The relationship between impaired fasting glucose and self-reported sleep quality in a Chinese population

2013 ◽  
Vol 78 (4) ◽  
pp. 518-524 ◽  
Author(s):  
Hao-Chang Hung ◽  
Yi-Ching Yang ◽  
Horng-Yih Ou ◽  
Jin-Shang Wu ◽  
Feng-Hwa Lu ◽  
...  
Nutrients ◽  
2018 ◽  
Vol 10 (10) ◽  
pp. 1359 ◽  
Author(s):  
Lukasz Szternel ◽  
Magdalena Krintus ◽  
Katarzyna Bergmann ◽  
Tadeusz Derezinski ◽  
Grazyna Sypniewska

Background: The aim of this study was to assess the relationship between vitamin D status and the prevalence of dyslipidemia and impaired fasting glucose (IFG) in children. Methods and Summary: 284 children (150 boys and 134 girls) aged 9–11 were included in the study. Children with deficient 25(OH)D (25-hydroxycholecalciferol) levels ≤20 ng/mL (50 nmol/L) were characterized by a more frequent occurrence of impaired fasting glucose (IFG) (Odd ratios (OR) = 1.966, 95% confidence interval (CI): 1.055–3.663; p = 0.033) when compared to children with 25(OH)D >20 ng/mL. Serum 25(OH)D with concentration lower by 1 ng/mL (2.5 nmol/L) was linked to higher fasting glucose (by 0.25 mg/dL, 0.013 mmol/L; p = 0.017), higher total cholesterol (TC) by almost 1 mg/dL (0.96 mg/dL, 0.25 mmol/L; p = 0.006) and higher high-density lipoprotein cholesterol (HDL-C) (by 0.57 mg/dL, 0.015 mmol/L; p < 0.001). Conclusion: 25(OH)D deficiency may negatively affect fasting glucose and total cholesterol concentration in children aged 9–11. Vitamin D-deficient children are twice as likely to develop prediabetes as reflected by impaired fasting glucose when compared to those with a 25(OH)D level above 20 ng/mL (50 nmol/L).


BMJ Open ◽  
2014 ◽  
Vol 4 (3) ◽  
pp. e004436 ◽  
Author(s):  
Peian Lou ◽  
Peipei Chen ◽  
Lei Zhang ◽  
Pan Zhang ◽  
Guiqiu Chang ◽  
...  

BMJ Open ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. e042066
Author(s):  
Qingyun Lu ◽  
Shangxi Wu ◽  
Shiyu Wang ◽  
Jing Xiao

ObjectivesSystematic evaluation of the influence of occupation type on the association between sleep–glucose metabolismDesignA cross-sectional study.SettingThe Nantong Metabolic Syndrome Study is a Chinese population-based study.Participants20 502 participants aged 18–74 years old.InterventionNo intervention.Primary and secondary outcome measuresImpaired fasting glucose (IFG).ResultsA total of 1503 participants (7.33%) with a slightly longer sleep duration had IFG. After being stratified according to occupation, a sleep duration of ≥10 hours daily corresponded to a 1.321-fold risk of IFG (95% CI 1.071 to 1.628, p=0.0092) among moderate and heavy physical workers compared with those with a daily sleep duration of 7–9 hours. There was no significant relationship between sleep and IFG among other types of workers. Moreover, we discovered a gender difference in the influence of occupation on the sleep–IFG. A positive association among moderate and heavy physical men and a negative association among light or sedentary men were established, but not in unemployed men. However, a positive association was evident only in unemployed women; there was no significant association among other occupations.ConclusionThis study highlights the role of occupation in the relationship of sleep–glucose metabolism. A gender difference was found to have been influenced by occupational types on the sleep–metabolic association.


2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Sae Aoyama-Sasabe ◽  
Mitsuo Fukushima ◽  
Xin Xin ◽  
Ataru Taniguchi ◽  
Yoshikatsu Nakai ◽  
...  

Objective.To investigate the characteristics of isolated impaired glucose tolerance (IGT) and isolated impaired fasting glucose (IFG), we analyzed the factors responsible for elevation of 2-hour postchallenge plasma glucose (2 h PG) and fasting plasma glucose (FPG) levels.Methods.We investigated the relationship between 2 h PG and FPG levels who underwent 75 g OGTT in 5620 Japanese subjects at initial examination for medical check-up. We compared clinical characteristics between isolated IGT and isolated IFG and analyzed the relationships of 2 h PG and FPG with clinical characteristics, the indices of insulin secretory capacity, and insulin sensitivity.Results.In a comparison between isolated IGT and isolated IFG, insulinogenic index was lower in isolated IGT than that of isolated IFG (0.43 ± 0.34 versus 0.50 ± 0.47, resp.;p<0.01). ISI composite was lower in isolated IFG than that of isolated IGT (6.87 ± 3.38 versus 7.98 ± 4.03, resp.;p<0.0001). In isolated IGT group, insulinogenic index showed a significant correlation with 2 h PG (r=-0.245,p<0.0001) and had the strongest correlation with 2 h PG (β=-0.290). In isolated IFG group, ISI composite showed a significant correlation with FPG (r=-0.162,p<0.0001) and had the strongest correlation with FPG (β=-0.214).Conclusions.We have elucidated that decreased early-phase insulin secretion is the most important factor responsible for elevation of 2 h PG levels in isolated IGT subjects, and decreased insulin sensitivity is the most important factor responsible for elevation of FPG levels in isolated IFG subjects.


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