GyrB mutations in Staphylococcus aureus strains resistant to cyclothialidine, coumermycin, and novobiocin.
1996 ◽
Vol 40
(4)
◽
pp. 1060-1062
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Keyword(s):
The sequence of the gyrase B subunit gene from Staphylococcus aureus strains resistant to the gyrase B subunit inhibitors cyclothialidine, coumermycin, and novobiocin has been determined. The residues altered in the resistant gyrase B subunits map to the ATP-binding region, suggesting that the drugs inhibit ATP binding and hydrolysis. The pattern of cross-resistances indicates that the detailed binding mode of the compounds differs.
1987 ◽
Keyword(s):
2016 ◽
Vol 49
(3)
◽
pp. 394-401
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2000 ◽
Vol 97
(15)
◽
pp. 8675-8680
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2010 ◽
Vol 1797
(10)
◽
pp. 1768-1774
1993 ◽
Vol 268
(28)
◽
pp. 20930-20936
2021 ◽
Vol 77
(5)
◽
pp. 587-598