Effect of a family history of psoriasis and age on comorbidities and quality of life in patients with moderate to severe psoriasis: Results from the ARIZONA study

2015 ◽  
Vol 43 (4) ◽  
pp. 395-401 ◽  
Author(s):  
Jose Luis López-Estebaranz ◽  
Jose Luis Sánchez-Carazo ◽  
Sara Sulleiro
2018 ◽  
Vol 89 (2) ◽  
pp. 187-205 ◽  
Author(s):  
Kyle S. Page ◽  
Bert Hayslip ◽  
Dee Wadsworth ◽  
Philip A. Allen

Persons with and without a family history of dementia report concerns for developing this syndrome; yet, less is known about the specific aspects of dementia that are feared. The Fear of Dementia (FOD) scale was created to assess these concerns. This study examined the psychometric properties of the FOD scale using a sample of middle-aged and older adults ( N = 734). We then explored the factor structure of the scale 2 years later using a smaller sample from the first study ( N = 226). Three factors emerged, highlighting several main areas of concern: Burden and Loss, Quality of Life, and Perceived Social and Cognitive Loss. Preliminary data suggest that the FOD scale is a reliable and valid instrument for assessing the multidimensional nature of the concern about developing dementia. Attention to what specifically is feared may help further our understanding of health behaviors, coping, and targeted supports.


2020 ◽  
Vol 8 (2) ◽  
pp. 85-90
Author(s):  
Shifa Shaffique ◽  
Haseeb Anwar ◽  
Hafiz Muhammad Asif ◽  
Imran ul Haq ◽  
Muhammad Akram

Aim: Population based studies on prevalence of hyperthyroidism and its impact on quality of life, with variability of weight, height and distribution, their associated symptoms are limited. Knowledge and awareness about the prevalence of hyperthyroidism and their associated symptoms and its treatment option is necessary for the patient education and evaluation of underlying causative factors of this disease. Methodology: Apopulation-based study was conducted from October 2018 to May 2019 to determine the prevalence of hyperthyroidism and its impact on quality of life among the students of The Islamia University Bahawalpur. Questioner were developed and distributed among the consenting participants. Thirty-six males and one hundred and six females were included in this study. Results: Our study concluded that prevalence of hyperthyroidism is n=10(6.6%) and its prevalence ishigher in middle class families. Hyperthyroidism has a positive link with family history and previous history as shown in the results i.e. n=8 (5.3%) with family history and n=5 (3.3%) linked with previoushistory. It is the leading cause of morbidity and its prevalence is raised day by day. We studied that hyperthyroidism produces following effects on quality of life; n=10 (6.6%) participants were presented with loss of concentration in work / studies=10 (6.6%) with body ache, n=8 (5.3%) with social isolation, n=10 (6.6%) with mental health changes, n=6 (4%) with a history of previous treatment, n=8 (5.3%) with need of repeated checkups. Conclusion: It is concluded from present study that the hypehyperthyroidism significantly affects the quality of life and it is positively linked with the family history and history.


Author(s):  
Rehan Ahmad Khan Sherwani ◽  
Sajjad Ali Gill ◽  
Saba Younus ◽  
Sana Saeed ◽  
Nadia Saeed ◽  
...  

Introduction: The objectives of this study is to determine the risk factors of lung cancer were patients and investigate the quality of life of lung cancer survivors. The occupational, smoking, personal, environmental and family history of the survivors are investigated. The well-being of the survivors with physical and social norms not were also studied. Methods: Risk factors and quality of life from a sample of 50 lung cancer patients investigated through a self-administered questionnaire after getting consent from the hospital management and the patients. All the analysis has been done in SPSS 21. Results: Most of the lung cancer patients were male smokers with a strong history of smoking, and more than half of the respondents inhaled while smoking cigarettes. The significant risk factors among non-smokers are occupational history, personal history, environmental history, and family history. The impact of environmental history with smoking history is observed in lung cancer patients. The physical well-being of the patients is considerably affected by the disease and the pain in their daily activities. Conclusion: Smoking remained the leading risk factor of lung cancer patients followed by radon. However, family history is found statistically significant in the prevalence of lung cancer. Authorities should draw and implement some guiding rules to control smoking, radon, and air pollution, particularly in residential areas.


Author(s):  
Suganya Sekar ◽  
Samuel J. Daniel

<p class="abstract"><strong>Background:</strong> Psoriasis is a chronic disorder with the most common manifestation being the plaque-type. Nearly 20% of the plaque type suffer from a disease of moderate to severe intensity with immense effect on the quality of life. Aim was to study the clinical, socio-economic and demographic characteristics of patients with moderate to severe plaque type of psoriasis.</p><p class="abstract"><strong>Methods:</strong> This was an observational study conducted in about fourty patients diagnosed with moderate to severe plaque type of psoriasis based upon the clinical history, morphology of the lesions and assessed using psoriasis area and severity index (PASI), dermatology life quality index (DLQI) scoring and for comorbidities. Data was compiled and analyzed with statistical package for social science (SPSS) Version 20.0.</p><p class="abstract"><strong>Results:</strong> Mean age was 37.43±10.1 years. 22 were males (55%) and 18 were females (45%). The mean duration was 8.93 years and 15% had family history. The mean age of onset was earlier in the females (20.23 years) with a positive family history, as compared to males (25.36 years). About 62.5% had moderate psoriasis and 37.5% had severe psoriasis. At the baseline the PASI score was 31.98±6.08 and DLQI score was 36. About 67.5% had nail changes and 10% had psoriatic arthritis. Almost in half (47.5%) the duration of the disease was 1 to 5 years and scalp (32.5%) the most common initial site of involvement. Various comorbidities were documented, 72% in moderate psoriasis and 73.33% in severe psoriasis with dyslipidemia (67.5%) being commonest.</p><p class="abstract"><strong>Conclusions:</strong> Patients with moderate to severe psoriasis mostly have a low quality of life with multiple significant co-morbidities that increases the risk for morbidity and mortality.  </p>


Author(s):  
Abigail Garrity ◽  
Trudy Lerer ◽  
Anthony Otley ◽  
James Markowitz ◽  
Anne Griffiths ◽  
...  

2020 ◽  
Vol 9 (1) ◽  
Author(s):  
Farnaz Jahhantigh ◽  
Fateme Behmaneshpour ◽  
Fatemaeh Gharebaghi

Background: Celiac disease (CD) is a chronic, systemic immune disorder that can affect one’s quality of life. Objectives: The aim of this study was to explore the key performance indicators (KPIs) related to the quality of life of patients with CD admitted to the Celiac Association of Bouali Hospital in Zahedan. Methods: This descriptive-analytical study was performed on 60 patients with CD who referred to the Celiac Association of Bouali Hospital in Zahedan in 2018. Data collection tools included a demographic questionnaire (age, gender, marital status, duration of illness, education, ethnicity, economic status, occupation, breastfeeding history, family history of CD, as well as vitamin D and iron supplementation) and the Quality of Life Questionnaire for patients with CD. Data were analyzed in SPSS 21 using descriptive statistics. All values less than 0.05 were considered statistically significant. Results: Sixty participants completed the study, 66.7% of whom were female, 76.7% were married, and 85.3% reported a family history of CD. The total score of patients’ quality of life was 81.66 ± 18.33, and the lowest score of quality of life was associated with patients’ concerns (51.81 ± 3.85). The findings also showed that, among various KPIs, vitamin D had a particularly significant relationship with patients’ quality of life. Conclusions: There was a significant relationship between the quality of life and vitamin D supplementation in the participants. Besides, considering the effect of physical health on improving the quality of life and the chronic nature of CD, it is necessary to enhance the quality of life of these individuals by raising their awareness about micronutrient intakes while respecting their dietary restrictions.


2019 ◽  
Vol 76 (7) ◽  
pp. 716-722
Author(s):  
Sladjana Vasiljevic ◽  
Marina Petrovic ◽  
Aleksandra Cvetkovic ◽  
Vesna Paunovic ◽  
Darko Mikic ◽  
...  

Background/Aim. Chronic obstructive pulmonary disease (COPD) has a significant impact on quality of life of patients. We investigated which demographic and social characteristics can predict the global quality of life (QoL) of COPD patients. Methods. The patients (n = 288) were divided into three groups according to the stage of disease: Group I = stage 0 ? at risk; Group II = Stages I and II; Group III = stages III and IV. The patients fulfilled a questionnaire related to the demographic and social characteristics and the validated multidimensional questionnaire ? Serbian version of the St. George?s Respiratory Questionnaire (SGRQ). The Student?s t test, ?? test, ANOVA, univariate and multivariate logistic regression tests were used for statistical analyses. Results. In the group I, prevailed the men, employed persons, with a moderate financial status and no family history of COPD. In the group II dominated women, pensioners, with a moderate financial status, duration of illness up to five years, and no family history of COPD. In the group III prevailed women, unemployed persons, a moderate financial status, COPD duration up to 5 years and no family history of COPD. The predictors of the Symptoms score were grades of COPD and duration of the disease, and the predictors of Activity grades of COPD, sex, age and financial status. All variables were found to have a statistically significant relationship in the Impact score in the pre-analyses, were also significant in the univariate regression model. They were age, employement status, financial status and COPD duration. The same predictors that significantly contributed to the explanation of the Impact score, contributed to the explanation of the Total score on SGRQ. In the multivariate regression model, the predictors of the Activity score, Impacts score and Total score were the COPD grade and financial status; only the COPD grade contributed to the explanation of the Symptoms score. Conclusion. Financial status is the most important social factor, and the grade of COPD is the best disease-related predictor of QoL of COPD patients.


2020 ◽  
Vol 24 (2) ◽  
pp. 128-133
Author(s):  
Shahzad Haider ◽  
Tahir Mahmood ◽  
Sajjad Hussain ◽  
Sajid Nazir ◽  
Sidra Shafiq ◽  
...  

Objective: To assess the Quality Of Life (QOL) in children with epilepsy using modified QOLCE-55 questionnaire. Material and Methods: We consecutively enrolled children aged 4 to 16 years who were under treatment for childhood epilepsy. Basic demographic and clinical details including type of epilepsy, developmental history, family history of epilepsy and any co-morbidity were recorded in a predesigned Performa. QOL was evaluated by using modified QOLCE-55 (39 items) from parents. Results: A total of 54 children were enrolled in the study, 42 (78%) were males and 12(22%) were female children with epilepsy.  Eight children got good QOLCE score, while 24 children had average and 22 children got a poor score. The good score was mostly seen in 4-8 years (40%) of age while the poor score was seen in 12-16 years (70%) age group. Age of the patients (p=<0.001), gender (p=<0.001), associated co-morbidities (p=0.003) and family history of epilepsy (p=0.011) showed a significant effect on the QOLCE score. Type of epilepsy (p= 0.825) and development of a child (p=0.109) did not affect the QOLCE score significantly. Conclusion: The study showed that Children with co-morbidities, family history of epilepsy and female children of older age group (12-16 years) had poor QOL. Types of seizures and development of the child did not significantly alter the QOLCE score.


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