proposed. In this study, CEUS images obtained by optimal Golay pulse compression are evaluated through experiments using Sonazoid microbubbles flowing in a tissue-mimicking phantom.


Author(s):  
Abigail Swillens ◽  
Lasse Løvstakken ◽  
Thomas De Schryver ◽  
Hans Torp ◽  
Patrick Segers

Ultrasonic imaging is widely applied for visualization of blood flow using different imaging modalities. However, due to the inherent physical limitations of the ultrasonic imaging process, the actual flow dynamics and the information embedded in the ultrasound image do not necessarily strictly correspond. Computational fluid dynamics (CFD) can play an important role in interpreting and improving ultrasound imaging via numerical simulation of ultrasound images. For this purpose, CFD velocity data can be directly processed to mimic ultrasonic images (1st order approach) or can be further coupled to ultrasound simulation software, providing a fully coupled approach. We compared both methods for the clinically relevant case of color flow imaging of the carotid artery. We conclude that for this application, the 1st order approach leads to results lacking indispensable properties of the imaging process, i.e., (i) the imaging dynamics, and (ii) the statistical properties of the ultrasonic velocity estimator.


2002 ◽  
Vol 93 (1) ◽  
pp. 361-368 ◽  
Author(s):  
Daniel Green ◽  
Craig Cheetham ◽  
Chris Reed ◽  
Lawrie Dembo ◽  
Gerry O'Driscoll

We describe a novel software system that utilizes automated algorithms to perform edge detection and wall tracking of high-resolution B-mode arterial ultrasound images, combined with synchronized Doppler waveform envelope analysis, to calculate conduit arterial blood flow (BF) across the cardiac cycle. Furthermore, we describe changes in brachial arterial BF to the resting forearm during incremental cycle ergometry in eight subjects. During exercise, peak BF during the cardiac cycle increased at each workload ( P < 0.001), because of increased velocity in the presence of unaltered cross-sectional area. In contrast, mean BF calculated across each cardiac cycle decreased at lower workloads before increasing at 100 and 160 W ( P< 0.001). Differences in the pattern of peak and mean cardiac cycle flows were due to the influence of retrograde diastolic flow, which had a larger impact on mean flows at lower workloads. In conclusion, BF can be measured with high temporal resolution across the cardiac cycle in humans. Resting brachial arterial flow, including retrograde flow, increases during lower limb exercise.


2014 ◽  
Vol 26 (04) ◽  
pp. 1440005
Author(s):  
Chuan-Yu Chang ◽  
Yuh-Shyan Tsai ◽  
Chuan-Wang Chang ◽  
Cheng-Min Fan

In order to detect early prostate cancer, physicians usually apply the ultrasound imaging to visualize prostate for diagnosis. However, the traditional gray-scale ultrasound images that obtained from transrectal ultrasound of the prostate are often limited in diagnosing prostate cancer because of cancer heterogeneity, which makes direct diagnosing on the image difficult. Power Doppler ultrasound images improve the diagnosis by providing extra information of blood flow. Previous study has shown that increased blood inflow exists in prostate cancer. It is not difficult to differentiate the malignancy from benign prostate diseases by inspecting Doppler spectrum at bilateral neurovascular bundle sites and using resistive index. Although it is effective; however, it is hand-held, time-consuming, and only limited in a small and static region, which might not represent the real status of the whole prostate. Therefore, this study proposed an integrated dynamic approach to estimate the resistive index of blood flow in regions of interest within or all over the whole prostate. Merits of the proposed approach include the follows: resistive index can be calculated in serial prostate frames; the calculation can be performed on integral prostate region; and the proposed approach shortened the time needed to complete the calculation on whole prostate. Experimental results show that dynamic resistive index is better than conventional resistive index, and comparable with Prostate specific antigen (PSA) test in diagnosing prostate cancer, indicating high performance of the proposed approach, which also reveals feasibility and effectively of it.


2019 ◽  
Vol 184 (Supplement_1) ◽  
pp. 386-391
Author(s):  
Florence H Sheehan ◽  
Shannon McConnaughey ◽  
Rosario Freeman ◽  
R Eugene Zierler

Abstract Background We developed simulator-based tools for assessing provider competence in transthoracic echocardiography (TTE) and vascular duplex scanning. Methods Psychomotor (technical) skill in TTE image acquisition was calculated from the deviation angle of an acquired image from the anatomically correct view. We applied this metric for formative assessment to give feedback to learners and evaluate curricula. Psychomotor skill in vascular ultrasound was measured in terms of dexterity and image plane location; cognitive skill was assessed from measurements of blood flow velocity, parameter settings, and diagnosis. The validity of the vascular simulator was assessed from the accuracy with which experts can measure peak systolic blood flow velocity (PSV). Results In the TTE simulator, the skill metric enabled immediate feedback, formative assessment of curriculum efficacy, and comparison of curriculum outcomes. The vascular duplex ultrasound simulator also provided feedback, and experts’ measurements of PSV deviated from actual PSV in the model by &lt;10%. Conclusions Skill in acquiring diagnostic ultrasound images of organs and vessels can be measured using simulation in an objective, quantitative, and standardized manner. Current applications are provision of feedback to learners to enable training without direct faculty oversight and formative assessment of curricula. Simulator-based metrics could also be applied for summative assessment.


Animals ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 2339
Author(s):  
Francisco Requena ◽  
María Joana A. P. M. Campos ◽  
Andrés Luis Martínez Marín ◽  
Rocío Camacho ◽  
Rosa M. Giráldez-Pérez ◽  
...  

In equine reproduction, accurate and timely detection of the moment of ovulation is of great importance. Power Doppler ultrasound technology is a non-invasive method that enables to assess the morpho-echogenic features and blood flow changes during the estral cycle in mares. The objective of the present study was to evaluate the influence of age on ultrasonographic parameters (follicular diameter, follicular blood flow—FBF, corpus luteum (CL) area and corpus luteum blood flow—CLBF) and blood plasma progesterone concentrations in cycling Spanish Purebred mares (15 less than 8 years old and 15 equal o higher than 8 years old). The ultrasound images obtained were analyzed with the Image Colour Summarizer software, which allows the quantification of the pixels of each image. Young mares had significantly higher FBF, CLBF and plasma progesterone levels. Moreover, linear regression analysis showed that blood progesterone levels could be predicted in both groups from CLBF with moderate precision and accuracy. In conclusion, Power Doppler was useful to assess ovarian hemodynamics. Our results support that age is a factor that significantly influences FBF and CLBF as well as blood progesterone concentration in mares. More studies would be needed to develop high precision and accuracy predictive models of blood progesterone concentration from CLBF measured by Power Doppler.


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