Abstract
Objective: The objective of this study was to investigate associations between Energy-Adjusted Dietary Inflammatory Index (EDII) with quality of life and serum inflammatory markers.Results: This cross-sectional study was performed on 280 adult healthy overweigh and obese aged between 18 and 50 years old that was selected from 20 various health centers by a multistage cluster random sampling method. The mean age of the study participants was 36.30±8.05 years. Analyses were performed using multivariable linear regression, adjusting for age, weight, physical activity, smoking status, economic status, and employment status. Linear regression analysis demonstrated that E-DII were significantly associated with certain the quality of life criteria, such as physical function, mental health, and vitality (β = 5.58, 95% CI 0.72, 10.43, p = 0.024, β = 16.88, 95% CI 10.75, 23, p < 0.0001 and β = 14.29, 95% CI 9.48, 20.36, p < 0.0001, respectively). No significant associations were observed between EDII and serum level hs-CRP. It was found that dietary inflammatory potential decreased some quality of life measurements and levels in overweight and obese Iranian women.