Consumer profiling techniques for cosmetic formulation definition

2020 ◽  
Vol 35 (2) ◽  
Author(s):  
Vaniele B. Martins ◽  
Jéssica Bordim ◽  
Gabrielli A. P. Bom ◽  
Juliana G. D. S. Carvalho ◽  
Cristiane R. B. Parabocz ◽  
...  
2010 ◽  
Vol 25 (5) ◽  
pp. 685-705 ◽  
Author(s):  
MARÍA EMMA PARENTE ◽  
GASTÓN ARES ◽  
ANA VICTORIA MANZONI

2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Nina M. Muñoz ◽  
Crystal Dupuis ◽  
Malea Williams ◽  
Katherine Dixon ◽  
Amanda McWatters ◽  
...  

AbstractThermal ablation is a standard therapy for patients with hepatocellular carcinoma (HCC). Contemporary ablation devices are imperfect, as they lack tumor specificity. An ideal ablation modality would generate thermal energy only within tumoral tissue. Furthermore, as hyperthermia is known to influence tumor immunity, such a tumor-specific ablation modality may have the ability to favorably modulate the tumor immune landscape. Here we show a clinically relevant thermal ablation modality that generates tumor-specific hyperthermia, termed molecularly targeted photothermal ablation (MTPA), that is based upon the excellent localization of indocyanine green to HCC. In a syngeneic rat model, we demonstrate the tumor-specific hyperthermia generated by MTPA. We also show through spatial and transcriptomic profiling techniques that MTPA favorably modulates the intratumoral myeloid population towards tumor immunogenicity and diminishes the systemic release of oncogenic cytokines relative to conventional ablation modalities.


Molecules ◽  
2021 ◽  
Vol 26 (7) ◽  
pp. 2021
Author(s):  
Aneta Prokopová ◽  
Jana Pavlačková ◽  
Pavel Mokrejš ◽  
Robert Gál

Chicken stomachs can be processed into collagen hydrolysate usable in cosmetic products. The aim of the study was to verify the effects of a carbopol gel formulation enriched with 1.0% (w/w) chicken hydrolysate on the properties of the skin in the periorbital area after regular application twice a day for eight weeks in volunteers ageed 50 ± 9 years. Skin hydration, transepidermal water loss (TEWL), skin elasticity and skin relief were evaluated. Overall, skin hydration increased by 11.82% and 9.45%, TEWL decreased by 25.70% and 17.80% (always reported for the right and left area). Generally, there was an increase in skin elasticity, a decrease in skin roughness, as the resonance times decreased by 85%. The average reduction of wrinkles was 35.40% on the right and 41.20% on the left. For all results, it can be seen that the longer the cosmetic gel formulation is applied, the better the results. Due to the positive effect on the quality and functionality of the skin, it is possible to apply the cosmetic gel formulation in the periorbital area. The advantage of the product with chicken collagen hydrolysate is also the biocompatibility with the skin and the biodegradability of the formulation.


1985 ◽  
Vol 4 (3) ◽  
pp. 1-22 ◽  

Isostearyl Neopentanoate, the ester of Isostearyl Alcohol and Neopentanoic Acid, is used in cosmetic products as an emollient at concentrations up to 50 percent. The undiluted ingredient at doses up to 4 ml/kg was shown to be relatively non-toxic in short-and long-term feeding studies. Test data from animal and clinical studies indicate the undiluted ingredient is neither an irritant nor a sensitizer. A cosmetic formulation containing 16 percent Isostearyl Neopentanoate produced no phototoxicity and no photoallergenicity. Mutagenicity, carcinogenicity, and teratogenicity data were not available. Isostearyl Neopentanoate was not considered to be a significant comedogenic agent. On the basis of available data, it is concluded that this ingredient is safe as a cosmetic ingredient in its present practices of use.


2004 ◽  
Vol 28 (1) ◽  
pp. 63-76 ◽  
Author(s):  
Yi Hu ◽  
Xuan Huang ◽  
Grace Y. J. Chen ◽  
Shao Q. Yao

Author(s):  
Natã M. Barbosa ◽  
Gang Wang ◽  
Blase Ur ◽  
Yang Wang

To enable targeted ads, companies profile Internet users, automatically inferring potential interests and demographics. While current profiling centers on users' web browsing data, smartphones and other devices with rich sensing capabilities portend profiling techniques that draw on methods from ubiquitous computing. Unfortunately, even existing profiling and ad-targeting practices remain opaque to users, engendering distrust, resignation, and privacy concerns. We hypothesized that making profiling visible at the time and place it occurs might help users better understand and engage with automatically constructed profiles. To this end, we built a technology probe that surfaces the incremental construction of user profiles from both web browsing and activities in the physical world. The probe explores transparency and control of profile construction in real time. We conducted a two-week field deployment of this probe with 25 participants. We found that increasing the visibility of profiling helped participants anticipate how certain actions can trigger specific ads. Participants' desired engagement with their profile differed in part based on their overall attitudes toward ads. Furthermore, participants expected algorithms would automatically determine when an inference was inaccurate, no longer relevant, or off-limits. Current techniques typically do not do this. Overall, our findings suggest that leveraging opportunistic moments within pervasive computing to engage users with their own inferred profiles can create more trustworthy and positive experiences with targeted ads.


2010 ◽  
Vol 46 (1) ◽  
pp. 129-134 ◽  
Author(s):  
Mariana Mandelli de Almeida ◽  
Cibele Rosana Ribeiro de Castro Lima ◽  
Joyce Santos Quenca-Guillen ◽  
Elder Moscardini Filho ◽  
Lucildes Pita Mercuri ◽  
...  

In view of the increase in the number of cosmetic preparations containing antioxidant vitamins, chiefly, due to their action in preventing the process of skin aging, there is a need to develop pre-formulation studies and to validate analytical methods in order to obtain high quality products. Thus, the objective of this research was to evaluate and compare the thermal behavior of tocopheryl acetate and ascorbyl tetraisopalmitate as raw materials, and incorporated into a base cream. Thermogravimetry (TG / DTG) and differential scanning calorimetry (DSC) were used for this purpose. Both vitamins were found to be stable up to 250ºC. The base cream (placebo) and the sample (base cream containing the vitamins) presented different weight loss. Thermal analysis has shown itself to be an excellent tool for the characterization of these vitamins and can be used in routine analysis for quality control of this type of cosmetic formulation.


1989 ◽  
Vol 1 (2) ◽  
pp. 69-73 ◽  
Author(s):  
C Guy ◽  
JR Piggott ◽  
S Marie

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