The impact of anatomical location and sun exposure on the dermoscopic recognition of atypical nevi and early melanomas: usefulness of an integrated clinical‐dermoscopic method ( iDScore )

2020 ◽  
Author(s):  
L. Tognetti ◽  
A. Cartocci ◽  
E. Cinotti ◽  
E. Moscarella ◽  
F. Farnetani ◽  
...  
Keyword(s):  
Sun Exposure ◽  
Anatomical Location ◽  
The Impact ◽  
Atypical Nevi

A descriptive study of stress fractures in competitive event horses in the UK

2004 ◽  
Vol 1 (4) ◽  
pp. 233-238
Author(s):  
Emma Hayton ◽  
Jennifer C Sneddon
Keyword(s):  
Stress Fracture ◽  
Descriptive Study ◽  
Stress Fractures ◽  
Anatomical Location ◽  
True Prevalence ◽  
Fracture Prevalence ◽  
The Uk ◽  
The Impact ◽  
Larger Sample ◽  
Age Category

AbstractThe impact of stress fractures on competitive event horses in the UK is completely unknown. Ninety-one replies to 450 questionnaires sent to competitive event riders across the UK indicated that 11 horses, representing 12% of the responders, had a confirmed stress fracture. As data on the total number of horses owned or ridden by the riders were not available, the true prevalence of stress fractures in this sample of horses could not be directly assessed. Within the bounds of this study, competitive level of the rider had a significant effect on stress fracture prevalence (X2(0.05, df. 2) = 24.74, P<0.05), as did years of eventing experience (X2(0.05, df. 1) = 27.80, P<0.01). Training regime was also influential (X2(0.05,df. 1) = 26.30, PX20.01). There was a predominance of fractures in geldings (X2(0.05, df. 1) = 24.45, P<0.03); however, geldings constituted 82% of reported cases. Thoroughbred cross horses had a significantly lower incidence of stress fractures than Thoroughbreds (X2(0.05, df. 1) = 20.82, P<0.01) but constituted only 18% of the sample. Horses in the oldest age category (9–12 years) had 6% of all stress fractures (X2(0.05, df. 2) = 24.54, P<0.1). All fractures occurred on the foreleg at the knee or below, with no significant effect of anatomical location. Seventy-three per cent of horses were not competing when diagnosed (X2(0.05, df. 1) = 22.27, P<0.1). These data indicate that useful preliminary data were yielded by the questionnaire and that further research with a larger sample size is justified.

scholarly journals Analysis of Office Rooms Energy Consumption Data in Respect to Meteorological and Direct Sun Exposure Conditions

Energies ◽  
2021 ◽  
Vol 14 (22) ◽  
pp. 7590
Author(s):  
Adam Kula ◽  
Albert Smalcerz ◽  
Maciej Sajkowski ◽  
Zygmunt Kamiński
Keyword(s):  
Energy Consumption ◽  
Public Service ◽  
Residential Buildings ◽  
Sun Exposure ◽  
Building Energy ◽  
The West ◽  
Building Energy Management ◽  
Consumption Data ◽  
Office Rooms ◽  
The Impact

There are many papers concerning the consumption of energy in different buildings. Most describe residential buildings, with only a few about office- or public service buildings. Few articles showcase the use of energy consumption in specific rooms of a building, directed in different geographical directions. On the other hand, many publications present methods, such as machine learning or AI, for building energy management and prediction of its consumption. These methods have limitations and represent a certain level of uncertainty. In order to compare energy consumption of different rooms, the measurements of particular building-room parameters were collected and analyzed. The obtained results showcase the effect of room location, regarding geographical directions, for the consumption of energy for heating. For south-exposed rooms, due to sun radiation, it is possible to switch heating off completely, and even overheating of 3 °C above the 22 °C temperature set point occurs. The impact of the sun radiation for rooms with a window directed east or west reached about 1 °C and lasts for a few hours before noon for the east, and until late afternoon for the west.

scholarly journals College Students’ Perceptions of Worry and Parent Beliefs: Associations with Behaviors to Prevent Sun Exposure

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Robert A. Yockey ◽  
Laura A. Nabors ◽  
Oladunni Oluwoye ◽  
Kristen Welker ◽  
Angelica M. Hardee
Keyword(s):  
College Students ◽  
Protective Clothing ◽  
Sun Exposure ◽  
Sun Protection ◽  
Parental Beliefs ◽  
Parent Beliefs ◽  
Prevention Messages ◽  
Midwestern University ◽  
History Of ◽  
The Impact

More research is needed to understand how attitudes impact behaviors that afford sun protection. The current study examined the impact of students’ perceptions of parental beliefs about sun exposure and its influence on their practiced sun protection behaviors and worry about sun exposure. Participants were college students (N=462) at a large Midwestern university. They completed a survey to examine their perceptions of risks and messages about sun exposure and sun exposure behaviors. Results indicated that gender and students’ perceptions of parental beliefs about sun exposure were related to sun protection behaviors and their own worry over sun exposure. Specifically, males showed lower levels of sun protection behaviors, with the exception of wearing a hat with a brim, and lower levels of worry about sun exposure compared to females. Roughly a third of our sample had a family history of skin cancer, and this variable was related to worry about sun exposure and parental beliefs. Prevention messages and interventions to reduce sun risk for college students should address risks of sun exposure as well as educating young adults about the importance of wearing sunscreen, protective clothing, and hats to improve sun protection.

Critical windows in development of the rodent immune system

2002 ◽  
Vol 21 (9-10) ◽  
pp. 493-498 ◽  
Author(s):  
K S Landreth
Keyword(s):  
Stem Cells ◽  
Immune System ◽  
Chemical Exposure ◽  
Anatomical Location ◽  
Hematopoietic Stem ◽  
Windows Of Vulnerability ◽  
The Impact ◽  
Timing Of Exposure ◽  
Developmental Immunotoxicity ◽  
Developmental Windows

The immune system of rodents, like that in humans, develops from a population of pluripotential hematopoietic stem cells (HSC) that are generated early in gestation from uncommitted mesenchymal stem cells in the intra-embryonic splanchnoplure surrounding the heart. This early population of HSC gives rise to all circulating blood cell lineages, including cells of the innate and acquired immune system. To access the impact of chemical exposure on the developing immune system and establish developmental windows of potential vulnerability to these exposures, it is essential to first consider the anatomical development of hematopoietic and lymphopoietic tissues and the sequence of appearance of cells that give rise to the immune system. This is particularly true in embryonic development because, after they initially appear in intra-embryonic mesenchyme early in gestation, HSC migrate through an orderly series of tissues before establishing residence in the bone marrow and thymus. The effect of exposure to chemical insults in utero, then, may differ depending on the specific timing of exposure and anatomical location of hematopoiesis. Mechanisms and consequences of developmental immunotoxicity in experimental animals will need to be considered in that context. This review presents an overview of developmental hematopoiesis and a working hypothesis of critical developmental windows of vulnerability of this developmental system to toxic insult by chemical exposure.

scholarly journals Comparison of epidemiology, treatments, and outcomes in pediatric versus adult ependymoma

2020 ◽  
Vol 2 (1) ◽  
Author(s):  
Aladine A Elsamadicy ◽  
Andrew B Koo ◽  
Wyatt B David ◽  
Victor Lee ◽  
Cheryl K Zogg ◽  
...  
Keyword(s):  
Older Adults ◽  
Young Adults ◽  
Radiation Treatment ◽  
Age Groups ◽  
Anatomical Location ◽  
Seer Database ◽  
Coding System ◽  
Significant Difference ◽  
All Cause Mortality ◽  
The Impact

Abstract Background Mounting evidence supports the presence of heterogeneity in the presentation of ependymoma patients with respect to location, histopathology, and behavior between pediatric and adult patients. However, the influence of age on treatment outcomes in ependymoma remains obscure. Methods The SEER database years 1975–2016 were queried. Patients with a diagnosis of ependymoma were identified using the International Classification of Diseases for Oncology, Third Edition, coding system. Patients were classified into one of 4 age groups: children (age 0–12 years), adolescents (age 13–21 years), young adults (age 22–45 years), and older adults (age &gt;45 years). The weighed multivariate analysis assessed the impact of age on survival outcomes following surgical treatment. Results There were a total of 6076 patients identified with ependymoma, of which 1111 (18%) were children, 529 (9%) were adolescents, 2039 (34%) were young adults, and 2397 (40%) were older adults. There were statistically significant differences between cohorts with respect to race (P &lt; .001), anatomical location (P &lt; .001), extent of resection (P &lt; .001), radiation use (P &lt; .001), tumor grade (P &lt; .001), histological classification (P &lt; .001), and all-cause mortality (P &lt; .001). There was no significant difference between cohorts with respect to gender (P = .103). On multivariate logistic regression, factors associated with all-cause mortality rates included males (vs females), supratentorial location (vs spinal cord tumors), and radiation treatment (vs no radiation). Conclusions Our study using the SEER database demonstrates the various demographic and treatment risk factors that are associated with increased rates of all-cause mortality between the pediatric and adult populations following a diagnosis of ependymoma.

342 The impact of IFNα2β on signaling of STAT1, STAT3, STAT5a, STAT5b, and SOCS3 in clinical melanoma precursors, the atypical NEVI

Cytokine ◽  
2008 ◽  
Vol 43 (3) ◽  
pp. 324
Author(s):  
Wenjun Wang ◽  
Ling Chen ◽  
Arash Radfar ◽  
John M. Kirkwood
Keyword(s):  
The Impact ◽  
Atypical Nevi

Variations in serum vitamin D status during cancer chemotherapy.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. e19550-e19550
Author(s):  
Bogda Koczwara ◽  
Richard John Woodman ◽  
Laisa Vicki Teleni ◽  
Michael Kimlin ◽  
Euan Thomas Walpole ◽  
...  
Keyword(s):  
Vitamin D ◽  
Demographic Data ◽  
Serum Vitamin ◽  
Sun Exposure ◽  
Unknown Primary ◽  
Curative Intent ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
The Impact ◽  
Low Serum

e19550 Background: Low serum vitamin D in cancer patients has been associated with inferior cancer outcomes and bone loss. The impact of chemotherapy on vitamin D levels is not known. We examined serum vitamin D levels during chemotherapy to identify magnitude and predictors of change. Methods: A prospective study of chemotherapy naïve patients commencing chemotherapy in two different sun exposure areas. Vitamin D (25(OH)D) deficiency was defined as ≤25 nmol/L and insufficiency 26-50 nmol/L. Demographic data, nutrition, sun exposure, season and biochemical parameters were collected at baseline 6 weeks (6W) and 12 weeks (12W) since commencement of treatment. The effects were assessed using a multivariate multilevel linear regression model that also included age, gender and BMI. Results: 82 Caucasian and 3 indigenous patients were enrolled. Median age was 57 (21-85) years. Forty-nine (58%) were female; 54 (65%) were treated with curative intent. Tumours included 29 (34%) breast,12 (14%) colorectal, 9 (11%) lymphomas, 7 (8%) leukemias, 7 (8%) lung, 5 (6%) ovarian, 3 (4%) testis, 3 (4%) unknown primary and 10 (11%) others. Median weight was 75 kg (50-151) and median BMI was 26.9 kg/m2 (17.7- 44.5). Seventy-six (89%) and 55 (65%) patients were receiving chemotherapy treatment at 6W and 12W respectively. Mean (±SD) serum 25(OH)D at baseline was 49.2±22.3 nmol/L. Ten (12%) patients were vitamin D deficient at baseline and a further 33 (41%) had insufficient levels. Mean serum 25(OH)D status was higher in higher sun exposure locations (61.9±22.1 nmol/L vs 42.2±19.2 nmol/L, p<0.001), varied according to season (spring=46.9±20.3 nmol/L, summer=50.8±18.2 nmol/L, fall=76.4±25.2 nmol/L, winter=36.5±15.7 nmol/L, p<0.001) and changed with treatment period (baseline=49.2±22.3 nmol/L, 6W=40.9±19.0 nmol/L, 12W=45.9±19.7 nmol/L, p=0.002). There was no association between 25(OH)D status and age, gender, BMI or nutritional status. Conclusions: Chemotherapy is associated with a fall in serum 25(OH)D. Further research is needed to determine the underlying mechanism, the impact of low serum 25(OH)D on patient outcomes and the potential role for screening and vitamin D supplementation in this group.

scholarly journals The Influence of Painful Sunburns and Lifetime Sun Exposure on the Risk of Actinic Keratoses, Seborrheic Warts, Melanocytic Nevi, Atypical Nevi, and Skin Cancer

2003 ◽  
Vol 120 (6) ◽  
pp. 1087-1093 ◽  
Author(s):  
Cornelis Kennedy ◽  
Rein Willemze ◽  
Frank R. de Gruijl ◽  
Jan N. Bouwes Bavinck ◽  
Chris D. Bajdik
Keyword(s):  
Skin Cancer ◽  
Sun Exposure ◽  
Actinic Keratoses ◽  
Melanocytic Nevi ◽  
Atypical Nevi
Sign in / Sign up

Export Citation Format

Share Document