scholarly journals Amlodipine – not a significant contributor to clopidogrel non-response?

Heart ◽  
2013 ◽  
Vol 99 (7) ◽  
pp. 437-439 ◽  
Author(s):  
Rolf P Kreutz ◽  
David A Flockhart
Author(s):  
Debolina Dutta ◽  
Prem Mirchandani ◽  
K. P. Anasha

The Indian IT/ITeS industry is a significant contributor to India’s GDP and has had an impressive growth trajectory. However, it continues to be plagued with talent shortages, managing employee satisfaction, growth aspirations and reducing attrition. COVID-19 has presented an unprecedented opportunity for IT service organisations to transform the established paradigm of working. The industry has been exploring non-linear growth models that address the talent demand-supply gap. With skilled talent shortage continuing to limit the industry growth, non-linear initiatives of growth are urgently required. We propose a model of ‘Internal Gig’ worker (I-GIG) for the IT services industry. The new I-GIG workforce would be providing non-linear outcomes without increasing costs significantly. We also argue that this model would be motivational for employees who opt for it, with commensurate reward motivations to engage them. Additionally, this model would enable the workanywhere, anytime and leverage talent availability on a global scale.


2007 ◽  
Vol 10 (5) ◽  
pp. 703-711 ◽  
Author(s):  
Ellen L. Goode ◽  
Stacey S. Cherny ◽  
Joe C. Christian ◽  
Gail P. Jarvik ◽  
Mariza de Andrade

AbstractBody-mass index (BMI), total cholesterol (TC), lowdensity lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and triglyceride (TG) levels are known to be highly heritable. We evaluated the genetic and environmental relationships of these measures over time in an analysis of twin pairs. Monozygotic (235 pairs) and dizygotic (260 pairs) male twins were participants in the National Heart Lung and Blood Institute Veteran Twin Study, and were followed with three clinical exams from mean age 48 years to mean age 63 years. Structural equation modeling (SEM) with adjustment forAPOEgenotype (a significant contributor to TC and LDL-C) was used to assess longitudinal patterns of heritability. Results indicated a contribution of genetic factors to BMI, TC, LDL-C, HLD-C, and TG. Modest increases over time were observed in the heritability of BMI (from 0.48 to 0.61), TC (from 0.46 to 0.57), LDL-C (from 0.49 to 0.64), and HDL-C (from 0.50 to 0.62), but this trend was not present for TG. There was a corresponding decrease in shared environmental influences over time for these traits, although shared environment was a significant contributor only for HDL-C. Moreover, we observed that genetic influences for all measures were significantly correlated over time, and we found no evidence of age-specific genetic effects. In summary, longitudinal analyses of twin data indicate that genetic factors do not account for a significant proportion of the variation in age-related changes of BMI or lipid and lipoprotein levels.


2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Dr Nalini Malhotra

The present paper seeks to investigate the Machiavellianism in relation with Emotional Intelligence among Adolescents. It was hypothesized that Machiavellianism and Emotional Intelligence would be negatively correlated and Emotional Intelligence would be a significant contributor in predicting variance in Machiavellianism. In order to test the hypothesis 240 adolescents (120 females and 120 males) in the age range of 13 to 18 years were selected through random sampling. The measures used were Machiavellianism Scale (Mach IV Scale) and Modified Schutte Emotional Intelligence Scale (Schutte 1998). The correlation coefficient and regression analysis were used to assess the data. The results revealed significant and negative relationship between Machiavellianism and Emotional Intelligence .Emotional Intelligence emerged as a significant predictor of Machiavellianism. Thus, considering the possibility that individuals might have a dispositional tendency to emotionally manipulative behaviour immediately brings to mind the trait of Machiavellianism.


Author(s):  
Sam McLeod

Feasibility consists of inter-related questions. Often, organizations place a narrow technical focus on the technical feasibility of a preferred option (Lucae et al. 2014; Samset 2009). Hence, many frameworks, including TELOS, have been developed to encourage more holistic feasibility appraisal (Bause et al. 2014; Burch 1992). Poorly considered feasibility studies are a significant contributor to project failure, loss of reputation, lost opportunity, excess sunk costs, loss of morale, and litigation (see Sahu 2014).


Author(s):  
Suja R. Nair

Since the past two decades the concept of women entrepreneurship has gained recognition as a significant contributor towards the economic growth of the country. This can be attributed to the many encouraging factors like family support, flexibility in work family schedule, encouraging policies etc. Nevertheless, there also exist certain barriers that hinder their path of progress. In the context of globalization today, women entrepreneurs across nations are also engaged in identifying opportunities for further growth. In this pursuit they face a number of challenges amidst the opportunities. The chapter intends to make a contribution to the topic of women entrepreneurship by examining what initiates entrepreneurship among individuals, comparison between male and female entrepreneurs, factors that encourage women entrepreneurs as well as those that inhibit their growth and on ways to overcome the challenges they face.


2020 ◽  
Vol 6 (2) ◽  
pp. 87-105
Author(s):  
Arkadiusz Rojczyk ◽  
Andrzej Porzuczek

This paper addresses the issue of speech rhythm as a cue to non-native pronunciation. In natural recordings, it is impossible to disentangle rhythm from segmental, subphonemic or suprasegmental features that may influence nativeness ratings. However, two methods of speech manipulation, that is, backwards content-masked speech and vocoded speech, allow the identification of native and non-native speech in which segmental properties are masked and become inaccessible to the listeners. In the current study, we use these two methods to compare the perception of content-masked native English speech and Polish-accented speech. Both native English and Polish-accented recordings were manipulated using backwards masked speech and 4-band white-noise vocoded speech. Fourteen listeners classified the stimuli as produced by native or Polish speakers of English. Polish and English differ in their temporal organization, so, if rhythm is a significant contributor to the status of non-native accentedness, we expected an above-chance rate of recognition of native and non-native English speech. Moreover, backwards content-masked speech was predicted to yield better results than vocoded speech, because it retains some of the indexical properties of speakers. The resultsshow that listeners are unable to detect non-native accent in Polish learners of English from backwards and vocoded speech samples.


2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Liang Song ◽  
Hua-Zheng Lu ◽  
Xing-Liang Xu ◽  
Su Li ◽  
Xian-Meng Shi ◽  
...  

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