Exclusive breastfeeding is associated with reduced cow's milk sensitization in early childhood

2014 ◽  
Vol 25 (5) ◽  
pp. 456-461 ◽  
Author(s):  
Sui-Ling Liao ◽  
Shen-Hao Lai ◽  
Kuo-Wei Yeh ◽  
Yu-Lin Huang ◽  
Tsung-Chieh Yao ◽  
...  
Keyword(s):  
Early Childhood ◽  
Exclusive Breastfeeding ◽  
Cow’S Milk ◽  
Cow's Milk

scholarly journals Dietary Patterns and Risk of Obesity and Early Childhood Caries in Australian Toddlers: Findings from an Australian Cohort Study

Nutrients ◽  
2019 ◽  
Vol 11 (11) ◽  
pp. 2828 ◽  
Author(s):  
Lucinda K. Bell ◽  
Celeste Schammer ◽  
Gemma Devenish ◽  
Diep Ha ◽  
Murray W. Thomson ◽  
...  
Keyword(s):  
Early Childhood ◽  
Dietary Patterns ◽  
Early Childhood Caries ◽  
Cow’S Milk ◽  
Free Sugars ◽  
Cow's Milk ◽  
Dietary Guideline ◽  
Intermediate Outcomes ◽  
Diet Pattern ◽  
Childhood Caries

We examined associations between dietary patterns at 12 months, characterised using multiple methodologies, and risk of obesity and early childhood caries (ECC) at 24–36 months. Participants were Australian toddlers (n = 1170) from the Study of Mothers’ and Infants’ Life Events affecting oral health (SMILE) birth cohort. Principal Components Analysis (PCA) and the Dietary Guideline Index for Children and Adolescents (DGI-CA) were applied to dietary intake data (1, 2 or 3-days) at 12 months, and regression analysis used to examine associations of dietary patterns with body mass index Z-score and presence of ECC at 24–36 months. Two dietary patterns were extracted using PCA: family diet and cow’s milk and discretionary combination. The mean DGI-CA score was 56 ± 13 (out of a possible 100). No statistically significant or clinically meaningful associations were found between dietary pattern or DGI-CA scores, and BMI Z-scores or ECC (n = 680). Higher cow’s milk and discretionary combination pattern scores were associated with higher energy and free sugars intakes, and higher family diet pattern scores and DGI-CA scores with lower free sugars intakes. The association between dietary patterns and intermediate outcomes of free sugars and energy intakes suggests that obesity and/or ECC may not yet have manifested, and thus longitudinal investigation beyond two years of age is warranted.

Goat’s Milk, Plant-based Milk, Cow’s Milk, and Serum 25-hydroxyvitamin D Levels in Early Childhood

Epidemiology ◽  
2016 ◽  
Vol 27 (4) ◽  
pp. e29-e31 ◽  
Author(s):  
Grace J. Lee ◽  
Catherine S. Birken ◽  
Patricia C. Parkin ◽  
Gerald Lebovic ◽  
Yang Chen ◽  
...  
Keyword(s):  
Early Childhood ◽  
Cow’S Milk ◽  
Cow's Milk ◽  
Hydroxyvitamin D ◽  
Goat’S Milk ◽  
25 Hydroxyvitamin D ◽  
Goat's Milk

scholarly journals Food-induced anaphylaxis in early childhood and factors associated with its severity

2021 ◽  
Vol 42 (5) ◽  
pp. e135-e144 ◽  
Author(s):  
Metin Aydogan ◽  
Erdem Topal ◽  
Nalan Yakıcı ◽  
Hazal Cansu Acar ◽  
Zeynep Hızlı Demirkale ◽  
...  
Keyword(s):  
Early Childhood ◽  
Cow’S Milk ◽  
Cow's Milk ◽  
Factors Associated ◽  
Pediatric Allergy ◽  
Severe Anaphylaxis ◽  
Medical Chart Review ◽  
Allergy And Immunology ◽  
Hen’S Egg ◽  
History Of

Background: Several factors that increase the risk of severe food-induced anaphylaxis have been identified. Objective: We aimed to determine the demographic, etiologic, and clinical features of food-induced anaphylaxis in early childhood and also any other factors associated with severe anaphylaxis. Methods: We carried out a medical chart review of anaphylaxis cases from 16 pediatric allergy and immunology centers in Turkey. Results: The data of 227 patients with 266 food-induced anaphylaxis episodes were included in the study. The median (interquartile range) age of the first anaphylaxis episode was 9 months (6‐18 months); 160 of these patients were boys (70.5%). The anaphylaxis episodes were mild in 75 cases (28.2%), moderate in 154 cases (57.9%), and severe in 37 cases (13.9%). The most frequent food allergens involved were cow's milk (47.4%), nuts (16.7%), and hen's egg (15.8%). Epinephrine was administered in only 98 (36.8%) of these anaphylaxis episodes. A logistic regression analysis revealed two statistically significant factors that were independently associated with severe anaphylaxis: the presence of angioedema and hoarseness during the anaphylactic episode. Urticaria was observed less frequently in patients who developed hypotension. In addition, confusion and syncope were associated with 25.9- and 44.6-fold increases, respectively, in the risk of concomitant hypotension. Conclusion: Cow's milk, nuts, and hen's egg caused the majority of mild and moderate-to-severe anaphylaxis episodes. The presence of angioedema and hoarseness in any patient who presents with a history of food-induced anaphylaxis should alert clinicians that the reaction may be severe. In addition, the presence of confusion, syncope, or stridor probably indicates concomitant hypotension.

The Relationship Between Cow's Milk and Stores of Vitamin D and Iron in Early Childhood

PEDIATRICS ◽  
2012 ◽  
Vol 131 (1) ◽  
pp. e144-e151 ◽  
Author(s):  
J. L. Maguire ◽  
G. Lebovic ◽  
S. Kandasamy ◽  
M. Khovratovich ◽  
M. Mamdani ◽  
...  
Keyword(s):  
Vitamin D ◽  
Early Childhood ◽  
Cow’S Milk ◽  
Cow's Milk ◽  
The Relationship

scholarly journals Consumption of non-cow's milk beverages and serum vitamin D levels in early childhood

2014 ◽  
Vol 186 (17) ◽  
pp. 1287-1293 ◽  
Author(s):  
G. J. Lee ◽  
C. S. Birken ◽  
P. C. Parkin ◽  
G. Lebovic ◽  
Y. Chen ◽  
...  
Keyword(s):  
Vitamin D ◽  
Early Childhood ◽  
Serum Vitamin ◽  
Cow’S Milk ◽  
Cow's Milk ◽  
Serum Vitamin D ◽  
Vitamin D Levels

scholarly journals The clinical burden of cow's milk allergy in early childhood: A retrospective cohort study

2021 ◽  
Author(s):  
Katy Sorensen ◽  
Rosan Meyer ◽  
Kate E. Grimshaw ◽  
Abbie L. Cawood ◽  
Dionisio Acosta‐Mena ◽  
...  
Keyword(s):  
Early Childhood ◽  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Cow’S Milk Allergy ◽  
Cow’S Milk ◽  
Milk Allergy ◽  
Cow's Milk ◽  
Cow's Milk Allergy ◽  
Clinical Burden

scholarly journals Consumption of Cow’s Milk in Early Childhood and Fracture Risk: A Prospective Cohort Study

2019 ◽  
Vol 189 (2) ◽  
pp. 146-155
Author(s):  
Riley M Allison ◽  
Catherine S Birken ◽  
Gerald Lebovic ◽  
Andrew W Howard ◽  
Mary R L’Abbe ◽  
...  
Keyword(s):  
Early Childhood ◽  
Cohort Study ◽  
Relative Risk ◽  
Fracture Risk ◽  
Milk Fat ◽  
Fat Content ◽  
Cow’S Milk ◽  
Adjusted Relative Risk ◽  
Cow's Milk ◽  
Milk Volume

Abstract Cow’s milk is consumed by most North American children, yet the relationships between the volume and fat content of cow’s milk consumed and childhood fracture risk are unclear. Our primary objectives in this study were to evaluate whether the volume or fat content of cow’s milk consumed at 1–3 years of age was associated with the risk of fracture between 3 and 10 years of age. This was a prospective cohort study of 2,466 children enrolled in Toronto, Ontario, Canada, between 2008 and 2016. The primary exposure was volume of cow’s milk consumed between the ages of 1 and 3 years, and the secondary exposure was average percentage of milk fat consumed by each child during the same period. The primary outcome was a parental report of child fracture at ages 3–10 years. In the primary and secondary adjusted analyses, no association between milk volume and fracture risk (adjusted relative risk = 1.04, 95% confidence interval: 0.87, 1.26) or between milk-fat content and fracture risk (adjusted relative risk = 1.05, 95% confidence interval: 0.84, 1.31) was observed. In this study, we did not identify a protective association of early childhood cow’s milk volume or fat consumption with fracture risk in later childhood. Future prospective research is needed to understand whether cow’s milk is beneficial for fracture prevention through the life course.

Enteric disease in Early Childhood Inhibits Microvillus Expression by Potential Stem Cells

1993 ◽  
Vol 84 (4) ◽  
pp. 377-379 ◽  
Author(s):  
M. Borg ◽  
A. D. Phillips ◽  
M. W. Smith ◽  
D. Brown
Keyword(s):  
Stem Cells ◽  
Early Childhood ◽  
Coeliac Disease ◽  
Milk Protein ◽  
Cow’S Milk ◽  
Healthy Children ◽  
Enteric Disease ◽  
Cow's Milk ◽  
Mature Adults ◽  
Protein Intolerance

1. Enterocyte development of microvillus structure has been measured in intestinal biopsies obtained from children suffering from coeliac disease, cow's milk protein intolerance and microvillus atrophy, and the results compared with similar measurements carried out in control children. 2. All types of enteric disease caused a significant 30% reduction in the length of microvilli present on undifferentiated basal crypt enterocytes, here referred to as potential stem cells. 3. Microvillus growth measured in control enterocytes took place mainly over the basal third of the villus. There was then little further change in structure during subsequent enterocyte migration to the villus tip. 4. Microvillus length in diseased tissue remained more or less constant during enterocyte migration to the crypt-villus junction. Microvillus length then decreased slightly during subsequent enterocyte migration over stunted villi. 5. The present results are discussed in relation to the supposed properties of potential stem cells. Comparisons are also made between profiles of microvillus development measured in healthy children and mature adults.

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