Inflammation and wound healing in cats with chronic gingivitis/stomatitis after extraction of all premolars and molars were not affected by feeding of two diets with different omega-6/omega-3 polyunsaturated fatty acid ratios

2011 ◽  
Vol 96 (4) ◽  
pp. 671-680 ◽  
Author(s):  
R. J. Corbee ◽  
H. E. Booij-Vrieling ◽  
C. H. A. van de Lest ◽  
L. C. Penning ◽  
M. A. Tryfonidou ◽  
...  
2021 ◽  
Vol 24 (1) ◽  
pp. 122-130
Author(s):  
M Lamudin Noor ◽  
Andarini Diharmi ◽  
Rahman Karnila

Minyak ikan patin mengandung kadar asam lemak omega-9, tetapi rendah asam lemak omega 3 Minyak hati ikan hiu memiliki kandungan asam lemak omega 3 relatif tinggi. Penelitian ini bertujuan untuk menentukan karakteristik dan sifat kimia minyak ikan patin dan profil asam lemak kombinasi minyak ikan patin dengan hati kan hiu. Metode penelitian eksperimen dengan melakukan ekstraksi lemak perut ikan patin secara dry rendering dihasilkan minyak kasar dan dimurnikan. Minyak ikan patin murni dilakukan pencampuran dengan minyak hati ikan hiu. dengan perbandingan 1:1, 2:1 dan 2:1. Parameter analisis terdiri atas karakteristik kimia (bilangan asam lemak bebas (ALB),bilangan  asam, peroksida, iod,  p-anisidin, penyabunan, total oksida/totox), dan profil asam lemak. Hasil penelitian menunjukkan bahwa kombinasi  minyak patin dan hati ikan hiu dihasilkan karakteristik kimia terdiri atas asam lemak bebas sebesar 1,59-2,19%, bilangan asam 2,86-3,00 mg KOH/g, peroksida 15,50-18,32 meq/kg, iod 63,46-84,42 gI2/100g), p-anisidin 21,53-24,16, penyabunan 142,21-162,28 mg KOH/g dan TOTOX 53,33-69,43. Hasil analisis komposisi asam lemak jenuh (saturated fatty acid/SAFA) dihasilkan  asam palmitat tertinggi,  asam lemak tak jenuh tunggal  (mono unsaturated fatty acid/MUFA)  asam oleat,  dan asam lemak tak jenuh ganda (polyunsaturated fatty acid/PUFA)  asam linoleat. Hasil analisis karakteristik kimia kombinasi  minyak ikan patin dan hati ikan hiu sesuai dengan standar IFOMA. Kombinasi minyak hati ikan hiu dan ikan patin dengan perbandingan (2:1) dihasilkan kandungan omega 3 dan omega 6 sebesar 2,59 % dan 29,75%.


2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Sara Huerta-Yepez ◽  
Ana Tirado-Rodriguez ◽  
Mayra R. Montecillo-Aguado ◽  
Jun Yang ◽  
Bruce D. Hammock ◽  
...  

1997 ◽  
Vol 89 (15) ◽  
pp. 1123-1131 ◽  
Author(s):  
D. Bagga ◽  
S. Capone ◽  
H.-J. Wang ◽  
D. Heber ◽  
M. Lill ◽  
...  

Marine Drugs ◽  
2021 ◽  
Vol 19 (12) ◽  
pp. 692
Author(s):  
Hiroki Muramatsu ◽  
Naoe Akimoto ◽  
Michio Hashimoto ◽  
Kenji Sugibayashi ◽  
Masanori Katakura

Arachidonic acid (ARA), an omega-6 (ω-6) polyunsaturated fatty acid (PUFA), is involved in the development and maintenance of renal functions, whereas docosahexaenoic acid (DHA) is an omega-3 (ω-3) PUFA that has anti-inflammatory effects and attenuates nephropathy. However, their effects on the progression of chronic kidney disease (CKD) remain unknown. The aim of this study was to assess the effects of feeding ARA, DHA, and ARA and DHA-containing diets on rats with 5/6 nephrectomized kidneys. Urine and feces were collected every 4 weeks, and the kidneys were collected at 16 weeks after surgery. Urinary albumin (U-ALB) excretion increased gradually with nephrectomy, but the U-ALB excretion was attenuated by feeding the rats with an ARA + DHA-containing diet. Reactive oxygen species (ROS) levels in the kidneys were lower in the ARA + DHA group than in the other groups. At 4 weeks after surgery, the lipid peroxide (LPO) levels in the plasma of the ARA + DHA groups decreased significantly after surgery compared to the control CKD group, but this did not happen at 16 weeks post-surgery. There was a significant negative correlation between LPO levels in the plasma at 4 weeks and creatinine clearance, and a positive correlation with urinary albumin levels. These results suggest that the combination of ARA and DHA inhibit the progress of early stage CKD.


2015 ◽  
Vol 49 (1) ◽  
Author(s):  
Dominika Vrbnjak ◽  
Majda Pajnkihar ◽  
Tomaž Langerholc

Uvod: Namen članka je prikazati analizo podatkov o učinkih maščobnih kislin omega-3 na celjenje ran ter njihovo uporabnost pri obravnavi ran na koži. Metode: Za pregled literature ter analizo dobljenih virov so bile uporabljene podatkovne baze: PubMed, CINAHL, Medline in ScienceDirect. Iskanje je bilo izvedeno s ključnimi besedami v angleščini: omega-3, fish oil, polyunsaturated fatty acid (PUFA), wound, wound healing, in Boolovim operatorjem AND. V analizo so bile vključene eksperimentalne ali randomizirane klinične raziskave, objavljene v angleškem jeziku in izdane od 1993 do januarja 2014, ki so vključevale preprečevanje ali zdravljenje akutnih ali kroničnih ran na koži z uporabo maščobnih kislin omega-3. Izključitveni kriterij je bil obravnava uporabe maščobnih kislin omega-3 pri opeklinah. Iz iskalnega nabora 1151 zadetkov je bilo v podrobno analizo vključenih 15 raziskav. Rezultati: Rezultati analize literature so pokazali, da so maščobne kisline omega-3 večinoma neučinkovite pri obravnavi travmatskih in kirurških ran na koži, potencialno učinkovite pri obravnavi diabetičnih ran in učinkovite pri obravnavi razjed zaradi pritiska. Diskusija in zaključek: Protivnetni učinek maščobnih kislin omega-3 upočasnjuje in moti celjenje akutnih ran na koži, vendar lahko z njimi obvladujemo lokalne vnetne odzive in pospešujemo reepitelizacijo pri kroničnih ranah. Za oblikovanje natančnih smernic uporabe bodo potrebna nadaljnja raziskovanja.


Lupus ◽  
2020 ◽  
Vol 29 (6) ◽  
pp. 554-559 ◽  
Author(s):  
Stefan Vordenbäumen ◽  
Alexander Sokolowski ◽  
Laura Kutzner ◽  
Katharina M Rund ◽  
Christina Düsing ◽  
...  

Objective This study aimed to assess polyunsaturated fatty acid (PUFA) status and association with systemic inflammation and fish consumption in systemic lupus erythematosus (SLE). Methods Parameters of PUFA status including the proportion of omega-6 and -3 fatty acids in highly unsaturated fatty acids (omega-6%, omega-3%), essential fatty acids linoleic acid (LA) and alpha-linolenic acid (ALA), the omega-6 PUFA arachidonic acid (ARA) and the sum of key omega-3 PUFA eicosapentaenoic acid+docosahexaenoic acid (omega-3 status) were measured by gas chromatography in 68 SLE patients (88.2% female, aged 45.7±12.5 years). Associations with serum CRP, disease activity, damage and fish consumption were assessed by linear regression modelling adjusted for age, sex and body mass index. Associations are reported in terms of regression coefficients (β). Results Omega-6 PUFA were associated with higher CRP: omega-6% (β = 0.052, p = 0.02), the ratio of LA/ALA (β = 0.007, p = 0.02) and ARA (β = 0.308, p = 0.001). Conversely, omega-3% was associated with lower CRP (β = −0.051, p = 0.02). Increased dietary PUFA consumption from fish (g/day) was linked to a higher omega-3 status (β = 2.21, p = 0.02) and lower self-reported damage (Brief Index of Lupus Damage; β = −3.22, p = 0.02). Conclusions Omega-3 and omega-6 fatty acid status differentially reflect systemic inflammation in SLE and are linked to fish consumption.


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