Dietary obesity in the mouse: interaction of strain with diet composition

1995 ◽  
Vol 268 (3) ◽  
pp. R658-R665 ◽  
Author(s):  
D. B. West ◽  
J. Waguespack ◽  
S. McCollister

The effect of varying dietary macronutrient content on the body composition of AKR/J and SWR/J mice was examined. Dietary fat was fed at three levels (45, 30, and 15 kcal%), while dietary protein also was varied across three levels (10, 20, and 30 kcal%). All mice were placed on the defined diets at 5 wk of age and maintained on these diets for 12 wk. AKR/J mice were significantly larger and had a significantly greater carcass fat content compared with SWR/J mice in all dietary conditions. There was a clear dose-response effect of dietary fat on body fat in the AKR/J mice. In contrast, SWR/J mice showed an increase of body fat only when fed the diet containing the highest level of dietary fat and the lowest protein concentration. High levels of dietary protein (30 kcal%) resulted in a significant decrease of carcass fat in the AKR/J mice compared with diets containing either 20 or 10 kcal% protein. This effect of protein was not observed in the SWR/J mice except in the groups fed the 45 kcal% fat diets. These findings demonstrate a strong interaction of genetic background and macronutrient content of the diet on body composition. The AKR/J strain of mouse has a greater percentage of carcass fat and is more responsive to the effects of dietary fat composition compared with the SWR/J strain.

2015 ◽  
Vol 3 (3) ◽  
pp. 256-262
Author(s):  
Rafia Bano ◽  
Eyad AlShammari ◽  
Aljawharah Almedan

Recent economic upliftment has brought many changes in the food choices and eating habits from home made to fast foods. This shift in the area of nutrition has given rise to overweight and obesity. Considering this the present study was planned to 1) determine the prevalence of overweight and obesity in a sample of university students 2) Find the relationship between the body composition and dietary fat and fibre intake. A total of 300 university females, 18-30+ years were randomly selected from all the colleges at the University of Hail for the present study. A Self-administered questionnaire was given, and the Body composition were measured with the help of bio-electric impedance analysis technique. Data were analysed using SPSS -17 software. The results indicated that 22% of the students were overweight and 21.3% were obese. The mean percent body fat as well as visceral fat exceeded its normal limits in around 44% of the participants. Vegetables and fruits, except dates, were not frequently consumed by most of the participants with a mean intake of fibre as 14g/day. Significant positive correlations were found among Body Mass Index (BMI), Body Fat% and Visceral Fat level. Strong positive correlation was also found between BMI and fat intake (P< 0.01), whereas the body composition and fiber intake was found to be inversely correlated (P<0.01). Findings of present study suggest that there is need for coordinated efforts at all levels to reduce the prevalence of obesity and high percentage of body fat, and to develop healthy eating habits in young generation.


2003 ◽  
Vol 23 (2_suppl) ◽  
pp. 55-57 ◽  
Author(s):  
Vincent C. Chow ◽  
Chi-wai Lee ◽  
Eva H. Ho ◽  
Ching-kit Chan ◽  
Rose M. Yong ◽  
...  

Objective The Dialysis Outcomes Quality Initiative (DOQI) guidelines suggest that anthropometric measurements are useful in assessment of nutrition. However, the technique is operator-dependent and time consuming. To estimate fat-free mass and fat mass, bioelectrical impedance analysis (BIA) measures the impedance of an electrical current passing through the body. Our aim in the present study was to validate the use of BIA in continuous ambulatory peritoneal dialysis (CAPD) patients. Design We recruited patients from the CAPD clinic. The biceps, triceps, subscapular, and suprailiac skinfold thickness were measured by Harpenden skinfold calipers (British Indicators, Burgess Hill, West Sussex, U.K.). Using a linear regression equation (Durin and Womersley) and the Siri equation, we calculated percentage body fat composition from the anthropometric measurements. For BIA assessment, fat composition was measured using the Body Composition Analyzer (TBF-300GS: Tanita Corporation of America, Arlington Heights, IL, U.S.A.). Results We recruited a total of 60 patients who had been on CAPD for 21.8 ± 23 months. The percentage of body fat in the study group as estimated by anthropometry was 27.5% ± 8.6% (range: 5.78% – 40.4%). By BIA, the percentage of body fat was 17.6% ± 8.9% (range: 2.4% – 42.3%). The results by the two methods were highly correlated ( r = 0.712, p < 0.001). By paired t-test, the mean difference in body fat composition using the two different methods was 9.9% ± 6.6% ( p < 0.001). Conclusions Measurement of body fat composition in CAPD patients by BIA and by anthropometry were highly correlated. The body fat composition measured by BIA was lower than that measured by anthropometry. The BIA method is simple and noninvasive. It may play a role in monitoring trend of body composition in CAPD patients in an outpatient setting.


2019 ◽  
Vol 31 (3) ◽  
pp. 212-218

Both insulin and leptin are major contributors for the body energy balance. Obesity is a state of energy imbalance and is also associated with changes in both insulin sensitivity and leptin sensitivity. The aim of this study was to find out the relationship between insulin sensitivity and body fat composition, and leptin sensitivity in non-obese and obese adults. A total of 86 adults participated: 42 non-obese and 44 over-weight/obese. Body fat (BF) percent was determined by skinfold method. Fasting plasma glucose was analyzed by glucose oxidase-phenol and 4 aminophenazone (GOD-PAP) method using spectro-photometer, fasting serum insulin and leptin concentrations by direct sandwich ELISA method and resting energy expenditure (REE) by indirect calorimetry. Leptin sensitivity index and insulin sensitivity were expressed as REE : Leptin ratio and homeostatic model assessment-insulin resistance (HOMA-IR), respectively. It was found that median value of HOMA-IR was significantly higher [2.93 vs 1.72, p<0.01] and leptin sensitivity was significantly lower [116.76 vs 265.66, p<0.001] in the overweight/obese adults than the non-obese adults, indicating that insulin sensitivity and leptin sensitivity were markedly reduced in overweight/obese adults in compare to non-obese adults. There was a moderate degree of positive relationship between HOMA-IR and BF only in the overweight/obese (ρ=0.509, n=44, p<0.001) and all adults (ρ=0.39, n=86, p<0.001). Similarly, a weak negative relationship between leptin sensitivity index and HOMA-IR was found in the overweight/obese (ρ=-0.328, n=44, p<0.05) and all adults (ρ=-0.35, n=86, p<0.01). It can be concluded that the insulin sensitivity was adiposity dependent, but, it did not depend on leptin sensitivity.


Sports ◽  
2018 ◽  
Vol 6 (3) ◽  
pp. 85 ◽  
Author(s):  
Jennifer Fields ◽  
Justin Merrigan ◽  
Jason White ◽  
Margaret Jones

The purpose of this study was to assess the body composition of male and female basketball athletes (n = 323) across season, year, and sport-position using air displacement plethysmography. An independent sample t-test assessed sport-position differences. An analysis of variance was used to assess within-subjects across season (pre-season, in-season, and off-season), and academic year (freshman, sophomore, and junior). For both men and women basketball (MBB, WBB) athletes, guards had the lowest body fat, fat mass, fat free mass, and body mass. No seasonal differences were observed in MBB, but following in-season play for WBB, a reduction of (p = 0.03) in fat free mass (FFM) was observed. Across years, MBB showed an increase in FFM from freshman to sophomore year, yet remained unchanged through junior year. For WBB across years, no differences occurred for body mass (BM), body fat (BF%), and fat mass (FM), yet FFM increased from sophomore to junior year (p = 0.009). Sport-position differences exist in MBB and WBB: Guards were found to be smaller and leaner than forwards. Due to the importance of body composition (BC) on athletic performance, along with seasonal and longitudinal shifts in BC, strength and conditioning practitioners should periodically assess athletes BC to ensure preservation of FFM. Training and nutrition programming can then be adjusted in response to changes in BC.


2002 ◽  
Vol 45 (6) ◽  
pp. 535-545
Author(s):  
A. D. Mitchell ◽  
A. Scholz ◽  
V. Pursel

Abstract. The purpose of this study was to evaluate the use of a cross-sectional scan as an alternative to the total body DXA scan for predicting the body composition of pigs in vivo. A total of 212 pigs (56 to 138 kg live body weight) were scanned by DXA. The DXA scans were analyzed for percentage fat and lean in the total body and in 14 cross-sections (57.6 mm wide): 5 in the front leg/thoracic region, 4 in the abdominal region, and 5 in the back leg region. Regression analysis was used to compare total body and cross-sectional DXA results and chemical analysis of total body fat, protein and water. The relation (R2) between the percentage fat in individual slices and the percentage of total body fat measured by DXA ranged from 0.78 to 0.97 and by chemical analysis from 0.71 to 0.85, respectively. The relation between the percentage of lean in the individual slices and chemical analysis for percentage of total body protein and water ranged from 0.48 to 0.60 and 0.56 to 0.76, respectively. These results indicate that total body composition of the pig can be predicted (accurately) by performing a time-saving single-pass cross-sectional scan.


2009 ◽  
Vol 18 (2) ◽  
pp. 38 ◽  
Author(s):  
J Durandt ◽  
S Du Toit ◽  
J Borresen ◽  
T Hew-Butler ◽  
H Masimla ◽  
...  

Objective. The aim of this study was to describe the body composition, strength and speed characteristics of elite junior South African rugby players. Design. Cross-sectional. Setting. Field study. Subjects. Rugby players (16 and 18 years old, N = 174) selected for the South African Rugby Union National Green Squad. Outcome measures. Body composition, 10 m and 40 m speed, agility, 1RM bench press, underhand pull-ups, push-ups, multistage shuttle run. Results. The under-16 players were on average shorter (175.6 ± 5.7 v. 179.2 ± 6.7 cm), weighed less (76.5 ± 8.2 v. 84.8 ± 8.3 kg) had less upper body absolute strength (77.1 ± 11.8 kg v. 95.3 ± 16.7 kg) and muscular endurance (41 ± 12 v. 52 ± 15 push-ups) and aerobic fitness (87.1 ± 19.4 v. 93.5 ± 15.3 shuttles) than the under-18 players. There were no differences in body fat, sprinting speed (10 m and 40 m) or agility between the two age groups. There were differences between playing positions, with the props having the most body fat, strongest upper bodies, slowest sprinting speed, least agility and lowest aerobic capacity compared with players in the other positions. Conclusion. This study provides data for elite junior rugby players and can be used to monitor the progression of players after intervention while also assisting with talent identification for the different playing positions. South African Journal of Sports Medicine Vol. 18 (2) 2006: pp. 38-45


2018 ◽  
Vol 28 (3) ◽  
pp. 279-283 ◽  
Author(s):  
Christopher Rosimus

The body composition of a squash player may affect athletic performance as carrying excessive body fat may increase injury risk and impair agility and speed. This case study outlines the effect of a nutritional intervention on body composition, vitamin D status, and physical performance of a female squash player. A structured, 6-week, moderate energy–restricted diet (70–78% of estimated energy requirement of 2,300 kcal) was implemented with weekly support. A daily supplement of vitamin D, omega-3 fatty acids, and a multivitamin and whey protein was used. Full blood count, vitamin D status, body composition, and physical performance assessments were carried out at baseline and Week 6 of intervention. Body composition changes were measured using the BOD POD™ and skinfold calipers. Body fat was 23% at baseline and 22% at Week 6. Mean sum of eight skinfolds was 127.4 ± 2.2 mm at baseline and 107.3 ± 0.4 mm at Week 6. Lean body mass-to-fat mass ratio improved from 3.4 at baseline to 3.7 at Week 6. The greatest increments compared with baseline in serum markers were 25-hydroxyvitamin D3 (68%), ferritin (31%), eosinophils (20%), and triglycerides (16%). All physical performance measures improved, with reactive strength index (4.8%), and on-court repeated speed (6.0%) showing the greatest improvements from baseline. This intervention demonstrates that structured energy restriction alongside appropriately structured strength and conditioning training is an effective way to gradually reduce the body fat and improve the body composition of a female athlete.


2005 ◽  
Vol 69 (12) ◽  
pp. 2409-2415 ◽  
Author(s):  
Asuka AKAHOSHI ◽  
Kazunori KOBA ◽  
Rie ENMOTO ◽  
Kazuko NISHIMURA ◽  
Yukiko HONDA ◽  
...  

2019 ◽  
Vol 15 (1) ◽  
pp. 108-116 ◽  
Author(s):  
Silvia Miteva ◽  
Iliya Yanev ◽  
Stefan Kolimechkov ◽  
Lubomir Petrov ◽  
Lubomir Mladenov ◽  
...  

Rhythmic gymnastics is a sport in which special consideration is given to diet and body appearance. The purpose of this study was to assess the nutrient intake and body composition of elite rhythmic gymnasts in comparison with guidelines for female gymnasts. Twenty-one elite rhythmic gymnasts from Bulgaria were divided into three groups: First National Team, mean age 24.2; Second National Team, mean age 17.8; and Junior National Team, mean age 12.6. Body fat and muscle mass were estimated by skinfold methods, and a food frequency questionnaire was applied to assess the nutrient intake. The gymnasts showed low per cent of body fat (13.9% for the First National Team, 17.0% for the Second National Team, and 15.6% for the Junior National Team) and high per cent muscle mass (44.0, 40.5, and 37.6%, respectively). They kept their weight close to the ideal one, as recommended by the coaches, and the following equation best corresponded to the recommended ideal weight: height (cm) − 118. The energy intake was lower than the calculated energy requirements, in addition to low intake of fat and carbohydrates. The relative protein intake was 1.7 g/kg for the First National Team, 1.7 g/kg for the Second National Team, and 1.9 g/kg for Junior National Team, and the energy contribution of proteins was higher than the recommended 15%. Rhythmic gymnasts should be encouraged to maintain their ideal weight without great variance from the health-related guidelines, and coaches should consider not only the body image, but also the norms relating to body composition in women when determining ideal weight.


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