Kinetics of transepithelial movement of heavy metals in rat jejunum
1987 ◽
Vol 253
(2)
◽
pp. G134-G138
Keyword(s):
The kinetics of the transepithelial movement of heavy metals were studied in the perfused rat jejunum in situ. The peak appearance time (TET) of Zn, Ni, and Cd in portal venous blood was determined after their transient (10 s) introduction into the intestinal lumen. Observed TET values for these metals were positively correlated with their affinities for metallothionein and agreed with those predicted on the basis of a linear three-compartment model that does not allow for paracellular pathways. Further evidence was provided to support the hypothesis that Cd absorption consists first of Cd binding to negative membrane charges followed by a temperature-dependent internalization step.
1990 ◽
Vol 259
(3)
◽
pp. G443-G452
◽
Keyword(s):
2021 ◽
Vol 31
(1)
◽
pp. 20-30
1984 ◽
Vol 246
(1)
◽
pp. E14-E20
Keyword(s):
1989 ◽
Vol 47
◽
pp. 654-655
1995 ◽
Vol 53
◽
pp. 256-257
Keyword(s):
1987 ◽
Vol 45
◽
pp. 768-769
1986 ◽
Vol 44
◽
pp. 500-501
1993 ◽
Vol 51
◽
pp. 1172-1173