Peter's anomaly in an infant with a mild degree of Axenfeld's anomaly.

One of the basic components of intensive treatment of patients with an urgent abdominal pathology is perioperative infusion therapy. To analyze the perioperative dynamics of the water sectors of a body in the patients with a high surgical risk with acute abdominal pathology, a targeted regimen of infusion therapy was used to examine 35 patients. Perioperative targeted infusion therapy was carried out with balanced crystalloid solutions. With the non−invasive bioelectric rheography, the indices of water sectors of a body were studied. On the first day, the extracellular sector volume overflow was established due to an increase in interstitial volume. From the second day, the excess volumes of intravascular fluid and plasma were determined. On the third day there was a deficit of all the studied indices. On the fifth day of the post−surgery period, volumetric depletion of mild degree was noted. From the seventh to the tenth days, all the studied parameters to normal were reliably restored. A targeted regimen of infusion therapy in such patients was concluded to correct a moderate volume depletion on the tenth day after surgery by an excessive increase in plasma volume after six hours of treatment, the development of interstitial edema in the first two days, and the formation of mild volumetric depletion from third to seventh day. Key words: water sectors, goal−direct infusion therapy, depletion, urgent surgery, high surgical risk.

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A study on the proportion of hearing impairment among percussionists in Thrissur district of Kerala

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20210884 ◽

2021 ◽

Vol 9 (3) ◽

pp. 816

Author(s):

Jubina Bency A. T. ◽

Sarangi . ◽

Sebastian Roy ◽

Shalu Sara Mathew ◽

Shamseena A. ◽

...

Keyword(s):

Hearing Loss ◽

Hearing Impairment ◽

Work Experience ◽

Health Care Services ◽

Cross Sectional Study ◽

Moderate Degree ◽

Cross Sectional ◽

Hearing Ability ◽

Care Services ◽

Mild Degree

Background: Hearing loss is a cause of global concern. Percussionists are exposed to greater levels of continuous or intermittent noise than others. Little is known about the relationship between percussion activity and hearing impairment. The early detection of the same and subsequent management makes a significant reduction in the burden of health care services. The objective was to study the proportion of hearing impairment in percussionists in the district of Thrissur using an IOS based mobile application.Methods: A cross sectional study was done on percussionists from Thrissur district who has experience of more than five years and has no congenital or traumatic hearing loss. A predesigned semi structured questionnaire was given and hearing tests were done using a mobile application U hear in a sound proof setting to understand the current state of hearing ability amoung the percussionists.Results: A total of 39 subjects were involved in our study of which all were males. Mean age of our study population was 30.44+12.04. most of them were diagnosed with at least mild degree of hearing loss of one of the ear or both the ears. 15.4% of them had mild degree of hearing loss, 64.1% had moderate degree of hearing loss and 20.5% had severe hearing loss.Conclusions: The study shows percussionists are more exposed to sounds of various frequencies for longer duration, they are more prone to hearing loss. The study brought out that age is directly proportional to hearing loss, music induced hearing loss progress at a rate proportion to the work experience.

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Bilateral Peter's Anomaly in an Infant With 49,XXXXY Syndrome

Journal of Pediatric Ophthalmology & Strabismus ◽

10.3928/0191-3913-19980301-11 ◽

1998 ◽

Vol 35 (2) ◽

pp. 112-113

Author(s):

Kristin G Monaghan ◽

Patrick J Dennehy ◽

Daniel L VanDyke ◽

Lester Weiss

Keyword(s):

Peter’S Anomaly

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Acute Toxicity of the Recombinant and Native Phα1β Toxin: New Analgesic from Phoneutria nigriventer Spider Venom

Toxins ◽

10.3390/toxins10120531 ◽

2018 ◽

Vol 10 (12) ◽

pp. 531 ◽

Cited By ~ 2

Author(s):

Eliane Dallegrave ◽

Eliane Taschetto ◽

Mirna Bainy Leal ◽

Flavia Techera Antunes ◽

Marcus Gomez ◽

...

Keyword(s):

Clinical Signs ◽

Relative Weight ◽

Serum Biochemistry ◽

Renal Tissue ◽

Organ Weight ◽

Female Rats ◽

Mild Degree ◽

Physiological Limits ◽

Voltage Dependent ◽

Phoneutria Nigriventer

Phα1β, a purified peptide from the venom of the spider Phoneutria nigriventer, and its recombinant form CTK 01512-2 are voltage-dependent calcium channel (CaV) blockers of types N, R, P/Q, and L with a preference for type N. These peptides show analgesic action in different pain models in rats. The aim of this study was to evaluate the acute intrathecal toxicity of the native and recombinant Phα1β toxin in Wistar rats. Clinical signs, serum biochemistry, organ weight, and histopathological alterations were evaluated in male and/or female rats. Dyspnea was observed in males, hyporesponsiveness in females, and Straub tail and tremors in both genders. There were no significant differences in male organ weight, although significant differences in the female relative weight of the adrenal glands and spleen have been observed; these values are within the normal range. Serum biochemical data revealed a significant reduction within the physiological limits of species related to urea, ALT, AST, and FA. Hepatic and renal congestion were observed for toxin groups. In renal tissue, glomerular infiltrates were observed with increased glomerular space. These histological alterations were presented in focal areas and in mild degree. Therefore, Phα1β and CTK 01512-2 presented a good safety profile with transient toxicity clinical signals in doses higher than used to obtain the analgesic effect.

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Pulmonary function in men after oxygen breathing at 3.0 ATA for 3.5 h

Journal of Applied Physiology ◽

10.1152/jappl.1991.71.3.878 ◽

1991 ◽

Vol 71 (3) ◽

pp. 878-885 ◽

Cited By ~ 24

Author(s):

J. M. Clark ◽

R. M. Jackson ◽

C. J. Lambertsen ◽

R. Gelfand ◽

W. D. Hiller ◽

...

Keyword(s):

Pulmonary Function ◽

Forced Vital Capacity ◽

Vital Capacity ◽

Large Change ◽

Forced Expiratory Volume ◽

Diffusing Capacity ◽

Mild Degree ◽

Oxygen Breathing ◽

Multiple Organs ◽

Expiratory Flow

As a pulmonary component of Predictive Studies V, designed to determine O2 tolerance of multiple organs and systems in humans at 3.0–1.5 ATA, pulmonary function was evaluated at 1.0 ATA in 13 healthy men before and after O2 exposure at 3.0 ATA for 3.5 h. Measurements included flow-volume loops, spirometry, and airway resistance (Raw) (n = 12); CO diffusing capacity (n = 11); closing volumes (n = 6); and air vs. HeO2 forced vital capacity maneuvers (n = 5). Chest discomfort, cough, and dyspnea were experienced during exposure in mild degree by most subjects. Mean forced expiratory volume in 1 s (FEV1) and forced expiratory flow at 25–75% of vital capacity (FEF25–75) were significantly reduced postexposure by 5.9 and 11.8%, respectively, whereas forced vital capacity was not significantly changed. The average difference in maximum midexpiratory flow rates at 50% vital capacity on air and HeO2 was significantly reduced postexposure by 18%. Raw and CO diffusing capacity were not changed postexposure. The relatively large change in FEF25–75 compared with FEV1, the reduction in density dependence of flow, and the normal Raw postexposure are all consistent with flow limitation in peripheral airways as a major cause of the observed reduction in expiratory flow. Postexposure pulmonary function changes in one subject who convulsed at 3.0 h of exposure are compared with corresponding average changes in 12 subjects who did not convulse.

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Type II Peter’s anomaly with histopathological proof: a case report

BMC Ophthalmology ◽

10.1186/s12886-017-0502-7 ◽

2017 ◽

Vol 17 (1) ◽

Author(s):

Rui-Qi Chang ◽

Yu Du ◽

Xiang-Jia Zhu ◽

Yi Lu

Keyword(s):

Case Report ◽

Type Ii ◽

Peter’S Anomaly

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Anthelmintic Efficacy of Strongyle Nematodes to Ivermectin and Fenbendazole on Working Donkeys (Equus asinus) in and around Hosaena Town, Southern Ethiopia

Veterinary Medicine International ◽

10.1155/2020/4868797 ◽

2020 ◽

Vol 2020 ◽

pp. 1-7

Author(s):

Haben Fesseha ◽

Mesfin Mathewos ◽

Friat Kidanemariam

Keyword(s):

Anthelmintic Resistance ◽

Influencing Factor ◽

Southern Ethiopia ◽

Control Programs ◽

Mild Degree ◽

Anthelmintic Efficacy ◽

Equus Asinus ◽

The Mean ◽

Severe Degree ◽

And Control

Background. Gastrointestinal helminth parasite infection is a major influencing factor against profitability of working equines all over the world. Objectives. A study was conducted from October 2016 to May 2017 in and around Hosaena to determine the efficacy of benzimidazole (BZ) and avermectin (AVM) chemical groups against strongyle nematodes in working donkeys. Methods. A total of 230 donkeys from Hosaena, Soro, Anlemo, and Gombora were randomly allocated into 5 groups of 46 donkeys in each group. All groups, except group 1 (control), were treated with ivermectin 1%, ivertong 10%, fenbendazole, and Fenacure 750 mg, respectively. Fecal samples were collected perrectally before treatment (day 0) and after treatment (day 14), and an egg per gram (EPG) value of >200 was used as a cutoff for inclusion to assess the efficacy of anthelmintics. Results. Accordingly, the study revealed that AVM was effective against strongyle nematodes of donkeys with the mean fecal egg count reduction (FECR) of 100% in three study areas and 97.2% in one study area, respectively, whereas BZ resistance was suspected in the areas where the drug was tested, with the mean FECR of less than 94% in the three study areas. The study also revealed that 73% of the donkeys were affected with a severe degree of strongyle infection as determined by EPG, while 10.4% of donkeys were affected with a mild degree of Parascaris equorum infection. Conclusions. The findings of the present study are expected to serve as baseline data for future investigations and control actions to design realistic control programs to minimize factors that favor emergence of anthelmintic resistance and improve the overall health of the donkeys. Thus, further detailed studies are needed to determine the factors that reduce anthelmintic efficacy and increase anthelmintic resistance in donkeys.

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PETER’S ANOMALY

JURNAL BIOMEDIK (JBM) ◽

10.35790/jbm.3.1.2011.860 ◽

2013 ◽

Vol 3 (1) ◽

Author(s):

Laya Rares

Keyword(s):

Penetrating Keratoplasty ◽

Corneal Opacity ◽

Health Condition ◽

Pressure Management ◽

Filtration Surgery ◽

Intra Ocular Pressure ◽

Ocular Pressure ◽

One Year ◽

The Right ◽

Peter’S Anomaly

Abstract: Peter’s anomaly is a congenital corneal anomaly characterized by central or paracentral opacity. Around 60-80% of this anomaly is bilateral. We reported a girl of one year and six months as having bilateral corneal opacity since she was born. Diagnosis was based on ophthalmological examinations: the vision of the right and left eyes was ‘fix and follow the light’; sensoric nystagmus of both eyes; intra-ocular pressure of the right eye 37 mm Hg and of the left eye 40 mm Hg; corneal diameters of both eyes were 11 mm; 5-mm-central opacity of both cornea; both eye movements to all directions were normal; anterior chambers were shallow; iris was attached to the corneal endothelium; both lenses were difficult to be evaluated due to corneal opacity; fundal reflexes in both eyes were negative. The early medication given was thymolol 0.5% to decrease the intra-ocular pressure. If her health condition improved, a penetrating keratoplasty and a filtration surgery were recommended under general anaesthesia. Key words: Peter’s anomaly, corneal opacity, intraocular pressure, management. Abstrak: Peter’s anomaly merupakan kelainan kongenital kornea yang ditandai dengan kekeruhan pada kornea bagian sentral ataupun parasentral. Sekitar 60-80% kasus Peter’s anomaly terjadi bilateral. Kami melaporkan kasus Peter’s Anomaly pada seorang anak berusia satu tahun enam bulan dengan kekeruhan pada kedua mata sejak lahir. Diagnosis ditegakkan berdasarkan pemeriksaan oftalmologis dimana didapatkan visus okuli dekstra dan sinistra fix and follow the light, nistagmus sensoris pada kedua mata, tekanan intra okuler pada mata kanan 37 mm Hg dan pada mata kiri 40 mmHg. Diameter kornea kedua mata 11 mm, adanya kekeruhan pada sentral kornea (stroma) dengan diameter 5 mm pada kedua mata. Pergerakan kedua mata ke semua arah normal. Bilik mata anterior dangkal, iris melekat pada endotel kornea, lensa kedua mata sukar dievaluasi oleh karena kekeruhan pada kornea. Refleks fundus negatif pada kedua mata. Penanganan awal yang diberikan berupa medikamentosa (timolol 0,5%) untuk menurunkan tekanan intra okuler sambil menunggu keadaan umum membaik untuk dilakukan penetrating keratoplasty and filtration surgery dibawah anastesi umum. Kata Kunci: Peter’s anomaly, kekeruhan kornea, tekanan intra okuler, penanganan.

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Persistent inflammation, immunosuppression and catabolism syndrome: mechanisms of sarcopenia and ways of correction

EMERGENCY MEDICINE ◽

10.22141/2224-0586.16.7-8.2020.223712 ◽

2021 ◽

Vol 16 (7-8) ◽

pp. 110-117

Author(s):

S.M. Chuklin ◽

S.S. Chuklin ◽

G.V. Shershen

Keyword(s):

Intensive Care ◽

Critical Illness ◽

Necrotizing Pancreatitis ◽

Clinical Manifestations ◽

Severe Trauma ◽

Significant Loss ◽

Mild Degree ◽

Persistent Inflammation ◽

Chronic Critical Illness ◽

Severe Pathology

Due to advances in intensive care, many patients with severe pathology are discharged from intensive care units. However, prolonged mild degree inflammation persists in some patients, recovery is protracted, and chronic critical illness develops in them. In addition, persistent inflammation, immunosuppression and catabolism arise. In 2012, this condition was identified as a separate syndrome, which can be observed after severe trauma and burns, sepsis, necrotizing pancreatitis. Significant loss of muscle mass that is difficult to correct is one of the leading clinical manifestations in this case. Using literature from the MEDLINE database, modern ideas about the mechanisms of sarcopenia in the persistent inflammation, immunosuppression and catabolism syndrome and possible ways of optimal anabolic support are described.

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