scholarly journals Microbiological and Pharmacological Evaluation of the MicropropagatedRubus liebmanniiMedicinal Plant

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Adelina Jiménez-Arellanes ◽  
Jorge Cornejo-Garrido ◽  
Gabriela Rojas-Bribiesca ◽  
María del Pilar Nicasio-Torres ◽  
Salvador Said-Fernández ◽  
...  
Keyword(s):  
Chemical Composition ◽  
Endemic Species ◽  
Giardia Lamblia ◽  
Biological Effects ◽  
Ethanolic Extract ◽  
Gastrointestinal Diseases ◽  
Gastrointestinal Disorders ◽  
Aerial Parts ◽  
Micropropagated Plant

Rubus liebmanniiis an endemic species from Mexico used in traditional medicine primarily to treat dysentery and cough. Thein vitroactivity againstGiardia lambliaandEntamoeba histolyticathat produces the ethanolic extract of the aerial parts of the plant led us to expand the pharmacological and phytochemical research of this species. Gastrointestinal disorders including amebiasis remain one of the health problems that need to be addressed and it is of interest to find alternatives that improve their treatment. Also, it is important to emphasize thatR. liebmanniigrows wild in the country and is not found in abundance; therefore, alternatives that avoid overexploitation of the natural resource are mandatory. Ongoing with the evaluation of the potentialities thatR. liebmanniipossesses for treating infectious gastrointestinal diseases, the aim of the present study was to evaluate the biological effects and the chemical composition of the micropropagated plant.

Chemical composition of the essential oils from the aerial parts of two Malagasy endemic species (Apiaceae): Billburttia capensoides Sales & Hedge and Billburttia vaginoides Sales & Hedge

2018 ◽  
Vol 33 (8) ◽  
pp. 1200-1203
Author(s):  
Stephan R. Rakotonandrasana ◽  
Delphin J. R. Rabehaja ◽  
Mathieu Paoli ◽  
Dominique de Rocca Serra ◽  
Charles Andrianjara ◽  
...  
Keyword(s):  
Chemical Composition ◽  
Essential Oils ◽  
Endemic Species ◽  
Aerial Parts

scholarly journals An Ethanolic Extract of Boehmeria caudata Aerial Parts Displays Anti-inflammatory and Anti-tumor Activities

2020 ◽  
Vol 7 (01) ◽  
pp. e17-e25 ◽  
Author(s):  
Paula Pereira de Paiva ◽  
Fabiana Regina Nonato ◽  
Ana Lúcia Tasca Gois Ruiz ◽  
Ilza Maria de Oliveira Sousa ◽  
Rafael Rosolen Teixeira Zafred ◽  
...  
Keyword(s):  
Anticancer Agents ◽  
Ethanolic Extract ◽  
Experimental Models ◽  
New Drugs ◽  
Antiproliferative Effects ◽  
Aerial Parts ◽  
Anti Inflammatory ◽  
Inflammatory Action ◽  
Effective Source

AbstractThe tumor microenvironment presents several therapeutic targets, with inflammation being one of them. In search of new drugs, plants have shown to be an effective source of potent anti-inflammatory and anticancer agents. This study aimed to evaluate the antitumoral and inflammatory activities of Boehmeria caudata aerial parts extract. Bioguided in vitro antiproliferative screening showed that phenanthroquinolizidine obtained from the aerial B. caudata ethanolic extract had a straight relationship with activity. Moreover, the orally administered ethanolic extract reduced Ehrlich solid tumor growth and displayed an anti-inflammatory effect in both evaluated experimental models (carrageenan-induced paw edema and croton oil-induced ear edema). These results suggest that the antitumor activity of the ethanolic extract could be explained by antiproliferative effects associated with anti-inflammatory action.

scholarly journals Chemical Composition and Biological Activity of the Essential Oil from Jamaican Cleome serrata

2012 ◽  
Vol 7 (9) ◽  
pp. 1934578X1200700 ◽  
Author(s):  
Megil J. McNeil ◽  
Roy B. R. Porter ◽  
Lawrence A. D. Williams
Keyword(s):  
Chemical Composition ◽  
Essential Oil ◽  
Antimicrobial Activities ◽  
Diffusion Method ◽  
Oil Composition ◽  
Filter Paper Disc ◽  
Aerial Parts ◽  
Main Components ◽  
Total Oil

The chemical composition of the essential oil obtained from the aerial parts of Cleome serrata by hydrodistillation was analyzed by employing GC-FID, GC-MS and RI. Fourteen compounds comprising 90.4% of the total oil composition were characterized. The main components identified were ( Z)-phytol (53.0%) and di(2-ethylhexyl)-phthalate (DEHP) (14.7%). The oil was evaluated for its in vitro antimicrobial activities against nine pathogenic microorganisms using the filter paper disc diffusion method. Moderate antimicrobial activity was observed against five of the pathogens assayed. In addition, the essential oil was tested against the sweet potato weevil, Cylas formicarius elegantulus. Strong knockdown insecticidal activity was observed.

scholarly journals Prosopis Plant Chemical Composition and Pharmacological Attributes: Targeting Clinical Studies from Preclinical Evidence

Biomolecules ◽  
2019 ◽  
Vol 9 (12) ◽  
pp. 777 ◽  
Author(s):  
Javad Sharifi-Rad ◽  
Farzad Kobarfard ◽  
Athar Ata ◽  
Seyed Abdulmajid Ayatollahi ◽  
Nafiseh Khosravi-Dehaghi ◽  
...  
Keyword(s):  
Chemical Composition ◽  
Clinical Studies ◽  
Positive Impact ◽  
Biological Effects ◽  
Food Supplement ◽  
In Vivo Studies ◽  
Plant Chemical ◽  
Food Applications

Members of the Prosopis genus are native to America, Africa and Asia, and have long been used in traditional medicine. The Prosopis species most commonly used for medicinal purposes are P. africana, P. alba, P. cineraria, P. farcta, P. glandulosa, P. juliflora, P. nigra, P. ruscifolia and P. spicigera, which are highly effective in asthma, birth/postpartum pains, callouses, conjunctivitis, diabetes, diarrhea, expectorant, fever, flu, lactation, liver infection, malaria, otitis, pains, pediculosis, rheumatism, scabies, skin inflammations, spasm, stomach ache, bladder and pancreas stone removal. Flour, syrup, and beverages from Prosopis pods have also been potentially used for foods and food supplement formulation in many regions of the world. In addition, various in vitro and in vivo studies have revealed interesting antiplasmodial, antipyretic, anti-inflammatory, antimicrobial, anticancer, antidiabetic and wound healing effects. The phytochemical composition of Prosopis plants, namely their content of C-glycosyl flavones (such as schaftoside, isoschaftoside, vicenin II, vitexin and isovitexin) has been increasingly correlated with the observed biological effects. Thus, given the literature reports, Prosopis plants have positive impact on the human diet and general health. In this sense, the present review provides an in-depth overview of the literature data regarding Prosopis plants’ chemical composition, pharmacological and food applications, covering from pre-clinical data to upcoming clinical studies.

Seasonal variations in chemical composition and in vitro biological effects of fine PM from Milan

Chemosphere ◽  
2010 ◽  
Vol 78 (11) ◽  
pp. 1368-1377 ◽  
Author(s):  
Maria Grazia Perrone ◽  
Maurizio Gualtieri ◽  
Luca Ferrero ◽  
Claudia Lo Porto ◽  
Roberto Udisti ◽  
...  
Keyword(s):  
Chemical Composition ◽  
Seasonal Variations ◽  
Biological Effects

scholarly journals In vitro Antimicrobial Properties and Chemical Composition of Santolina chamaecyparissus Essential Oil from Algeria

2012 ◽  
Vol 7 (7) ◽  
pp. 1934578X1200700 ◽  
Author(s):  
Samah Djeddi ◽  
Khadidja Djebile ◽  
Ghania Hadjbourega ◽  
Zoubida Achour ◽  
Catherine Argyropoulou ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Candida Albicans ◽  
Chemical Composition ◽  
Essential Oil ◽  
Antimicrobial Properties ◽  
Klebsiella Pneumonia ◽  
Aerial Parts

The chemical composition of the essential oil obtained from the aerial parts of Santolina chamaecyparissus L., growing in Algeria, was investigated by GC-MS analyses. A total of 36 compounds were identified, accounting for 91.7% of the essential oil obtained. Camphor (31.1%) and cubenol (17.0%) were the predominant compounds. The potential of the antimicrobial activity was also investigated and the tested sample proved to be very active against Klebsiella pneumonia and Candida albicans (34.1 ± 0.02 mm and 35.0 ± 0.01 mm, respectively). Transverse sections of the leaf and stem of the plant suggest that the essential oil is localized in endogenous and exogenous sites.

scholarly journals Comparison of the Chemical Composition of Valeriana parviflora Essential Oils Collected in the Venezuelan Andes in two Different Seasons

2015 ◽  
Vol 10 (4) ◽  
pp. 1934578X1501000
Author(s):  
Sammy Fernández ◽  
María Rondón ◽  
Janne Rojas ◽  
Antonio Morales ◽  
Luis Rojas-Fermin
Keyword(s):  
Chemical Composition ◽  
Essential Oil ◽  
Essential Oils ◽  
Endemic Species ◽  
Rainy Season ◽  
Climatic Conditions ◽  
Isovaleric Acid ◽  
Aerial Parts ◽  
Different Seasons ◽  
Main Components

The essential oils obtained by hydrodistillation of the aerial parts of Valeriana parviflora (Trevir) BM Vadillo, an endemic species of the Venezuelan Andes, collected from the same location in two different seasons (dry and rainy) of the year, were analyzed by GC/MS. The essential oil obtained during the dry season showed linalool (11.9%), eugenol (8.9%), p-menth-1-en-9-al (8.7%) and α-terpineol (7.7%) as main components, while the oil obtained from the rainy season collection showed o-xylol (16.2%), 3-methyl isovaleric acid (10.6%) and geranial (9.5%) as major compounds. Some of the differences in the composition of these oils might be due to the climatic conditions at the time of harvesting.

Chemical Composition and in vitro Antimicrobial Activity of the Essential Oils of Two Helichrysum Species from Tanzania

2004 ◽  
Vol 59 (5-6) ◽  
pp. 368-372 ◽  
Author(s):  
Christos Bougatsos ◽  
Olipa Ngassapa ◽  
Deborah K. B. Runyoro ◽  
Ioanna B. Chinou
Keyword(s):  
Antimicrobial Activity ◽  
Chemical Composition ◽  
Essential Oils ◽  
Pathogenic Fungi ◽  
Caryophyllene Oxide ◽  
In Vitro Antimicrobial Activity ◽  
Aerial Parts ◽  
Main Components

The chemical composition of the essential oils obtained from the aerial parts of Helichrysum cymosum and H. fulgidum, from Tanzania, were analyzed by GC and GC/MS. A total of sixty-five compounds, representing 92.4% and 88.2% of the two oils, respectively, were identified. trans-Caryophyllene, caryophyllene oxide, β-pinene, p-cymene, spathulenol and β- bourbonene were found to be the main components. Furthermore, the oils were tested against six gram (±) bacteria and three pathogenic fungi. It was found that the oil of H. fulgidum exhibited significant antimicrobial activity, while the oil of H. cymosum was not active at all.

scholarly journals Adverse biological effects of Milan urban PM looking for suitable molecular markers of exposure

2012 ◽  
Vol 18 (4-2) ◽  
pp. 635-641 ◽  
Author(s):  
Paride Mantecca ◽  
Maurizio Gualtieri ◽  
Eleonora Longhin ◽  
Giuseppina Bestetti ◽  
Paola Palestini ◽  
...  
Keyword(s):  
Molecular Markers ◽  
Chemical Composition ◽  
Biological Effects ◽  
Detailed Knowledge ◽  
Biological Responses ◽  
Physico Chemical ◽  
Biological Hazard ◽  
The Impact

The results presented summarise the ones obtained in the coordinated research project Tosca, which extensively analysed the impact of Milan urban PM on human health. The molecular markers of exposure and effects of seasonally and size-fractionated PMs (summer and winter PM10, PM2.5) were investigated in in vitro (human lung cell lines) and in vivo (mice) systems. The results obtained by the analyses of cytotoxic, pro-inflammatory and genotoxic parameters demonstrate that the biological responses are strongly dependent upon the PM samples seasonal and dimensional variability, that ultimately reflect their chemical composition and source. In fact summer PM10, enriched in crustal elements and endotoxins, was the most cytotoxic and pro-inflammatory fraction, while fine winter PMs induced genotoxic effects and xenobiotic metabolizing enzymes (like CYP1B1) production, likely as a consequence of the higher content in combustion derived particles reach in PAHs and heavy toxic metals. These outcomes outline the need of a detailed knowledge of the PMs physico-chemical composition on a local scale, coupled with the biological hazard directly associated to PM exposure. Apparently this is the only way allowing scientists and police-makers to establish the proper relationships between the respirable PM quantity/quality and the health outcomes described by clinicians and epidemiologists.

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