scholarly journals Trends in known and undiagnosed diabetes, HbA1c levels, cardiometabolic risk factors and diabetes treatment target achievement in repeated cross-sectional surveys: the population-based Tromsø Study 1994–2016

BMJ Open ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. e041846
Author(s):  
Petja Lyn Langholz ◽  
Tom Wilsgaard ◽  
Inger Njølstad ◽  
Rolf Jorde ◽  
Laila Arnesdatter Hopstock
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Cardiometabolic Risk ◽  
Population Based ◽  
Cardiometabolic Risk Factors ◽  
Undiagnosed Diabetes ◽  
Cross Sectional ◽  
Treatment Target ◽  
The Metabolic Syndrome ◽  
Hba1c Levels

ObjectivesThe aim of this study was to investigate time trends in known and undiagnosed diabetes, glycated haemoglobin (HbA1c) levels and other cardiometabolic risk factors in the general population as well as treatment target achievement among those with diabetes.Design and settingRepeated cross-sectional surveys in the population-based Tromsø Study.MethodsWe used age-adjusted generalised estimating equation models to study trends in self-reported and undiagnosed (HbA1c ≥6.5%) diabetes, cardiometabolic risk factors and the metabolic syndrome in 27 281 women and men aged 40–84 years examined in up to four surveys of the Tromsø Study between 1994 and 2016. Further, we analysed trends in diabetes treatment target achievement.ResultsDuring 1994–2016, diabetes prevalence increased in women (2.3% to 4.6%) and men (2.4% to 5.8%) and in all age groups, while the proportion of undiagnosed diabetes in women (32% to 17%) and men (37% to 24%) decreased. Blood pressure and total cholesterol decreased, while waist circumference increased in participants with and without diabetes, leading to a relatively stable prevalence of the metabolic syndrome throughout the study period. There was a marginal increase in HbA1c levels among participants without diabetes. Only half of those with diabetes achieved the treatment target of HbA1c ≤7.0%.ConclusionIn the last two decades, diabetes prevalence increased, while the proportion of undiagnosed diabetes declined. The prevalence of the metabolic syndrome remained stable throughout, driven by opposing trends with an increase in obesity and a decrease in other cardiometabolic risk factors. HbA1c treatment target achievement did not improve.

scholarly journals Trends in known and undiagnosed diabetes, HbA1c levels, cardio-metabolic risk factors and diabetes treatment target achievement in repeated cross-sectional surveys – The Tromsø Study 1994-2016

2020 ◽  
Author(s):  
Petja Lyn Langholz ◽  
Tom Wilsgaard ◽  
Inger Njølstad ◽  
Rolf Jorde ◽  
Laila Arnesdatter Hopstock
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Metabolic Risk Factors ◽  
Undiagnosed Diabetes ◽  
Metabolic Risk ◽  
Diabetes Treatment ◽  
Cross Sectional ◽  
Treatment Target ◽  
The Metabolic Syndrome ◽  
Hba1c Levels

AbstractObjectivesThe aim of this study was to investigate time trends in known and undiagnosed diabetes, HbA1c levels, and other cardio-metabolic risk factors in the general population as well as treatment target achievement among those with diabetes.Design and settingRepeated cross-sectional surveys in the population-based Tromsø Study.MethodsWe used age-adjusted generalized estimating equation models to study trends in self-reported and undiagnosed (HbA1c ≥6.5%) diabetes, cardio-metabolic risk factors and the metabolic syndrome in 27281 women and men aged 40-84 years examined in up to four surveys of the Tromsø Study between 1994 and 2016. Further, we analyzed trends in diabetes treatment target achievement.ResultsDuring 1994-2016 diabetes prevalence increased in women (2.3% to 3.9%) and men (2.4% to 5.3%) and in all age-groups, while the proportion of undiagnosed diabetes in women (33% to 20%) and men (37% to 27%) decreased. Blood pressure and total cholesterol decreased, while waist circumference increased in participants with and without diabetes, leading to a relatively stable prevalence of the metabolic syndrome throughout the study period. There was a marginal increase in HbA1c levels among participants without diabetes. Only half of those with diabetes achieved the treatment target of HbA1c ≤7.0%.ConclusionIn the last two decades diabetes prevalence increased, while the proportion of undiagnosed diabetes declined. The prevalence of the metabolic syndrome remained stable throughout, driven by opposing trends with an increase in obesity and a decrease in other cardio-metabolic risk factors. HbA1c treatment target achievement did not improve.

scholarly journals Association of intraocular pressure with the metabolic syndrome and novel cardiometabolic risk factors

Eye ◽  
2009 ◽  
Vol 24 (6) ◽  
pp. 1037-1043 ◽  
Author(s):  
Y C Chang ◽  
J-W Lin ◽  
L C Wang ◽  
H M Chen ◽  
J J Hwang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Intraocular Pressure ◽  
Cardiometabolic Risk ◽  
Cardiometabolic Risk Factors ◽  
The Metabolic Syndrome

scholarly journals Optimal waist:height ratio cut-off point for cardiometabolic risk factors in Turkish adults

2009 ◽  
Vol 13 (4) ◽  
pp. 488-495 ◽  
Author(s):  
Ahmet Selçuk Can ◽  
Emine Akal Yıldız ◽  
Gülhan Samur ◽  
Neslişah Rakıcıoğlu ◽  
Gülden Pekcan ◽  
...  
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Risk Factor ◽  
Cardiometabolic Risk ◽  
Roc Curves ◽  
Cross Sectional Study ◽  
Cardiometabolic Risk Factors ◽  
Youden Index ◽  
Cross Sectional ◽  
Men And Women

AbstractObjectiveTo identify the optimal waist:height ratio (WHtR) cut-off point that discriminates cardiometabolic risk factors in Turkish adults.DesignCross-sectional study. Hypertension, dyslipidaemia, diabetes, metabolic syndrome score ≥2 (presence of two or more metabolic syndrome components except for waist circumference) and at least one risk factor (diabetes, hypertension or dyslipidaemia) were categorical outcome variables. Receiver-operating characteristic (ROC) curves were prepared by plotting 1 − specificity on the x-axis and sensitivity on the y-axis. The WHtR value that had the highest Youden index was selected as the optimal cut-off point for each cardiometabolic risk factor (Youden index = sensitivity + specificity − 1).SettingTurkey, 2003.SubjectsAdults (1121 women and 571 men) aged 18 years and over were examined.ResultsAnalysis of ROC coordinate tables showed that the optimal cut-off value ranged between 0·55 and 0·60 and was almost equal between men and women. The sensitivities of the identified cut-offs were between 0·63 and 0·81, the specificities were between 0·42 and 0·71 and the accuracies were between 0·65 and 0·73, for men and women. The cut-off point of 0·59 was the most frequently identified value for discrimination of the studied cardiometabolic risk factors. Subjects classified as having WHtR ≥ 0·59 had significantly higher age and sociodemographic multivariable-adjusted odds ratios for cardiometabolic risk factors than subjects with WHtR < 0·59, except for diabetes in men.ConclusionsWe show that the optimal WHtR cut-off point to discriminate cardiometabolic risk factors is 0·59 in Turkish adults.

scholarly journals Prevalence and determinants of the metabolic syndrome among Tunisian adults: results of the Transition and Health Impact in North Africa (TAHINA) project

2012 ◽  
Vol 16 (4) ◽  
pp. 582-590 ◽  
Author(s):  
Hanen Belfki ◽  
Samir Ben Ali ◽  
Hajer Aounallah-Skhiri ◽  
Pierre Traissac ◽  
Souha Bougatef ◽  
...  
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
North Africa ◽  
Health Impact ◽  
Population Based ◽  
Cross Sectional Study ◽  
Intervention Programme ◽  
Cvd Risk ◽  
Cross Sectional ◽  
The Metabolic Syndrome

AbstractObjectiveTo determine the prevalence of metabolic syndrome (MetS) and its components and to evaluate the relationship between this diagnosis and cardiovascular risk factors, demographic and socio-economic variables.DesignA cross-sectional study using a questionnaire including information on sociodemographic and CVD risk factors. Blood pressure, anthropometric indices, fasting glucose and lipid profile were measured. MetS was defined according to the criteria of the National Cholesterol Education Program, Adult Treatment Panel III.SettingThe whole Tunisian territory; Transition and Health Impact in North Africa (TAHINA) project.SubjectsA total of 4654 individuals (1840 men and 2814 women), aged 35 to 74 years, who participated in the Tunisian national survey.ResultsThe overall prevalence of MetS was 30·0 %, higher in women (36·1 %) than in men (20·6 %; P < 0·001). In both genders MetS prevalence increased significantly with age (P < 0·001), but this increase was more important in women. Multiple regression analyses showed that the odds for MetS increased significantly with urban area for both men and women (P < 0·05 and P < 0·001, respectively). The multivariate models showed also that the odds for MetS increased significantly with increasing level of education and in those with a family history of CVD for men (both P < 0·05) and after the menopausal transition for women (P < 0·05).ConclusionsThe study highlights the MetS problem in a middle-income developing country. There is an urgent need for a comprehensive, integrated, population-based intervention programme to ameliorate the growing problem of MetS in Tunisians.

scholarly journals A population-based cross-sectional study of the association between facial morphology and cardiometabolic risk factors in adolescence

BMJ Open ◽  
2013 ◽  
Vol 3 (5) ◽  
pp. e002910 ◽  
Author(s):  
Jelena Djordjevic ◽  
Debbie A Lawlor ◽  
Alexei I Zhurov ◽  
Arshed M Toma ◽  
Rebecca Playle ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiometabolic Risk ◽  
Population Based ◽  
Cross Sectional Study ◽  
Cardiometabolic Risk Factors ◽  
Facial Morphology ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Irregularity of energy intake at meals: prospective associations with the metabolic syndrome in adults of the 1946 British birth cohort

2015 ◽  
Vol 115 (2) ◽  
pp. 315-323 ◽  
Author(s):  
Gerda K. Pot ◽  
Rebecca Hardy ◽  
Alison M. Stephen
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Waist Circumference ◽  
Energy Intake ◽  
Cardiometabolic Risk ◽  
Cardiometabolic Risk Factors ◽  
Logistic Regression Models ◽  
The Metabolic Syndrome ◽  
Increased Risk ◽  
Health And Development

AbstractIrregularity in eating patterns could be a potential cardiometabolic risk factor. We aimed to study the associations of irregular intake of energy at meals in relation to cardiometabolic risk factors 10 and 17 years later. Variability of energy intake data – derived from 5-d estimated diet diaries of cohort members of the National Survey for Health and Development collected at ages 36 (n1416), 43 (n1505) and 53 years (n1381) – was used as a measure for irregularity. Associations between meal irregularity scores with cardiometabolic risk factors measured 10 and 17 years later were investigated using linear mixed models and logistic regression models. The results showed that irregularity scores changed significantly over the years (P<0·05). At age 36 years, subjects with a more irregular intake of energy at lunch (OR 1·42; 95 % CI 1·05, 1·91) and between meals (OR 1·35; 95 % CI 1·01, 1·82) had an increased risk for the metabolic syndrome 17 years later; at lunch was also associated with an increased waist circumference (OR 1·58; 95 % 1·27, 1·96) and TAG levels (OR 1·33; 95 % CI 1·02, 1·72). At age 43 years, subjects with a more irregular intake at breakfast had an increased risk of the metabolic syndrome 10 years later (OR 1·53; 95 % CI 1·15, 2·04), as well as an increased BMI (OR 1·66; 95 % CI 1·31, 2·10), waist circumference (OR 1·53; 95 % CI 1·23, 1·90) and diastolic blood pressure (OR 1·42; 95 % CI 1·13, 1·78). In conclusion, subjects with a more irregular intake of energy, mostly at breakfast and lunch, appeared to have an increased cardiometabolic risk 10 and 17 years later.

scholarly journals Metabolic Syndrome Knowledge among Adults with Cardiometabolic Risk Factors: A Cross-Sectional Study

2019 ◽  
Vol 16 (1) ◽  
pp. 159 ◽  
Author(s):  
Qun Wang ◽  
Sek Ying Chair ◽  
Eliza Mi-Ling Wong ◽  
Ruth E. Taylor-Piliae ◽  
Xi Chen Hui Qiu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Formal Education ◽  
Cardiometabolic Risk ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Cardiometabolic Risk Factors ◽  
Cross Sectional ◽  
Lipid Management ◽  
History Of

Metabolic syndrome (MetS) is a cluster of cardiometabolic risk factors. Many people may be unaware of their risk for MetS. A cross-sectional, descriptive study was conducted among hospitalized patients with at least one cardiometabolic risk factor in Mainland China. This study assessed the MetS knowledgelevel(through MetS Knowledge Scale, MSKS) and examined the potential predictors by regression analysis. A total of 204 patients aged 58.5 ± 10.1 years (55% males) participated in this study. The majority of participants had no history of hypertension (54%), dyslipidemia (79%), or diabetes (85%). However, 56% of these participants had at least three cardiometabolic risk factors, indicating the presence of MetS. The average MSKS was very low (mean = 36.7±18.8, possible range = 0–100), indicating the urgent needs of MetS education in current practice. Predictors of better MetS knowledge included higher educational level, history of dyslipidemia, and normal high-density lipoprotein cholesterol (F (8, 195) = 9.39, adjusted R2 = 0.192, p< 0.001). In conclusion, adults with cardiometabolic risk factors are at risk of developing MetS, but with a low level of knowledge. Specific health education on MetS should be provided, particularly for those with limited formal education or inadequate lipid management.

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