Salvianolic acid B regulates collagen synthesis: Indirect influence on human dermal fibroblasts through the microvascular endothelial cell pathway

2021 ◽  
Author(s):  
Hong Meng ◽  
Meng‐Meng Zhao ◽  
Ru‐Ya Yang ◽  
Xiao‐Feng Deng ◽  
Hong‐Yan Zhang ◽  
...  
Keyword(s):  
Endothelial Cell ◽  
Collagen Synthesis ◽  
Dermal Fibroblasts ◽  
Salvianolic Acid B ◽  
Microvascular Endothelial Cell ◽  
Human Dermal Fibroblasts ◽  
Salvianolic Acid ◽  
Indirect Influence ◽  
Microvascular Endothelial

CircAMD1 regulates proliferation and collagen synthesis via sponging miR-27a-3p in P63-mutant human dermal fibroblasts

2021 ◽  
Author(s):  
Pengjun Su ◽  
Qi Qiao ◽  
Gengfeng Ji ◽  
Zhibo Zhang
Keyword(s):  
Collagen Synthesis ◽  
Dermal Fibroblasts ◽  
Human Dermal Fibroblasts

scholarly journals Differentiation of human pluripotent stem cells to brain microvascular endothelial cell-like cells suitable to study immune cell interactions

2021 ◽  
Vol 2 (2) ◽  
pp. 100563
Author(s):  
Hideaki Nishihara ◽  
Benjamin D. Gastfriend ◽  
Pelin Kasap ◽  
Sean P. Palecek ◽  
Eric V. Shusta ◽  
...  
Keyword(s):  
Stem Cells ◽  
Endothelial Cell ◽  
Pluripotent Stem Cells ◽  
Immune Cell ◽  
Human Pluripotent Stem Cells ◽  
Cell Interactions ◽  
Microvascular Endothelial Cell ◽  
Brain Microvascular Endothelial Cell ◽  
Microvascular Endothelial

A Porcine Model for Adipose Tissue-Derived Endothelial Cell Transplantation

1992 ◽  
Vol 1 (4) ◽  
pp. 293-298 ◽  
Author(s):  
Carlton Young ◽  
Bruce E. Jarrell ◽  
James B. Hoying ◽  
Stuart K. Williams
Keyword(s):  
Endothelial Cells ◽  
Adipose Tissue ◽  
Endothelial Cell ◽  
Cell Transplantation ◽  
Animal Studies ◽  
Porcine Model ◽  
Cell Isolation ◽  
Microvascular Endothelial Cell ◽  
Microvascular Endothelium ◽  
Microvascular Endothelial

The transplantation of endothelial cells represents a technology which has been suggested for applications ranging from improvement in function of implanted vascular devices to genetic therapy. The use of microvascular endothelial cell transplantation has seen increased use both in animal studies as well as clinical use. This report describes our techniques for the isolation and establishment of initial cultures of microvascular endothelial cells derived from porcine fat. A variety of anatomic sites within the pig were evaluated to determine the appropriateness of different sources of fat for endothelial cell isolation. The properitoneal fat was determined to be optimal due to the predominance of endothelium in this tissue and the ease of isolation of microvascular endothelium following collagenase digestion. The study of endothelial cell transplantation in the porcine model is now possible using the methods described for adipose tissue-derived micro vessel endothelial cell isolation.

Structural and functional characteristics of lung macro- and microvascular endothelial cell phenotypes

2004 ◽  
Vol 67 (2) ◽  
pp. 139-151 ◽  
Author(s):  
Judy King ◽  
Tray Hamil ◽  
Judy Creighton ◽  
Songwei Wu ◽  
Priya Bhat ◽  
...  
Keyword(s):  
Endothelial Cell ◽  
Microvascular Endothelial Cell ◽  
Functional Characteristics ◽  
Microvascular Endothelial ◽  
Cell Phenotypes

Endothelin-1 production by a microvascular endothelial cell line treated with Plasmodium falciparum parasitized red blood cells

2002 ◽  
Vol 103 (s2002) ◽  
pp. 464S-466S ◽  
Author(s):  
Nicoletta BASILICO ◽  
Livianna SPECIALE ◽  
Silvia PARAPINI ◽  
Pasquale FERRANTE ◽  
Donatella TARAMELLI
Keyword(s):  
Plasmodium Falciparum ◽  
Endothelial Cell ◽  
Red Blood Cells ◽  
Cell Line ◽  
Blood Cells ◽  
Microvascular Endothelial Cell ◽  
Microvascular Endothelium ◽  
Endothelial Cell Line ◽  
Endothelin 1 ◽  
Microvascular Endothelial

In this study, we investigated the production of endothelin 1 (ET-1) by a human microvascular endothelial cell line, HMEC-1, co-cultured with Plasmodium falciparum-parasitized red blood cells (pRBCs). The results indicate that hypoxia increased the basal level of ET-1 production by HMEC-1 cells after 24 or 48h of treatment. However, the co-incubation of HMEC-1 cells with pRBCs, but not with uninfected RBCs, induced a dose-dependent decrease of both constitutive and hypoxia-induced ET-1 production. The inhibition was not due to a decrease in cell viability, as lactate dehydrogenase release remained constant. These results indicate that pRBCs are able to interfere with both the constitutive and stimulated ET-1 release from the microvascular endothelium, thus inducing local modifications of the vascular tone and of the inflammatory response. This could be of relevance in the pathogenesis of the most severe forms of P. falciparum infections, such as cerebral malaria or malaria during pregnancy.

scholarly journals TWEAK/Fn14 pathway modulates properties of a human microvascular endothelial cell model of blood brain barrier

2013 ◽  
Vol 10 (1) ◽  
Author(s):  
Delphine Stephan ◽  
Oualid Sbai ◽  
Jing Wen ◽  
Pierre-Olivier Couraud ◽  
Chaim Putterman ◽  
...  
Keyword(s):  
Endothelial Cell ◽  
Blood Brain Barrier ◽  
Cell Model ◽  
Brain Barrier ◽  
Microvascular Endothelial Cell ◽  
Human Microvascular Endothelial Cell ◽  
Blood Brain ◽  
Microvascular Endothelial
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