Antioxidant Potency of Kaempferia galanga Linn and Zingiber officinale var. Rubra rhizomes

Author(s):  
Dian Ratih Laksmitawati ◽  
Wahyu Widowati ◽  
Hana Sari Widya Kusuma ◽  
Diah Kartika Pratami ◽  
Cahyaning Riski Wijayanti ◽  
...  
2018 ◽  
Vol 1 (1) ◽  
pp. 24 ◽  
Author(s):  
Meutia Zahara ◽  
Mauizah Hasanah ◽  
Rahma Zalianda

Zingiberaceae is well known as gingers family with abundant numbers of spices widely used in Southeast Asia, because of their unique flavors, ornamental and also the medicinal values. The extracts of Zingiberaceae rhizome contain many essentials oils, including terpenes, alcohols, ketones, flavonoids and phytoestrogens that use as medicine. Zingiberaceae grow vigorously in a wide range of habitats ranging from riverine to the limestone area, from lowland to the upper mountain regions. They often grow in shady area but some of the native species are able to tolerate to the sun exposure. The cultivation of this family was developed widely. Gunung Cut Village is one the villages in Aceh Barat Daya district which cultivated four species of this family: Zingiber officinale, Curcuma domestica, Alpina galanga and Kaempferia galanga. They mainly use for medicinal purposes as it can cure many diseases traditionally.


2018 ◽  
Vol 17 (1) ◽  
pp. 31
Author(s):  
Mohammad Fathi Royyani ◽  
Vera Budi Lestari ◽  
Andria Agusta ◽  
Oscar Efendy

This research was aimed to discover the traditional knowledge of Enggano people when using plants as concoction after giving birth. Data was collected through in depth interview, open-ended, and literature studies. The results showed that Enggano people used specific plants as concoction in childbirth process. There were two types of the concoction. The first was used after giving birth to 40 days, jarak pagar or tiarak (Jatropha curcas L.). The second was used after 40 days to 60 days or after recovery, such as dukung anak (Phyllanthus niruri Linn.), kumis kucing (Orthosiphon stamineus Benth.), temu lawak (Curcuma xanthoriza Roxb.), alang-alang (Imperata cylindrica (L) P. Beauv.), banana (Musa sp.), kencur (Kaempferia galanga L.), turmeric (Curcuma longa L.), and ginger (Zingiber officinale Roscoe). Results from our literature studies confirmed the efficacy of plants used by Enggano people is scientifically acceptable. Further study on phytochemical aspects of these medicial plants is therefore required to be carried out.


2013 ◽  
Vol 62 (1) ◽  
Author(s):  
Zahidah Ayob ◽  
Alina Wagiran ◽  
Azman Abd Samad

Medicinal plants possess many secondary products that exhibit biological activities such as antioxidant, anticancer, anti-inflammatory, antibacterial and anti microbial. Scientific findings have demonstrated that tissue culture techniques could be an alternative tool to propagate plant in vitro and manipulate secondary metabolites in medicinal plants. This review aims to give an update on the various plant regeneration of some locally used medicinal plants in Malaysia such as Eurycome longifolia Jack, Zingiber officinale Roscoe, Centella asiatica L., Justicia gendarussa Burm. f, Kaempferia galanga L. and Orthosiphon stamineus Benth. Different type of cultures including organ, callus and cell cultures is also discussed.


2019 ◽  
Vol 3 (2) ◽  
pp. 211-214
Author(s):  
Aminah Dalimunthe ◽  
Masfria ◽  
Sumaiyah

Tujuan penelitian ini adalah untuk mengetahui daya terima masyarakat berdasatkan tingkat kesukaan rasa, aroma, warna, dan tekstur permen herbal dari kencur dan jahe merah . Penelitian ini dilakukan secara eksperimental menggunakan metode analisis statistik deskriptif. Hasil penelitian, menunjukkan bahwa tidak ada perbedaan signifikan terhadap tingkat kesukaan rasa, aroma, warna dan tekstur permen herbal dari kencur dan jahe merah (P>0,05) sehingga dapat disimpilkan bahwa masyarakat meyukai permen herbal dari kencur dan jahe merah.


Author(s):  
Arief Hidayatullah ◽  
Wira Eka Putra ◽  
Sustiprijatno ◽  
Galuh Wening Permatasari ◽  
Wa Ode Salma ◽  
...  

Dengue caused by the dengue virus (DENV) is a severe health problem in tropical regions such as Southeast Asia, especially Indonesia. Indonesian have used rhizome as traditional medicine for 1300 years. This study investigated the compounds from Kaempferia galanga, Curcuma longa, Zingiber officinale, Curcuma aeruginosa, Curcuma zanthorrhiza, Alpinia galanga, and Allium sativum as antivirals agents, explicitly targeting the DENV envelope protein to inhibit viral fusion. This study involved 121 bioactive compounds and DENV2's prefusion envelope protein. The virtual screening and molecular docking were done through occupied the Lipinski rule of five checker (http://www.scfbio-iitd.res.in/software/drugdesign/lipinski.jsp) and AutoDock Vina (https://pyrx.sourceforge.io/) respectively. The top nine compounds with the strongest binding affinity were galangin, kampferide, demetoxy curcumin, bisdemethoxycurcumin, β-selinene, 6-(hydroxymethyl)-1,4,4-trimethylbicyclo[3.1.0]hexan-2-ol, piperine, estra-1,3, 5(10)-trien-17β-ol, and curcumin. These compounds' affinity values were significantly lower, around 45-62%, than chloroquine. Most of them interact with the kl hairpin and hydrophobic pocket formed by residues Val130, Leu135, Phe193, Leu198, and Phe279of critical domains that can interfere with the conformational change and rearrangement of protein dimer in the post-fusion stage. This study suggested that the galangin, demethoxycurcumin, and bisdemethoxycurcumin are considered the most potential compounds to be developed as anti-prefusion E DENV2 low-affinity and intense interaction with those. Keywords: DENV2, envelope protein, in silico, viral fusion, viral infection


bionature ◽  
2020 ◽  
Vol 21 (2) ◽  
Author(s):  
Diah Meidatuzzahra ◽  
Rosalina Edy Swandayani

Abstract. One group of plants most used by Indonesians as traditional medicine are plants from the Zingiberaceae family. The aims this study is to assess the level of knowledge and use of the Zingiberaceae family as traditional medicine by the Sasak people in Suranadi Village, Narmada District. This research was conducted using a descriptive exploratory method, which is presented in tabular form. Data collection was carried out by direct observation and semi-structured interviews. Inventory and identification were carried out on the Zingiberaceae family plants found based on observations. Based on the results, it was found that 5 (five) types of medicinal plants in the Zingiberaceae family were used by the Sasak people, namely Jae (Zingiber officinale), Kunyiq (Curcuma longa), Sekoh (Kaempferia galanga), Temu mango (Curcuma amada), Temulawak (Curcuma xanthorrhiza)).Keywords: Zingiberaceae family, traditional medicine, Suranadi village.


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