Relationship of Fitness, Fatness, and Coronary-Heart-Disease Risk Factors in 12- to 13-Year-Olds

2007 ◽  
Vol 19 (1) ◽  
pp. 93-101 ◽  
Author(s):  
Non-Eleri Thomas ◽  
Stephen-Mark Cooper ◽  
Simon P. Williams ◽  
Julien S. Baker ◽  
Bruce Davies
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Disease Risk ◽  
Reactive Protein ◽  
Chd Risk ◽  
Heart Disease Risk Factors ◽  
Chd Risk Factors ◽  
Lipids And Lipoproteins

The purpose of this study was to examine relationships between aerobic fitness (AF), fatness, and coronary-heart-disease (CHD) risk factors in 12- to 13-year-olds. The data were obtained from 208 schoolchildren (100 boys; 108 girls) ages 12.9 ± 0.3 years. Measurements included AF, indices of obesity, blood pressure, blood lipids and lipoproteins, fibrinogen, homocysteine, and C-reactive protein. An inverse relationship was found between AF and fatness (p < .05). Fatness was related to a greater number of CHD risk factors than fitness was (p < .05). Further analysis revealed fatness to be an independent predictor of triglyceride and blood-pressure levels (p < .05). Our findings indicate that, for young people, fatness rather than fitness is independently related to CHD risk factors.

Relationships between hostility and physiological coronary heart disease risk factors in young adults: the moderating influence of depressive tendencies

2000 ◽  
Vol 30 (2) ◽  
pp. 381-393 ◽  
Author(s):  
N. RAVAJA ◽  
T. KAUPPINEN ◽  
L. KELTIKANGAS-JÄRVINEN
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Coronary Heart Disease ◽  
Young Adults ◽  
Heart Disease ◽  
Disease Risk ◽  
Density Lipoprotein ◽  
Lipoprotein Cholesterol ◽  
Chd Risk ◽  
Chd Risk Factors

Background. We examined whether the relationships between hostility and physiological coronary heart disease (CHD) risk factors differ as a function of depressive tendencies (DT).Methods. The participants were 672 randomly selected healthy young adults who self-reported their hostility (anger, cynicism, and paranoia) and DT. The physiological CHD risk factors studied were systolic blood pressure, diastolic blood pressure, body-mass index, serum high-density lipoprotein cholesterol, serum low-density lipoprotein cholesterol and serum triglycerides.Results. We found that hostility was negatively associated with the physiological CHD risk factors among individuals exhibiting high DT while hostility was positively associated with, or unrelated to, the physiological risk factors among individuals showing low DT. The Hostility × DT interaction explained 2 to 5% of the variance in the physiological parameters.Conclusion. The findings suggest that DT have a moderating influence on the relationships between hostility and CHD risk. Despite the established risk factor status of hostility, lack of anger and hostility, when combined with high DT, may represent the most severe exhaustion where the individual has given up. Disregard of this fact may explain some null findings in the research on hostility and CHD risk.

scholarly journals The Prevalence of Selected Modifiable Coronary Heart Disease Risk Factors in 12-Year-Old Greek Boys and Girls

2001 ◽  
Vol 13 (2) ◽  
pp. 173-184 ◽  
Author(s):  
Constantin Bouziotas ◽  
Yiannis Koutedakis ◽  
Ruth Shiner ◽  
Yiannis Pananakakis ◽  
Vasiliki Fotopoulou ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Energy Expenditure ◽  
Energy Intake ◽  
Cardiorespiratory Fitness ◽  
Disease Risk ◽  
The Body ◽  
Chd Risk ◽  
Chd Risk Factors

The prevalence of 14 selected modifiable coronary heart disease (CHD) risk factors was determined in randomly selected adolescent boys (n = 117) and girls (n = 93) from provincial Greece. Based on published criteria thresholds for CHD, 45% of boys and 50% of girls exhibited three or more risk factors with time spent on “vigorous” activities, low cardiorespiratory fitness and fatness being among the most frequent in both sexes. Stronger associations were found between cardiorespiratory fitness and time spent on “vigorous” rather than “moderate-to-vigorous” activities in both boys and girls. Regression analysis indicated that energy expenditure (P < .01) in boys and energy expenditure (P < .05) and energy intake (P < .01) in girls could alone explain about 60% of the body-fat related findings in either group. Broadly based primary prevention strategies aimed at children should concentrate on reducing the overall energy intake and increasing the time spent on “vigorous” activities if future Greek adult CHD mortality is to be reduced.

scholarly journals The Reversion of DNA Methylation at Coronary Heart Disease Risk Loci in Response to Prevention Therapy

Processes ◽  
2021 ◽  
Vol 9 (4) ◽  
pp. 699
Author(s):  
Willem Philibert ◽  
Allan M. Andersen ◽  
Eric A. Hoffman ◽  
Robert Philibert ◽  
Meeshanthini Dogan
Keyword(s):  
Risk Factors ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Disease Risk ◽  
Methylation Status ◽  
Digital Pcr ◽  
Response To Treatment ◽  
Chd Risk ◽  
Chd Risk Factors ◽  
The Relationship

Coronary heart disease (CHD) is preventable, but the methods for assessing risk and monitoring response rely on imprecise lipid-based assessments. Recently, we have shown that an integrated genetic–epigenetic test that includes three methylation-sensitive digital PCR assays predicts 3-year risk for incident CHD better than lipid-based methods. However, whether methylation sites change in response to therapies that alter CHD risk is not known. Therefore, we assessed methylation at these three incident CHD-related sites in DNA from 39 subjects before and after three months of biochemically verified smoking cessation, then analyzed the relationship between change in methylation at each of the sites to the change in smoking intensity as assessed by cg05575921 methylation. We found that, in those who quit smoking, methylation change at one CHD risk marker (cg00300879) was significantly associated with change in cg05575921 methylation (p < 0.04). We conclude that changes in incident CHD-related methylation occur within three months of cessation of smoking, a major risk factor for CHD. This suggests that the effectiveness of treatment of other CHD risk factors, such as high cholesterol, may be similarly quantifiable using epigenetic approaches. Further studies to determine the relationship of changes of methylation status in response to treatment of other CHD risk factors are indicated.

A Healthy Nordic diet score and risk of incident coronary heart disease among men: the Kuopio Ischaemic Heart Disease Risk Factor Study

2021 ◽  
pp. 1-23
Author(s):  
Hanna-Mari Tertsunen ◽  
Sari Hantunen ◽  
Tomi-Pekka Tuomainen ◽  
Jukka T. Salonen ◽  
Jyrki K. Virtanen
Keyword(s):  
Risk Factors ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Carotid Atherosclerosis ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Nordic Diet ◽  
Chd Risk ◽  
Chd Risk Factors ◽  
Diet Score

Abstract Healthy Nordic diet has been beneficially associated with coronary heart disease (CHD) risk factors, but few studies have investigated risk of developing CHD. We investigated the associations of healthy Nordic diet with major CHD risk factors, carotid atherosclerosis, and incident CHD in middle-aged and older men from eastern Finland. A total of 1981 men aged 42-60 years and free of CHD at baseline in 1984-1989 were investigated. Diet was assessed with 4-d food recording and the healthy Nordic diet score was calculated based on the Baltic Sea Diet Score. Carotid atherosclerosis was assessed by ultrasonography of the common carotid artery intima-media thickness in 1053 men. Analysis of covariance and Cox proportional hazards regression analyses were used for analyses. Healthy Nordic diet score associated with lower serum C-reactive protein concentrations (multivariable-adjusted extreme-quartile difference 0.69 mg/L, 95% confidence interval 0.15-1.22 mg/L), but not with serum lipid concentrations, blood pressure, or carotid atherosclerosis. During the average follow-up of 21.6 years (SD 8.3 years), 407 men had a CHD event, of which 277 were fatal. The multivariable-adjusted hazard ratios (95% confidence interval) in the lowest vs. the highest quartile of the healthy Nordic diet score were 1.10 (0.85-1.45) for any CHD event (P-trend 0.429) and 1.38 (0.95-2.00) (P-trend 0.119) for fatal CHD event. We did not find evidence that adherence to a healthy Nordic diet would be associated with a lower risk of CHD or with carotid atherosclerosis or major CHD risk factors, except for an inverse association with serum C-reactive protein concentrations.

Sign in / Sign up

Export Citation Format

Share Document