scholarly journals Fiber Generators in Needleless Electrospinning

2012 ◽  
Vol 2012 ◽  
pp. 1-13 ◽  
Author(s):  
Haitao Niu ◽  
Tong Lin
Keyword(s):  
Production Rate ◽  
Scale Up ◽  
Electrospun Nanofibers ◽  
Scaling Up ◽  
Electrospinning Process ◽  
Recent Advances ◽  
Needleless Electrospinning ◽  
Application Potential

The conventional electrospinning often uses a needle-like nozzle to produce nanofibers with a very low production rate. Despite the enormous application potential, needle electrospun nanofibers meet difficulties in broad applications in practice, due to the lack of an economic and efficient way to scale up the electrospinning process. Recently, needleless electrospinning has emerged as a new electrospinning mode and shown ability to produce nanofibers on large-scales. It has been established that the fiber generator, also referred to as “spinneret” in this paper, in needleless electrospinning plays a key role in scaling up the nanofiber production. This paper summarizes the recent advances in the development of needleless spinnerets and their influences on electrospinning process, nanofiber quality, and productivity.

Optimization of meta-aramid electrospun nanofibers productivity through wire-based electrospinning setup scale up

2016 ◽  
Vol 48 (1) ◽  
pp. 236-254
Author(s):  
Oertel Aurélie ◽  
Khenoussi Nabyl ◽  
Schacher Laurence ◽  
Adolphe Dominique C ◽  
Graftieaux Hélène
Keyword(s):  
Fiber Diameter ◽  
Scale Up ◽  
Electrospun Nanofibers ◽  
Substrate Material ◽  
Electrospinning Process ◽  
Influential Factors ◽  
Morphological Properties ◽  
The Past ◽  
Electrode Wire ◽  
Nonwoven Mats

Electrospinning process has been widely used over the past decades for manufacturing nanofibers. The control of the electrospinning parameters is crucial to obtain nanofibers (nonwoven mats) with optimized morphological properties. The aim of this study is to precisely define the electrospinnability of a meta-aramid solution through wire-based electrospinning setup processing. Experiments have been conducted following a design of experiment to study the influence of each parameter. Individual effects and/or combined interactions on obtained fiber diameter and general morphology (mean fiber distribution and nonfibrous area) have been investigated. The five studied process parameters are: applied voltage, relative humidity, temperature, distance between spinning electrode wire and substrate material, and airflow going through the spinning chamber. Each parameter was varied at three levels. Significant effects of parameters have been observed. The obtained results have allowed us to determine the influential factors and reduce the domain study.

A Method for Scale-Up of Grooved Nanofibers via Flat Off-Centered Core-Shell Structure Spinneret

2014 ◽  
Vol 989-994 ◽  
pp. 556-559 ◽  
Author(s):  
Hui Hui Wu ◽  
Xiao Hua Meng ◽  
Yong Chun Zeng
Keyword(s):  
Production Rate ◽  
Shell Structure ◽  
Flat Surface ◽  
Scale Up ◽  
Electrospinning Process ◽  
Core Shell ◽  
Core Needle ◽  
The Core ◽  
Core Shell Structure ◽  
Novel Design

An approach to the scale-up of grooved nanofibers via a flat off-centered core-shell structure spinneret has been developed in this study. The spinneret with a flat surface involves shell-holes and off-centered core-needles. The position of the core-needle in the hole and the electrospinning process do influence the formation and structure of the grooved nanofibers. The production rate of the core-shell nanofibers can be enhanced by increasing the hole and needle number of the spinneret. This novel design is expected to provide a promising method towards the massive production of grooved nanofibers.

Fundamental Study on Needleless Electrospinning Based on Metal (Card) Clothing

2013 ◽  
Vol 662 ◽  
pp. 103-107
Author(s):  
Yan Bo Liu ◽  
Ze Ru Zhang ◽  
Peng Cheng Li ◽  
Velmurugan Thavasi
Keyword(s):  
Theoretical Analysis ◽  
Polyvinyl Alcohol ◽  
Scaling Up ◽  
Electrospinning Process ◽  
Experimental Results ◽  
Fundamental Study ◽  
Needleless Electrospinning ◽  
Electrospinning Method ◽  
New Process ◽  
Different Types

This paper discloses a method for producing nanofibers by a needleless electrospinning process based on the metal (card) clothing. 20% w/w polyvinyl alcohol (PVA) solution was employed to demonstrate the feasibility of this new electrospinning technology. Different types of metal clothing were used to produce PVA nanofibers under different voltages in the experiments; theoretical analysis of this new electrospinning method was also carried out to understand the experimental results. The results indicated the great potential for scaling up this new avenue for producing nanofibers through electrospinning, especially when medium sized clothing was used in the new process.

Effect of Solution Properties and Operating Parameters on Needleless Electrospinning of Poly(Ethylene Oxide) Nanofibers Loaded with Bovine Serum Albumin

2019 ◽  
Vol 16 (10) ◽  
pp. 913-922 ◽  
Author(s):  
Ramprasath Ramakrishnan ◽  
Jolius Gimbun ◽  
Praveen Ramakrishnan ◽  
Balu Ranganathan ◽  
Samala Murali Mohan Reddy ◽  
...  
Keyword(s):  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Bovine Serum ◽  
Salt Content ◽  
Electrospinning Process ◽  
Solution Viscosity ◽  
Operating Parameters ◽  
Solution Properties ◽  
Wire Electrode ◽  
Needleless Electrospinning

Background: This paper presents the effect of solution properties and operating parameters of polyethylene oxide (PEO) based nanofiber using a wire electrode-based needleless electrospinning. Methods: The feed solution was prepared using a PEO dissolved in water or a water-ethanol mixture. The PEO solution is blended with Bovine Serum Albumin protein (BSA) as a model drug to study the effect of the electrospinning process on the stability of the loaded protein. The polymer solution properties such as viscosity, surface tension, and conductivity were controlled by adjusting the solvent and salt content. The morphology and fiber size distribution of the nanofiber was analyzed using scanning electron microscopy. Results: The results show that the issue of a beaded nanofiber can be eliminated either by increasing the solution viscosity or by the addition of salt and ethanol to the PEO-water system. The addition of salt and solvent produced a high frequency of smaller fiber diameter ranging from 100 to 150 nm. The encapsulation of BSA in PEO nanofiber was characterized by three different spectroscopy techniques (i.e. circular dichroism, Fourier transform infrared, and fluorescence) and the results showed the BSA is well encapsulated in the PEO matrix with no changes in the protein structure. Conclusion: This work may serve as a useful guide for a drug delivery industry to process a nanofiber at a large and continuous scale with a blend of drugs in nanofiber using a wire electrode electrospinning.

scholarly journals Strategies for involving patients and the public in scaling-up initiatives in health and social services: protocol for a scoping review and Delphi survey

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Ali Ben Charif ◽  
◽  
Karine V. Plourde ◽  
Sabrina Guay-Bélanger ◽  
Hervé Tchala Vignon Zomahoun ◽  
...  
Keyword(s):  
Social Services ◽  
Scoping Review ◽  
Delphi Study ◽  
Public Involvement ◽  
Scale Up ◽  
Scaling Up ◽  
Delphi Survey ◽  
The Public ◽  
Health And Social Services ◽  
Scoping Reviews

Abstract Background The scale-up of evidence-based innovations is required to reduce waste and inequities in health and social services (HSS). However, it often tends to be a top-down process initiated by policy makers, and the values of the intended beneficiaries are forgotten. Involving multiple stakeholders including patients and the public in the scaling-up process is thus essential but highly complex. We propose to identify relevant strategies for meaningfully and equitably involving patients and the public in the science and practice of scaling up in HSS. Methods We will adapt our overall method from the RAND/UCLA Appropriateness Method. Following this, we will perform a two-prong study design (knowledge synthesis and Delphi study) grounded in an integrated knowledge translation approach. This approach involves extensive participation of a network of stakeholders interested in patient and public involvement (PPI) in scaling up and a multidisciplinary steering committee. We will conduct a systematic scoping review following the methodology recommended in the Joanna Briggs Institute Reviewers Manual. We will use the following eligibility criteria: (1) participants—any stakeholder involved in creating or testing a strategy for PPI; (2) intervention—any PPI strategy proposed for scaling-up initiatives; (3) comparator—no restriction; (4) outcomes: any process or outcome metrics related to PPI; and (5) setting—HSS. We will search electronic databases (e.g., Medline, Web of Science, Sociological Abstract) from inception onwards, hand search relevant websites, screen the reference lists of included records, and consult experts in the field. Two reviewers will independently select and extract eligible studies. We will summarize data quantitatively and qualitatively and report results using the PRISMA extension for Scoping Reviews (PRISMA-ScR) checklist. We will conduct an online Delphi survey to achieve consensus on the relevant strategies for PPI in scaling-up initiatives in HSS. Participants will include stakeholders from low-, middle-, and high-income countries. We anticipate that three rounds will allow an acceptable degree of agreement on research priorities. Discussion Our findings will advance understanding of how to meaningfully and equitably involve patients and the public in scaling-up initiatives for sustainable HSS. Systematic review registration We registered this protocol with the Open Science Framework on August 19, 2020 (https://osf.io/zqpx7/).

scholarly journals Promoting Scale-Up Across a Global Project Platform: Lessons from the Evidence to Action Project

2021 ◽  
Author(s):  
Laura Ghiron ◽  
Eric Ramirez-Ferrero ◽  
Rita Badiani ◽  
Regina Benevides ◽  
Alexis Ntabona ◽  
...  
Keyword(s):  
Family Planning ◽  
Scale Up ◽  
Scaling Up ◽  
Sub Saharan Africa ◽  
Health System Strengthening ◽  
Country Level ◽  
Look Ahead ◽  
Republic Of The Congo ◽  
Sub Saharan ◽  
Multi Stakeholder

AbstractThe USAID-funded flagship family planning service delivery project named Evidence to Action (E2A) worked from 2011 to 2021 to improve family planning and reproductive health for women and girls across seventeen nations in sub-Saharan Africa using a “scaling-up mindset.” The paper discusses three key lessons emerging from the project’s experience with applying ExpandNet’s systematic approach to scale up. The methodology uses ExpandNet/WHO’s scaling-up framework and guidance tools to design and implement pilot or demonstration projects in ways that look ahead to their future scale-up; develop a scaling-up strategy with local stakeholders; and then strategically manage the scaling-up process. The paper describes how a scaling-up mindset was engendered, first within the project’s technical team in Washington and then how they subsequently sought to build capacity at the country level to support scale-up work throughout E2A’s portfolio of activities. The project worked with local multi-stakeholder resource teams, often led by government officials, to equip them to lead the scale-up of family planning and health system strengthening interventions. Examples from project experience in the Democratic Republic of the Congo, Kenya, Nigeria, and Uganda illustrating key concepts are discussed. E2A also established a community of practice on systematic approaches to scale up as a platform for sharing learning across a variety of technical agencies engaged in scale-up work and to create learning opportunities for interacting with thought leaders around critical scale-up issues.

scholarly journals Recent Advances in the BiVO4 Photocatalyst for Sun-Driven Water Oxidation: Top-Performing Photoanodes and Scale-Up Challenges

Catalysts ◽  
2017 ◽  
Vol 7 (12) ◽  
pp. 13 ◽  
Author(s):  
Kristine Tolod ◽  
Simelys Hernández ◽  
Nunzio Russo
Keyword(s):  
Water Oxidation ◽  
Scale Up ◽  
Recent Advances

scholarly journals Citizen workshops in public libraries to disseminate and discuss primary care research results: a scaling-up study

2020 ◽  
Author(s):  
José Massougbodji ◽  
Hervé Tchala Vignon Zomahoun ◽  
Evehouenou Lionel Adisso ◽  
Jasmine Sawadogo ◽  
Valérie Borde ◽  
...  
Keyword(s):  
Knowledge Translation ◽  
Financial Incentives ◽  
General Public ◽  
Large Scale ◽  
Public Libraries ◽  
Scale Up ◽  
Scaling Up ◽  
Computer Assisted ◽  
Knowledge Gain ◽  
Research Results

Abstract Background Little is known about engaging patients and stakeholders in the process of scaling up effective knowledge translation interventions targeting the general public. Using an integrated knowledge translation approach, we aimed to scale up and evaluate an effective pilot program of disseminating research results in public libraries. Methods We conducted a scaling-up study targeting the general public. Based on our successful pilot project, we co-developed and implemented a larger-scale program of free citizen workshops in public libraries, this time in close research partnership with stakeholders and patient representatives. Citizen workshops, each facilitated by one participating physician and one science communicator, consisted of a 45-min computer-assisted presentation and a 45-min open exchange. Additional scale-up costs included offering financial incentives to stakeholders involved and the purchase of audio-visual equipment. The intervention outcome was knowledge gained. Scale-up outcomes were satisfaction, appropriateness, coverage, time and costs. An evaluation questionnaire was used to collect data of interest. Both quantitative and qualitative analyses were performed. Results The workshop theme chosen by patient and stakeholder representatives was the high prevalence of medication overuse among people over 65 years of age. From April to May 2019, 26 workshops were given in 25 public libraries reaching 362 people. Eighteen participating physicians and six science communicators facilitated the workshops. Participants reported significant knowledge gain (mean difference 2.1, 95% CI 2.0–2.2, P < .001). Median score for overall public satisfaction was 9/10 (IQR 8–10). A high level of appropriateness of the workshops was globally rated by the public participants Coverage was 92.6% of the total number of public libraries targeted. Costs were $6,051.84 CAD for workshop design and $22,935.41 CAD for scaling them up. Conclusion This project successfully established a large-scale and successful KT bridge between researchers, clinicians, and citizens via public libraries. This study provides a model for a dissemination practice that benefits the general public by both engaging them in the dissemination process and by targeting them directly.

What does it Take to Scale up and Sustain Evidence-Based Practices?

2013 ◽  
Vol 79 (2) ◽  
pp. 195-211 ◽  
Author(s):  
Janette K. Klingner ◽  
Alison G. Boardman ◽  
Kristen L. Mcmaster
Keyword(s):  
Research Policy ◽  
Scale Up ◽  
Scaling Up ◽  
District Leadership ◽  
Small Scale ◽  
Evidence Based ◽  
Policy And Practice ◽  
Evidence Based Practices ◽  
Strategic Reading ◽  
Collaborative Strategic Reading

This article discusses the strategic scaling up of evidence-based practices. The authors draw from the scholarly work of fellow special education researchers and from the field of learning sciences. The article defines scaling up as the process by which researchers or educators initially implement interventions on a small scale, validate them, and then implement them more widely in real-world conditions. Examples of scale-up research are included. The authors discuss challenges to scaling up and sustaining evidence-based practices, followed by factors that can potentially support scaling up, including professional development and district leadership. A case example describes how these issues can play out by highlighting experiences with a Collaborative Strategic Reading (CSR) scale-up research project in a large urban school district. The article concludes by offering recommendations for research, policy, and practice.

Sign in / Sign up

Export Citation Format

Share Document