New technologies for the Tenerife Microwave Spectrometer and current status

Abstract Context.—In the current “molecular” era, the advent of technology, such as array-based platforms, systems biology, and genome-wide approaches, has made it possible to examine human cancers, including melanoma, for genetic mutations, deletions, amplification, differentially regulated genes, and epigenetic changes. Advancement in current technologies is such that one can now examine ribonucleic acid (RNA), deoxyribonucleic acid (DNA), and protein directly from the patient's own tumor. Objective.—To apply these new technologies in advancing molecular diagnostics in melanoma has historically suffered from a major obstacle, namely, the scarcity of fresh frozen, morphologically defined tumor banks, annotated with clinical information. Recently, some of the new platforms have advanced to permit utilization of formalin-fixed, paraffin-embedded (FFPE) tumor specimens as starting material. Data Sources.—This article reviews the latest technologies applied to FFPE melanoma sections, narrowing its focus on the utility of transcriptional profiling, especially for melastatin; comparative genomic hybridization; BRAF and NRAS mutational analysis; and micro ribonucleic acid profiling. Conclusion.—New molecular approaches are emerging and are likely to improve the classification of melanocytic neoplasms.

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Influential Factors for Older Users’ Acceptance of eHealth Services: an Integrated Acceptance Framework (IAF) (Preprint)

10.2196/preprints.31920 ◽

2021 ◽

Author(s):

Jiyeon Yu ◽

Angelica de Antonio ◽

Elena Villalba-Mora

Keyword(s):

Systematic Review ◽

Older Adults ◽

New Technologies ◽

Meta Analysis ◽

Health Condition ◽

Influential Factors ◽

Current Status ◽

Five Dimensions ◽

The Impact ◽

Acceptance Factors

BACKGROUND eHealth and Telehealth play a crucial role in assisting older adults who visit hospitals frequently or who live in nursing homes and can benefit from staying at home while being cared for. Adapting to new technologies can be difficult for older people. Thus, to better apply these technologies to older adults’ lives, many studies have analyzed acceptance factors for this particular population. However, there is not yet a consensual framework to be used in further development and the search for solutions. OBJECTIVE This paper presents an Integrated Acceptance Framework (IAF) for the older user’s acceptance of eHealth, based on 43 studies selected through a systematic review. METHODS We conducted a four-step study. First, through a systematic review from 2010 to 2020 in the field of eHealth, the acceptance factors and basic data for analysis were extracted. Second, we carried out a thematic analysis to group the factors into themes to propose and integrated framework for acceptance. Third, we defined a metric to evaluate the impact of the factors addressed in the studies. Last, the differences amongst the important IAF factors were analyzed, according to the participants’ health conditions, verification time, and year. RESULTS Through the systematic review, 731 studies were founded in 5 major databases, resulting in 43 selected studies using the PRISMA methodology. First, the research methods and the acceptance factors for eHealth were compared and analyzed, extracting a total of 105 acceptance factors, which were grouped later, resulting in the Integrated Acceptance Framework. Five dimensions (i.e., personal, user-technology relational, technological, service-related, environmental) emerged with a total of 23 factors. Also, we assessed the quality of the evidence. And then, we conducted a stratification analysis to reveal the more appropriate factors depending on the health condition and the assessment time. Finally, we assess which are the factors and dimensions that are recently becoming more important. CONCLUSIONS The result of this investigation is a framework for conducting research on eHealth acceptance. To elaborately analyze the impact of the factors of the proposed framework, the criteria for evaluating the evidence from the studies that have extracted factors are presented. Through this process, the impact of each factor in the IAF has been presented, in addition to the framework proposal. Moreover, a meta-analysis of the current status of research is presented, highlighting the areas where specific measures are needed to facilitate e-Health acceptance.

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Application of Artificial Intelligence in Early Gastric Cancer Diagnosis

Digestion ◽

10.1159/000519601 ◽

2021 ◽

pp. 1-7

Author(s):

Zili Xiao ◽

Danian Ji ◽

Feng Li ◽

Zhengliang Li ◽

Zhijun Bao

Keyword(s):

Artificial Intelligence ◽

Gastric Cancer ◽

New Technologies ◽

Narrow Band Imaging ◽

Daily Practice ◽

Colorectal Polyps ◽

Current Status ◽

Randomized Controlled ◽

Depth Prediction ◽

Substantial Effort

Background: With the development of new technologies such as magnifying endoscopy with narrow band imaging, endoscopists achieved better accuracy for diagnosis of gastric cancer (GC) in various aspects. However, to master such skill takes substantial effort and could be difficult for inexperienced doctors. Therefore, a novel diagnostic method based on artificial intelligence (AI) was developed and its effectiveness was confirmed in many studies. AI system using convolutional neural network has showed marvelous results in the ongoing trials of computer-aided detection of colorectal polyps. Summary: With AI’s efficient computational power and learning capacities, endoscopists could improve their diagnostic accuracy and avoid the overlooking or over-diagnosis of gastric neoplasm. Several systems have been reported to achieved decent accuracy. Thus, AI-assisted endoscopy showed great potential on more accurate and sensitive ways for early detection, differentiation, and invasion depth prediction of gastric lesions. However, the feasibility, effectiveness, and safety in daily practice remain to be tested. Key messages: This review summarizes the current status of different AI applications in early GC diagnosis. More randomized controlled trails will be needed before AI could be widely put into clinical practice.

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Application of Genomic Big Data in Plant Breeding: Past, Present, and Future

Plants ◽

10.3390/plants9111454 ◽

2020 ◽

Vol 9 (11) ◽

pp. 1454

Author(s):

Kyung Do Kim ◽

Yuna Kang ◽

Changsoo Kim

Keyword(s):

Plant Breeding ◽

Crop Production ◽

New Technologies ◽

Biological Data ◽

Genomic Research ◽

Current Status ◽

Plant Genomics ◽

New Paradigm ◽

The Past ◽

Interdisciplinary Approaches

Plant breeding has a long history of developing new varieties that have ensured the food security of the human population. During this long journey together with humanity, plant breeders have successfully integrated the latest innovations in science and technologies to accelerate the increase in crop production and quality. For the past two decades, since the completion of human genome sequencing, genomic tools and sequencing technologies have advanced remarkably, and adopting these innovations has enabled us to cost down and/or speed up the plant breeding process. Currently, with the growing mass of genomic data and digitalized biological data, interdisciplinary approaches using new technologies could lead to a new paradigm of plant breeding. In this review, we summarize the overall history and advances of plant breeding, which have been aided by plant genomic research. We highlight the key advances in the field of plant genomics that have impacted plant breeding over the past decades and introduce the current status of innovative approaches such as genomic selection, which could overcome limitations of conventional breeding and enhance the rate of genetic gain.

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Current status: new technologies for the treatment of patients with fecal incontinence

Surgical Endoscopy ◽

10.1007/s00464-014-3464-3 ◽

2014 ◽

Vol 28 (8) ◽

pp. 2277-2301 ◽

Cited By ~ 21

Author(s):

Andreas M. Kaiser ◽

Guy R. Orangio ◽

Massarat Zutshi ◽

Suraj Alva ◽

Tracy L. Hull ◽

...

Keyword(s):

Fecal Incontinence ◽

New Technologies ◽

Current Status

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Artificial intelligence and real estate - not just an evolution, a real game changer!

Journal of Property Investment and Finance ◽

10.1108/jpif-06-2020-0063 ◽

2020 ◽

Vol ahead-of-print (ahead-of-print) ◽

Author(s):

Marcelo Cajias

Keyword(s):

Artificial Intelligence ◽

Real Estate ◽

New Technologies ◽

Current Status ◽

Real Estate Industry ◽

Expiry Date ◽

Content Type ◽

The Real ◽

The Real Estate ◽

Analyse Data

PurposeDigitalisation and AI are the most intensively discussed topics in the real estate industry. The subject aims at increasing the efficiency of existing processes and the institutional side of the industry is really interested. And in some ways, this is a breakthrough. This article elaborates on the current status quo and future path of the industry.Design/methodology/approachThe real estate industry is evolving, and parts of the business are increasingly being conquered by “proptechs” and “fintechs”. They have come into real estate to stay not because they discovered inefficiencies in the way one manages and does business with real estate, but because they come with an arsenal of new technologies that can change the whole game. The article discusses a path for changing the game in real estate.Findings“location, location, location” has now evolved to “data, data, data”. However, there is one essential aspect that must be considered before the latter can become the real value creator: the ability of market players to analyse data. And this does not mean being an excellent Excel user. The near future sees a solution called Explainable Artificial Intelligence (XAI) meaning that the econometric world constructed decades ago has an expiry date.Originality/valueOne needs to delete two myths from their mind: data quantity is proportional to accurate insights and that bringing your data to a cloud will deliver you with all the insights your business needs almost immediately.

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Percutaneous Management of Malignant Biliary Strictures: Current Status and Future Directions

Digestive Disease Interventions ◽

10.1055/s-0037-1601378 ◽

2017 ◽

Vol 01 (01) ◽

pp. 036-046

Author(s):

Mohammed Attaya ◽

Hosam Attaya ◽

Ashraf Thabet

Keyword(s):

New Technologies ◽

Current Status ◽

Biliary Strictures ◽

Biliary Stents ◽

Future Directions ◽

Improve Patient Survival ◽

Percutaneous Interventions ◽

Improve Patient ◽

Transhepatic Biliary Drainage

AbstractVarious minimally invasive percutaneous interventions may be performed for the treatment and management of malignant biliary obstruction. The types of percutaneous interventions include percutaneous transhepatic biliary drainage, percutaneous cholecystostomy, and biliary stent placement. Biliary stents have undergone continued evolution in design to prolong patency, increase cost-effectiveness, improve patient survival, and quality of life. Furthermore, investigational techniques, such as radiofrequency ablation, intraluminal brachytherapy, and photodynamic therapy promise new technologies in the field of biliary intervention. This review focuses on the current status of percutaneous therapies for malignant biliary strictures and obstruction.

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Energy and Time Efficient Microwave Curing for CFRP Parts Manufactured by Filament Winding

Materials Science Forum ◽

10.4028/www.scientific.net/msf.825-826.741 ◽

2015 ◽

Vol 825-826 ◽

pp. 741-748

Author(s):

Stefan Betz ◽

Fabian Köster ◽

Vasileios Ramopoulos

Keyword(s):

New Technologies ◽

Fibre Volume ◽

Filament Winding ◽

Current Status ◽

Process Time ◽

Process Technology ◽

Volumetric Heating ◽

Microwave Curing ◽

Positive Effects ◽

Time Reduction

Process time reduction and energy/cost savings are usually in the focus of production process improvements. New technologies provide possibilities to achieve significant enhancements for relevant operation figures.Curing cycle times for CFRP manufacturing depend on several requirements: Type of resin, requested glass transition temperature, used equipment and energy source as well as sample size, weight, fibre volume ratio, fibre orientation etc. Conventional methods are mostly based on heat conduction while microwaves offer a selective and volumetric heating of the samples. Process time reduction and energy saving are the positive effects of the microwave curing technology.This paper will give an overview of the current status of this process technology not only focussing on technical aspects but also covering the process and economic effects.This work has been performed under the German BMBF project 02PJ2131, FLAME under the program Energy Efficient Light Weight Construction.

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Openness, access to government information and Caribbean governance

First Monday ◽

10.5210/fm.v11i7.1369 ◽

2006 ◽

Cited By ~ 2

Author(s):

Fay Durrant

Keyword(s):

New Technologies ◽

Virgin Islands ◽

Current Status ◽

Access To Information ◽

Cayman Islands ◽

Government Information ◽

Human Right ◽

External Pressures ◽

English Speaking ◽

The Impact

As governments worldwide move towards openness and transparency, the development of legislation to facilitate access to information is an essential requirement for modernization of the public sector and for effective governance. Access to information legislation is one way to ensure integrity in public life. Over 68 countries have approved national legislation and many are actively involved in the implementation of these laws. Globally the move to openness is supported by statements aimed at ensuring universal and equitable access to information as a basic human right. Factors influencing the approval of this legislation have included internal and external pressures from civil society, local and international press associations, and regional and international organizations. These laws mainly have an overall objective of mitigating corruption and provide the general public with the ability to request documents and other materials held by all government agencies and other agencies receiving public funds. The exemptions identified under the laws are usually based on ensuring national security. In the English–speaking Caribbean, Antigua and Barbuda, Belize, Jamaica, and Trinidad and Tobago have passed access legislation and several countries including the British Virgin Islands, Cayman Islands, and Guyana are discussing their own draft legislation. This paper assesses the main elements and current status of the legislation from global surveys including that done by Banisar in 2004, and will examine in detail the progress in implementing the access legislation in the Caribbean. The research will examine the context of access legislation, complementary legislation, information infrastructure, administrative procedures, and the impact of new technologies on access to information services.

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