scholarly journals Management of a case of orbital lymphangioma presenting in adulthood with negative-pressure aspiration and bleomycin injection

2019 ◽  
Vol 12 (6) ◽  
pp. e227697
Author(s):  
Sagnik Sen ◽  
Pallavi Singh ◽  
Mandeep S Bajaj ◽  
Nripen Gaur
Keyword(s):  
Visual Acuity ◽  
Negative Pressure ◽  
Surgical Excision ◽  
Sudden Onset ◽  
Age Group ◽  
Adult Age ◽  
Finger Counting ◽  
Contrast Enhanced ◽  
Retrobulbar Space

We hereby report a case of a 55-year-old woman, with complaints of sudden onset outward protrusion of left eye progressing over 2 months, along with pain and loss of vision. Visual acuity in the affected eye was light perception only. On imaging, a well-defined solitary cystic lesion was noted in the retrobulbar space, which showed no enhancement on contrast-enhanced MRI. We performed fluid aspiration from the cyst under negative pressure and injected bleomycin as a sclerosant, without attempting a surgical excision. The proptosis reduced visibly, and after a week, visual acuity improved to finger counting at 1 m. At the 6 months follow-up, the patient did not show any recurrence of proptosis. This report highlights the importance of sclerosant therapy without the need for surgical excision in managing macrocystic lymphangiomas in adult age group.

scholarly journals Primary Corneoscleral Cyst in a Pediatric Patient

2017 ◽  
Vol 8 (2) ◽  
pp. 425-428 ◽  
Author(s):  
Charudutt Kalamkar ◽  
Amrita Mukherjee
Keyword(s):  
Visual Acuity ◽  
Surgical Excision ◽  
Corneal Opacity ◽  
Age Group ◽  
Pediatric Age ◽  
Visual Axis ◽  
Pediatric Age Group ◽  
Eye Examination ◽  
Scleral Graft

Purpose: Primary corneoscleral cyst is a rare disease occurring in the pediatric age group. We report a case of corneoscleral cyst with visual diminution. Methods: We conducted a case report. Results: A 7-year-old girl presented with corneal opacity in the left eye. Examination revealed a corneoscleral cyst. The corneal part of the cyst involved visual axis. Surgical excision with a scleral graft was performed, leading to an improvement in visual acuity. No recurrences were observed until the last follow-up at 18 months. Conclusions: Corneoscleral cyst should be considered in the differential diagnosis of cystic ocular surface disorders in the pediatric age group.

scholarly journals Congenital agenesis of the lung: A case report and literature review

2017 ◽  
Vol 1 ◽  
pp. 12
Author(s):  
Rajesh Gupta ◽  
Anjali Gupta ◽  
Aradhana Singh
Keyword(s):  
Respiratory Distress ◽  
Sudden Onset ◽  
Age Group ◽  
X Ray ◽  
Adult Age ◽  
Foreign Body Bronchus ◽  
Group A ◽  
Congenital Agenesis ◽  
The Right

Developmental malformations of the lung are common but complete agenesis of the lung is quite rare and usually the patients presented are in early childhood; though according to literature, a few cases have come to light even in the adult age group. A 10-month-old male child presented with a sudden onset of respiratory distress with opacity of the right hemithorax on X-ray, raising suspicion of foreign body bronchus. Subsequent CT scans and bronchoscopy revealed agenesis of the right lung. Patient was managed conservatively and his parents were counseled about the anomaly. The child is doing well and is in a regular follow-up with us. Agenesis of the lung should be suspected in children with recurrent respiratory distress with opacity of the hemithorax on X-ray and herniation of the opposite lung across the mediastinum.

Orbital Hydatid Cyst: An Interventional Case Series

2021 ◽  
Vol 37 (2) ◽  
Author(s):  
Tajamul Khan ◽  
Ibrar Hussain ◽  
Zaman Shah
Keyword(s):  
Visual Acuity ◽  
Hydatid Cyst ◽  
Teaching Hospital ◽  
Case Series ◽  
Surgical Excision ◽  
P Value ◽  
Presumptive Diagnosis ◽  
Female Ratio ◽  
Orbital Imaging

Purpose:  To find out the demographics, presentation, and outcome of surgical treatment in patients of orbital hydatid cyst. Study Design:  Interventional case series. Place and Duration of Study:  Khyber Teaching Hospital Peshawar, Pakistan from 2009 to 2019. Methods:  This study included 11 patients with orbital hydatid cyst who presented in Khyber Teaching Hospital, Peshawar. Detailed history, ocular examination and Orbital imaging (Ophthalmic B-Scan, CT scan and/or MRI) was performed. The patients underwent Orbitotomy, cyst extirpated and sent for histopathology. Albendazole was given to the patients for 12 weeks after surgery. The preoperative and postoperative data until last follow-up was analyzed. Results:  Male to Female ratio was 5:6 and the mean age of the patients was 18.17 ± 17.4 years. Mean amount of proptosis was 26.27 ± 2.05mm and visual acuity was 0.23 ± 0.33 decimal in the affected eye at presentation. Eight patients (72.8%) had Relative Afferent Pupillary Defect with swollen discs. After imaging studies, presumptive diagnosis of hydatid cyst was made. Histopathology confirmed the diagnosis of hydatid cyst in all cases. Mean proptosis at the last follow up improved to 19.04 ± 1.45mm (P value = 0.00) and visual acuity to 0.47 ± 0.22 decimals (P value = 0.048). Only one patient (9.1%) had an associated hydatid cyst in the lung. There was no recurrence until last follow-up. Conclusion:  Hydatid cyst should be considered in differential diagnosis of proptosis in patients under 20. Surgical excision followed by a course of oral Albendazole is effective for the treatment of orbital hydatid cyst. Key Words:  Orbital hydatid cyst, Proptosis, Orbitotomy.

scholarly journals Myxoid liposarcoma of small bowel presenting with intussusception and obstruction: A case report

2022 ◽  
pp. 519-521
Author(s):  
Mohd Monis ◽  
Divyashree Koppal ◽  
Aiman Ibbrahim ◽  
Zeeshan Nahid
Keyword(s):  
Small Bowel ◽  
Intestinal Obstruction ◽  
Leading Edge ◽  
Surgical Excision ◽  
Myxoid Liposarcoma ◽  
Histopathological Analysis ◽  
Contrast Enhanced ◽  
Well Differentiated ◽  
Enhanced Computed Tomography

Gastrointestinal liposarcomas are extremely rare with the most common reported morphological subtype being dedifferentiated liposarcoma and well-differentiated liposarcoma. These tumors are rarely diagnosed preoperatively and diagnosis is only confirmed on histopathological analysis. Treatment of gastrointestinal liposarcomas consists of surgical excision with widely negative margins followed by post-operative irradiation and close follow-up. We report an exceedingly rare case of myxoid liposarcoma of the small bowel (ileum) presenting with an unusual presentation with intussusception and intestinal obstruction. A 42-year-old male presented to the emergency department with features of intestinal obstruction. Contrast-enhanced computed tomography abdomen revealed ileo-ileal intussusception with an endoluminal soft-tissue lesion at the leading edge. The patient was taken for surgical intervention and the involved segment of the bowel along with the lesion was resected and re-anastomosis done. Histological sections of the mass along with immunohistochemistry suggested the pathological diagnosis of myxoid liposarcoma.

Role of contrast-enhanced spectral mammography in the post biopsy management of B3 lesions: Preliminary results

2018 ◽  
Vol 105 (5) ◽  
pp. 378-387 ◽  
Author(s):  
Giulia Bicchierai ◽  
Jacopo Nori ◽  
Diego De Benedetto ◽  
Cecilia Boeri ◽  
Ermanno Vanzi ◽  
...  
Keyword(s):  
Breast Imaging ◽  
Surgical Excision ◽  
Surgical Biopsy ◽  
Predictive Values ◽  
Contrast Enhanced ◽  
B3 Lesions ◽  
Malignant Lesions ◽  
Sensitivity Specificity

PurposeTo evaluate the role of contrast-enhanced spectral mammography (CESM) in the post biopsy management of breast lesions classified as lesions of uncertain malignant potential (B3) by core needle biopsy and vacuum-assisted biopsy (VAB).MethodsThe local ethics committee approved this retrospective study and for this type of study formal consent is not required. A total of 42 B3 lesions in 40 women aged 41–77 years were included in our study. All patients underwent CESM 2–3 weeks after the biopsy procedure and surgical excision was subsequently performed within 60 days of the CESM procedure. Three radiologists reviewed the images independently. The results were then compared with histologic findings.ResultsThe sensitivity, specificity, and positive and negative predictive values for confirmed demonstration of malignancy at CESM were 33.3%, 87.2%, 16.7%, and 94.4% for reader 1; 66.7%, 76.9%, 18.2%, and 96.7% for reader 2; 66.7%, 74.4%, 16.7%, and 96.7% for reader 3. Overall agreement on detection of malignant lesions using CESM among readers ranged from moderate to substantial (κ = .451–.696), for categorization of BPE from moderate to substantial (κ = .562–.711), and for evaluation of lesion intensity enhancement from fair to moderate (κ = .346–.459).ConclusionIn cases of Breast Imaging Reporting and Data System (BI-RADS) 1, BI-RADS 2, or BI-RADS 3 results at CESM, follow-up or VAB rather than surgical biopsy might be performed.

scholarly journals The Comparison of Visual Acuity After Congenital Cataract Surgery between Children ≤2 Years and >2-17 Years

2020 ◽  
Vol 3 (2) ◽  
pp. 70
Author(s):  
Adam Surya Romadhon ◽  
Joni Susanto ◽  
Rozalina Loebis
Keyword(s):  
Visual Acuity ◽  
Congenital Cataract ◽  
Cross Sectional Study ◽  
Study Data ◽  
Age Group ◽  
Cross Sectional ◽  
Group 2 ◽  
Congenital Surgery ◽  
Better Than

Introduction: Congenital cataract is turbidity occurs in eye lens that present at birth or immediately after. We aim to find out visual acuity after congenital surgery between children under 2 years old and 2-17 years old after following up 3, 6, 12 months.Methods: This was a cross-sectional study. Data were gathered from medical record of congenital cataract aged ≤2 years and >2-17 years including age of surgery, frequency of eyes, sex, laterality, and visual acuity of patients with best corrected visual acuity (BCVA). All data analyzed using Mann-Whitney test.Results: 41 children (67 affected eyes) in which 45 eyes that were operated at aged ≤2 years and 22 eyes were operated at aged >2-17 years. There was average difference of visual acuity between age group of ≤2 years and >2-17 years while following-up 3 months (1.60 ± 0.34 logMAR, 1.23 ± 0.67 logMAR, p = 0,003). Whereas in follow up 6 months (1.23 ± 0.47 logMAR, 1.15 ± 0.68 logMAR, p = 0,242) and 12 months (0.94 ± 0.47 logMAR, 0.96 ± 0.44 logMAR, p = 0,840), there were no difference significant average of visual acuity.Conclusion: Visual acuity after following-up 3 and 6 months in age group of >2-17 years were better than age group of ≤2 years, whereas after following-up 12 months in age group ≤2 years, it was obtained that visual acuity was better than age group of >2-17 years.

scholarly journals The Comparison of Accelerated Corneal Crosslinking Treatment for Progressive Keratoconus in the Pediatric and Adult Age Groups: One-Year Results

2021 ◽  
Author(s):  
Mustafa Berhuni ◽  
Cem Ozturkmen
Keyword(s):  
Visual Acuity ◽  
Corneal Thickness ◽  
Age Groups ◽  
Age Group ◽  
Preoperative Period ◽  
Adult Group ◽  
Adult Age ◽  
Pediatric Age Group ◽  
Significant Difference ◽  
One Year

Abstract Purpose: To investigate the short-term results of accelerated crosslinking (A-CXL) treatment for progressive keratoconus in the pediatric and adult age groups. Materials and methods: The records of the 62 eyes of 40 patients who had undergone the A-CXL procedure (9 mV/cm2, 10 min) for progressive keratoconus between January 2015 and January 2019 were evaluated retrospectively. The patients were divided into 2 groups as the pediatric group (aged 17 years or less) and the adult group (aged 18 years or more) for statistical analysis. Pre- and post- 12th month A-CXL best-corrected visual acuity (BCVA), maximum keratometry (Kmax), sim K1, sim K2, corneal thickness at the thinnest point (thCT), and corneal astigmatism (CA) values of the patient groups were recorded. Results: The 29 eyes of 16 patients were included in the pediatric group and the 33 eyes of 24 patients were included in the adult group. The mean age was 13.50±3.05 years in the pediatric group and 23.58±4.37 years in the adult group. A significant improvement in BCVA and a significant decrease in thCT values were present in both groups 12 months after the surgery compared to the preoperative period. A decrease was present in the Kmax, sim K1, sim K2 and CA values in the pediatric group, but was not statistically significant. The decrease in Kmax, sim K1 and sim K2 values compared to the preoperative period was significant in the adult group, but the decrease in CA values was not significant. When the two groups were compared at the end of 12 months, only the sim K1 value was significantly lower in the adult group, and there was no significant difference between the other measurements. Conclusions: Better visual acuity improvement, a higher flattening rate, and less progression occur after 12 months with A-CXL treatment for progressive keratoconus in the adult age group compared to the pediatric age group.

First Clinical Experience with Anti-myelin Oligodendrocyte Glycoprotein Antibody-Positive Optic Neuritis

2020 ◽  
Vol 237 (04) ◽  
pp. 458-463 ◽  
Author(s):  
Jan Heckmann ◽  
Margarita Todorova ◽  
Stefanie Müller ◽  
Philip Julian Broser ◽  
Veit Sturm
Keyword(s):  
Visual Acuity ◽  
Optic Neuritis ◽  
Pulse Therapy ◽  
Myelin Oligodendrocyte Glycoprotein ◽  
Individual Treatment ◽  
Igg Antibodies ◽  
Intravenous Methylprednisolone ◽  
Finger Counting ◽  
The Right

Abstract Background Antibodies against myelin oligodendrocyte glycoprotein (MOG-IgG) have been consistently found in a range of demyelinating disorders. In this context, MOG-IgG-associated optic neuritis (ON) has been suggested as a new subset of optic neuropathy. However, clinical manifestations and distinctive characteristics have only rarely been described. Patients and Methods A retrospective case series of three patients with MOG-IgG-associated ON. Clinical morphological features using imaging techniques are presented. Results Three patients (8-year-old boy, 28-year-old female, 48-year-old male) were included. An 8-year-old boy suffered from a bilateral ON with severe visual loss. The best-corrected visual acuity (BCVA) was 0.05 in the right eye and finger counting in the left eye. The patient had a previous episode of acute disseminated encephalomyelitis (ADEM) with a right abducens nerve palsy. Visual acuity recovered after repeated cycles of intravenous methylprednisolone pulse therapy and 10 cycles of plasma exchange. During the last follow-up, BCVA was 0.9 in the right eye and 0.8 in the left eye. A 28-year-old female presented with a bilateral ON. Her BCVA was 0.5 in the right eye and 0.8 in the left eye. She fully recovered with pulse methylprednisolone therapy (1000 mg/d) with tapering after the second cycle and had a BCVA of 1.0 during the last follow-up visit. A 48-year-old male suffered from a relapsing bilateral ON. At first presentation, BCVA was 0.1 in the right eye and finger counting in the left eye. BCVA fully recovered after each pulse therapy with intravenous methylprednisolone (two cycles). Since the first relapse, the patient has been receiving long-term immunosuppression with rituximab. Despite rituximab and low-dose oral prednisone, the patient had another relapse with a left ON. After a third cycle with intravenous methylprednisolone, he partially recovered. BCVA at last follow-up was 1.0 in the right and 0.8 in the left eye. Conclusions MOG-IgG antibodies have been identified in different acquired demyelinating syndromes. The patients reported had an ADEM followed by bilateral ON, an isolated bilateral ON, and a relapsing bilateral ON. Individual treatment strategies led to substantial visual recovery in all patients. We recommend inclusion of MOG-IgG antibodies in the diagnostic workup at least after the first recurrence of ON since they can serve as a diagnostic and potential prognostic tool and might lead to specific therapeutic recommendations.

scholarly journals Changes in self-reported sleep duration with age - a 36-year longitudinal study of Finnish adults

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Christer Hublin ◽  
Lassi Haasio ◽  
Jaakko Kaprio
Keyword(s):  
Sleep Duration ◽  
Age Groups ◽  
Population Based ◽  
Age Group ◽  
Weibull Regression ◽  
Adult Age ◽  
Study Population ◽  
Sleep Length

Abstract Background Sleep deprivation is often claimed to be increasingly common, but most studies show small changes in sleep duration over the last decades. Our aim was to analyze long-term patterns in self-reported sleep duration in a population-based cohort. Methods Members of the Older Finnish Twin Cohort have responded to questionnaires in 1975 (N = 30,915 individuals, response rate 89%, mean age 36 years), 1981 (24,535, 84%, 41 years), 1990 (12,450, 77%, 44 years), and 2011 (8334, 72%, 60 years). Weibull regression models were used to model the effects of follow-up time and age simultaneously. Results Sleep duration has decreased in all adult age groups and in both genders. The mean duration was in men 7.57 h in 1975 and 7.39 in 2011, and in women 7.69 and 7.37, respectively. The decrease was about 0.5 min in men and 0.9 in women per year of follow-up. In the age-group 18–34 years, mean sleep length was 7.69 h in 1975 and 7.53 in 1990. Among 35–54-year-old it was 7.57 h in 1975 and 7.34 in 2011, and in the age group of 55+ year olds 7.52 and 7.38, correspondingly. The change was largest in middle-aged group: about 23 min or about 0.6 min per year of follow-up. Conclusions There has been a slight decrease in mean sleep duration during the 36-year follow-up. Although the sleep duration was longer in 1970s and 1980s, the probable main cause for the change in this study population is the effect of aging.

scholarly journals Vitreous Hemorrhage in Pediatric Age Group

2014 ◽  
Vol 2014 ◽  
pp. 1-12 ◽  
Author(s):  
Dora H. AlHarkan ◽  
Eman S. Kahtani ◽  
Priscilla W. Gikandi ◽  
Ahmed M. Abu El-Asrar
Keyword(s):  
Visual Acuity ◽  
Retinal Detachment ◽  
Vitreous Hemorrhage ◽  
Visual Outcome ◽  
Age Group ◽  
Pediatric Age ◽  
Pediatric Age Group ◽  
Good Visual Outcome ◽  
Negative Predictor

Purpose.To identify and study causes of vitreous hemorrhage (VH) in pediatric age group and to investigate factors predicting visual and anatomical outcomes.Procedure.A retrospective review of patients aged 16 years or less with the diagnosis of vitreous hemorrhage from January 2005 until December 2010.Results.A total number of 230 patients (240 eyes) were identified. Traumatic vitreous hemorrhage accounted for 82.5%. In cases of accidental trauma, final visual acuity of 20/200 was significantly associated with visual acuity of ≥20/200 at presentation and the absence of retinal detachment at last follow-up. Patients with nontraumatic vitreous hemorrhage were significantly younger with higher rates of enucleation/evisceration/exenteration and retinal detachment at last follow-up compared to traumatic cases.Conclusion.Trauma is the most common cause of VH in pediatric age group. In this group, initial visual acuity was the most important predictor for visual outcome, and the presence of retinal detachment is a negative predictor for final good visual outcome. The outcome is significantly worse in nontraumatic cases compared to traumatic cases.

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