scholarly journals Effect of inguinal hernia on the thickness and blood flow of spermatic cord in boys

2019 ◽  
Vol 2 (2) ◽  
pp. e000030
Author(s):  
Shoujiang Huang ◽  
Canping Li ◽  
Xiuzhen Yang ◽  
Jianfeng Liang ◽  
Dongpi Wang
Keyword(s):  
Blood Flow ◽  
Inguinal Hernia ◽  
Spermatic Cord ◽  
Peak Systolic Velocity ◽  
Control Group ◽  
Pampiniform Plexus ◽  
Significant Difference ◽  
Highly Correlated ◽  
And Control ◽  
The Relationship

ObjectiveTo evaluate the effect of inguinal hernia (IH) on the spermatic cord using spermatic cord ultrasonography (SCU).MethodsFrom January 2016 to January 2017, boys with IH who received SCU at the start of open herniorrhaphy (OH) were enrolled in this study. The age and weight at SCU, width of the spermatic cord (SC-W), peak systolic velocity (PSV) in the spermatic artery (SA-PSV) and velocity in the pampiniform plexus (PP-V), and the interval between the initial and the second OH in boys with metachronous inguinal hernia (MIH) were recorded, and the relationship among them was studied. Boys with unilateral IH comprised the IH group, and boys with MIH comprised the MIH group. Boys with polydactylism served as the control. One-way analysis of variance tested the differences among groups. Spearman’s r tested the relationship between SC-W in the MIH group and the interval.ResultsA total of 80 boys were enrolled in this study (IH group 29, MIH group 26, and control group 25). SA-PSV and PP-V in the hernia side were faster and slower than the control, respectively. There was no significant difference in PP-V and SA-PSV of the treated side in the MIH group and in the control group. After herniorrhaphy, SC-W was tapered down to normal size. SC-W, SA-PSV, and PP-V in the treated side were all highly correlated to the interval in a curvilinear manner.ConclusionPSV was positively correlated with SC-W in boys with IH, and PP-V was negatively correlated; herniorrhaphy could reverse the impairment.

Plasma kisspeptin and ghrelin levels in puberty variant cases

2017 ◽  
Vol 30 (5) ◽  
Author(s):  
Erdal Kurnaz ◽  
Yaşar Şen ◽  
Süleyman Aydın
Keyword(s):  
Serum Levels ◽  
Control Group ◽  
Control Groups ◽  
Premature Thelarche ◽  
Premature Adrenarche ◽  
Significant Difference ◽  
And Gender ◽  
And Control ◽  
Relationship Of ◽  
The Relationship

AbstractBackground:The aim of this study was to determine the serum levels of kisspeptin and ghrelin (GAH), as well as the relationship of these two peptides with each other in premature thelarche (PT) and premature adrenarche (PA) cases and to investigate the possibility of using these peptides as markers in the differentiation of puberty disorders.Methods:A PT group aged 1–8 years (n = 40), a PA group aged 1–9 years (n = 23, female/male = 20/3) and control groups consistent with each of the previous groups in terms of age and gender were created for the study. Kisspeptin and ghrelin levels were measured with ELISA methods from blood samples drawn while fasting in the morning.Results:When the PT group was compared with the controls, the plasma kisspeptin levels of the cases were significantly higher than the control group (165.47 ± 15.45 pmol/L, 96.82 ± 12.33 pmol/L, p = 0.005, respectively). Kisspeptin levels in the PA group did not show a difference with the control group (121.36 ± 17.99 pmol/L, 95.52 ± 11.54 pmol/L, p = 0.249, respectively). No significant difference could be found when GAH levels in the PT and PA groups were compared with controls. No significant correlation was found between kisspeptin and GAH levels in the PT and PA groups.Conclusions:Our results indicate that kisspeptin plays an important role in the PT, but GAH is not associated with puberty disorders.

Renal Blood Flow in Twins

1998 ◽  
Vol 47 (3-4) ◽  
pp. 161-169
Author(s):  
M. K. Kornacka ◽  
E. Burzyńska ◽  
J. Gadzinowski
Keyword(s):  
Blood Flow ◽  
Renal Blood Flow ◽  
Gestational Age ◽  
Clinical Symptoms ◽  
Mean Value ◽  
Control Group ◽  
Left Renal Artery ◽  
Mean Velocity ◽  
Significant Difference ◽  
And Control

AbstractThe aim of this preliminary study was the estimation of renal blood flow in 16 premature newborns from twin pregnancies with mean body weight 1270 g and mean gestational age 29 weeks.In control group we have 16 singleton newborns with mean gestational age 29 weeks and mean birth weight 1240 g. In both intervention and control group we have the similar clinical symptoms. The renal blood flow was carried out in the first day of life with the Acuson 128 XP Colour Doppler using the 6 and 7 MHz linear transducer. The renal blood flow parameters-PI, RI, Vmax, Vmin Vmean were measured in right and left renal arteries in theirs courses from the aorta to the renal hilus, by color sinal. In the investigation group the mean value of RI in right and left renal artery was 0,88. Mean PI in right vessel was 1,67 and in left 1,56. Mean V min in right and in left artery was 0,03 and mean V max in right artery was 0,34 and in left 0,33. Mean value of mean velocity in right vessels was 0,18 and in left 0,19.In control group we observed in right artery mean value of PI 1,74 and in left 1,6. Mean RI was 0,86 and 0,86 in right vessel in left vessel. Mean V min was 0,05 in right and 0,04 in left artery. Mean V max was 0,37 in right and 0,34 in left artery. Mean value of V mean was 0,19 in right artery and 0,18 in left artery.Using the student, Mann-Whitney and Shapiro-Wilk tests we have not observed statistically significant difference of Doppler parameters between control and investigation group and between the left and right artery. Although in newborns with broad PDA we noted significant higher value of RI (0,97, 0,98) than in newborns without PDA (0,78, 0,81).

scholarly journals Transcranial doppler findings in basilar artery dolichoectasia: a case control study

2021 ◽  
Vol 9 (4) ◽  
pp. 177-188
Author(s):  
Zaid Hussein ◽  
Keyword(s):  
Blood Flow ◽  
Basilar Artery ◽  
Transcranial Doppler ◽  
Case Control Study ◽  
Peak Systolic Velocity ◽  
Case Control ◽  
Control Group ◽  
Stroke Patients ◽  
Significant Difference ◽  
Control Study

Basilar artery dolichoectasia (BAD) is a disorder characterized by dilatation, elongation and tortuosity of the basilar artery. Transcranial Doppler ultrasound (TCD) is a useful tool that can detect blood flow in intracranial vessels including basilar artery (BA). Few studies have been conducted on blood flow changes in BAD. This study was conducted to evaluate the Doppler parameters in dolichoectatic BA and to assess if there is any difference in TCD findings between stroke and non-stroke BAD patients. A case-control study was conducted on 35 patients diagnosed with BAD (26 male, 9 female) and 35 age- and gender-matched control group (without BAD) at the Middle Euphrates Neuroscience Center, Al-Sader Medical City, Al-Najaf, Iraq. Dolichoectasia was diagnosed on non-enhanced brain CT scan using established imaging criteria according to Dan Deng et al criteria. Doppler flow for control and stroke cases was recorded. The parameters measured on TCD were peak systolic velocity (PSV), end diastolic velocity (EDV) mean blood velocity (MBV), pulsatility index (PI) and resistive index (RI). After logistic regression for adjustment for the significant confounders, there was statistically significant difference in Doppler parameters between both groups including decrease in each of PSV, EDV and MBV while both PI and RI weren’t statistically significant. Among BAD patients, there was statistically significant difference in all TCD parameters between stroke and non-stroke patients (PSV EDV, MBV, PI and RI). BAD was associated with a decrease in flow velocities as measured by TCD. Furthermore, among BAD patients, those with stroke had lower values for all Doppler parameters than non-stroke patients.

scholarly journals Polymorphisms of the uridine-diphosphoglucuronosyltransferase 1A1 gene and coronary artery disease

2008 ◽  
Vol 13 (1) ◽  
pp. 1-10 ◽  
Author(s):  
Chia-Jung Hsieh ◽  
Meng-Jung Chen ◽  
Yung-Liang Liao ◽  
Tung-Nan Liao
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Control Group ◽  
Ugt1a1 Gene ◽  
Coding Regions ◽  
Significant Difference ◽  
Polymerase Chain ◽  
Artery Disease ◽  
Highly Correlated ◽  
The Relationship

AbstractBilirubin, an antioxidant in the blood, plays a role in protection from atherosclerosis. The level of bilirubin is highly correlated to the incidence of coronary artery disease (CAD). Unconjugated bilirubin is conjugated with glucuronic acid through the reaction of uridine 5′-diphosphate-glucuronosyl transferase 1A1 (UGT1A1). The interactions of CAD and the variations in the coding regions of the UGT1A1 gene have never been evaluated. The purpose of this study was to analyze the influence of the UGT1A1 variant on the incidence of CAD. There were 135 participants in this study: 61 in the experimental group, who had CAD, and 74 in the control group, who did not have CAD. The blood samples from all 135 participants were collected and assayed to clarify the relationship between bilirubin and CAD. The assay of the polymerase chain reaction and the sequence of the UGT1A1 gene were examined to find the gene’s polymorphisms. The bilirubin levels for the participants in the control group were significantly higher than for the patients in the CAD group. Although the concentration of bilirubin in the UGT1A1 variant was higher than the wild type for the patients in the CAD group, there was no significant difference in the polymorphism of UGT1A1 between the patients in the CAD group and the participants in the control group.

scholarly journals Olfactory Cleft Opacification in COVID-19 Related Smell Loss: CT Findings and Correlation With Objective Testing

2021 ◽  
pp. 014556132110112
Author(s):  
Erkan Yıldız ◽  
Aydın Balcı ◽  
Okan Selendili ◽  
Selçuk Kuzu
Keyword(s):  
Control Group ◽  
Sudden Loss ◽  
Olfactory Cleft ◽  
Olfactory Loss ◽  
Olfactory Test ◽  
Ct Findings ◽  
Clinical Research Center ◽  
Significant Difference ◽  
And Control ◽  
The Relationship

Objectives: Besides the common symptoms of the coronavirus disease 2019 (COVID-19) including fever, shortness of breath, and cough, a “sudden loss of smell” has recently been added as a diagnostic symptom. The relationship between paranasal sinus computed tomography (PNS CT) and sudden loss of smell in COVID-19 was examined. Materials and Methods: Two groups were selected for the study, the COVID-19 and the control groups. The control group consisted of 40 patients who applied to our clinic with headache and therefore underwent PNS CT. The other group consisted of 40 patients with COVID-19 who were diagnosed with sudden loss of smell with the Connecticut Chemosensory Clinical Research Center (CCCRC) olfactory test. Clinical and demographic characteristics, tomography results, and olfactory test scores of patients with COVID-19 loss of smell and control group patients were recorded. The relationship between CT changes in the olfactory cleft and the degree of loss of smell was evaluated. The “Opacification in the olfactory cleft” was accepted as a positive CT finding. Results: Comparison of patients with COVID-19 who had a loss of smell and the control group indicated that a significant difference was observed in terms of CT findings ( P = .022). When we evaluated the paranasal CTs obtained from our patients with loss of smell, the CT of 13 patients showed pathological findings ( P < .05). As the COVID-19 progressed (pneumonia and respiratory failure), the degree of loss of smell increased ( P < .05). A statistically significant relationship was found between the CCCRC score and the presence of PNS CT findings ( P = .0012). Conclusion: The PNS CT findings are significant in patients with COVID-19 with a loss of smell and were significantly associated with the degree of loss of smell. In patients with olfactory loss due to COVID-19, PNS CT can help in diagnosis. However, for this imaging to be diagnostic, a larger patient series is needed.

scholarly journals Transcranial doppler findings in basilar artery dolichoectasia: a case control study

2021 ◽  
Vol 9 (4) ◽  
pp. 177-188
Keyword(s):  
Blood Flow ◽  
Basilar Artery ◽  
Transcranial Doppler ◽  
Case Control Study ◽  
Peak Systolic Velocity ◽  
Case Control ◽  
Control Group ◽  
Stroke Patients ◽  
Significant Difference ◽  
Control Study

Basilar artery dolichoectasia (BAD) is a disorder characterized by dilatation, elongation and tortuosity of the basilar artery. Transcranial Doppler ultrasound (TCD) is a useful tool that can detect blood flow in intracranial vessels including basilar artery (BA). Few studies have been conducted on blood flow changes in BAD. This study was conducted to evaluate the Doppler parameters in dolichoectatic BA and to assess if there is any difference in TCD findings between stroke and non-stroke BAD patients. A case-control study was conducted on 35 patients diagnosed with BAD (26 male, 9 female) and 35 age- and gender-matched control group (without BAD) at the Middle Euphrates Neuroscience Center, Al-Sader Medical City, Al-Najaf, Iraq. Dolichoectasia was diagnosed on non-enhanced brain CT scan using established imaging criteria according to Dan Deng et al criteria. Doppler flow for control and stroke cases was recorded. The parameters measured on TCD were peak systolic velocity (PSV), end diastolic velocity (EDV) mean blood velocity (MBV), pulsatility index (PI) and resistive index (RI). After logistic regression for adjustment for the significant confounders, there was statistically significant difference in Doppler parameters between both groups including decrease in each of PSV, EDV and MBV while both PI and RI weren’t statistically significant. Among BAD patients, there was statistically significant difference in all TCD parameters between stroke and non-stroke patients (PSV EDV, MBV, PI and RI). BAD was associated with a decrease in flow velocities as measured by TCD. Furthermore, among BAD patients, those with stroke had lower values for all Doppler parameters than non-stroke patients.

scholarly journals Increased mast cells in endocervical smears of women with dysmenorrhea

CytoJournal ◽  
2018 ◽  
Vol 15 ◽  
pp. 27
Author(s):  
Shunichiro Tsuji ◽  
Kiyoshi Tsuji ◽  
Hirokuni Otsuka ◽  
Takashi Murakami
Keyword(s):  
Methylene Blue ◽  
Mast Cells ◽  
Median Number ◽  
Interquartile Range ◽  
Control Group ◽  
Control Groups ◽  
Significant Difference ◽  
Peritoneal Endometriosis ◽  
And Control ◽  
The Relationship

Background: Mast cells are observed in peritoneal endometriosis which causes dysmenorrhea. However, there is no report about the relationship between endocervical mast cells and dysmenorrhea. The aim of this study is to evaluate the relationship using endocervical smears. Materials and Methods: Between January 2016 and June 2016, patients filled out a questionnaire regarding dysmenorrhea and were classified into the dysmenorrhea or the control group (without dysmenorrhea). Patients underwent endocervical brushing and endocervical smears were obtained. The smears were stained with methylene blue to detect mast cells. The number of mast cells per slide was counted by microscopy and recorded. Results: Eighty-nine patients were enrolled in this study (dysmenorrhea group, 34; control group, 55). The median number of mast cells present in the endocervical one slides was 35 (interquartile range, 17–58) and 2 (interquartile range, 0–6) in the dysmenorrhea and control groups, respectively. There was a significant difference in the number of mast cells between the two groups (P < 0.0001). Conclusion: More mast cells were observed in the endocervical smears of women with dysmenorrhea than in those of women without dysmenorrhea.

Association between -174 G/C polymorphism of interleukin-6 gene and alcoholism

2003 ◽  
Vol 15 (5) ◽  
pp. 257-261 ◽  
Author(s):  
Omar Šerý ◽  
Renáta Hladilová ◽  
Miroslav Novotný ◽  
Hana Hríbková ◽  
Vladimír Znojil ◽  
...  
Keyword(s):  
Alcohol Dependence ◽  
Association Study ◽  
Allele Frequency ◽  
Interleukin 6 ◽  
Control Group ◽  
Control Subjects ◽  
First Finding ◽  
Significant Difference ◽  
And Control ◽  
The Relationship

Objectives:IL-6 plays the role as a physiological neuromodulator involved in dopaminergic, serotonergic and other neurotransmissions. The aim of the present association study was to examine the effect of the G/C -174 polymorphism of the IL-6 gene on disposition to alcoholism.Methods:We investigated the relationship between the G/C -174 polymorphism of the IL-6 gene and alcohol dependence in 281 alcoholics and 242 control subjects.Results:The significant difference in G allele frequency between alcoholic group (0.52) and control group (0.59) was found (P < 0.03).Conclusion:To our knowledge, this is the first finding providing evidence for an association between alcoholism and the polymorphism of the IL-6 gene. The background of the relationship between the IL-6 gene and alcoholism is discussed.

Effects of SR-BI rs5888 and rs4238001 variations on hypertension

2019 ◽  
Vol 44 (4) ◽  
pp. 549-553
Author(s):  
Burcu Çaykara ◽  
Hani Alsaadoni ◽  
Halime Hanım Pençe ◽  
Sadrettin Pençe ◽  
Hülya Yılmaz Aydoğan ◽  
...  
Keyword(s):  
Vessel Wall ◽  
Quantitative Polymerase Chain Reaction ◽  
Scavenger Receptor ◽  
Control Group ◽  
Type I ◽  
Significant Difference ◽  
Class B ◽  
Polymerase Chain ◽  
And Control ◽  
The Relationship

Abstract Background Scavenger receptor class B, type I (SR-BI), involved in reverse cholesterol pathway, is a multilipoprotein receptor and capable of binding HDL, LDL and VLDL. SR-BI may contribute to the development of hypertension due to accumulation of cholesterol in the vessel wall via transporting lipoproteins. Therefore, it was aimed to investigate the relationship between SR-BI rs5888 and rs4238001 variants in the patient with hypertension. Materials and methods Seventy three subjects diagnosed with hypertension and 76 healthy subjects constituted the patient and control group, respectively. Genomic DNA was isolated from peripheral blood samples and a real-time quantitative polymerase chain reaction protocol was performed to detect variations of rs5888 and rs4238001. The results were analyzed with the SPSS 22 program and p < 0.05 was considered statistically significant. Results and discussion SR-BI rs4238001 variation did not show significant difference between patient and control group (p > 0.05). In the SR-BI rs5888 variation; normal homozygous CC and heterozygous CT carriers had an average 2-fold lower risk of hypertension than those carrying the TT genotype (p < 0.05). Conclusion SR-BI rs5888 TT variant may increase hypertension risk by reducing lipid transport to the liver from the vessel wall.

The ACTN3 XX Genotype’s Underrepresentation in Japanese Elite Wrestlers

2013 ◽  
Vol 8 (1) ◽  
pp. 57-61 ◽  
Author(s):  
Naoki Kikuchi ◽  
Dai Ueda ◽  
Seok-ki Min ◽  
Koichi Nakazato ◽  
Shoji Igawa
Keyword(s):  
Athletic Performance ◽  
Olympic Games ◽  
National Level ◽  
Control Group ◽  
International Level ◽  
Control Groups ◽  
Athletic Status ◽  
Significant Difference ◽  
And Control ◽  
The Relationship

Purpose:To examine the relationship between ACTN3 polymorphisms and level of athletic performance in Japanese wrestlers.Methods:The control group consisted of 243 healthy Japanese individuals. The authors divided 135 wrestlers into 3 groups based on their results in national or international competitions. They classified as elite 24 wrestlers who had placed in the top 8 in a world championship or participated in Olympic games, 28 wrestlers who had participated in world championships or become champions in Japan’s national championships were classified as subelite, and 83 wrestlers were classified as national (N-W, ie, national-level wrestler). In addition, the authors combined the elite and subelite to form the classification international-level wrestlers (I-W).Results:The frequency of the null X allele and the XX genotype were significantly lower in the I-W group than in the control group. However, there was no significant difference in ACTN3 genotype or allele frequency between the N-W and control groups. The frequency of the ACTN3 XX genotype in the elite groups was lower than that of all groups, and a linear tendency was observed between ACTN3 XX genotype and athletic status.Conclusions:In conclusion, the data indicated that ACTN3 polymorphisms were related to athletic performance in Japanese wrestlers.

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