Can microRNA‐96‐5p serve as a therapeutic molecule in the near future?

2022 ◽  
Vol 52 (1) ◽  
pp. 3-4
Author(s):  
Tsutomu Masaki ◽  
Joji Tani ◽  
Asahiro Morishita
Keyword(s):  
Near Future

Spectrophotometric reductions with an IBM 1620

1966 ◽  
Vol 24 ◽  
pp. 116-117
Author(s):  
P.-I. Eriksson
Keyword(s):  
Astronomical Data ◽  
Spectrophotometric Data ◽  
Electronic Computers ◽  
The University ◽  
Near Future

Nowadays more and more of the reductions of astronomical data are made with electronic computers. As we in Uppsala have an IBM 1620 at the University, we have taken it to our help with reductions of spectrophotometric data. Here I will briefly explain how we use it now and how we want to use it in the near future.

Recent developments in automated Transmission Electron MI

1989 ◽  
Vol 47 ◽  
pp. 46-47
Author(s):  
W.J. de Ruijter ◽  
P. Rez ◽  
David J. Smith
Keyword(s):  
Image Analysis ◽  
Computer Image ◽  
Lens Design ◽  
Computer Image Analysis ◽  
Transmission Electron ◽  
Resolution Electron ◽  
Recent Developments ◽  
On Line ◽  
Routine Procedures ◽  
Near Future

There is growing interest in the on-line use of computers in high-resolution electron n which should reduce the demands on highly skilled operators and thereby extend the r of the technique. An on-line computer could obviously perform routine procedures hand, or else facilitate automation of various restoration, reconstruction and enhan These techniques are slow and cumbersome at present because of the need for cai micrographs and off-line processing. In low resolution microscopy (most biologic; primary incentive for automation and computer image analysis is to create a instrument, with standard programmed procedures. In HREM (materials researc computer image analysis should lead to better utilization of the microscope. Instru (improved lens design and higher accelerating voltages) have improved the interpretab the level of atomic dimensions (approximately 1.6 Å) and instrumental resolutior should become feasible in the near future.

DNA methylation in satellite repeats disorders

2019 ◽  
Vol 63 (6) ◽  
pp. 757-771 ◽  
Author(s):  
Claire Francastel ◽  
Frédérique Magdinier
Keyword(s):  
Dna Methylation ◽  
Human Genome ◽  
Repetitive Dna ◽  
Dna Sequences ◽  
Satellite Repeats ◽  
Tremendous Progress ◽  
Genes Encoding ◽  
Dna Elements ◽  
Near Future

Abstract Despite the tremendous progress made in recent years in assembling the human genome, tandemly repeated DNA elements remain poorly characterized. These sequences account for the vast majority of methylated sites in the human genome and their methylated state is necessary for this repetitive DNA to function properly and to maintain genome integrity. Furthermore, recent advances highlight the emerging role of these sequences in regulating the functions of the human genome and its variability during evolution, among individuals, or in disease susceptibility. In addition, a number of inherited rare diseases are directly linked to the alteration of some of these repetitive DNA sequences, either through changes in the organization or size of the tandem repeat arrays or through mutations in genes encoding chromatin modifiers involved in the epigenetic regulation of these elements. Although largely overlooked so far in the functional annotation of the human genome, satellite elements play key roles in its architectural and topological organization. This includes functions as boundary elements delimitating functional domains or assembly of repressive nuclear compartments, with local or distal impact on gene expression. Thus, the consideration of satellite repeats organization and their associated epigenetic landmarks, including DNA methylation (DNAme), will become unavoidable in the near future to fully decipher human phenotypes and associated diseases.

Identification and Transformation of Terminal Morphemes in Medical English

1969 ◽  
Vol 8 (02) ◽  
pp. 84-90 ◽  
Author(s):  
A. W. Pratt ◽  
M. Pacak
Keyword(s):  
Word Form ◽  
Subsequent Transformation ◽  
Part Of Speech ◽  
Morphological Segmentation ◽  
Medical English ◽  
Nominal Form ◽  
Admissible Path ◽  
Near Future ◽  
The Given ◽  
Admissible Sequences

The system for the identification and subsequent transformation of terminal morphemes in medical English is a part of the information system for processing pathology data which was developed at the National Institutes of Health.The recognition and transformation of terminal morphemes is restricted to classes of adjectivals including the -ING and -ED forms, nominals and homographic adjective/noun forms.The adjective-to-noun and noun-to-noun transforms consist basically of a set of substitutions of adjectival and certain nominal suffixes by a set of suffixes which indicate the corresponding nominal form(s).The adjectival/nominal suffix has a polymorphosyntactic transformational function if it has the property of being transformed into more than one nominalizing suffix (e.g., the adjectival suffix -IC can be substituted by a set of nominalizing suffixes -Ø, -A, -E, -Y, -IS, -IA, -ICS): the adjectival suffix has a monomorphosyntactic transformational property if there is only one admissible transform (e.g., -CIC → -X).The morphological segmentation and the subsequent transformations are based on the following principles:a. The word form is segmented according to the principle of »double consonant cut,« i.e., terminal characters following the last set of double consonants are analyzed and treated as a potential suffix. For practical purposes only such terminal suffixes of a maximum length of four have been analyzed.b. The principle that the largest segment of a word form common to both adjective and noun or to both noun stems is retained as a word base for transformational operations, and the non-identical segment is considered to be a »suffix.«The backward right-to-left character search is initiated by the identification of the terminal grapheme of the given word form and is extended to certain admissible sequences of immediately preceding graphemes.The nodes which represent fixed sequences of graphemes are labeled according to their recognition and/or transformation properties.The tree nodes are divided into two groups:a. productive or activatedb. non-productive or non-activatedThe productive (activated) nodes are sequences of sets of graphemes which possess certain properties, such as the indication about part-of-speech class membership, the transformation properties, or both. The non-productive (non-activated) nodes have the function of connectors, i.e., they specify the admissible path to the productive nodes.The computer program for the identification and transformation of the terminal morphemes is open-ended and is already operational. It will be extended to other sub-fields of medicine in the near future.

MANAGEMENT OF THE SUCCESS OF STUDENT’S LEARNING BASED ON THE MARKOV MODEL

2018 ◽  
pp. 4-11
Author(s):  
M. V. Noskov ◽  
M. V. Somova ◽  
I. M. Fedotova
Keyword(s):  
Information System ◽  
Markov Process ◽  
Continuous Time ◽  
Information Technologies ◽  
Educational Process ◽  
Automated Information System ◽  
The Subject ◽  
The University ◽  
Independent Work ◽  
Near Future

The article proposes a model for forecasting the success of student’s learning. The model is a Markov process with continuous time, such as the process of “death and reproduction”. As the parameters of the process, the intensities of the processes of obtaining and assimilating information are offered, and the intensity of the process of assimilating information takes into account the attitude of the student to the subject being studied. As a result of applying the model, it is possible for each student to determine the probability of a given formation of ownership of the material being studied in the near future. Thus, in the presence of an automated information system of the university, the implementation of the model is an element of the decision support system by all participants in the educational process. The examples given in the article are the results of an experiment conducted at the Institute of Space and Information Technologies of Siberian Federal University under conditions of blended learning, that is, under conditions when classroom work is accompanied by independent work with electronic resources.

Syrian Crisis and Migration

2015 ◽  
Vol 12 (3) ◽  
pp. 181-192 ◽  
Author(s):  
Pinar Yazgan ◽  
Deniz Eroglu Utku ◽  
Ibrahim Sirkeci
Keyword(s):  
Human Mobility ◽  
Special Issue ◽  
Host Countries ◽  
Syrian Crisis ◽  
Mass Migration ◽  
Large Numbers ◽  
And Migration ◽  
Europe Today ◽  
The Impact ◽  
Near Future

With the growing insurrections in Syria in 2011, an exodus in large numbers have emerged. The turmoil and violence have caused mass migration to destinations both within the region and beyond. The current "refugee crisis" has escalated sharply and its impact is widening from neighbouring countries toward Europe. Today, the Syrian crisis is the major cause for an increase in displacement and the resultant dire humanitarian situation in the region. Since the conflict shows no signs of abating in the near future, there is a constant increase in the number of Syrians fleeing their homes. However, questions on the future impact of the Syrian crisis on the scope and scale of this human mobility are still to be answered. As the impact of the Syrian crisis on host countries increases, so does the demand for the analyses of the needs for development and protection in these countries. In this special issue, we aim to bring together a number of studies examining and discussing human mobility in relation to the Syrian crisis.

Demographic gaps between Syrian and the European populations: What do they suggest?

2017 ◽  
Vol 7 (2) ◽  
pp. 207-230 ◽  
Author(s):  
Mustafa Murat Yucesahin ◽  
Ibrahim Sirkeci
Keyword(s):  
Transition Theory ◽  
World Population ◽  
Demographic Analysis ◽  
Demographic Differences ◽  
Syrian Crisis ◽  
The United Kingdom ◽  
Syrian Population ◽  
Displaced People ◽  
Near Future

Syrian crisis resulted in at least 6.1 million externally displaced people 983,876 of whom are in Europe while the rest are in neighbouring countries in the region. Turkey, due to its geographical proximity and substantial land borders with the country, has been the most popular destination for those fleeing Syria since April 2011. Especially after 2012, a sharp increase in the number of Syrian refugees arriving in Turkey was witnessed. This has triggered an exponential growth in academic and public interest in Syrian population. Numerous reports mostly based on non-representative sample surveys have been disseminated whilst authoritative robust analyses remained absent. This study aims to fill this gap by offering a comprehensive demographic analysis of the Syrian population. We focus on the demographic differences (from 1950s to 2015) and demographic trends (from 2015 to 2100) in medium to long term, based on data from World Population Prospects (WPP). We offer a comparative picture to underline potential changes and convergences between populations in Syria, Turkey, Germany, and the United Kingdom. We frame our discussion here with reference to the demographic transition theory to help understanding the implications for movers and non-movers in receiving countries in the near future.

The Alliance between Fundamentalist Christians and the Pro-Israel Lobby: Christian Zionism in US Middle East Policy

2004 ◽  
Vol 2 (2) ◽  
pp. 163-187
Author(s):  
Donald E. Wagner
Keyword(s):  
Middle East ◽  
Political Influence ◽  
Conservative Movement ◽  
International Media ◽  
Christian Zionism ◽  
The Us ◽  
Run Up ◽  
Middle East Policy ◽  
Near Future ◽  
Political Scene

It is a common assumption in the international media that the fundamentalist Christian Right suddenly appeared on the US political scene following the 11 September 2001 tragedy, and that it became a major force in shaping US policy in the Middle East. While it is true that fundamentalist Christians have exercised considerable influence during the George W. Bush administration, their ascendance is neither new nor surprising. The movement has demonstrated political influence in the US and England intermittently for more than a hundred years, particularly in the formation of Middle East policy. This article focuses on the unique theology and historical development of Christian Zionism, noting its essential beliefs, its emergence in England during the nineteenth century, and how it grew to gain prominence in the US. The alliance of the pro-Israel lobby, the neo-conservative movement, and several Christian Zionist organizations in the US represents a formidable source of support for the more maximalist views of Israel's Likud Party. In the run-up to the 2004 US presidential elections this alliance could potentially thwart any progress on an Israeli–Palestinian peace plan in the near future. Moreover, Likud ideology is increasingly evident in US Middle East policy as a result of this alliance.

CONVERTING THE VEHICLE BY REPLACING THE INTERNAL COMBUSTION ENGINE

2019 ◽  
pp. 29-35
Author(s):  
Oleksandr Gryshchuk ◽  
Volodymyr Hladchenko ◽  
Uriy Overchenko
Keyword(s):  
Internal Combustion Engine ◽  
Electric Vehicle ◽  
Electric Motor ◽  
Combustion Engine ◽  
Internal Combustion ◽  
Environmental Safety ◽  
Environmental Conservation ◽  
Sales Forecasts ◽  
Financial Investments ◽  
Near Future

This article looks at some comparative statistics on the development and use of electric vehicles (hereinafter referred to as EM) as an example of sales and future sales forecasts for EM in countries that focus on environmental conservation. Examples of financial investments already underway and to be made in the near future by the largest automakers in the development and distribution of EM in the world are given. Steps are taken to improve the environmental situation in countries (for example, the prohibition of entry into the city center), the scientific and applied problem of improving the energy efficiency and environmental safety of the operation of wheeled vehicles (hereinafter referred to as the CTE). The basic and more widespread schemes of conversion of the internal combustion engine car (hereinafter -ICE) to the electric motor car (by replacing the gasoline or diesel electric motor), as well as the main requirements that must be observed for the safe use and operation of the electric vehicle. The problem is solved by justifying the feasibility of re-equipment of the KTZ by replacing the internal combustion engine with an electric motor. On the basis of the statistics collected by the State Automobile Transit Research Institute on the number of issued conclusions of scientific and technical expertise regarding the approval of the possibility of conversion of a car with an internal combustion engine (gasoline or diesel) to a car with an electric motor (electric vehicle), the conclusions on the feasibility of such conclusion were made. Keywords: electricvehicles, ecological safety, electricmotor, statistics provided, car, vehicle by replacing.

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