scholarly journals Magmatic sill formation during dike opening

Geology ◽  
2021 ◽  
Author(s):  
Zhonglan Liu ◽  
W. Roger Buck
Keyword(s):  
Viscoelastic Medium ◽  
Average Density ◽  
Spreading Center ◽  
Time Interval ◽  
Two Dimensional ◽  
Short Term ◽  
Magma Intrusion ◽  
Spreading Ridges ◽  
Plate Spreading

The origin of horizontal magma-filled sills is disputed, particularly for extensional settings where the opening of vertical dikes is the predicted mode of magma intrusion. We simulate long-term extension followed by short-term dike opening in a two-dimensional viscoelastic medium representing a plate spreading center. We show that dike opening in extensionally stressed lithosphere can reduce sublithospheric vertical stresses enough for sill opening given three conditions: (1) the Maxwell time of the asthenosphere is <5× the time interval between dike episodes; (2) the average density of the lithosphere is not much greater than the magma density; and (3) the depth of an axial valley is smaller than a few hundred meters. This mechanism explains the presence of sills along much of the axis of faster-spreading ridges and their absence along slower-spreading centers where thick dense lithosphere and/or sizeable axial valleys exist.

scholarly journals Time Interval to Biochemical Failure as a Surrogate End Point in Locally Advanced Prostate Cancer: Analysis of Randomized Trial NRG/RTOG 9202

2019 ◽  
Vol 37 (3) ◽  
pp. 213-221 ◽  
Author(s):  
James J. Dignam ◽  
Daniel A. Hamstra ◽  
Herbert Lepor ◽  
David Grignon ◽  
Harmar Brereton ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Randomized Trial ◽  
Locally Advanced ◽  
Biochemical Failure ◽  
Mediating Effect ◽  
Time Interval ◽  
Short Term ◽  
End Points ◽  
End Point

Background In prostate cancer, end points that reliably portend prognosis and treatment benefit (surrogate end points) can accelerate therapy development. Although surrogate end point candidates have been evaluated in the context of radiotherapy and short-term androgen deprivation (AD), potential surrogates under long-term (24 month) AD, a proven therapy in high-risk localized disease, have not been investigated. Materials and Methods In the NRG/RTOG 9202 randomized trial (N = 1,520) of short-term AD (4 months) versus long-term AD (LTAD; 28 months), the time interval free of biochemical failure (IBF) was evaluated in relation to clinical end points of prostate cancer–specific survival (PCSS) and overall survival (OS). Survival modeling and landmark analysis methods were applied to evaluate LTAD benefit on IBF and clinical end points, association between IBF and clinical end points, and the mediating effect of IBF on LTAD clinical end point benefits. Results LTAD was superior to short-term AD for both biochemical failure (BF) and the clinical end points. Men remaining free of BF for 3 years had relative risk reductions of 39% for OS and 73% for PCSS. Accounting for 3-year IBF status reduced the LTAD OS benefit from 12% (hazard ratio [HR], 0.88; 95% CI, 0.79 to 0.98) to 6% (HR, 0.94; 95% CI, 0.83 to 1.07). For PCSS, the LTAD benefit was reduced from 30% (HR, 0.70; 95% CI, 0.52 to 0.82) to 6% (HR, 0.94; 95% CI, 0.72 to 1.22). Among men with BF, by 3 years, 50% of subsequent deaths were attributed to prostate cancer, compared with 19% among men free of BF through 3 years. Conclusion The IBF satisfied surrogacy criteria and identified the benefit of LTAD on disease-specific survival and OS. The IBF may serve as a valid end point in clinical trials and may also aid in risk monitoring after initial treatment.

scholarly journals Remember like humans

2017 ◽  
Vol 14 (1) ◽  
pp. 172988141769231 ◽  
Author(s):  
Ning An ◽  
Shi-Ying Sun ◽  
Xiao-Guang Zhao ◽  
Zeng-Guang Hou
Keyword(s):  
Short Term Memory ◽  
Three Dimensional ◽  
Sensory Memory ◽  
Long Term Memory ◽  
Observation Model ◽  
Two Dimensional ◽  
Short Term ◽  
Term Memory ◽  
Memory Register

Visual tracking is a challenging computer vision task due to the significant observation changes of the target. By contrast, the tracking task is relatively easy for humans. In this article, we propose a tracker inspired by the cognitive psychological memory mechanism, which decomposes the tracking task into sensory memory register, short-term memory tracker, and long-term memory tracker like humans. The sensory memory register captures information with three-dimensional perception; the short-term memory tracker builds the highly plastic observation model via memory rehearsal; the long-term memory tracker builds the highly stable observation model via memory encoding and retrieval. With the cooperative models, the tracker can easily handle various tracking scenarios. In addition, an appearance-shape learning method is proposed to update the two-dimensional appearance model and three-dimensional shape model appropriately. Extensive experimental results on a large-scale benchmark data set demonstrate that the proposed method outperforms the state-of-the-art two-dimensional and three-dimensional trackers in terms of efficiency, accuracy, and robustness.

scholarly journals Systema Temporis: A Time-Based Dimensional Framework for Consciousness and Cognition

2019 ◽  
Author(s):  
Lachlan Kent ◽  
George Van Doorn ◽  
Britt Klein
Keyword(s):  
Time Perception ◽  
Dimensional Structure ◽  
Two Dimensional ◽  
Dimensional Approach ◽  
Short Term ◽  
Hierarchical Framework ◽  
Time Consciousness ◽  
Emotion And Memory ◽  
Definition Of

This study uses a combined categorical-dimensional approach to depict a hierarchical framework for consciousness similar to, and contiguous with, factorial models of cognition (cf., intelligence). On the basis of the longstanding definition of time consciousness, the analysis employs a dimension of temporal extension, in the same manner that psychology has temporally organised memory (i.e., short-term, long-term, and long-lasting memories). By defining temporal extension in terms of the structure of time perception at short timescales (< 100 s), memory and time consciousness are proposed to fit along the same logarithmic dimension. This suggests that different forms of time consciousness (e.g., experience, wakefulness, and self-consciousness) are embedded within, or supported by, the ascending timescales of different modes of memory (i.e., short-term, long-term, etc.). A secondary dimension is also proposed to integrate higher-order forms of consciousness/emotion and memory/cognition. The resulting two-dimensional structure accords with existing theories of cognitive and emotional intelligence.

scholarly journals EFFECTS OF WELDING PARAMETERS, TIME INTERVAL AND PREHEATING ON RESIDUAL STRESS AND DISTORTION OF JOINING ST52 STIFFENER RING IN AN AISI 4130 TUBULAR SHELL

2020 ◽  
Vol 3 (1) ◽  
pp. 11-15
Author(s):  
Alireza M. Haghighi ◽  
Farhad S. Samani
Keyword(s):  
Residual Stress ◽  
Welding Current ◽  
Welding Parameters ◽  
Time Interval ◽  
Negative Effects ◽  
Short Term ◽  
Welding Line ◽  
Aisi 4130 ◽  
Comparison Of The Results

Stiffener rings and stringers are used commonly in offshore and aerospace structures. Welding the stiffener to the structure causes the appearance of residual stress and distortion that leads to short-term and long-term negative effects. Residual stress and distortion of welding have destructive effects such as deformation, brittle fracture, and fatigue of the welded structures. This paper aims to investigate the effects of preheating, time interval and welding parameters such as welding current and speed on residual stress and distortion of joining an ST52-3N (DIN 1.0570) T-shape stiffener ring to an AISI 4130 (DIN 1.7218) thin-walled tubular shell by eleven pairs of welding line in both sides of the ring by means of finite element method (FEM). Results in tangent (longitudinal), axial and radial directions have been compared and the best welding methods proposed. After the comparison of the results, simultaneous welding both sides of the ring with preheating presented as the best method with less distortion and residual stresses among the studied conditions. The correctness of the FEM confirmed by the validation of the results.

Intraindividual variation of glycohemoglobin: implications for interpretation and analytical goals

1993 ◽  
Vol 39 (11) ◽  
pp. 2305-2308 ◽  
Author(s):  
G Phillipou ◽  
P J Phillips
Keyword(s):  
Weighted Average ◽  
Affinity Column ◽  
Time Interval ◽  
Short Term ◽  
Intraindividual Variation ◽  
Clinical Control ◽  
Significant Difference ◽  
Patients With Diabetes ◽  
Analytical Imprecision

Abstract Intraindividual variation (CVi) for glycohemoglobin (GHb) was estimated from serial measurements in patients with diabetes in either stable or variable clinical control. GHb determinations were performed by an affinity column procedure with an analytical imprecision of 4.9% (weighted average; GHb 8.2-14.7%). Within the groups of patients, both a short- (28-32 days) and long-term (approximately 85 days) sampling protocol was used. The derived CVi for each category was 4.2% (n = 16, stable, short-term), 7.1% (n = 23, stable, long-term), 5.1% (n = 13, variable, short-term), and 9.8% (n = 21, variable, long-term). The mean GHb within each category was similar (approximately 11%), and there was no statistically significant difference in GHb values between categories. The results establish that the CVi for GHb is affected by both clinical control and the sampling time interval. These findings have important implications for the estimation of significant differences between serial GHb measurements and the setting of appropriate analytical precision goals.

Taking advantage of time-averaging

Paleobiology ◽  
1999 ◽  
Vol 25 (2) ◽  
pp. 226-238 ◽  
Author(s):  
Thomas Olszewski
Keyword(s):  
Temporal Resolution ◽  
Full Range ◽  
Exponential Model ◽  
Published Data ◽  
Time Interval ◽  
Time Averaging ◽  
Short Term ◽  
Constant Rate ◽  
Rapid Destruction

AbstractOne of the major obstacles in dealing with any form of data derived from fossils is the effects of time-averaging, which are the result of mixing the remains of organisms that did not live contemporaneously. Although this process results in loss of temporal resolution, it also serves to filter out short-term variations. Temporal resolution of a collection depends not only on the range of fossil ages, but also on their frequency distribution. Previous studies of marine molluscs indicate that most shells in an accumulation are relatively young. Such a distribution of shell ages can be fit by an exponential curve (assuming both a constant probability of shell loss and a constant rate of shell addition), which implies that 90% of the shells were added during the last 50% of the time interval represented by the collection. That is to say, differences between two collections can be discerned even if they overlap 50% in time, because the proportion of shells with shared ages is only 10%. Applying the exponential model to previously published data suggests that long-term rates of destruction are controlled by how frequently shells from the taphonomically active zone are re-exposed to rapid destruction. To take advantage of the “noise-filtering” property of time-averaging, samples need to be large enough to catch the full range of environmental variation recorded by an accumulation. A simple probability formula indicates that samples of easily achievable size can give satisfactory time-averaged results depending on the level of confidence and sampling density defined by the researcher.

scholarly journals Novelty at second glance: A critical appraisal of the novel-object paradigm based on meta-analysis

2020 ◽  
Author(s):  
E. Takola ◽  
E. T. Krause ◽  
C. Müller ◽  
H. Schielzeth
Keyword(s):  
Individual Differences ◽  
Standardized Testing ◽  
Time Interval ◽  
The Novel ◽  
Food Label ◽  
Short Term ◽  
Novel Object ◽  
Novel Objects ◽  
Individual Consistency

ABSTRACTThe study of consistent individual differences in behaviour has become an important focus in research on animal behaviour. Behavioural phenotypes are typically measured through standardized testing paradigms and one frequently used paradigm is the novel object test. In novel object tests, animals are exposed to new (unknown) objects and their reaction is quantified. When repeating trials to assess the temporal consistency of individual differences, researchers face the dilemma of whether to use the same or different ‘novel’ objects, since the same stimulus can result in habituation, while exposure to different objects can result in context-dependent responses. We performed a quantitative assessment of 254 effect sizes from 113 studies on novel-object trials to evaluate the properties of this testing paradigm, in particular the effect of object novelty and time interval between novel-object trials on estimates of individual consistency. We found an increase of sample sizes and an increase of estimates of repeatabilities with time. The vast majority of short-term studies (<one month) used different novel objects, while long-term studies (>one month) used either the same or different novel objects about equally often. The average estimate for individual consistency was r = 0.47 (short-term r = 0.52, long-term r = 0.44). Novelty, time interval between trials and their interaction together explained only 3% of the total heterogeneity. Overall, novelobject trials reliably estimate individual differences in behaviour, but results were very heterogeneous even within the same study species, suggesting susceptibility to unknown details in testing conditions. Most studies that measure novel-object responses in association with food label the trait as neophobia, while novel-object trials in a neutral context are labelled variously as boldness/shyness, exploratory behaviour or neophobia/neophilia. Neophobia/neophilia is also the term most specific to novel object presentations. To avoid ambiguity, we suggest object neophobia/neophilia as the most specific label for novel-object responses.

scholarly journals THE APPLICATION OF CYCLOSTRATIGRAPHY AND ASTROCHRONOLOGY IN THE NEOGENE MARINE DEPOSITS OF EASTERN MEDITERRANEAN: METOCHIA SECTION (GAVDOS ISLAND)

2006 ◽  
Vol 39 (1) ◽  
pp. 17
Author(s):  
A. Antonarakou ◽  
H. Drinia ◽  
F. Pomoni-Papaioannou
Keyword(s):  
Eastern Mediterranean ◽  
Climatic Changes ◽  
Sea Surface ◽  
Time Interval ◽  
Short Term ◽  
Solar Insolation ◽  
Marine Deposits ◽  
Long Term Trend

Significant lithostratigraphical and micropaleontological signatures, of Milankovitchscale climatic changes are recorded in Miocene deep-sea sediments. As a case study, the Metochia Section, in Gavdos Island, which covers the time interval from 9.7 to 6.6 Ma, is used. This study emphasizes the sedimentological and micropaleontological characteristics of the section, attributed to Milankovitch-scale climatic changes. The short-term variations in climate and faunal composition are related to precession- controlled sedimentary cycles and the long-term trend in climate is related to eccentricity and obliquity cycles. Regional changes in sea surface temperature in combination with variations of solar insolation have caused the cyclical astronomical controlled pattern of Globorotalia species.

scholarly journals Evaluating Factors Affecting the Time Interval Between Propofol Injection and Induction of Electro-convulsion and Relationship Between These Factors and Duration of Convulsion

2021 ◽  
Vol 11 (4) ◽  
Author(s):  
Alireza Haji Seyed Javadi ◽  
Ehsan Najafian ◽  
Hamid Kayalha ◽  
Ali Akbar Shafikhani
Keyword(s):  
Clinical Severity ◽  
Seizure Threshold ◽  
Current Evidence ◽  
P Value ◽  
Time Interval ◽  
Short Term ◽  
Seizure Duration ◽  
Factors Affecting ◽  
The Relationship

Background: Current evidence on the effect of anesthetic-ECT time interval (AETI) is controversial. This study aimed to investigate the factors affecting the time interval between propofol injection and electro-convulsion induction and the relationship between these factors and the duration of convulsion. Methods: In this study, 102 patients (616 sessions of ECT) were studied. Demographic and clinical data (age, gender, receiving or not receiving medications that affected the seizure threshold, the total number of ECT sessions, clinical severity of admission scores, clinical diagnosis, propofol dose, seizure duration, and AETI) were collected in special forms and analyzed by appropriate statistical methods. Results: Sessions with long-term AETI had longer seizure time than sessions with short-term AETI (33.47 ± 8.46 vs. 28.68 ± 9.74, P value < 0.05). The duration of seizures was significantly longer in the group with long AETI in sessions 1, 2, and 4 than in the other group (P value < 0.05). There was a significant relationship between the duration of seizures and propofol dose, AETI, and receiving drugs effective in the seizure threshold (P value < 0.05). Conclusions: The results showed that increasing AETI and injecting a lower dose of propofol to induce anesthesia would increase the duration of seizures. Also, taking medications that would affect the seizure threshold reduces the duration of seizures.

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