Ketoacidosis associated with ketogenic diet in a non-diabetic lactating woman

2020 ◽  
Vol 13 (6) ◽  
pp. e234046
Author(s):  
Ali Alkhayat ◽  
Kevin Arao ◽  
Taro Minami ◽  
Kamran Manzoor
Keyword(s):  
Ketogenic Diet ◽  
Acid Level ◽  
Post Partum ◽  
Ringer Solution ◽  
Acute Onset ◽  
Hydroxybutyric Acid ◽  
Metabolic Derangement ◽  
Low Carbohydrate ◽  
Normal Glucose ◽  
Normal Glucose Level

A 37-year-old woman who had 8 weeks post partum, breast feeding and on a low carbohydrate and high protein (ketogenic) diet, was admitted to the hospital with acute onset of nausea, vomiting and abdominal pain of 1-day duration. On admission, she was found to have high anion gap metabolic acidosis, elevated beta-hydroxybutyric acid level, normal glucose level and evidence of ketoacidosis. She was treated with lactated Ringer solution, along with dextrose 5% solution with the resolution of symptoms and metabolic derangement.

scholarly journals Ketogenic Diet-Induced Diabetic Ketoacidosis in a Young Adult with Unrecognized Type 1 Diabetes

2021 ◽  
Vol 2021 ◽  
pp. 1-4
Author(s):  
Suranut Charoensri ◽  
Jin Sothornwit ◽  
Akeatit Trirattanapikul ◽  
Chatlert Pongchaiyakul
Keyword(s):  
Type 1 Diabetes ◽  
Diabetic Ketoacidosis ◽  
Ketogenic Diet ◽  
Weight Reduction ◽  
Rare Complication ◽  
Acute Onset ◽  
High Serum ◽  
Low Carbohydrate Diet ◽  
Low Carbohydrate

Ketogenic diet, a very low-carbohydrate diet and high-fat diet, has emerged as a popular approach for weight reduction, particularly in young adults. However, a serious but rare complication of the ketogenic diet is ketoacidosis associated with low carbohydrate intake, which should be cautiously monitored in people with a predisposition to the condition. We report a 22-year-old Thai woman with an unremarkable past medical history who presented with an acute onset of dyspnea of 2 days’ duration. Diabetic ketoacidosis was diagnosed by elevated capillary blood glucose, significant metabolic acidosis, and a high serum beta-hydroxybutyrate level. Low C-peptide level and positive islet autoantibodies confirmed the new diagnosis of type 1 diabetes in this patient. After her conditions were stabilized, the patient revealed that she began a ketogenic diet for weight reduction 4 days before her illness. Other precipitating factors were not identified. This highlights that ketogenic diet may increase diabetic ketoacidosis risk at the presentation of previously unrecognized type 1 diabetes.

scholarly journals A Low-Carbohydrate Ketogenic Diet and Treadmill Training Enhanced Fatty Acid Oxidation Capacity but Did Not Enhance Maximal Exercise Capacity in Mice

Nutrients ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 611
Author(s):  
Sihui Ma ◽  
Jiao Yang ◽  
Takaki Tominaga ◽  
Chunhong Liu ◽  
Katsuhiko Suzuki
Keyword(s):  
Fatty Acid ◽  
Fatty Acid Oxidation ◽  
Exercise Capacity ◽  
Ketogenic Diet ◽  
Maximal Exercise ◽  
Treadmill Running ◽  
Acid Oxidation ◽  
Oxidation Capacity ◽  
Low Carbohydrate ◽  
Maximal Exercise Capacity

The low-carbohydrate ketogenic diet (LCKD) is a dietary approach characterized by the intake of high amounts of fat, a balanced amount of protein, and low carbohydrates, which is insufficient for metabolic demands. Previous studies have shown that an LCKD alone may contribute to fatty acid oxidation capacity, along with endurance. In the present study, we combined a 10-week LCKD with an 8-week forced treadmill running program to determine whether training in conjunction with LCKD enhanced fatty acid oxidation capacity, as well as whether the maximal exercise capacity would be affected by an LCKD or training in a mice model. We found that the lipid pool and fatty acid oxidation capacity were both enhanced following the 10-week LCKD. Further, key fatty acid oxidation related genes were upregulated. In contrast, the 8-week training regimen had no effect on fatty acid and ketone body oxidation. Key genes involved in carbohydrate utilization were downregulated in the LCKD groups. However, the improved fatty acid oxidation capacity did not translate into an enhanced maximal exercise capacity. In summary, while favoring the fatty acid oxidation system, an LCKD, alone or combined with training, had no beneficial effects in our intensive exercise-evaluation model. Therefore, an LCKD may be promising to improve endurance in low- to moderate-intensity exercise, and may not be an optimal choice for those partaking in high-intensity exercise.

scholarly journals Effects of Two Months of Very Low Carbohydrate Ketogenic Diet on Body Composition, Muscle Strength, Muscle Area, and Blood Parameters in Competitive Natural Body Builders

Nutrients ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 374
Author(s):  
Antonio Paoli ◽  
Lorenzo Cenci ◽  
PierLuigi Pompei ◽  
Nese Sahin ◽  
Antonino Bianco ◽  
...  
Keyword(s):  
Body Composition ◽  
Muscle Strength ◽  
Ketogenic Diet ◽  
Inflammatory Cytokines ◽  
Blood Parameters ◽  
Maximal Strength ◽  
Muscle Area ◽  
Low Carbohydrate ◽  
Before And After ◽  
Adequate Quantity

Background: Ketogenic diet (KD) is a nutritional approach that restricts daily carbohydrates, replacing most of the reduced energy with fat, while maintaining an adequate quantity of protein. Despite the widespread use of KD in weight loss in athletes, there are still many concerns about its use in sports requiring muscle mass accrual. Thus, the present study sought to investigate the influence of a KD in competitive natural body builders. Methods: Nineteen volunteers (27.4 ± 10.5 years) were randomly assigned to ketogenic diet (KD) or to a western diet (WD). Body composition, muscle strength and basal metabolic rate were measured before and after two months of intervention. Standard blood biochemistry, testosterone, IGF-1, brain-derived neurotrophic factor (BDNF) and inflammatory cytokines (IL6, IL1β, TNFα) were also measured. Results: Body fat significantly decreased in KD (p = 0.030); whilst lean mass increased significantly only in WD (p < 0.001). Maximal strength increased similarly in both groups. KD showed a significant decrease of blood triglycerides (p < 0.001), glucose (p = 0.001), insulin (p < 0.001) and inflammatory cytokines compared to WD whilst BDNF increased in both groups with significant greater changes in KD (p < 0.001). Conclusions: KD may be used during body building preparation for health and leaning purposes but with the caution that hypertrophic muscle response could be blunted.

scholarly journals Middle and Long-Term Impact of a Very Low-Carbohydrate Ketogenic Diet on Cardiometabolic Factors: A Multi-Center, Cross-Sectional, Clinical Study

2015 ◽  
Vol 22 (4) ◽  
pp. 389-394 ◽  
Author(s):  
Arrigo F. G. Cicero ◽  
Maddalena Benelli ◽  
Marco Brancaleoni ◽  
Giuseppe Dainelli ◽  
Desiré Merlini ◽  
...  
Keyword(s):  
Clinical Study ◽  
Ketogenic Diet ◽  
Cross Sectional ◽  
Low Carbohydrate ◽  
Long Term Impact ◽  
Cardiometabolic Factors

Clinical Implications for Women of a Low-Carbohydrate or Ketogenic Diet With Intermittent Fasting

2021 ◽  
Vol 25 (2) ◽  
pp. 139-151
Author(s):  
Megan W. Arbour ◽  
Melissa Stec ◽  
Kelly C. Walker ◽  
Judith C. Wika
Keyword(s):  
Ketogenic Diet ◽  
Intermittent Fasting ◽  
Clinical Implications ◽  
Low Carbohydrate

scholarly journals Is there any Effect of Blood Glucose Level on Finger Biting?

2019 ◽  
Vol 2 (1) ◽  
Author(s):  
Hira Naeem Qureshi
Keyword(s):  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
High Glucose ◽  
Normal Glucose ◽  
Normal Glucose Level ◽  
Low Glucose ◽  
Glucose Meter ◽  
High Glucose Level

To interact glucose level of blood with finger biting was the goal of present research. 130 subjects took part in present research, where their glucose level of blood calculated. The normal glucose level in blood is in between 100 to 140mg/dl. The hyperglycemia is known as high glucose level while hypoglycemia is known as low glucose level. The biting of fingers in the mouth with teeth is known as finger biting. It also refer as onychophagia. There were 130 students take part in this research and they measured their sugar level by using glucose meter. Then they correlate the glucose level with finger biting. It was concluded from the present study that glucose level of blood has no impact on finger biting.

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