scholarly journals Does very early timing of lymph node surgery after resection of the primary tumour improve the clinical outcome of patients with melanoma?

2020 ◽  
Vol 45 (8) ◽  
pp. 1011-1018 ◽  
Author(s):  
T. Gambichler ◽  
H. Bünnemann ◽  
C. H. Scheel ◽  
F. G. Bechara ◽  
M. Stücker ◽  
...  
Keyword(s):  
Lymph Node ◽  
Clinical Outcome ◽  
Primary Tumour ◽  
Early Timing

Tonic-clonic seizures as first symptom of a disseminated supraglottic laryngeal cancer

2020 ◽  
Vol 13 (3) ◽  
pp. e233584
Author(s):  
Christian Danstrup ◽  
Maria Andersen
Keyword(s):  
Lymph Node ◽  
Laryngeal Cancer ◽  
Primary Tumour ◽  
Duodenal Mucosa ◽  
Cervical Lymph Nodes ◽  
Sagittal Sinus ◽  
Whole Brain Radiation ◽  
Positron Emission ◽  
Node Metastases ◽  
Clonic Seizures

A 60-year-old man was found unconscious at work, without any signs of trauma. At the site, he presented with tonic-clonic seizures, central facial palsy and eye deviation. A CT scan of the cerebrum did not find bleeding or thrombosis, but contrast enhancement at the superior sagittal sinus and pathological cervical lymph nodes. The MRI demonstrated multiple intracerebral metastases, while a supplementary fluoro-deoxy-glucose positron emission tomography scan revealed metastatic lesions above and below the diaphragm, without signs of a primary tumour. An ear, nose and throat examination found a small supraglottic tumour and cervical lymph node metastases. Following a multidisciplinary team discussion, biopsies from the duodenal mucosa and an inguinal lymph node were performed, showing squamous cell carcinoma with its origin in the head and neck. The patient was diagnosed with a T1N2cM1 supraglottic laryngeal cancer, receiving palliative whole brain radiation therapy but died 11 weeks after the debut of symptoms.

scholarly journals Superficial and deep lymph node dissection for stage III cutaneous melanoma: clinical outcome and prognostic factors

2013 ◽  
Vol 11 (1) ◽  
pp. 36 ◽  
Author(s):  
Nicola Mozzillo ◽  
Corrado Caracò ◽  
Ugo Marone ◽  
Gianluca Di Monta ◽  
Anna Crispo ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Lymph Node ◽  
Clinical Outcome ◽  
Lymph Node Dissection ◽  
Cutaneous Melanoma ◽  
Stage Iii ◽  
Node Dissection

scholarly journals Expression of ALDH1 in axillary lymph node metastases is a prognostic factor of poor clinical outcome in breast cancer patients with 1–3 lymph node metastases

Breast Cancer ◽  
2012 ◽  
Vol 21 (1) ◽  
pp. 58-65 ◽  
Author(s):  
Tomohiro Nogami ◽  
Tadahiko Shien ◽  
Takehiro Tanaka ◽  
Keiko Nishiyama ◽  
Taeko Mizoo ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Prognostic Factor ◽  
Clinical Outcome ◽  
Lymph Node Metastases ◽  
Axillary Lymph ◽  
Breast Cancer Patients ◽  
Poor Clinical Outcome ◽  
Axillary Lymph Node Metastases ◽  
Node Metastases

scholarly journals Completely resected stage III melanoma controversy - 15 years of national tertiary centre experience

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Barbara Peric ◽  
Sara Milicevic ◽  
Andraz Perhavec ◽  
Marko Hocevar ◽  
Janez Zgajnar
Keyword(s):  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Rapid Development ◽  
Primary Tumour ◽  
Stage Iii ◽  
Unknown Primary ◽  
Tertiary Centre ◽  
Kaplan Meier ◽  
Stage Iii Melanoma ◽  
Resected Stage

AbstractBackgroundTwo prospective randomized studies analysing cutaneous melanoma (CM) patients with sentinel lymph node (SLN) metastases and rapid development of systemic adjuvant therapy have changed our approach to stage III CM treatment. The aim of this study was to compare results of retrospective survival analysis of stage III CM patients’ treatment from Slovenian national CM register to leading international clinical guidelines.Patients and methodsSince 2000, all Slovenian CM patients with primary tumour ≥ TIb are treated at the Institute of Oncology Ljubljana and data are prospectively collected into a national CM registry. A retrospective analysis of 2426 sentinel lymph node (SLN) biopsies and 789 lymphadenectomies performed until 2015 was conducted using Kaplan-Meier survival curves and log-rank tests.ResultsPositive SLN was found in 519/2426 (21.4%) of patients and completion dissection (CLND) was performed in 455 patients. The 5-year overall survival (OS) of CLND group was 58% vs. 47% of metachronous metastases group (MLNM) (p = 0.003). The 5-year OS of patients with lymph node (LN) metastases and unknown primary site (UPM) was 45% vs. 21% of patients with synchronous LN metastasis. Patients with SLN tumour burden < 0.3 mm had 5-year OS similar to SLN negative patients (86% vs. 85%; p = 0.926). The 5-year OS of patients with burden > 1.0 mm was similar to the MLNM group (49% vs. 47%; p = 0.280).ConclusionsStage III melanoma patients is a heterogeneous group with significant OS differences. CLND after positive SLNB might still remain a method of treatment for selected patients with stage III.

Vascular endothelial growth factor-C and its receptor VEGFR-3 in non-small-cell lung cancer: Concurrent expression in cancer cells from primary tumour and metastatic lymph node

Lung Cancer ◽  
2007 ◽  
Vol 58 (2) ◽  
pp. 205-213 ◽  
Author(s):  
Pierre Saintigny ◽  
Marianne Kambouchner ◽  
Madani Ly ◽  
Noëlia Gomes ◽  
Odile Sainte-Catherine ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Vascular Endothelial Growth Factor ◽  
Lymph Node ◽  
Metastatic Lymph Node ◽  
Primary Tumour ◽  
Small Cell ◽  
Vascular Endothelial ◽  
Small Cell Lung ◽  
Factor C ◽  
Endothelial Growth Factor

scholarly journals Clinical Outcome of Retroperitoneal Lymph Node Dissection after Chemotherapy in Patients with Pure Embryonal Carcinoma in the Orchiectomy Specimen

Urology ◽  
2018 ◽  
Vol 114 ◽  
pp. 133-138 ◽  
Author(s):  
Catherine M. Dowling ◽  
Melissa Assel ◽  
John E. Musser ◽  
Joshua J. Meeks ◽  
Daniel D. Sjoberg ◽  
...  
Keyword(s):  
Lymph Node ◽  
Clinical Outcome ◽  
Lymph Node Dissection ◽  
Embryonal Carcinoma ◽  
Retroperitoneal Lymph Node Dissection ◽  
Node Dissection ◽  
Retroperitoneal Lymph Node
Sign in / Sign up

Export Citation Format

Share Document