scholarly journals Characterization of the cytoplasmic filament protein gene (cfpA) of Treponema pallidum subsp. pallidum.

1996 ◽  
Vol 178 (11) ◽  
pp. 3177-3187 ◽  
Author(s):  
Y You ◽  
S Elmore ◽  
L L Colton ◽  
C Mackenzie ◽  
J K Stoops ◽  
...  
1998 ◽  
Vol 66 (6) ◽  
pp. 2999-3002 ◽  
Author(s):  
Shermalyn R. Greene ◽  
Lola V. Stamm

ABSTRACT The nucleotide sequence of the Treponema pallidum mcp2gene was determined. mcp2 encodes a 45.8-kDa protein whose deduced amino acid sequence has significant homology with the C-terminal region of bacterial methyl-accepting chemotaxis proteins (MCPs). The Mcp2 N terminus lacks the hydrophobic transmembrane regions present in most MCPs. An Mcp2 fusion protein was strongly reactive with antibody (HC23) to the highly conserved domain of MCPs and with rabbit syphilitic serum. Antibody HC23 reacted with six T. pallidum proteins, including a 45-kDa protein that may correspond to Mcp2. This protein was present in the aqueous phase from T. pallidum cells that were solubilized with Triton X-114 and phase partitioned.


2020 ◽  
Vol 2 (2) ◽  
Author(s):  
Nchowela Guido

Introduction: Syphilis is one of several diseases that can be transmitted during pregnancy and childbirth, which can lead to complications during pregnancy and in the newborn. This is especially so when the pregnant woman is not diagnosed or treated properly and in a timely manner. Methodology: Data from 262 pregnant women prospectively included, aged 18-41years, attended at the Ponta Gêa Health Centre for antenatal clinics has been analyzed from January to September of 2016. In the prospective study, a rapid treponemal and a non-treponemal test were performed. A structured questionnaire was used to collect socio demographic and clinical variables, which was developed from the literature review. Results: The prevalence of active syphilis was 11.8%; the majority of reactive pregnant women were aged 18-25years (55.4%), (61.3%) of pregnant women were treated with doses below those recommended; only a small number of the partners were treated successfully. The highest seroprevalence of syphilis was found in housewives (77%), in those who attended primary education (71.6%) in those who had a monthly income of 1000- 3000 MZN (70.3%), in those with two or more pregnancies (55.7%) and living with someone has husband and wife (63.5%). The syphilis/HIV co-infection rate was high. Conclusion: According to the results obtained in this study, urgent measures are needed to assess the problems encountered and to improve the screening approach, treatment and monitoring of syphilis during pregnancy in order to prevent the cases of congenital syphilis.


2013 ◽  
Vol 99 (2) ◽  
pp. 379-382 ◽  
Author(s):  
Irshad M. Sulaiman ◽  
Patricia Torres ◽  
Steven Simpson ◽  
Khalil Kerdahi ◽  
Ynes Ortega

1995 ◽  
Vol 270 (24) ◽  
pp. 14733-14741 ◽  
Author(s):  
Marius Sudol ◽  
Peer Bork ◽  
Aaron Einbond ◽  
Kumar Kastury ◽  
Teresa Druck ◽  
...  
Keyword(s):  

2007 ◽  
Vol 35 (2) ◽  
pp. 145-152 ◽  
Author(s):  
Yong-Mei Bao ◽  
Jian-Fei Wang ◽  
Ji Huang ◽  
Hong-Sheng Zhang

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