scholarly journals Rebuilding Ourselves

2013 ◽  
Vol 135 (02) ◽  
pp. 30-35
Author(s):  
Rohit Karnik ◽  
Robert S. Langer
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Infectious Diseases ◽  
Artificial Organs ◽  
Size And Shape ◽  
The Future

This study explores the application of nanotechnology in the treatment of diseases and creating artificial organs. Nanotechnology enables new types of therapies that do not use drugs. This would enable physicians to treat infections and tumors that resist medication and are difficult to remove surgically. Nanoparticles could also be used as diagnostics. Nanomaterials promise a combination of approaches that may overcome some of these limitations on drug delivery. Researchers believe that nanotechnology can also help us alter natural designs. If tissue engineering represents the promise of the future, then nanomedicine is the emerging reality of the present. Nanotherapeutics to treat pain and infectious diseases are under development as well. Nanotechnology is well suited for delivering medications. Experts have tested that rationally designed nanocarriers can take advantage of size and shape. Nanomedicine is rapidly moving into the mainstream and is poised to increasingly influence the treatment of diseases such as cancer.

scholarly journals Nanotechnology, Nanomedicine, and the Kidney

2021 ◽  
Vol 11 (16) ◽  
pp. 7187
Author(s):  
Peter V. Hauser ◽  
Hsiao-Min Chang ◽  
Norimoto Yanagawa ◽  
Morgan Hamon
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Renal Clearance ◽  
Waste Products ◽  
Fluid Homeostasis ◽  
Primary Function ◽  
Drug Removal ◽  
Main Pathway ◽  
The Future

The kidneys are vital organs performing several essential functions. Their primary function is the filtration of blood and the removal of metabolic waste products as well as fluid homeostasis. Renal filtration is the main pathway for drug removal, highlighting the importance of this organ to the growing field of nanomedicine. The kidneys (i) have a key role in the transport and clearance of nanoparticles (NPs), (ii) are exposed to potential NPs’ toxicity, and (iii) are the targets of diseases that nanomedicine can study, detect, and treat. In this review, we aim to summarize the latest research on kidney-nanoparticle interaction. We first give a brief overview of the kidney’s anatomy and renal filtration, describe how nanoparticle characteristics influence their renal clearance, and the approaches taken to image and treat the kidney, including drug delivery and tissue engineering. Finally, we discuss the future and some of the challenges faced by nanomedicine.

scholarly journals Medical applications of membranes: Drug delivery, artificial organs and tissue engineering

2008 ◽  
Vol 308 (1-2) ◽  
pp. 1-34 ◽  
Author(s):  
Dimitrios F. Stamatialis ◽  
Bernke J. Papenburg ◽  
Miriam Gironés ◽  
Saiful Saiful ◽  
Srivatsa N.M. Bettahalli ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Artificial Organs ◽  
Medical Applications

scholarly journals 4D Printing: Materials, Technologies, and Future Applications in the Biomedical Field

2020 ◽  
Vol 12 (24) ◽  
pp. 10628
Author(s):  
Ankur Bajpai ◽  
Anna Baigent ◽  
Sakshika Raghav ◽  
Conchúr Ó. Brádaigh ◽  
Vasileios Koutsos ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Smart Materials ◽  
Artificial Organs ◽  
4D Printing ◽  
Medical Treatments ◽  
Aerospace Manufacturing ◽  
Potential Applications ◽  
Biomedical Field ◽  
Research Investments

4D printing can be defined as the fabrication of structures using smart materials that allow the final object to change its shape, properties, or function in response to an external stimulus such as light, heat, or moisture. The available technologies, materials, and applications have evolved significantly since their first development in 2013, with prospective applications within the aerospace, manufacturing, and soft robotic industries. This review focuses on the printing technologies and smart materials currently available for fabricating these structures. The applications of 4D printing within biomedicine are explored with a focus on tissue engineering, drug delivery, and artificial organs. Finally, some ideas for potential uses are proposed. 4D printing is making its mark with seemingly unlimited potential applications, however, its use in mainstream medical treatments relies on further developments and extensive research investments.

The future perspectives of natural materials for pulmonary drug delivery and lung tissue engineering

2014 ◽  
Vol 12 (6) ◽  
pp. 869-887 ◽  
Author(s):  
Sally Yunsun Kim ◽  
Alice Hai May Wong ◽  
Ensanya Ali Abou Neel ◽  
Wojciech Chrzanowski ◽  
Hak-Kim Chan
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Lung Tissue ◽  
Pulmonary Drug Delivery ◽  
Future Perspectives ◽  
Natural Materials ◽  
The Future ◽  
Lung Tissue Engineering

COMBINED VACCINES – THE FUTURE OF INFECTIOUS DISEASES PREVENTION

2017 ◽  
Vol 96 (4) ◽  
pp. 135-139
Author(s):  
M. P. Kostinov ◽  
◽  
A. M. Kostinova ◽  
◽  
Keyword(s):  
Infectious Diseases ◽  
The Future

Scaffolds for Drug Delivery in Tissue Engineering

2008 ◽  
Vol 1 (2) ◽  
pp. 113-123 ◽  
Author(s):  
Vikas V. Gaikwad ◽  
Abasaheb B. Patil ◽  
Madhuri V. Gaikwad
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Heart Diseases ◽  
Cartilage Regeneration ◽  
Tissue Growth ◽  
The Body ◽  
Patient Specific ◽  
In Situ Gel ◽  
Heart Muscle Cells

Scaffolds are used for drug delivery in tissue engineering as this system is a highly porous structure to allow tissue growth.  Although several tissues in the body can regenerate, other tissue such as heart muscles and nerves lack regeneration in adults. However, these can be regenerated by supplying the cells generated using tissue engineering from outside. For instance, in many heart diseases, there is need for heart valve transplantation and unfortunately, within 10 years of initial valve replacement, 50–60% of patients will experience prosthesis associated problems requiring reoperation. This could be avoided by transplantation of heart muscle cells that can regenerate. Delivery of these cells to the respective tissues is not an easy task and this could be done with the help of scaffolds. In situ gel forming scaffolds can also be used for the bone and cartilage regeneration. They can be injected anywhere and can take the shape of a tissue defect, avoiding the need for patient specific scaffold prefabrication and they also have other advantages. Scaffolds are prepared by biodegradable material that result in minimal immune and inflammatory response. Some of the very important issues regarding scaffolds as drug delivery systems is reviewed in this article.

Hydrogels as Antibacterial Biomaterials

2018 ◽  
Vol 24 (8) ◽  
pp. 843-854 ◽  
Author(s):  
Weiguo Xu ◽  
Shujun Dong ◽  
Yuping Han ◽  
Shuqiang Li ◽  
Yang Liu
Keyword(s):  
Mechanical Properties ◽  
Drug Delivery ◽  
Tissue Engineering ◽  
Water Content ◽  
Oxygen Permeability ◽  
Structural Diversity ◽  
High Water ◽  
Clinical Applications ◽  
High Water Content ◽  
Biomedical Field

Hydrogels, as a class of materials for tissue engineering and drug delivery, have high water content and solid-like mechanical properties. Currently, hydrogels with an antibacterial function are a research hotspot in biomedical field. Many advanced antibacterial hydrogels have been developed, each possessing unique qualities, namely high water swellability, high oxygen permeability, improved biocompatibility, ease of loading and releasing drugs and structural diversity. In this article, an overview is provided on the preparation and applications of various antibacterial hydrogels. Furthermore, the prospects in biomedical researches and clinical applications are predicted.

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