scholarly journals 219 Work related stress and increased risk of low birth weight, pregnancy-induced hypertension and preeclampsia

2013 ◽  
Vol 70 (Suppl 1) ◽  
pp. A74.2-A74
Author(s):  
T Brand ◽  
Milder
PEDIATRICS ◽  
1992 ◽  
Vol 90 (3) ◽  
pp. 430-435
Author(s):  
Ana Mouzinho ◽  
Charles R. Rosenfeld ◽  
Pablo J. Sanchez ◽  
Rick Risser

Neonatal neutropenia occurs in ∼50% of newborns delivered by women with pregnancy-induced hypertension. It is thought to be transient, independent of birth weight and gestational age, and unassociated with significant risks, including infection. It recently was suggested that neonatal neutropenia occurs primarily in smaller, younger neonates, is related to the severity of pregnancy-induced hypertension, and importantly, may be associated with an increased risk for nosocomial infection. We examined these points in a large inborn population in consecutive years, performing retrospective (n = 110, 1989) and prospective (n = 151, 1990) studies in low birth weight (≤2200 g) neonates delivered by women with pregnancy-induced hypertension. Overall, 40% to 50% of neonates studied developed neonatal neutropenia, and they were younger and smaller (P < .01) than non-neutropenic neonates. In the prospective study, neutropenic neonates were more likely to have mothers with severe pregnancy-induced hypertension (P < .001), and the incidence of neonatal neutropenia was primarily among neonates <30 weeks of gestation and <1500 g birth weight, ∼80% vs 35% to 45% in older, larger neonates or infants (P < .001). Although nosocomial infection occurred more frequently among the group of neutropenic neonates in the prospective study (P < .02), the incidence was similar to that in matched non-neutropenic controls delivered of normotensive women. Thrombocytopenia (<100 000/mm3) was not more frequent in neutropenic neonates. Although neonatal neutropenia occurs in 40% to 50% of low birth weight neonates from pregnancies complicated by pregnancy-induced hypertension, this primarily reflects an incidence of 80% among neonates <30 weeks gestation. There is no apparent increased risk for development of nosocomial infection or thrombocytopenia.


2019 ◽  
Vol 180 (4) ◽  
pp. 257-263
Author(s):  
Guy Fagherazzi ◽  
Gaelle Gusto ◽  
Douae El Fatouhi ◽  
Francesca Romana Mancini ◽  
Beverley Balkau ◽  
...  

Hypothesis Previous work suggested no or inconsistent associations between components of work-related stress and type 2 diabetes risk, but suggested sex-specific differences should be further investigated, as women potentially had higher risks. Methods We analyzed data from 73 517 women, mostly teachers, from the E3N cohort study followed for 22 years (1992–2014), to study the association between mentally tiring work, used as a proxy of job demands, and type 2 diabetes risk. Univariate and multivariable Cox regression models were used to estimate hazard ratios and 95% confidence intervals. Results A total of 4187 incident cases of type 2 diabetes cases were observed. There was a higher type 2 diabetes risk for women with a ‘Very mentally tiring work’ when compared to women with ‘Little or not mentally tiring work’ (HR = 1.21 (1.09–1.35)). This association was independent of unhealthy lifestyle and traditional metabolic factors. An interaction between mentally tiring work and BMI was detected (P < 0.0001), with a stronger association being observed in non-overweight women, HR = 1.26 (1.08–1.47) vs HR = 1.14 (0.98, 1.32), in overweight women. Conclusions We observed an increased risk of type 2 diabetes associated with mentally tiring work, used as a proxy of job demands. These observational results suggest the importance of taking into consideration the potential long-term metabolic impact of work-related stress for women working in a demanding environment. Increased support for such women should be investigated in intervention studies.


2020 ◽  
Vol 14 (1) ◽  
pp. 1-6
Author(s):  
Vinodkumar Mugada ◽  
Raj Kiran Kolakota ◽  
Abhilasha Sakalabathula ◽  
Bindu Pavani Kola

Background: Low birth weight is an alarming problem in developing countries and has severe future complications. Aim of the study: Our study aimed to compare the risk factors among mothers with low and normal birth weight babies. Materials and Methods: A cross-sectional study was carried out on 1000 mothers with normal and low birth weight babies (500 per group) over two years. Maternal parameters including age, hemoglobin levels, gravida, maternal weight gain, height, pregnancy-induced hypertension, etc., were collected along with anthropometric data of the child. We compared risk factors among the low and normal birth weight babies using the chi-square test, determining statistical significance at p<0.05, and high statistical significance at p<0.01. Results: Highly statistically significant associations were observed between low birth weight and seven variables: maternal age (p=0.0074), maternal height (p<0.0001), weight (p<0.0001), weight gain (p<0.0001), hemoglobin (p<0.0001), severe anemia (p<0.0001), and pregnancy-induced hypertension (p<0.0001). Conclusion: Our study observed significant modifiable risk factors like weight gain, weight, hemoglobin, and anemia among mothers with low birth weight babies. If we focus on raising awareness surrounding these risk factors, there may be an improvement in the birth weight of babies in this population.


2006 ◽  
Vol 25 (8) ◽  
pp. 447-452 ◽  
Author(s):  
R Rahimi ◽  
S Nikfar ◽  
M Abdollahi

Inhaled corticosteroids (ICs) are the drug of choice for asthmatic women during pregnancy, but the results on the effects of these medications on obstetrical and perinatal outcomes are not conclusive. Meta-analysis is the statistical analysis of a collection of analysis results from individual studies for the purpose of integrating the findings. Meta-analysis techniques are necessary because only summary statistics are available in the literature. In order to determine the risk of exposure to ICs, we pooled data from all clinical studies that evaluated the pregnancy and perinatal outcomes in women exposed to this group of drugs during pregnancy by the meta-analytic technique. PUBMED, OVID, EMBASE and SCOPUS databases were searched for studies that investigated birth outcome following exposure to ICs during pregnancy. Data were collected from 1997 to 2005 (up to 31 December). Types of outcome investigated were major malformations, pre-term delivery, low birth weight and pregnancy-induced hypertension. The criteria for inclusion of studies in this meta-analysis were exposure of women to any therapeutic dosage of any ICs (fluticasone, beclomethasone, budesonide, triamcinolone and flunisolide) during pregnancy. The results showed that ICs do not increase the risk of major malformations, preterm delivery, low birth weight and pregnancy-induced hypertension. In conclusion, ICs do not increase the rates of any obstetrical outcomes investigated in the present study and interestingly improve the symptoms and are helpful in the management of asthma and thus can be used comfortably during pregnancy.


2020 ◽  
Vol 2020 ◽  
pp. 1-8 ◽  
Author(s):  
Ayele Mamo Abebe ◽  
Girma Wogie Fitie ◽  
Desalegn Abebaw Jember ◽  
Mihretab Mehari Reda ◽  
Getu Engida Wake

Introduction. One of the major public health issues across the whole world these days is teenage pregnancy which is defined as being pregnant in the age ranging from 13–19 years. About 11% of all births which occurred worldwide accounted for girls aged 15 to 19 years. From these, 95% teenage deliveries occur in low- and middle-income countries. World health 2014 statistics show that complications during pregnancy and childbirth are the second cause of death for 15–19-year-old girls globally. The aim of this study was to determine adverse obstetrical and perinatal outcomes of teenage pregnancy among deliveries at Lemlem Karl General Hospital, Tigray, Ethiopia, 2018. Result. This study result showed that 17.5% of the teenagers and 6.8% of the adults deliver low birth weight neonates. From the total teenage mothers, about thirty-five (11.3%) of them had developed pregnancy-induced hypertension, whereas about thirteen (4.2%) of adults develop pregnancy-induced hypertension. Regarding cesarean delivery, forty (12.9%) of those teenage mothers deliver by a cesarean section while 58 (18%) of the adult mothers deliver by cesarean delivery. Teenage pregnancy was significantly associated with adverse obstetric and perinatal outcomes, a cesarean delivery (AOR: 0.57; 95% CI, 0.36–0.90), episiotomy (AOR: 2.01; 95% CI, 1.25–3.39), and low birth weight (AOR: 2.22; 95% CI, 1.13–4.36), and premature delivery were 2.87 (1.49–5.52). This study shows that adverse obstetric and perinatal outcomes were significantly associated with teenagers than adult mothers. Therefore, giving health education on focused ANC is very important to bring change to the teenager at this study area.


2008 ◽  
Vol 20 (2) ◽  
pp. 152-158 ◽  
Author(s):  
Latifah A. Rahman ◽  
Noran N. Hairi ◽  
Nooriah Salleh

The purpose of this study was to investigate the association between pregnancy-induced hypertension and low birth weight. A population-based case control study was conducted. Antenatal mothers who attended the government health centers in the district of Kuala Muda, Kedah, Malaysia from June 2003 to May 2004 were recruited. Cases were 312 mothers who delivered low birth weight babies, and controls were 312 mothers who delivered normal birth weight babies. Face-to-face interviews using a structured questionnaire and a review of medical records were carried out. After controlling for important confounders such as gestational age at delivery, maternal age, ethnicity, education, parity, and previous history of abortion, pregnancy-induced hypertension was found to be an independent risk factor (adjusted odds ratio = 5.06; 95% confidence interval: 2.63, 9.71) for low birth weight. There was a significant association of pregnancy-induced hypertension with low birth weight. Women who delivered low birth weight babies were 5 times more likely to have had pregnancy-induced hypertension.


2020 ◽  
Vol 7 (4) ◽  
pp. 865
Author(s):  
Madhusmita Pradhan ◽  
Jyotiranjan Champatiray ◽  
Kishore V. S.

Background: Though pregnancy induced hypertension is a worldwide problem, it is more prevalent in developing countries particularly south east Asian and African countries. It contributes to 20% of perinatal death and 40-50% of low birth weight babies in India. Fetal salvage is also an important consideration in providing quality care. Low dose aspirin given between 12 weeks to 28 weeks of gestational age in high-risk women at Developing Pregnancy Induced Hypertension (PIH) is anticipated to prevent the development of PIH and complications that arises especially those regarding maternal and fetal mortality due to PIH.Methods: This prospective randomized controlled trial was conducted in the dept of O and G, SCB MC and Hospital, Cuttack during November 2018 to October 2019. Pregnant women between the gestational age of 13 to 28 week were screened for risk factors and included in this study. Low dose aspirin of 60 mg daily till delivery was given to pregnant women who consented to be a part of study randomly with the other group taking placebo.Results: Incidence of IUGR babies in low dose aspirin treated mothers was as low as 1%. Incidence of LBW babies is lower in low dose aspirin treated mothers than with those who were not treated. Mean birth weight in cases was 2780 gm±352 gm vs control 2592 gm±483 gm. There is increased incidence of still birth in high risk group not treated with aspirin. No significant difference in reducing incidence premature deliveries between case and control.Conclusions: Low dose aspirin has a definite role in the prevention of PIH in high risk pregnancy and its complication like IUGR and low birth weight. Low dose aspirin reduces the incidence of PIH. Low dose aspirin can be considered a safe drug without any deleterious side effect for mother and the fetus. Benefits of prevention of PIH, justifies its administration in women at high risk.


2015 ◽  
Vol 05 (01) ◽  
pp. 062-067
Author(s):  
Prathima P. ◽  
S Anuchitra

Abstract Title : Correlation between BMI and pregnancy Outcome among postnatal mothers with pregnancy Induced hypertension in selected hospital Bangalore. Objectives: To identify and correlate BMI and pregnancy Outcome among postnatal mothers with pregnancy Induced hypertension. Method: A non experimental correlation design was utilized among 80 postnatal mothers who were diagnosed as Pregnancy induced hypertension during their antenatal period selected as samples by using purposive sampling technique. Demographic data were collected by interview method, their BMI was calculated, pregnancy outcomes were identified from records by using an outcome checklist. Results : Underweight mothers had low birth weight babies and received NICU care. Among normal weight mothers 17.5 % delivered by LSCS, 15% babies were low birth weight babies 12.5 were preterm babies among them 10% received NICU care. In the overweight group 18.75% undergone LSCS, 18.75% were LBW and 1.25% VLBW, 8.75% babies were preterm, 12.5% newborn received NICU care. Among Obese mothers 8.75% delivered by LSCS, 6.25% of LBW babies, 5% were preterm and all of them received NICU care. There is a positive correlation between BMI and diagnosis and type of delivery. Significant at .01 and .05 Level (p value .008 and .019 respectively). Negative correlation between birth weight and diagnosis and gestational age. r = -.499 significant at .01 level (p value .000) Conclusion: Obesity and under weight is a leading, preventable cause of mortality worldwide. Preeclampsia increases maternal and perinatal morbidity and mortality rates. All women who are in reproductive age group and under risk to develop pregnancy induced hypertension need to be educated about to maintenance of normal weight before pregnancy. Nurses have more responsibility on creating awareness among women how to maintain normal weight to avoid development of complications to the mother and newborn.


2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
Eyasu Alem Lake ◽  
Robera Olana Fite

Background. Birth weight has a vital role in determining newborns survival in vulnerable conditions. Low birth weight is associated with fetal and neonatal morbidity and mortality, impairment of growth and development and also chronic disease later in life. This study was aimed to assess the magnitude of low birth weight and its determinants in Wolaita Sodo University teaching and referral hospital, southern Ethiopia. Methods. Institution based cross-sectional study was conducted from November to December 2018. Systematic random sampling technique was used to select study participants. Data was collected by interviewing mothers through structured questionnaire and reviewing neonates' medical records using a checklist. Multivariable binary logistic regression analyses were employed to identify factors associated with neonatal jaundice. Results. The proportion of low birth weight in the study area was found to be 15.8% (95% CI 11.7-19.9). Being primiparity [AOR=5.798; 95% (1.572-21.377)], anemia during pregnancy [AOR=3.808; 95% (1.513-9.586)], pregnancy induced hypertension [AOR= 6.955; 95% (2.386- 20.275)], intake herbal medication during pregnancy [AOR=35.762; 95% (4.571-279.764)], drinking alcohol during pregnancy [AOR=8.111; 95% (2.359-27. 895)] were predictors of low birth weight. Conclusion. The proportion of low birth weight among newborns delivered at Wolaita Sodo University teaching and referral hospital was comparable with the global prevalence of low birth weight. Parity, anemia, alcohol, herbal medication, and pregnancy-induced hypertension were significantly associated with low birth weight.


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