In Vivo Efficacy of Ellagic Acid against Candida albicans in a Drosophila melanogaster Infection Model
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ABSTRACT The aim of this study was to evaluate the antifungal activity and the toxicity of ellagic acid (EA) using a Drosophila melanogaster model. Candida albicans bacteria were inoculated into Toll heterozygous flies. Survival curves were obtained for the evaluation of the antimicrobial effect and toxicity of EA. A protective effect of EA against fungal infection in Drosophila melanogaster was observed at nontoxic concentrations. This study showed that EA is a promising tool for the treatment of candidiasis.
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2014 ◽
Vol 58
(4)
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pp. 2344-2355
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2014 ◽
Vol 59
(2)
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pp. 1341-1343
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2012 ◽
Vol 57
(1)
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pp. 445-451
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2015 ◽
Vol 59
(4)
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pp. 2113-2121
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