Blood pressure dependence of systemic arterial compliance global effects

This study sought to examine whether cardiovascular performance during exercise, assessed using the vascular-ventricular coupling index (VVC), was affected by exaggerated blood pressure (EBP) responses in endurance-trained athletes. Subjects were middle-aged endurance-trained men and women. Blood pressure measurements and left ventricular echocardiography were performed in a semiupright position at rest and during steady-state cycling at workloads that elicited 100–110 beats/min ( stage 1) and 130–140 beats/min ( stage 2). These data were used to calculate effective arterial elastance index ( EaI), left ventricular end-systolic elastance index ( ELVI), and their ratio (VVC). Additional measurements of left ventricular volumes and function (i.e., stroke volume, cardiac output, and longitudinal strain) and indirect assessments of peripheral vascular function (i.e., total arterial compliance and peripheral vascular resistance) were examined. Fourteen subjects with EBP (EBP+, 50% men) and 14 sex-matched subjects without EBP (EBP−) participated, with results presented as EBP+ versus EBP−. EaI and ELVI increased from rest to exercise while VVC decreased, but only ELVI was different between groups at stage 1 [7.6 (1.8) vs. 6.4 (1.0) mmHg·ml−1·m−2, P = 0.045] and stage 2 [10.3 (1.6) vs. 8.0 (1.7) mmHg·ml−1·m−2, P < 0.001]. Additional comparisons revealed no group difference in the contribution of the Frank-Starling mechanism or left ventricular and peripheral vascular function during exercise. The cardiovascular adjustment to exercise in athletes with EBP is achieved through a matched increase in both EaI and ELVI, and the absence of between-group differences in left ventricular or peripheral vascular function suggests that other factors may contribute to the EBP response. NEW & NOTEWORTHY Cardiovascular performance during submaximal exercise, assessed using vascular-ventricular coupling, is unaffected by exaggerated blood pressure (EBP) responses in endurance-trained athletes. The underlying mechanisms of EBP in athletes remain unknown as changes in left ventricular and peripheral vascular function during exercise were similar in athletes with and without EBP.

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Rosiglitazone Lowers Blood Pressure and Increases Arterial Compliance in Postmenopausal Women With Type 2 Diabetes

Diabetes Care ◽

10.2337/diacare.26.11.3194 ◽

2003 ◽

Vol 26 (11) ◽

pp. 3194-3195 ◽

Cited By ~ 19

Author(s):

S. Y. Honisett ◽

L. Stojanovska ◽

K. Sudhir ◽

B. A. Kingwell ◽

T. Dawood ◽

...

Keyword(s):

Blood Pressure ◽

Type 2 Diabetes ◽

Postmenopausal Women ◽

Arterial Compliance

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Effect of unilateral resistance training on arterial compliance in elderly men

Applied Physiology Nutrition and Metabolism ◽

10.1139/h07-048 ◽

2007 ◽

Vol 32 (4) ◽

pp. 670-676 ◽

Cited By ~ 9

Author(s):

Fleur Poelkens ◽

Mark Rakobowchuk ◽

Kirsten A. Burgomaster ◽

Maria T.E. Hopman ◽

Stuart M. Phillips ◽

...

Keyword(s):

Blood Pressure ◽

Resistance Training ◽

Arterial Compliance ◽

Stiffness Index ◽

Elderly Men ◽

Arterial Diameter ◽

Healthy Elderly ◽

Arterial Blood ◽

The Impact ◽

Peak Blood

An increase in age coincides with a decrease in arterial compliance, which is related to a higher risk for cardiovascular accidents. Evidence regarding the effects of resistance training on arterial compliance is conflicting. Currently, little information is available about the effect of resistance training on arterial compliance in elderly men. We assessed the impact of 10 weeks of unilateral arm and leg resistance training on carotid, brachial, and femoral arterial compliance in 12 healthy elderly men (mean age ± SD, 71 ± 7 y). Arterial compliance was evaluated before, after 4 weeks, and after 10 weeks of unilateral resistance training by simultaneously measuring arterial diameter and blood pressure in each artery. There were no significant differences in arterial compliance or stiffness index in any of the arteries examined after 10 weeks of training. However, after 10 weeks of resistance training, resting heart rate decreased from 76 ± 4 beats/min to 61 ± 3 beats/min (p < 0.05), plasma glucose decreased from 6.0 ± 0.9 to 5.1 ± 0.9 mmol/L (mean ± SE) (p < 0.05), and carotid artery peak blood flow increased from 1831 mL/min to 2245 mL/min (p < 0.05). There were no significant changes in resting arterial blood pressure. Unilateral resistance training for 10 weeks does not alter peripheral and central arterial compliance elderly men.

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Relationship of Arterial Compliance and Blood Pressure with Microalbuminuria and Mildly Decreased Glomerular Filtration Rate: A Chinese Community-Based Analysis

PLoS ONE ◽

10.1371/journal.pone.0101013 ◽

2014 ◽

Vol 9 (6) ◽

pp. e101013 ◽

Cited By ~ 1

Author(s):

Shihui Fu ◽

Yuqing Sun ◽

Leiming Luo ◽

Ping Ye

Keyword(s):

Blood Pressure ◽

Glomerular Filtration Rate ◽

Glomerular Filtration ◽

Filtration Rate ◽

Arterial Compliance ◽

Chinese Community ◽

Community Based ◽

Relationship Of

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Single Pill Indapamide and Perindopril Arginine Combination: Optimal Coupling of Vascular Protection and Hemodynamic Risk Factors Reduction in Patients with Essential Arterial Hypertension

Kardiologiia ◽

10.18087/cardio.2019.3.10236 ◽

2019 ◽

Vol 59 (3) ◽

pp. 18-26 ◽

Cited By ~ 1

Author(s):

E. V. Borisova ◽

A. I. Kochetkov ◽

O. D. Ostroumova

Keyword(s):

Blood Pressure ◽

Arterial Stiffness ◽

Arterial Hypertension ◽

Arterial Compliance ◽

Stage Ii ◽

Stiffness Index ◽

Single Pill ◽

Essential Arterial Hypertension ◽

The Impact

Objective: to investigate the impact of indapamide / perindopril single-pill combination (I / P SPC) on arterial stiffness parameters, blood pressure (BP) level and BP variability (BPV) in middle-aged patients with stage II grade 1–2 essential arterial hypertension (EAH). Materials and methods. We retrospectively formed a group of patients with stage II grade 1–2 EAH who had not previously received regular antihypertensive therapy (AHT) (n=52, mean age 52.9±6.0 years). All patients were treated with I / P SPC and all of them achieved target office BP level (less than 140 / 90 mm Hg). After 12 weeks of follow-up (from the time of reaching the target BP) assessment of AHT effectiveness (general clinical data, ambulatory blood pressure monitoring [ABPM], volume sphygmography, echocardiography), and vascular stiffness evaluation were performed.Results. At the end of follow-up office systolic BP (SBP), diastolic BP (DBP), pulse BP, day-time, night-time and 24‑hour SBP and DBP significantly (p<0.001 for all) decreased. According to the ABPM data day-time, nighttime, and 24‑hour systolic BPV significantly decreased (p=0.029, p=0.006 and p<0.001, respectively); day-time and 24‑hour diastolic BPV also significantly decreased (p=0.001 and p<0.001, respectively). Day-night standard deviation (SDdn) significantly decreased too (p=0.002 and p<0.001, respectively). Volumetric sphygmography showed significant decrease of right cardio-ankle vascular index (CAVI) (from 8.20±1.29 to 7.58±1.44, p=0.001) and of left CAVI (from 8.13±1.40 to 7.46±1.43, p<0.001), as well as reduction of the number o f patients with a right- and / or left-CAVI >9.0 (from 32.7 to 11.5 %, p=0.018). According to assessment of arterial stiffness using the Vasotens24 software package, the arterial stiffness index (ASI) significantly (p<0.001) decreased from 153.5±29.9 to 138.3±20.0 (by –9.2±13.1 %). Transthoracic echocardiography data demonstrated significant decrease (p<0.001) in effective arterial elastance (from 1.82±0.43 to 1.58±0.36 mm Hg; by –11.85±16.29 %) and significant (p<0.001) increase in the arterial compliance – from 1.27±0.34 to 1.54±0.38 mm Hg / ml (+26.95±38.06 %).Conclusion. In AHT naive patients 40–65 years old with stage II grade 1–2 EAH therapy with I / P SPC provided effective 24‑hour BP control, reduced BPV and improved arterial stiffness parameters.

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Physical exercise in individuals in hemodialysis: benefits and best indications - systematic review

Revista Pesquisa em Fisioterapia ◽

10.17267/2238-2704rpf.v8i3.1933 ◽

2018 ◽

Vol 8 (3) ◽

pp. 404-419

Author(s):

Filipe Ferrari Ribeiro De Lacerda ◽

Marvyn de Santana Do Sacramento ◽

Diego Passos Diogo ◽

Alan Carlos Nery Dos Santos ◽

Marcelo Trotte Motta ◽

...

Keyword(s):

Quality Of Life ◽

Systematic Review ◽

Blood Pressure ◽

Physical Exercise ◽

Arterial Compliance ◽

Reduce Blood Pressure ◽

Number Of Patients ◽

Control Objective ◽

The Individual

INTRODUCTION: The number of patients with chronic chronic disease (CKD) on hemodialysis (HD) has increased. In Brazil, in 2012, the number of patients in HD was 97,586, with a mortality rate of 19%. Physical exercise (PE) is an adjuvant therapy capable of promoting glycemic control, blood pressure and other gains relevant to CKD control. OBJECTIVE: To describe the benefits of quality of life, care and the most effective protocols of physical exercise for the individual on hemodialysis. METHODS: Systematic review study. Consultations of the SciELO and PubMed databases between 2005 and 2016 on the physiological effects of exercise and the quality of life of the individual on hemodialysis. The cross-over descriptors used were: "hemodialysis" and "exercises", "hemodialysis" and "exercises" and "intradialitic" and "exercises". RESULTS: 23 articles were selected with different EF programs, 8 exercises, 6 resisted, 5 composed by the association of both, and 1 of a comparison between aerobic and resisted. A sample ranged from 6 to 103 patients. Intervention time of 2 to 4 months. All programs should be improved in relation to functional capacity, reduction of inflammation, improvement of arterial compliance and others. In resisted PE, one of the studies reported deleterious effects for the patients, while those with resisted and aerobic PE showed benefits. CONCLUSION: EF was able to prevent oxidative stress, reduce blood pressure and increase blood glucose, increase muscle volume and strength, and gain quality in life, but there was no agreement on the best protocol.

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Effect of physical activity on central arterial compliance and systolic blood pressure in middle and elderly humans

Taiikugaku kenkyu (Japan Journal of Physical Education Health and Sport Sciences) ◽

10.5432/jjpehss.kj00003401457 ◽

2004 ◽

Vol 49 (2) ◽

pp. 135-146 ◽

Cited By ~ 3

Author(s):

Takumi Tanabe ◽

Seiji Maeda ◽

Jun Sugawara ◽

Takeshi Otsuki ◽

Tetsuji Kakiyama ◽

...

Keyword(s):

Physical Activity ◽

Blood Pressure ◽

Systolic Blood Pressure ◽

Arterial Compliance ◽

Elderly Humans

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Estimation of blood pressure-related parameters by electrical impedance measurement

Journal of Applied Physiology ◽

10.1152/jappl.1992.73.5.1946 ◽

1992 ◽

Vol 73 (5) ◽

pp. 1946-1957 ◽

Cited By ~ 5

Author(s):

J. H. Muntinga ◽

K. R. Visser

Keyword(s):

Blood Pressure ◽

Blood Volume ◽

Electrical Impedance ◽

Cuff Pressure ◽

Arterial Compliance ◽

Blood Pressure Measurement ◽

Venous Blood ◽

Impedance Measurement ◽

Total Blood ◽

Arterial Blood

In 13 healthy volunteers a computerized experimental set-up was used to measure the electrical impedance of the upper arm at changing cuff pressure, together with the finger arterial blood pressure in the contralateral arm. On the basis of a model for the admittance response, the arterial blood volume per centimeter length (1.4 +/- 0.3 ml/cm), the venous blood volume as a percentage of the total blood compartment (49.2 +/- 12.6%), and the total arterial compliance as a function of mean arterial transmural pressure were estimated. The effective physiological arterial compliance amounted to 2.0 +/- 1.3 microliters.mmHg-1.cm-1 and the maximum compliance to 33.4 +/- 12.0 microliters.mmHg-1.cm-1. Additionally, the extravascular fluid volume expelled by the occluding cuff (0.3 +/- 0.3 ml/cm) was estimated. These quantities are closely related to patient-dependent sources of an unreliable blood pressure measurement and vary with changes in cardiovascular function, such as those found in hypertension. Traditionally, a combination of several methods is needed to estimate them. Such methods, however, usually neglect the contribution of extravascular factors.

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