Parasitic Helminths: New Weapons against Immunological Disorders
2010 ◽
Vol 2010
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pp. 1-9
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Keyword(s):
The prevalence of allergic and autoimmune diseases is increasing in developed countries, possibly due to reduced exposure to microorganisms in childhood (hygiene hypothesis). Epidemiological and experimental evidence in support of this hypothesis is accumulating. In this context, parasitic helminths are now important candidates for antiallergic/anti-inflammatory agents. Here we summarize antiallergic/anti-inflammatory effects of helminths together along with our own study of the effects ofSchistosoma mansonion Th17-dependent experimental arthritis. We also discuss possible mechanisms of helminth-induced suppression according to the recent advances of immunology.
2020 ◽
Vol 21
(4)
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pp. 1219
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2019 ◽
Vol Volume 12
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pp. 709-719
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2013 ◽
Vol 13
(1)
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pp. 70-86
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