scholarly journals The Harrison Lecture. The history and role of Mycoplasma genitalium in sexually transmitted diseases.

1995 ◽  
Vol 71 (1) ◽  
pp. 1-8 ◽  
Author(s):  
D Taylor-Robinson
Keyword(s):  
Sexually Transmitted Diseases ◽  
Mycoplasma Genitalium ◽  
Sexually Transmitted

Role of the Pediatrician in Management of Sexually Transmitted Diseases in Children and Adolescents

PEDIATRICS ◽  
1987 ◽  
Vol 79 (3) ◽  
pp. 454-456
Author(s):  
Keyword(s):  
Young People ◽  
Children And Adolescents ◽  
Sexually Transmitted Diseases ◽  
Sexual Intercourse ◽  
Contraceptive Methods ◽  
Delay In Diagnosis ◽  
Sexually Transmitted ◽  
Adolescent Population ◽  
Increased Risk

Approximately half of all American adolescents have experienced sexual intercourse by age 17 years.1 The second highest rate of reported gonococcal infections (1,229 cases per 100,000 persons) occurs in 15- to 19-year-old adolescents. This increased risk in the adolescent population has been associated with the greater number of young people having sexual intercourse, the infrequent use of barrier contraceptive methods, the obstacles to prompt medical care that teenagers face, with consequent delay in diagnosis and further spread of the disease, and the large number of asymptomatic carriers.2 The pediatrician has an important responsibility for providing sexuality-related care to children and adolescents.2-4

scholarly journals MgpB Types among Mycoplasma genitalium Strains from Men Who Have Sex with Men in Berlin, Germany, 2016–2018

Pathogens ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. 12 ◽  
Author(s):  
Roger Dumke ◽  
Marcos Rust ◽  
Tobias Glaunsinger
Keyword(s):  
Sexually Transmitted Diseases ◽  
Mycoplasma Genitalium ◽  
Clinical Samples ◽  
Genome Region ◽  
Sexually Transmitted ◽  
Gene Coding ◽  
A Cell ◽  
Different Populations ◽  
Sex With Men

Mycoplasma genitalium is a cell wall-less bacterium causing urethritis and other sexually transmitted diseases. Despite a strongly conserved genome, strains in clinical samples can be typed by different methods. To obtain data from the risk population of men having sex with men, we analyzed the typing region in the gene coding for the MgpB adhesin of M. genitalium first in 163 and 45 follow-up samples among patients of two specialized practices in Berlin, Germany. Strains belong to 43 different mgpB types emphasizing the diversity of the genome region. With respect to 133 types previously described, 27 new types were found. However, the majority of strains (64.4%) were assigned to types 4, 6, 113, and 108, respectively. A correlation between mgpB type and the occurrence of mutations associated with macrolide and quinolone resistance was not demonstrated. Investigation of follow-up samples from 35 patients confirmed the same mgpB and, additionally, MG_309 types in 25 cases. In 10 cases, differences between types in subsequent samples indicated an infection with a genetically different strain in the period between samplings. MgpB/MG_309 typing is a useful method to compare M. genitalium strains in samples of individual patients as well as those circulating in different populations

Coinfection with chlamydia and gonorrhoea among pregnant women with bacterial vaginosis

1996 ◽  
Vol 7 (1) ◽  
pp. 61-64 ◽  
Author(s):  
M. R. Joesoef ◽  
G. Wiknjosastro ◽  
W. Norojono ◽  
H. Sumampouw ◽  
M. Linnan ◽  
...  
Keyword(s):  
Bacterial Vaginosis ◽  
Pregnant Women ◽  
Sexually Transmitted Diseases ◽  
Economic Status ◽  
Sexual Transmission ◽  
Fold Increase ◽  
Gram Stain ◽  
Sexually Transmitted ◽  
Socio Economic Status

The role of sexual transmission of microorganisms in bacterial vaginosis (BV) is controversial. If sexual intercourse were a risk factor for BV, then we would expect that women with BV would also be coinfected with other sexually transmitted diseases (STD). We investigated the prevalence of STD among pregnant women of low socio-economic status with bacterial vaginosis in Indonesia. Among these women, 23.3% had at least one STD (chlamydia, gonorrhoea, syphilis or trichomoniasis). Chlamydial infection was the most prevalent (19.5%), followed by trichomoniasis (3.8%), gonorrhoea (3.2%) and syphilis (0.4%). Compared to the rates of STD observed in a previous study of all pregnant women (with or without BV) in Indonesia, pregnant women with BV have more than a 2-fold increase in chlamydia (19.5% vs 8.2%) and a 6-fold increase in gonorrhoea (3.2% vs 0.5%). Because detection of BV by Gram stain is easy to perform and economical, detection of BV has potential as a prescreening marker for chlamydia and gonorrhoea among asymptomatic pregnant women of low socio-economic status in Indonesia. Further work is needed to evaluate the usefulness of BV as a prescreening marker for chlamydia and gonorrhoea.

scholarly journals T Cells in the Female Reproductive Tract Can Both Block and Facilitate HIV Transmission

2019 ◽  
Vol 15 (1) ◽  
pp. 36-40
Author(s):  
Christopher J. Miller ◽  
Ronald S. Veazey
Keyword(s):  
T Cells ◽  
Immune System ◽  
Sexually Transmitted Diseases ◽  
Reproductive Tract ◽  
Hiv Transmission ◽  
Female Reproductive Tract ◽  
Central Importance ◽  
Sexually Transmitted ◽  
Anti Hiv

Because HIV is sexually transmitted, there is considerable interest in defining the nature of anti-HIV immunity in the female reproductive tract (FRT) and in developing ways to elicit antiviral immunity in the FRT through vaccination. Although it is assumed that the mucosal immune system of the FRT is of central importance for protection against sexually transmitted diseases, including HIV, this arm of the immune system has only recently been studied. Here, we provide a brief review of the role of T cells in the FRT in blocking and facilitating HIV transmission.

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