Human Thoracolumbar Spine Tolerance to Injury and Mechanisms From Caudo-Cephalad Impacts

2020 ◽  
Author(s):  
Narayan Yoganandan ◽  
Prashant Khandelwal ◽  
Vaibhav Porwal ◽  
John Humm
Keyword(s):  
Load Transfer ◽  
Thoracolumbar Spine ◽  
Spinal Column ◽  
The Body ◽  
Von Mises Stress ◽  
Whole Body ◽  
Stress And Strain ◽  
Male And Female ◽  
Vertical Loading ◽  
Flexion Extension

Abstract The human thoracolumbar spinal column sustains axial loading under physiological and traumatic loading situations. Clinical studies have focused on the former scenario, and the investigation of low back pain issues and spinal stabilization using artificial devices such as arthroplasty are examples. Investigative studies have largely used quasi-static and vibration loading on the spine segment(s) and spinal columns. The traumatic loading scenario is relatively less researched, and it is a dynamic event. Injuries under this scenario occur in sports, automotive, and combat environments. Impact vectors include flexion-extension modes in automotive crash events. Vertical or caudal to cephalad oriented impacts have been identified in both automotive and military scenarios. Frontal impacts to restrained occupants in the automotive and underbody blast impacts from improvised explosive device in combat situations are examples of the vertical loading vector. Although some studies have been conducted using whole body human cadavers and isolated spinal columns, determinations have not been made of the injury risks and stress and strain responses for a variety of accelerative pulses. The aims of the present investigation were to delineate the internal biomechanics of the spinal column under this impact vector and assess the probability of injury. Male and female whole-body human finite element models were used in the study. The occupants were restrained and positioned on the seat, and caudo-cephalad impacts were applied to the base. Different acceleration-time profiles (pulse durations ranging from 50 to 200 ms and peak accelerations varying from 11 g to 46 g) were used as inputs in both male and female models. The resulting stress-strain profiles in the cortical and cancellous bones were evaluated at different vertebral levels. Using the peak transmitted forces at the thoracolumbar disc level as the response variable, the probability of injury for the male spine was obtained from experimental risk curves for the various accelerative pulses. Results showed that the shorter pulse durations and rise times impart greater loading on the thoracolumbar spine. The analysis of von Mises stress and strain distributions showed that the compression-related fractures of vertebrae are multifaceted with contributions from both the cortical and cancellous bony components of the body. Profiles are provided in the body of the paper for different spinal levels. The intervertebral disc may be involved in the fracture mechanism, because it acts as a medium of load transfer between adjacent vertebrae. Injury risks for the shortest pulse was sixty-three percent, and for the widest pulse it was close to zero, and injury probabilities for other pulses are given. The present computational modeling study provides insights into the mechanisms of the internal load transfer and describe the injury risk levels from caudal to cephalad impacts.

scholarly journals Human Thoracolumbar Spine Tolerance to Injury and Mechanisms From Caudo-Cephalad Loading: A Parametric Modeling Study

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Narayan Yoganandan ◽  
Prashant Khandelwal ◽  
Vaibhav Porwal ◽  
John Humm ◽  
Anjishnu Banerjee
Keyword(s):  
Injury Risk ◽  
Load Transfer ◽  
Thoracolumbar Spine ◽  
Parametric Modeling ◽  
The Body ◽  
Von Mises Stress ◽  
Whole Body ◽  
Risk Levels ◽  
Von Mises ◽  
Modeling Study

Abstract The aims of this investigation were to delineate the internal biomechanics of the spine under vertical impact vector and assess the probability of injury. Male and female whole-body human finite element models were used. The restrained occupants were positioned on the seat, and caudo-cephalad impacts were applied to the base. Different acceleration-time profiles (50–200 ms pulse durations, 11–46 g peak accelerations) were used as inputs in both models. The resulting stress–strain profiles in the cortical and cancellous bones were evaluated at different vertebral levels. Using the peak transmitted forces at the thoracolumbar disc level as the response variable, the probability of injury for the male spine was obtained from experimental risk curves for the various pulses. Results showed that the shorter pulse durations and rise times impart greater loading on the thoracolumbar spine. The analysis of von Mises stress and strain distributions showed that the compression-related fractures are multifaceted with contributions from both the cortical and cancellous bony components of the body. Profiles are provided in the paper. The intervertebral disc may be involved in the fracture mechanism, because it acts as a medium of load transfer between adjacent vertebrae. Injury risks for the shortest pulse was 63%, and for the widest pulse it was close to zero, and injury probabilities for other pulses are given. The present modeling study provides insights into the mechanisms of internal load transfer and describes injury risk levels from caudal to cephalad impacts.

scholarly journals A Study of Family Stress among Non-Working Married Male and Female: A Special Reference with Rural Area of Patna

2017 ◽  
Vol 4 (2) ◽  
Author(s):  
Dr. Binay Kumar Bimal
Keyword(s):  
Family Stress ◽  
The Body ◽  
Stress And Strain ◽  
Specific Response ◽  
Male And Female ◽  
Joint Influence ◽  
Significant Difference ◽  
Strain Stress ◽  
Stress Inventory ◽  
Married Male

The present age has been called the age of stress and strain. Stress is defined as “the non-specific response of the body to any demand placed upon it”. The study seeks to assess the stress level among Non-Working married Male and female. Today every individual is stress prone. It was assumed that there will be no significant difference between married male and female when family stress is taken as a dependent variable and no significant difference in family stress between non-working married male and female separately. 200 married, 100 male and 100 female were the samples for the investigation. Family stress inventory, by Dr. Abha Rani Bisht (Hindi) was used. It was found that there was no difference in family stress between in married male and female. Further concluded that there was no difference in family stress of married non- working male and female when studied separately under joint influence of sex and age.

Changthangi Goats: A rich source of pashmina production in Ladakh

2004 ◽  
Vol 35 ◽  
pp. 75-85 ◽  
Author(s):  
T.K. Bhattacharya ◽  
S.S. Misra ◽  
F.D. Sheikh ◽  
P. Kumar ◽  
A. Sharma
Keyword(s):  
Growth Hormone ◽  
Large Scale ◽  
Fibre Diameter ◽  
The Body ◽  
Whole Body ◽  
Growth Hormone Gene ◽  
Body Colour ◽  
Male And Female ◽  
Pcr Rflp ◽  
Preliminary Study

SummaryPashmina, internationally known as “cashmere”, a fine luxury fibre, is being produced from Changthangi goats bred in the Ladakh region of India. The Leh district of Greater Ladakh produces around 30 000 kg of pashmina fibre which is harvested from about 0.15 million Changthangi goats reared by the Changpa nomads in Changthang region of Greater Ladakh. Changthangi goats are sometimes also called Changra goats. Pashmina producing goats are of great importance for revitalising the economy of the poverty stricken region of Changthang and the Leh district of Ladakh. The information on Changthangi goats was collected from both small and large-scale farmers in Ladakh, and 337 animals were included in the study.The body colour of Changthangi goats varies from white to light brown and nearly whole body is covered with pashmina and long hairs. The average birth weights of male and female kids were estimated as 2.11 ± 0.3 and 2.06 ± 0.2 kg, respectively while weight at 300 days was found to be 20.0 ± 2.1 and 18.7 ± 1.9 kg in male and females respectively.The pashmina yields of bucks, does, male hoggets and female hoggets were estimated as 402 ± 19 g, 248 ± 14 g, 255 ± 12 and 280 ± 16 g, respectively. The length of pashmina fibre was found to be 4.25 ± 1.2 cm in males and 4.02 ± 1.5 cm in females while fibre diameter in male and female goats was estimated as 12.9 ± 2.6 μ and 13.0 ± 3.0 μ, respectively.The twining rate was found to be very low, nearly 0.3%. A preliminary study at DNA level with PCR-RFLP indicated monomorphism at the growth hormone gene. The occurrence of disease was quite low although some genetic deformities in this breed were not uncommon.

scholarly journals Keragaan Fenotipe Ikan Tambakan (Helostoma temminkii. Cuvier 1829) Hasil Domestikasi (Takhasi)

2017 ◽  
Vol 12 (1) ◽  
pp. 1
Author(s):  
Otong Zenal Arifin ◽  
Wahyulia Cahyanti ◽  
Jojo Subagja ◽  
Anang Hari Kristanto
Keyword(s):  
Standard Length ◽  
Body Shape ◽  
The Body ◽  
Whole Body ◽  
Female Fish ◽  
Male Fish ◽  
Yellow Colour ◽  
Male And Female ◽  
Green Colour ◽  
Freshwater Aquaculture

Ikan tambakan berpotensi dibudidayakan karena memiliki keunggulan seperti kemampuan beradaptasi terhadap perairan dengan kadar oksigen terlarut rendah dan tergolong ikan dengan nilai fekunditas yang tinggi. Penelitian untuk mengetahui keragaan fenotipe ikan tambakan hasil domestikasi telah dilakukan di Balai Riset Perikanan Budidaya Air Tawar dan Penyuluhan Perikanan, Bogor. Tujuan dari penelitian ini adalah untuk mengkarakterisasi bentuk morfologi berdasarkan morfometrik, meristik, dan warna yang berguna dalam pengelolaan pembenihan dan budidaya ikan tambakan. Pengambilan data dilakukan melalui pengamatan bentuk tubuh dan genitalia ikan jantan dan betina, pengukuran bagian tubuh, penghitungan jumlah dan jenis jari sirip, linea lateralis, warna ikan dan morfometrik. Hasil yang diperoleh menunjukkan bentuk tubuh ikan jantan lebih ramping dibanding ikan betina, ikan betina mempunyai rasio panjang standar terhadap tinggi badan sebesar 2,08±0,117; ikan jantan sebesar 2,26±0,095. Rasio panjang standar terhadap lebar badan pada ikan jantan adalah 0,95±0,018 dan ikan betina 1,01±0,025. Nilai koefisien variasi (CV) rerata seluruh karakter tubuh tergolong rendah, dengan nilai 12,2±10,73. Karakter C4 (awal sirip dorsal-akhir sirip anal) merupakan karakter nilai CV paling rendah yaitu 3,2% dan karakter D1 (akhir sirip anal-awal sirip ekor bawah) mempunyai nilai CV tertinggi yaitu 43,8%. Berdasarkan karakter meristik dan warna, tidak terdapat perbedaan antara jantan dan betina. Warna ikan tambakan terdiri atas warna punggung hijau keabuan (TC 613), warna operculum hijau keperakan (TC 613), warna perut perak sampai keabuan (TC 521) dan warna gonad kuning oranye (TC 023).Kissing gouramy has potentially to be cultivated due to the ability to adapt on swampy waters and has high eggs fecundity. Research on phenotype performance of domesticated kissing gouramy was done at the Institute for Freshwater Aquaculture Research and Development, Bogor. The purpose of this study was to characterize morphological forms based on the morphometrics, meristics, and color of domesticated fish that will be useful in the aquaculture management. The data were collected through observation of body shape and genitalia of male and female fish, measurement of body parts, counting the number and the type of fin, linea lateralis, fish color and the morphometric measurement. The obtained results showed that the body shape of the male fish was slender than that of the female fish, the female fish had a ratio of standard length to the height of 2.08 ± 0.117, male fish of 2.26 ± 0.095. The standard length ratio to body width in male fish was 0.95 ± 0.018 and female fish was 1.01 ± 0.025. The mean value of coefficient variation (CV) of the whole body character was low, with value 12,2 ± 10,73. C4 character (beginning of dorsal fin-end of anal fin) was the lowest character of CV value of 3.2% and D1 character (final anal fin-bottom caudal fin) had the highest CV value of 43.8%. Based on the meristic and color character there was no difference between male and female. The dorsal, overculum, ventral part and matured gonad of domesticated kissing gouramy fish had gray-green colour (TC 613), silver-green colour (TC 613), silver-gray to silver colour (TC 521) and orange yellow colour (TC 023) respectively.

Appendix to a former paper on human osteology

1837 ◽  
Vol 3 ◽  
pp. 294-294
Keyword(s):  
Human Body ◽  
The Body ◽  
The Other ◽  
Whole Body ◽  
Male And Female ◽  
Human Osteology ◽  
Linear Representations ◽  
Human Bones

This appendix contains linear representations of various dimen­sions of the bones of the human body, both male and female, with a view to facilitate the comparison of the human frame with that of other animals, and reduce it to definite laws. The author states that many of the rectilinear dimensions of human bones appear to be mul­tiples of one unit, namely, the breadth of the cranium directly over the external passage of the ear; a dimension which he has found to be the most invariable in the body. No division of that dimension was found by him to measure the other dimensions so accurately as that by seven, or its multiples. Of such seventh parts there appear to be twelve in the longitudinal extent of the back, and ninety-six in the height of the whole body.

scholarly journals Neck Vertebral Level-specific Forces and Moments Under G-x Accelerative Loading

2021 ◽  
Vol 186 (Supplement_1) ◽  
pp. 625-631
Author(s):  
Yuvaraj Purushothaman ◽  
John Humm ◽  
Davidson Jebaseelan ◽  
Narayan Yoganandan
Keyword(s):  
Three Dimensional ◽  
Spinal Column ◽  
Bending Moment ◽  
Element Model ◽  
Whole Body ◽  
Shear Forces ◽  
Male And Female ◽  
Axial Forces ◽  
Impact Acceleration ◽  
Three Dimensional Finite Element

ABSTRACT Introduction It is important to determine the local forces and moments across the entire cervical spine as dysfunctions such as spondylosis and acceleration-induced injuries are focused on specific levels/segments. The aims of the study were to determine the axial and shear forces and moments at each level under G-x accelerative loading for female and male spines. Methods A three-dimensional finite element model of the male head-cervical spinal column was developed. G-x impact acceleration was applied using experimental data from whole body human cadaver tests. It was validated with experimental head kinematics. The model was converted to a female model, and the same input was applied. Segmental axial and shear forces and moments were obtained at all levels from C2 to T1 in male and female spines. Results The time of occurrence of peak axial forces in male and female spines ranged from 37 to 41 ms and 31 to 35 ms. The peak times for the shear forces in male and female spines ranged from 65 to 86 ms and 58 to 78 ms. The peak times for the bending moment ranged from 79 to 91 ms for male and 75 to 83 ms for female spines. Other data are given. Conclusions All metrics reached their peaks earlier in female than male spines, representing a quicker loading in the female spine. Peak magnitudes were also lower in the female spines. Moments and axial forces varied differently compared to the shear forces in the female spine, suggesting that intersegmental loads vary nonuniformly. Effects of head inertia contributed to the greatest increase in axial force under this impact acceleration vector. Because female spines have a lower biomechanical tolerance to injury, female spines may be more vulnerable to injury under this load vector.

A Simple and Inexpensive Clinical Whole Body Counter

1976 ◽  
Vol 15 (05) ◽  
pp. 248-253
Author(s):  
A. K. Basu ◽  
S. K. Guha ◽  
B. N. Tandon ◽  
M. M. Gupta ◽  
M. ML. Rehani
Keyword(s):  
The Body ◽  
Whole Body ◽  
Vitro Assay ◽  
Body Counter ◽  
Optimum Parameters ◽  
Whole Body Counter ◽  
Single Detector ◽  
Background Index ◽  
Iodide Crystal

SummaryThe conventional radioisotope scanner has been used as a whole body counter. The background index of the system is 10.9 counts per minute per ml of sodium iodide crystal. The sensitivity and derived sensitivity parameters have been evaluated and found to be suitable for clinical studies. The optimum parameters for a single detector at two positions above the lying subject have been obtained. It has been found that for the case of 131I measurement it is possible to assay a source located at any point in the body with coefficient of variation less than 5%. To add to the versatility, a fixed geometry for in-vitro counting of large samples has been obtained. The retention values obtained by the whole body counter have been found to correlate with those obtained by in-vitro assay of urine and stool after intravenous administration of 51Cr-albumin.

Visualization of Invasion into the Body and Internal Diffusion of Nanoparticles

2008 ◽  
Vol 396-398 ◽  
pp. 569-572
Author(s):  
Fumio Watari ◽  
Shigeaki Abe ◽  
I.D. Rosca ◽  
Atsuro Yokoyama ◽  
Motohiro Uo ◽  
...  
Keyword(s):  
Biomedical Applications ◽  
Fluorescent Microscopy ◽  
The Body ◽  
Internal Diffusion ◽  
Whole Body ◽  
X Ray ◽  
Body Level ◽  
Organ Level ◽  
Level 2 ◽  
Internal Body

Nanoparticles may invade directly into the internal body through the respiratory or digestive system and diffuse inside body. The behavior of nanoparticles in the internal body is also essential to comprehend for the realization of DDS. Thus it is necessary to reveal the internal dynamics for the proper treatments and biomedical applications of nanoparticles. In the present study the plural methods with different principles such as X-ray scanning analytical microscope (XSAM), MRI and Fluorescent microscopy were applied to enable the observation of the internal diffusion of micro/nanoparticles in the (1) whole body level, (2) inner organ level and (3) tissue and intracellular level. Chemical analysis was also done by ICP-AES for organs and compared with the results of XSAM mapping.

scholarly journals Making the choice between bioelectrical impedance measures for body hydration status assessment

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Dmitry M. Davydov ◽  
Andrey Boev ◽  
Stas Gorbunov
Keyword(s):  
Body Schema ◽  
Bioelectrical Impedance ◽  
Information Criterion ◽  
The Body ◽  
Whole Body ◽  
Hydration Status ◽  
Status Assessment ◽  
Best Fitting ◽  
Body Compartments ◽  
Fitting In

AbstractSituational or persistent body fluid deficit (i.e., de- or hypo-hydration) is considered a significant health risk factor. Bioimpedance analysis (BIA) has been suggested as an alternative to less reliable subjective and biochemical indicators of hydration status. The present study aimed to compare various BIA models in the prediction of direct measures of body compartments associated with hydration/osmolality. Fish (n = 20) was selected as a biological model for physicochemically measuring proximate body compartments associated with hydration such as water, dissolved proteins, and non-osseous minerals as the references or criterion points. Whole-body and segmental/local impedance measures were used to investigate a pool of BIA models, which were compared by Akaike Information Criterion in their ability to accurately predict the body components. Statistical models showed that ‘volumetric-based’ BIA measures obtained in parallel, such as distance2/Rp, could be the best approach in predicting percent of body moisture, proteins, and minerals in the whole-body schema. However, serially-obtained BIA measures, such as the ratio of the reactance to resistance and the resistance adjusted for distance between electrodes, were the best fitting in predicting the compartments in the segmental schema. Validity of these results should be confirmed on humans before implementation in practice.

scholarly journals Integumentary Colour Allocation in the Stork Family (Ciconiidae) Reveals Short-Range Visual Cues for Species Recognition

Birds ◽  
2021 ◽  
Vol 2 (1) ◽  
pp. 138-146
Author(s):  
Eduardo J. Rodríguez-Rodríguez ◽  
Juan J. Negro
Keyword(s):  
Short Range ◽  
Visual Cues ◽  
Species Recognition ◽  
The Body ◽  
Whole Body ◽  
Divergent Evolution ◽  
Black And White ◽  
Extant Species ◽  
Chromatic Spectrum ◽  
Mixed Species Flocks

The family Ciconiidae comprises 19 extant species which are highly social when nesting and foraging. All species share similar morphotypes, with long necks, a bill, and legs, and are mostly coloured in the achromatic spectrum (white, black, black, and white, or shades of grey). Storks may have, however, brightly coloured integumentary areas in, for instance, the bill, legs, or the eyes. These chromatic patches are small in surface compared with the whole body. We have analyzed the conservatism degree of colouration in 10 body areas along an all-species stork phylogeny derived from BirdTRee using Geiger models. We obtained low conservatism in frontal areas (head and neck), contrasting with a high conservatism in the rest of the body. The frontal areas tend to concentrate the chromatic spectrum whereas the rear areas, much larger in surface, are basically achromatic. These results lead us to suggest that the divergent evolution of the colouration of frontal areas is related to species recognition through visual cue assessment in the short-range, when storks form mixed-species flocks in foraging or resting areas.

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