Extensor Carpi Ulnaris Tendon Anatomy May Mimic Tears

2019 ◽  
Vol 24 (02) ◽  
pp. 175-179
Author(s):  
John Erickson ◽  
Ariel Kwart ◽  
S. Steven Yang
Keyword(s):  
Linear Regression ◽  
Insertion Site ◽  
Upper Extremities ◽  
Statistical Correlations ◽  
Extensor Carpi Ulnaris ◽  
Distal Edge ◽  
Longitudinal Split ◽  
The Mean ◽  
Tendon Insertion ◽  
Distal Tendon

Background: Asymptomatic, incidental extensor carpi ulnaris (ECU) tendon abnormalities are frequently noted on imaging studies of the wrist. The aim of this investigation was to determine if variations in gross tendon anatomy existed that could possibly account for these findings on MRI and ultrasound (US) imaging. Methods: The upper extremities of eleven (6 male and 5 female) formalin preserved cadavers were dissected and examined under loupe magnification with attention to the dorsal-ulnar wrist and hand and the ECU tendon. The tendons were inspected for anatomic variations, degenerative changes, and any other pathologies. The presence of intra-tendinous splits arising within the ECU tendon was noted and measured. The distances of the splits from the distal tendon insertion and the edge of the extensor retinaculum were recorded. Statistical correlations between age and the tendon splits were considered using R-squared to assess a linear regression. Results: 17 ECU tendons were dissected and examined, and 5 ECU tendons were excluded due to poor preservation of that upper extremity; all five were right sided upper extremities. Eleven of the 17 specimens demonstrated at least one split in the distal tendon: Seven had 1 split, 1 had 2 splits, and 3 had 3 splits. The mean length of the tendon split was 3.52 cm. The mean distance of the distal edge of the split to the tendon insertion site was 2.4 cm. A linear regression was calculated and showed no correlation between age and number of tendon splits. Conclusions: 64% of specimens showed a longitudinal split in the distal ECU tendon. The location of these frequent splits corresponds to imaging abnormalities on MRI and US in prior studies.

scholarly journals P170 The validity and utility of the SLE-key® rule-out serological test when applied in a selected cohort of patients with SLE and other connective tissue diseases

Rheumatology ◽  
2021 ◽  
Vol 60 (Supplement_1) ◽  
Author(s):  
Sheilla Achieng ◽  
John A Reynolds ◽  
Ian N Bruce ◽  
Marwan Bukhari
Keyword(s):  
Linear Regression ◽  
Connective Tissue ◽  
Connective Tissue Disease ◽  
Negative Correlation ◽  
Connective Tissue Diseases ◽  
Inflammatory Myositis ◽  
The Mean ◽  
Negative Rule ◽  
Spearman’S Correlation ◽  
Rule Out

Abstract Background/Aims  We aimed to establish the validity of the SLE-key® rule-out test and analyse its utility in distinguishing systemic lupus erythematosus (SLE) from other autoimmune rheumatic connective tissue diseases. Methods  We used data from the Lupus Extended Autoimmune Phenotype (LEAP) study, which included a representative cross-sectional sample of patients with a variety of rheumatic connective tissue diseases, including SLE, mixed connective tissue disease (MCTD), inflammatory myositis, systemic sclerosis, primary Sjögren’s syndrome and undifferentiated connective tissue disease (UCTD). The modified 1997 ACR criteria were used to classify patients with SLE. Banked serum samples were sent to Immune-Array’s CLIA- certified laboratory Veracis (Richmond, VA) for testing. Patients were assigned test scores between 0 and 1 where a score of 0 was considered a negative rule-out test (i.e. SLE cannot be excluded) whilst a score of 1 was assigned for a positive rule-out test (i.e. SLE excluded). Performance measures were used to assess the test’s validity and measures of association determined using linear regression and Spearman’s correlation. Results  Our study included a total of 155 patients of whom 66 had SLE. The mean age in the SLE group was 44.2 years (SD 13.04). 146 patients (94.1%) were female. 84 (54.2%) patients from the entire cohort had ACR SLE scores of ≤ 3 whilst 71 (45.8%) had ACR SLE scores ≥ 4. The mean ACR SLE total score for the SLE patients was 4.85 (SD 1.67), ranging from 2 to 8, with mean disease duration of 12.9 years. The Sensitivity of the SLE-Key® Rule-Out test in diagnosing SLE from other connective tissue diseases was 54.5%, specificity was 44.9%, PPV 42.4% and NPV 57.1 %. 45% of the SLE patients had a positive rule-out test. SLE could not be ruled out in 73% of the MCTD patients whilst 51% of the UCTD patients had a positive Rule-Out test and >85% of the inflammatory myositis patients had a negative rule-out test. ROC analysis generated an AUC of 0.525 illustrating weak class separation capacity. Linear regression established a negative correlation between the SLE-key Rule-Out score and ACR SLE total scores. Spearman’s correlation was run to determine the relationship between ACR SLE total scores and SLE-key rule-out score and showed very weak negative correlation (rs = -0.0815, n = 155, p = 0.313). Conclusion  Our findings demonstrate that when applied in clinical practice in a rheumatology CTD clinic setting, the SLE-key® rule-out test does not accurately distinguish SLE from other CTDs. The development of a robust test that could achieve this would be pivotal. It is however important to highlight that the test was designed to distinguish healthy subjects from SLE patients and not for the purpose of differentiating SLE from other connective tissue diseases. Disclosure  S. Achieng: None. J.A. Reynolds: None. I.N. Bruce: Other; I.N.B is a National Institute for Health Research (NIHR) Senior Investigator and is funded by the NIHR Manchester Biomedical Research Centre. M. Bukhari: None.

scholarly journals The Relationship between Inflammation Markers (CRP, IL-6, sCD40L) and Colorectal Cancer Stage, Grade, Size and Location

Diagnostics ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 1382
Author(s):  
Olga Martyna Koper-Lenkiewicz ◽  
Violetta Dymicka-Piekarska ◽  
Anna Justyna Milewska ◽  
Justyna Zińczuk ◽  
Joanna Kamińska
Keyword(s):  
Colorectal Cancer ◽  
Linear Regression ◽  
Tumor Size ◽  
Distal Colon ◽  
Proximal Colon ◽  
Model Parameters ◽  
Grade Group ◽  
Who Grade ◽  
The Mean ◽  
Mean Concentration

The aim of the study was the evaluation whether in primary colorectal cancer (CRC) patients (n = 55): age, sex, TNM classification results, WHO grade, tumor location (proximal colon, distal colon, rectum), tumor size, platelet count (PLT), mean platelet volume (MPV), mean platelet component (MCP), levels of carcinoembryonic antigen (CEA), cancer antigen (CA 19-9), as well as soluble lectin adhesion molecules (L-, E-, and P-selectins) may influence circulating inflammatory biomarkers: IL-6, CRP, and sCD40L. We found that CRP concentration evaluation in routine clinical practice may have an advantage as a prognostic biomarker in CRC patients, as this protein the most comprehensively reflects clinicopathological features of the tumor. Univariate linear regression analysis revealed that in CRC patients: (1) with an increase in PLT by 10 × 103/μL, the mean concentration of CRP increases by 3.4%; (2) with an increase in CA 19-9 of 1 U/mL, the mean concentration of CRP increases by 0.7%; (3) with the WHO 2 grade, the mean CRP concentration increases 3.631 times relative to the WHO 1 grade group; (4) with the WHO 3 grade, the mean CRP concentration increases by 4.916 times relative to the WHO 1 grade group; (5) with metastases (T1-4N+M+) the mean CRP concentration increases 4.183 times compared to non-metastatic patients (T1-4N0M0); (6) with a tumor located in the proximal colon, the mean concentration of CRP increases 2.175 times compared to a tumor located in the distal colon; (7) in patients with tumor size > 3 cm, the CRP concentration is about 2 times higher than in patients with tumor size ≤ 3 cm. In the multivariate linear regression model, the variables that influence the mean CRP value in CRC patients included: WHO grade and tumor localization. R2 for the created model equals 0.50, which indicates that this model explains 50% of the variance in the dependent variable. In CRC subjects: (1) with the WHO 2 grade, the mean CRP concentration rises 3.924 times relative to the WHO 1 grade; (2) with the WHO 3 grade, the mean CRP concentration increases 4.721 times in relation to the WHO 1 grade; (3) with a tumor located in the rectum, the mean CRP concentration rises 2.139 times compared to a tumor located in the distal colon; (4) with a tumor located in the proximal colon, the mean concentration of CRP increases 1.998 times compared to the tumor located in the distal colon; if other model parameters are fixed.

scholarly journals 1412. The utility of respiratory viral panel testing for nosocomial fever in the neonatal intensive care unit

2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S713-S713
Author(s):  
Carlo Fopiano Palacios ◽  
Eric Lemmon ◽  
James Campbell
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Linear Regression ◽  
Length Of Stay ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
P Value ◽  
Fisher Exact Test ◽  
The Mean ◽  
Pcr Test

Abstract Background Patients in the neonatal intensive care unit (NICU) often develop fevers during their inpatient stay. Many neonates are empirically started on antibiotics due to their fragile clinical status. We sought to evaluate whether the respiratory viral panel (RVP) PCR test is associated with use of antibiotics in patients who develop a fever in the NICU. Methods We conducted a retrospective chart review on patients admitted to the Level 4 NICU of the University of Maryland Medical Center from November 2015 to June 2018. We included all neonates who developed a fever 48 hours into their admission. We collected demographic information and data on length of stay, fever work-up and diagnostics (including labs, cultures, RVP), and antibiotic use. Descriptive statistics, Fisher exact test, linear regression, and Welch’s ANOVA were performed. Results Among 347 fever episodes, the mean age of neonates was 72.8 ± 21.6 days, and 45.2% were female. Out of 30 total RVP samples analyzed, 2 were positive (6.7%). The most common causes of fever were post-procedural (5.7%), pneumonia (4.8%), urinary tract infection (3.5%), meningitis (2.6%), bacteremia (2.3%), or due to a viral infection (2.0%). Antibiotics were started in 208 patients (60%), while 61 neonates (17.6%) were already on antibiotics. The mean length of antibiotics was 7.5 ± 0.5 days. Neonates were more likely to get started on antibiotics if they had a negative RVP compared to those without a negative RVP (89% vs. 11%, p-value < 0.0001). Patients with a positive RVP had a decreased length of stay compared to those without a positive RVP (30.3 ± 8.7 vs. 96.8 ± 71.3, p-value 0.01). On multivariate linear regression, a positive RVP was not associated with length of stay. Conclusion Neonates with a negative respiratory viral PCR test were more likely to be started on antibiotics for fevers. Respiratory viral PCR testing can be used as a tool to promote antibiotic stewardship in the NICU. Disclosures All Authors: No reported disclosures

The impact of legs fat mass and legs lean fat mass on thigh circumference according cardiovascular risk: a population-based study

2021 ◽  
Vol 28 (Supplement_1) ◽  
Author(s):  
M Chlabicz ◽  
M Paniczko ◽  
J Jamolkowski ◽  
P Sowa ◽  
M Lapinska ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Regression Analysis ◽  
Linear Regression ◽  
Muscle Tissue ◽  
Fat Mass ◽  
Linear Regression Analysis ◽  
Population Based ◽  
Thigh Circumference ◽  
Tissue Model ◽  
The Mean

Abstract Funding Acknowledgements Type of funding sources: Public Institution(s). Main funding source(s): Medical University of Bialystok, Poland Introduction A low thigh circumference is associated with an increased risk of high blood pressure, diabetes, cardiovascular diseases, and total mortality. Objectives The aim of the study was to investigate the relationship between the thigh circumference and cardiovascular (CV) risk classes, and to assess what type of tissue, adipose tissue or muscle tissue affects the thigh circumference. Methods The longitudinal, population-based, Polish study was conducted in 2017-2020. A total of 931 individuals aged 20-79 were analyzed. Pol-SCORE system was used to assess the 10-year risk of fatal CV based on the following risk factors: age, gender, smoking, systolic blood pressure, and total cholesterol for individuals aged 40-70.  Then, CV risk classes were assessed using the 2019 ESC/EAS guidelines. The measurement of thigh circumference were performed directly below the gluteal fold of the thigh. Both thighs were measured and the mean value was calculated as the final thigh circumference. Body composition was assessed using Dual Energy X-ray Absorptiometry (DEXA). Results The mean age was 49.1 ± 15.5 years and 43.2% male. The mean thigh circumference was 58.2 ± 5.9 cm, the mean legs fat mass was 7.7 ± 2.8kg, and the mean legs lean mass was 16.9 ± 4.0kg. Lower thigh circumference was associated with higher CV risk classes in univariate linear regression analysis (β -0.516, p = 0.002), as well adjusted by age and sex (β -0.839, p = 0.008), adjusted by age, sex, BMI (β -0.886, p <0.001), and age, sex, WHR (β -0.988, p <0.001). In linear regression analysis legs adipose tissue and muscle tissue were related to the thigh circumference independently of CV risk classes (Model 1) and Pol-SCORE value (Model 2). However, fatty tissue (Model 1: β 0.746, p < 0.001; Model 2: β 0.749, p < 0.001) affects the thigh circumference more than the muscle tissue (Model 1: β 0.479, p < 0.001; Model 2: β 0.442, p < 0.001) (Fig. 1). Conclusion Smaller thigh circumference was associated with higher CV risk classes. Thigh circumference was more influenced by adipose tissue than by muscle tissue, regardless of the Pol-SCORE  or CV risk classes. Table 1. Variable Model 1 Model 2 Beta p R2 Beta p R2 Legs fat mass 0.746 <0.001 0.785 0.749 <0.001 0.760 Legs lean mass 0.479 <0.001 0.785 0.442 <0.001 0.760 Model 1: adjusted for Cardiovascular risk classesModel 2: adjusted for Pol-SCOREResults of the linear regression analysis thigh circumference in the general population Abstract Figure 1.

Lens and Peripheral Retinal Relationships During Vitrectomy: Comparison of 23-, 25-, and 27-Gauge Vitrectomy and Curved Endolaser Probes

2020 ◽  
pp. 247412642097197
Author(s):  
Jacob S. Duker ◽  
Michael J. Venincasa ◽  
Pedro F. Monsalve ◽  
Armando L. Garcia ◽  
Sander R. Dubovy ◽  
...  
Keyword(s):  
Insertion Site ◽  
Crystalline Lens ◽  
Peripheral Retina ◽  
Small Gauge ◽  
The Mean ◽  
Deceased Donors ◽  
23 Gauge ◽  
Considerable Range ◽  
Safe Access ◽  
Phakic Eyes

Purpose: This work aims to compare spatial relationships between the crystalline lens and vitrectomy instruments of different gauges. Methods: Eight phakic eyes recovered from deceased donors were used after fixation. Valved trocars (27-gauge, 25-gauge, and 23-gauge) were sequentially placed in the superotemporal quadrant 4 mm posterior to the limbus in each eye. Intraocular relationships of vitrectomy and curved endolaser probes were measured for each gauge. Results: There were no significant differences in maneuverability between instruments of different gauges. The mean distance from instrument to lens at the geometric center of the globe was 5.5 mm. Vitrectomy probes of all gauges could access the peripheral retina on both sides of the sclerotomy in the 3 to 4 o’clock position adjacent to the sclerotomy without touching the lens. The instruments could be advanced without lens touch to contact the retina within at least 2 mm of the ora serrata 180° away from the insertion site. Conclusions: Vitrectomy and curved endolaser probes achieved similar maneuverability relative to the lens regardless of gauge. This study confirms that small-gauge vitrectomy instruments have a considerable range of safe access to the peripheral retina in phakic eyes from a single sclerotomy.

scholarly journals Comparing plastic syringes and disposable columns to extract n-alkanes in forage and concentrate feeds

2010 ◽  
Vol 40 (8) ◽  
pp. 1844-1847 ◽  
Author(s):  
Dimas Estrasulas de Oliveira ◽  
Luis Orlindo Tedeschi
Keyword(s):  
Gas Chromatography ◽  
Linear Regression ◽  
Mean Square Error ◽  
Carbon Chain ◽  
Carbon Chain Length ◽  
Square Root ◽  
Mean Square ◽  
Alternative Material ◽  
The Mean ◽  
Disposable Plastic

Saturated aliphatic hydrocarbons (n-alkanes) were extracted from feed, orts, and bovine fecal samples using disposable, plastic 5mL-syringes as an alternative material to disposable columns, which are normally used in the liquid-solid extraction phase of n-alkanes. For both methods, the n-alkane extracts (carbon chain length between 31 and 36 atoms) were identified using gas chromatography. The linear regression between methods were: 1) feces: column Alkane=2.63+0.92×syringeAlkane [r²=0.94, square root of the mean square error (RMSE)=13.7mg kg-1, n=30] from which the intercept and the slope did not simultaneously differ from zero and unity (P>0.05), respectively; 2) feeds: column Alkane=0.36+1.12×syringeAlkane (r²=0.85, RMSE=1.9mg kg-1, n=21) from which the intercept and the slope did not simultaneously differ from zero and unity (P>0.05), respectively; 3) orts: column Alkane=0.49+0.92×syringeAlkane (r²=0.98, RMSE=1.2mg kg-1, n=15) from which the intercept and the slope did not simultaneously differ from zero and unity (P>0.05), respectively. Materials with low concentration of n-alkanes may affect the values obtained in both methods. These results suggested that disposable plastic syringes might be a viable alternative to columns thus, reducing analytical costs.

Life satisfaction and its relationship with spiritual well-being and religious practice in Iranian adolescent girls

2017 ◽  
Vol 31 (6) ◽  
Author(s):  
Fariba Alizadeh Sharajabad ◽  
Sakineh Mohammad-Alizadeh Charandabi ◽  
Mojgan Mirghafourvand
Keyword(s):  
Life Satisfaction ◽  
Linear Regression ◽  
Adolescent Girls ◽  
Well Being ◽  
Religious Practice ◽  
Multivariate Linear Regression ◽  
Multivariate Linear Regression Analysis ◽  
Income Status ◽  
Spiritual Well Being ◽  
The Mean

Abstract Introduction During recent years, special attention has been given to spiritual well-being and religious practice in the field of health. This study aimed to determine the predictors of life satisfaction among adolescent girls in Tabriz, Iran, 2015. Materials and methods This cross-sectional study was conducted on 520 female students studying in high schools who were selected using the cluster sampling method. Data collection was carried out through the questionnaires of socio-demographic characteristics, spiritual well-being (SWBS), religious practice (Arcury and colleagues) and life satisfaction (SWLS). Multivariate linear regression model was used for data analysis. Results The mean score of life satisfaction was 22.0 (SD: 6.0) from the attainable score of 5–35. The mean score (SD) of spiritual well-being was 90.2 (16.2), ranging from 20 to 120. The mean score of the religious practice was 32.1 (10.5) out of the achievable score range of 0–60. Multivariate linear regression analysis showed that existential well-being and sufficiency of income for expenses were predictors of life satisfaction and they explained 41.8% of the variance in the life satisfaction score. Conclusion The findings of the present study confirm the importance of existential well-being and a modifiable variable (sufficiency of income) in the life satisfaction. Thus, it is necessary to provide strategies to promote spirituality and improve the income status for improving adolescents’ life satisfaction.

scholarly journals EGG PRODUCTION CURVE OF RHODE ISLAND RED CHICKENS

2021 ◽  
Vol 28 (1) ◽  
pp. 78-83
Author(s):  
O. O. ONI ◽  
N. I. DIM ◽  
B. Y. ABUBAKAR ◽  
O. E. ASIRIBO
Keyword(s):  
Linear Regression ◽  
Mathematical Models ◽  
Rhode Island ◽  
Cycle Length ◽  
Egg Production ◽  
Goodness Of Fit ◽  
Production Data ◽  
Production Cycle ◽  
Breeder Hens ◽  
The Mean

Data on the monthly egg production of a strain of Rhode Island chickens (500 breeder hens) were used to test the goodness of fit of six mathematical models, viz; Exponential, Parabolic exponential, Wood's Gamma type and modified Gamma type by McNally, Inverse polynomial and Linear regression. Egg production was summarized for each hen into 28-d periods, starting from the day of firts egg. The hens were classified into different production cycle length based on the number of 28-d periods. The models were fitted to the mean results obtained for periods within groups of hens. The effect of cycle length on goodness of fit was also examined separately for the 'best' three models with highest R2 values. The egg production cycle (i.e. number of 28-d periods) varied from 9 to 15 periods. Similarly, the coefficients of determination (R2) varied from 0.16 to 0.95 from fitting the models to mean egg production data for groups of hens. The results suggest that thye 'best' three models that were chosen fitted 52 week laying records quite well, judging from their respective R2, which were higherf for McNally (0.95) and Parabolic exponential (0.93) than for wood (0.75). Based on the goodness of fit to 52-week production record, the McNally model gave the best results. However, its suitability in predicting full year production from part year record needs to be further investigated.

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