scholarly journals Damping Pressure Pulsations in a Wave-Powered Desalination System

2014 ◽  
Vol 136 (2) ◽  
Author(s):  
Brandon J. Hopkins ◽  
Nikhil Padhye ◽  
Alison Greenlee ◽  
James Torres ◽  
Levon Thomas ◽  
...  
Keyword(s):  
Constant Pressure ◽  
Low Cost ◽  
Pressure Fluctuations ◽  
Cost Effective ◽  
Coastal Communities ◽  
Pressure Pulsations ◽  
Pressure Flow ◽  
Reliable Source ◽  
Effective Option ◽  
Elastic Pipes

Wave-driven reverse osmosis desalination systems can be a cost-effective option for providing a safe and reliable source of drinking water for large coastal communities. Such systems usually require the stabilization of pulsating pressures for desalination purposes. The key challenge is to convert a fluctuating pressure flow into a constant pressure flow. To address this task, stub-filters, accumulators, and radially elastic-pipes are considered for smoothing the pressure fluctuations in the flow. An analytical model for fluidic capacitance of accumulators and elastic pipes are derived and verified. Commercially available accumulators in combination with essentially rigid (and low cost) piping are found to be a cost-effective solution for this application, and a model for selecting accumulators with the required fluidic-capacitance for the intended system is thus presented.

scholarly journals Sugarcane Bagasse as an Efficient Biosorbent for Methylene Blue Removal: Kinetics, Isotherms and Thermodynamics

2020 ◽  
Vol 17 (2) ◽  
pp. 526 ◽  
Author(s):  
Thaisa Caroline Andrade Siqueira ◽  
Isabella Zanette da Silva ◽  
Andressa Jenifer Rubio ◽  
Rosângela Bergamasco ◽  
Francielli Gasparotto ◽  
...  
Keyword(s):  
Methylene Blue ◽  
Sugarcane Bagasse ◽  
Adsorption Isotherms ◽  
Low Cost ◽  
Cost Effective ◽  
Blue Dye ◽  
Maximum Adsorption Capacity ◽  
Effective Option ◽  
Pseudo Second Order ◽  
Isotherms And Thermodynamics

Adsorption in biomass has proven to be a cost-effective option for treatment of wastewater containing dyes and other pollutants, as it is a simple and low cost technique and does not require high initial investments. The present work aimed to study the adsorption of methylene blue dye (MB) using sugarcane bagasse (SCB). The biomass was characterized by scanning electron microscopy (SEM). Adsorption studies were conducted batchwise. Kinetics, adsorption isotherms, and thermodynamics were studied. The results showed that SCB presented a maximum adsorption capacity of 9.41 mg g−1 at 45 °C after 24 h of contact time. Adsorption kinetics data better fitted the pseudo-second order model, indicating a chemical process was involved. The Sips’s three-parameter isotherm model was better for adjusting the data obtained for the adsorption isotherms, indicating a heterogeneous adsorption process. The process showed to be endothermic, spontaneous, and feasible. Therefore, it was concluded that SCB presented as a potential biosorbent material for the treatment of MB-contaminated waters.

scholarly journals Response Surface Optimization of Fixed Bed Adsorption of Cr+6 Onto Low-cost Adsorbent

2020 ◽  
Vol 15 (3) ◽  
pp. 632-639
Author(s):  
Padmaja Megham ◽  
R Bhavani
Keyword(s):  
Response Surface ◽  
Low Cost ◽  
Fixed Bed ◽  
Cost Effective ◽  
P Value ◽  
Response Surface Optimization ◽  
Shrimp Shell ◽  
Fixed Bed Adsorption ◽  
Effective Option ◽  
Shrimp Shell Waste

The paper emphasizes the removal ofChromium from tanning industryeffluent using adsorption as a cost effective option. The essential source of contamination identified from variable amounts of liquid discharges was Chromium (Cr+6). A column study was carried out using Shrimp shell waste (SSW) as an adsorbent in the removal of Cr+6 ion from synthetic solutions. Operational factors such as the size of adsorbent, bed depthand compared their adsorption capacities thereof. For a given size, the adsorption capacity increased by a reduction in the amount of Chromium. TheCr+6removal based on adsorbent size was in the order: 150 microns> 300 microns> 600 microns.The experimental data was optimized and modelled using Response Surface method, and a 23 factorial Central composite design (CCD) was applied, and the data was analyzed for ANOVA. A P-Value<0.005 indicated that the probability of the experimental results was significant.

scholarly journals Inhalable Nanobody (PiN-21) prevents and treats SARS-CoV-2 infections in Syrian hamsters at ultra-low doses

2021 ◽  
Author(s):  
Sham Nambulli ◽  
Yufei Xiang ◽  
Natasha L. Tilston-Lunel ◽  
Linda J. Rennick ◽  
Zhe Sang ◽  
...  
Keyword(s):  
Weight Loss ◽  
Low Cost ◽  
Cost Effective ◽  
Therapeutic Interventions ◽  
Lung Pathology ◽  
Aerosol Delivery ◽  
Upper Airways ◽  
Novel Therapy ◽  
Syrian Hamsters ◽  
Effective Option

AbstractGlobally there is an urgency to develop effective, low-cost therapeutic interventions for coronavirus disease 2019 (COVID-19). We previously generated the stable and ultrapotent homotrimeric Pittsburgh inhalable Nanobody 21 (PiN-21). Using Syrian hamsters that model moderate to severe COVID-19 disease, we demonstrate the high efficacy of PiN-21 to prevent and treat SARS-CoV-2 infection. Intranasal delivery of PiN-21 at 0.6 mg/kg protects infected animals from weight loss and substantially reduces viral burdens in both lower and upper airways compared to control. Aerosol delivery of PiN-21 facilitates deposition throughout the respiratory tract and dose minimization to 0.2 mg/kg. Inhalation treatment quickly reverses animals’ weight loss post-infection and decreases lung viral titers by 6 logs leading to drastically mitigated lung pathology and prevents viral pneumonia. Combined with the marked stability and low production cost, this novel therapy may provide a convenient and cost-effective option to mitigate the ongoing pandemic.

scholarly journals Assessment of Electricity-Free Hydroponics in India: A Proof of Concept Field Study

2017 ◽  
Vol 10 (1) ◽  
pp. 45
Author(s):  
Indira Roy ◽  
Yelena Naumova ◽  
A. J. Both
Keyword(s):  
Smallholder Farmers ◽  
Low Cost ◽  
Cost Effective ◽  
Dry Mass ◽  
Chili Pepper ◽  
Production Costs ◽  
Effective Option ◽  
Deccan Plateau ◽  
Set Up ◽  
The Cost

Subsistence and smallholder farmers in the Deccan plateau region of India struggle with a predominantly hot and dry climate and often accumulated debt due to the cost of fertilizer that they need to increase yields for profitability. While a low-cost deep-flow technique hydroponic growing system (DFT) as a supplement to soil-based agriculture could help reduce debt, the cost of electricity needed to operate the DFT makes it inaccessible to these farmers. The objective of this project was to test the viability of electricity-free DFT which would substantially reduce production costs. Two DFT systems were set up in a shade net house and prepared with identical nutrients to grow chili pepper seedlings. Each DFT system was oxygenated for 30 minutes per day, one system using an electrical air pump, and the other system was oxygenated manually. After four weeks of growth, the dry mass of the shoots of the chili pepper seedlings in each system was measured. While the pump-oxygenated DFT system produced more dry matter, the manually-oxygenated system produced a larger number of visually healthier plants. Therefore, we conclude that electricity-free DFT hydroponics may be a viable alternative to pump-oxygenated DFT hydroponics, making hydroponic farming a cost-effective option for poor farmers.

scholarly journals Inhalable Nanobody (PiN-21) prevents and treats SARS-CoV-2 infections in Syrian hamsters at ultra-low doses

2021 ◽  
Vol 7 (22) ◽  
pp. eabh0319
Author(s):  
Sham Nambulli ◽  
Yufei Xiang ◽  
Natasha L. Tilston-Lunel ◽  
Linda J. Rennick ◽  
Zhe Sang ◽  
...  
Keyword(s):  
Weight Loss ◽  
Low Cost ◽  
Cost Effective ◽  
Therapeutic Interventions ◽  
Lung Pathology ◽  
Aerosol Delivery ◽  
Upper Airways ◽  
Syrian Hamsters ◽  
Innovative Therapy ◽  
Effective Option

Globally, there is an urgency to develop effective, low-cost therapeutic interventions for coronavirus disease 2019 (COVID-19). We previously generated the stable and ultrapotent homotrimeric Pittsburgh inhalable Nanobody 21 (PiN-21). Using Syrian hamsters that model moderate to severe COVID-19 disease, we demonstrate the high efficacy of PiN-21 to prevent and treat SARS-CoV-2 infection. Intranasal delivery of PiN-21 at 0.6 mg/kg protects infected animals from weight loss and substantially reduces viral burdens in both lower and upper airways compared to control. Aerosol delivery of PiN-21 facilitates deposition throughout the respiratory tract and dose minimization to 0.2 mg/kg. Inhalation treatment quickly reverses animals’ weight loss after infection, decreases lung viral titers by 6 logs leading to drastically mitigated lung pathology, and prevents viral pneumonia. Combined with the marked stability and low production cost, this innovative therapy may provide a convenient and cost-effective option to mitigate the ongoing pandemic.

scholarly journals Microfluidics made easy: A robust low-cost constant pressure flow controller for engineers and cell biologists

2016 ◽  
Vol 10 (3) ◽  
pp. 034107 ◽  
Author(s):  
Nicholas Mavrogiannis ◽  
Markela Ibo ◽  
Xiaotong Fu ◽  
Francesca Crivellari ◽  
Zachary Gagnon
Keyword(s):  
Constant Pressure ◽  
Low Cost ◽  
Pressure Flow ◽  
Flow Controller

scholarly journals Role of seton versus conventional techniques in the management of anorectal fistulas

2020 ◽  
Vol 7 (7) ◽  
pp. 2235
Author(s):  
Mohammad Sadik Akhtar ◽  
Sheikh Saif Alim ◽  
Mohammad Habib Raza ◽  
Wasif Mohammad Ali
Keyword(s):  
Low Cost ◽  
Randomized Study ◽  
Cost Effective ◽  
Pregnant Females ◽  
Recurrent Fistula ◽  
Effective Option ◽  
Complex Fistula ◽  
Males And Females ◽  
Cutting Seton

Background: This study was conducted to compare the use of different setons with conventional management like fistulotomy and fistulectomy in terms of healing (after 1 and 3 months), recurrence and incontinence.Methods: This was a retrospective non-randomized study conducted at JNMCH, Aligarh from January 2018 to June 2019. Patients included- patients (males and females) of age group 18-70 years, patients giving consent. Patients excluded- fistula secondary to- Crohn’s disease, tuberculosis, malignancy, recurrent fistula, pregnant females, immuno-suppressed patients.Results: After 1 month, 17 out of 24 patients (70.8%) of fistulotomy, 48 out of 68 patients (70.6%) of seton group and 21 out of 32 patients (65.6%) of fistulectomy group had their wounds healed (p=0.8693). After 3 months, 19 out of 24 (79.2%) patients of fistulotomy, 61 out of 68 (89.7%) of seton, and 24 out of 32 patients (75%) with fistulectomy had their wound healed (p=0.1374). Recurrence was observed in 5 out of 24 patients of fistulotomy, 10 out of 68 patients of seton use and 5 out of 32 patients with fistulectomy (p=0.7788). 6 out of 24 patients (25%) had incontinence after fistulotomy, 7 out of 68 (10.3%) of seton group and 8 out of 24 (25%) after fistulectomy (p=0.0944). Healing was higher in patients of non-cutting setons as compared to cutting seton (p=0.0252). After 3 months, no difference was observed (p=0.1245). Recurrence higher in cutting setons as compared to non-cutting setons (p=0.0187).Conclusions: Setons are safe, low-cost, less invasive, precise, and cost-effective option for treating simple and complex fistula-in-ano. 

ASSESSMENT OF THE PLATELET COUNT IN THE PREGNANT WOMEN IN IGIMS, PATNA, BIHAR

2020 ◽  
Vol 4 (2) ◽  
Author(s):  
Tanwi Singh ◽  
Anshuman Sinha
Keyword(s):  
Platelet Count ◽  
Pregnant Women ◽  
Screening Test ◽  
Low Cost ◽  
Medical Science ◽  
Cost Effective ◽  
Platelet Indices ◽  
Increased Risk ◽  
Low Platelet Count ◽  
Severity Of The Disease

The major risk associated with low platelet count in pregnancy is the increased risk of bleeding during the childbirth or post that. There is an increased blood supply to the uterus during pregnancy and the surgical procedure requires cutting of major blood vessels. Women with thrombocytopenia are at increased risk of losing excessive blood. The risk is more in case of caesarean delivery as compared to vaginal delivery. Hence based on above findings the present study was planned for Assessment of the Platelet Count in the Pregnant Women in IGIMS, Patna, Bihar. The present study was planned in Department of Pathology, Indira Gandhi Institute of Medical Science, Patna, Bihar, India. The present study was planned from duration of January 2019 to June 2019. In the present study 200 pregnant females samples received for the platelet estimation were enrolled in the present study. Clinically platelet indices can be a useful screening test for early identification of preeclampsia and eclampsia. Also platelet indices can assess the prognosis of this disease in pregnant women and can be used as an effective prognostic marker because it correlates with severity of the disease. Platelet count is a simple, low cost, and rapid routine screening test. Hence the data generated from the present study concludes that platelet count can be used as a simple and cost effective tool to monitor the progression of preeclampsia, thereby preventing complications to develop during the gestational period. Keywords: Platelet Count, Pregnant Women, IGIMS, Patna, Bihar, etc.

Janus – A New Approach to Air Combat Pilot Training

2019 ◽  
Vol 2019 (4) ◽  
pp. 7-22
Author(s):  
Georges Bridel ◽  
Zdobyslaw Goraj ◽  
Lukasz Kiszkowiak ◽  
Jean-Georges Brévot ◽  
Jean-Pierre Devaux ◽  
...  
Keyword(s):  
Low Cost ◽  
Cost Effective ◽  
High Energy ◽  
Training System ◽  
Embedded Sensors ◽  
Pilot Training ◽  
New Approach ◽  
Combat Aircraft ◽  
Air Combat ◽  
The Cost

Abstract Advanced jet training still relies on old concepts and solutions that are no longer efficient when considering the current and forthcoming changes in air combat. The cost of those old solutions to develop and maintain combat pilot skills are important, adding even more constraints to the training limitations. The requirement of having a trainer aircraft able to perform also light combat aircraft operational mission is adding unnecessary complexity and cost without any real operational advantages to air combat mission training. Thanks to emerging technologies, the JANUS project will study the feasibility of a brand-new concept of agile manoeuvrable training aircraft and an integrated training system, able to provide a live, virtual and constructive environment. The JANUS concept is based on a lightweight, low-cost, high energy aircraft associated to a ground based Integrated Training System providing simulated and emulated signals, simulated and real opponents, combined with real-time feedback on pilot’s physiological characteristics: traditionally embedded sensors are replaced with emulated signals, simulated opponents are proposed to the pilot, enabling out of sight engagement. JANUS is also providing new cost effective and more realistic solutions for “Red air aircraft” missions, organised in so-called “Aggressor Squadrons”.

Motivating Compliance: Firm Response to Mandatory Disclosure Policies

2018 ◽  
Vol 32 (2) ◽  
pp. 103-119
Author(s):  
Colleen M. Boland ◽  
Chris E. Hogan ◽  
Marilyn F. Johnson
Keyword(s):  
Conflict Of Interest ◽  
Low Cost ◽  
Cost Effective ◽  
Data Availability ◽  
Policy Adoption ◽  
Future Research ◽  
Regulated Firms ◽  
Firm Response ◽  
Disclosure Rules ◽  
The Impact

SYNOPSIS Mandatory existence disclosure rules require an organization to disclose a policy's existence, but not its content. We examine policy adoption frequencies in the year immediately after the IRS required mandatory existence disclosure by nonprofits of various governance policies. We also examine adoption frequencies in the year of the subsequent change from mandatory existence disclosure to a disclose-and-explain regime that required supplemental disclosures about the content and implementation of conflict of interest policies. Our results suggest that in areas where there is unclear regulatory authority, mandatory existence disclosure is an effective and low cost regulatory device for encouraging the adoption of policies desired by regulators, provided those policies are cost-effective for regulated firms to implement. In addition, we find that disclose-and-explain regulatory regimes provide stronger incentives for policy adoption than do mandatory existence disclosure regimes and also discourage “check the box” behavior. Future research should examine the impact of mandatory existence disclosure rules in the year that the regulation is implemented. Data Availability: Data are available from sources cited in the text.

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