Twelve-Transmembrane-Segment (TMS) Version (ΔTMS VII-VIII) of the 14-TMS Tet(L) Antibiotic Resistance Protein Retains Monovalent Cation Transport Modes but Lacks Tetracycline Efflux Capacity
2001 ◽
Vol 183
(8)
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pp. 2667-2671
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Keyword(s):
ABSTRACT A “Tet(L)-12” version of Tet(L), a tetracycline efflux protein with 14 transmembrane segments (TMS), was constructed by deletion of two central TMS. Tet(L)-12 catalyzed Na+/H+antiport and antiport with K+ as a coupling ion as well as or better than wild-type Tet(L) but exhibited no tetracycline-Me2+/H+ antiport inEscherichia coli vesicles.
1999 ◽
Vol 181
(9)
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pp. 2710-2718
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Keyword(s):
1997 ◽
Vol 41
(12)
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pp. 2699-2704
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2004 ◽
Vol 186
(16)
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pp. 5281-5291
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2002 ◽
Vol 68
(1)
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pp. 440-443
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Keyword(s):
2021 ◽
Keyword(s):
2002 ◽
Vol 283
(2)
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pp. C512-C520
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