scholarly journals Markers of Sleep-Disordered Breathing and Prediabetes in US Adults

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Omayma Alshaarawy ◽  
Srinivas Teppala ◽  
Anoop Shankar
Keyword(s):  
Mexican Americans ◽  
Odds Ratio ◽  
Sleep Disordered Breathing ◽  
Positive Association ◽  
Nutrition Examination Survey ◽  
Health And Nutrition ◽  
Increased Risk ◽  
Subgroup Analyses ◽  
The Relationship ◽  
Disordered Breathing

Background. Prediabetes is a preclinical stage in the hyperglycemia continuum where subjects are at increased risk of developing diabetes. Several studies reported a positive association between markers of sleep-disordered breathing (SDB) and diabetes. However, few studies investigated the relationship between SDB markers and prediabetes.Methods. We examined 5,685 participants ≥20 years from the National Health and Nutrition Examination Survey (NHANES) 2005–2008. The exposure of interest was SDB markers including sleep duration, snoring, snorting, and daytime sleepiness. The outcome was prediabetes (n=2058), among subjects free of diabetes.Results. SDB markers were associated with prediabetes. Compared to those without any sleep disturbance, the multivariable odds ratio (OR) (95% confidence interval (CI)) of prediabetes among those with three or more SDB markers was 1.69 (1.28–2.22). In subgroup analyses, the association between SDB markers and prediabetes was stronger among women (OR (95% CI) = 2.09 (1.36–3.23) when compared to men (1.52 (1.00–2.35)) and was present among non-Hispanic whites (2.66 (1.92–3.69)) and Mexican Americans (1.99 (1.13–3.48)), but not among non-Hispanic blacks (1.10 (0.70–1.73)).Conclusion. SDB markers were associated with prediabetes. This association was stronger in women and was present mainly in non-Hispanic whites and Mexican Americans.

scholarly journals Markers of Sleep Disordered Breathing and Diabetes Mellitus in a Multiethnic Sample of US Adults: Results from the National Health and Nutrition Examination Survey (2005–2008)

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Charumathi Sabanayagam ◽  
Srinivas Teppala ◽  
Anoop Shankar
Keyword(s):  
Ethnic Differences ◽  
National Health ◽  
Sleep Disturbances ◽  
Sleep Disordered Breathing ◽  
Summary Score ◽  
Nutrition Examination Survey ◽  
Health And Nutrition ◽  
Nationally Representative ◽  
Multiethnic Sample ◽  
Disordered Breathing

We examined gender and ethnic differences in the association between sleep disordered breathing (SDB) and diabetes among 6,522 participants aged ≥20 years from the National Health and Nutrition Examination Survey 2005–08. SDB severity was defined based on an additive summary score including sleep duration, snoring, snorting, and daytime sleepiness. We found that the summary SDB score was significantly associated with diabetes after adjusting for potential confounders in the whole population. Compared to those without any sleep disturbance, the multivariable odds ratio (OR) (95% confidence interval (CI)) of diabetes among those with ≥3 sleep disturbances was 2.04 (1.46–2.87). In sex-specific analyses, this association was significant only in women (OR (95% CI) = 3.68 (2.01–6.72)) but not in men (1.10 (0.59–2.04)),P-interaction=0.01. However, there were no ethnic differences in this association,P-interaction=0.7. In a nationally representative sample of US adults, SDB was independently associated with diabetes only in women, but not in men.

scholarly journals Sleep Disordered Breathing and Depression among U.S. Adults: National Health and Nutrition Examination Survey, 2005-2008

SLEEP ◽  
2012 ◽  
Vol 35 (4) ◽  
pp. 461-467 ◽  
Author(s):  
Anne G. Wheaton ◽  
Geraldine S. Perry ◽  
Daniel P. Chapman ◽  
Janet B. Croft
Keyword(s):  
National Health ◽  
Sleep Disordered Breathing ◽  
Nutrition Examination Survey ◽  
Health And Nutrition ◽  
Disordered Breathing

scholarly journals Association between Serum Liver Enzymes and Metabolic Syndrome in Korean Adults

2018 ◽  
Vol 15 (8) ◽  
pp. 1658 ◽  
Author(s):  
Hae Kim ◽  
Mi Han
Keyword(s):  
Metabolic Syndrome ◽  
Odds Ratio ◽  
Adjusted Odds Ratio ◽  
Liver Enzymes ◽  
Nutrition Examination Survey ◽  
Normal Range ◽  
Health And Nutrition ◽  
Increased Risk ◽  
Quartile Group ◽  
Normal Alt

The purpose of this study was to evaluate the association between alanine aminotransferase (ALT) and aspartate aminotransferase (AST), and metabolic syndrome (MS) in the Korean population. A total of 11,587 adults ≥30 years of age and with complete data were selected from Korea National Health and Nutrition Examination Survey VI conducted from 2013 to 2015. Normal ALT and AST levels were divided into quartiles, and their associations with MS were assessed by logistic regression analysis. Elevated levels of ALT [adjusted odds ratio (aOR) = 7.90, 95% confidence interval (CI) = 6.50–9.60] and AST (aOR = 3.81, 95% CI = 3.10–4.74) were both significantly associated with a higher prevalence of MS. The quartile group containing the highest levels of ALT and AST within the normal range also showed an increased risk of MS and its components. Elevated levels of ALT and AST, even within the normal range, were associated with prevalence of MS.

scholarly journals The Relationship between Sleep-Disordered Breathing and Hypertension in a Nationally Representative Sample

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Sarah Dee Geiger ◽  
Anoop Shankar
Keyword(s):  
Representative Sample ◽  
Sleep Disordered Breathing ◽  
Positive Association ◽  
Cross Sectional Study ◽  
Summary Score ◽  
Cross Sectional ◽  
Health And Nutrition ◽  
Race Ethnicity ◽  
Nationally Representative ◽  
Disordered Breathing

Sleep-disordered breathing (SDB), characterized by abnormal respiratory patterns or inadequate quantity of ventilation, is common in adults. A positive association between SDB and hypertension has been established, in both cross-sectional and longitudinal studies. One void in the literature concerns the role of race/ethnicity in the association between SDB and hypertension. In this context, a cross-sectional study was performed on 6,783 participants in the National Health and Nutrition Examination Survey 2005–2008. Participants were ≥age 20 and free from cardiovascular disease. The outcome of interest was hypertension, defined as ≥140 mmHg systolic blood pressure (BP), and/or ≥90 mmHg diastolic BP or antihypertensive medication use. Self-reported SDB was positively associated with hypertension, independent of confounders such as depression, diabetes, cholesterol levels, and body mass index, among others. The association persisted in subgroup analyses by gender, with a stronger association among males than females, as well as by race/ethnicity, with non-Hispanic blacks displaying the strongest association. In the multivariable-adjusted model, compared to a sleep summary score of zero (referent), the OR (95% CI) of hypertension for non-Hispanic blacks was 1.34 (0.98–1.83) for a sleep summary score of 1, 1.44 (1.06–1.97) for a score of 2 and 3.72 (1.98–7.00) for a score of >3;p-trend< 0.0001. SDB was positively associated with hypertension in a large, nationally representative sample of US adults. Along with being prevalent, SDB is also treatable. Therefore, our results are important for minority race/ethnic groups who typically experience a higher baseline for negative health outcomes.

scholarly journals The Association between BMI and Osteoarthritis in Adults

2021 ◽  
Author(s):  
Zheling Liu ◽  
Liwen Zheng ◽  
Liguang Xu
Keyword(s):  
Mexican Americans ◽  
Positive Relationship ◽  
Regression Analyses ◽  
Multivariate Logistic Regression ◽  
Men And Women ◽  
Health And Nutrition ◽  
Subgroup Analyses ◽  
Prevalence Of Obesity ◽  
Race Ethnicity ◽  
The Relationship

Abstract Objectives: The prevalence of obesity-related symptomatic OA has been found to increase. We investigated the relationship between BMI and osteoarthritis in 14,058 20-85 year-old participants from the National Health and Nutrition Examination Survey (NHANES). Methods: To estimate the association between BMI and osteoarthritis, multivariate logistic regression analyses were conducted. Fitted smoothing curves. Results: After adjusting for other confounding factors, we found that BMI was positively correlated with osteoarthritis. On subgroup analyses, stratified by sex and race/ethnicity, the positive correlation between BMI and Osteoarthritis in men and women, as well as in whites, blacks, and Mexican Americans, still exists. Conclusions: Our study revealed a positive relationship between BMI and Osteoarthritis in most adults.

scholarly journals Markers of Sleep-Disordered Breathing and Metabolic Syndrome in a Multiethnic Sample of US Adults: Results from the National Health and Nutrition Examination Survey 2005–2008

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Charumathi Sabanayagam ◽  
Ruoxin Zhang ◽  
Anoop Shankar
Keyword(s):  
Metabolic Syndrome ◽  
Sleep Duration ◽  
National Health ◽  
Daytime Sleepiness ◽  
Sleep Disturbances ◽  
Sleep Disordered Breathing ◽  
Nutrition Examination Survey ◽  
Short Sleep Duration ◽  
Health And Nutrition ◽  
Disordered Breathing

Previous studies have documented an association between markers of sleep-disordered breathing (SDB) and metabolic syndrome. However, it is not clear if there are gender or ethnic differences in this association. We examined 6,122 participants aged ≥20 years from the National Health and Nutrition Examination Survey 2005–08. Metabolic syndrome was defined as the presence of ≥3 of the following components: (1) abdominal obesity, (2) elevated blood triglycerides, (3) low HDL cholesterol, (4) high BP, and (5) hyperglycemia. SDB severity was defined based on an additive summary score including sleep duration, snoring, snorting, and daytime sleepiness. We found that short sleep duration, snoring, snorting, daytime sleepiness and the summary SDB score were significantly associated with metabolic syndrome independent of potential confounders. Compared to those without any sleep disturbance, the multivariable odds ratio (OR) (95% confidence interval [CI]) of metabolic syndrome among those with three or more sleep disturbances was 3.92 (2.98–5.16). In subgroup analyses, this association was consistently present among men and women and all race-ethnic groups. In summary, SDB was independently associated with metabolic syndrome in a nationally representative sample of US adults.

Sleep Characteristics and Hearing Loss in Older Adults: The National Health and Nutrition Examination Survey 2005–2006

2021 ◽  
Author(s):  
Kening Jiang ◽  
Adam P Spira ◽  
Nicholas S Reed ◽  
Frank R Lin ◽  
Jennifer A Deal
Keyword(s):  
Older Adults ◽  
Hearing Loss ◽  
Sleep Duration ◽  
High Frequency ◽  
Pure Tone ◽  
Sleep Disordered Breathing ◽  
Nutrition Examination Survey ◽  
Cross Sectional ◽  
Health And Nutrition ◽  
Disordered Breathing

Abstract Background Sleep characteristics might be associated with hearing loss through disturbed energy metabolism and disrupted cochlear blood flow, but prior evidence is limited. This study aims to investigate cross-sectional associations of sleep duration and signs/symptoms of sleep-disordered breathing with hearing in a nationally representative cohort of U.S. older adults aged 70 and over. Methods We studied 632 older adults aged 70+ years from the 2005-2006 cycle of National Health and Nutrition Examination Survey (NHANES). Hearing thresholds were measured using pure-tone audiometry and were averaged to create speech-frequency (0.5-4 kHz), low-frequency (0.5-2 kHz) and high-frequency (4-8 kHz) pure-tone averages (PTAs) in better-hearing ear, with higher values indicate worse hearing. Sleep duration and signs/symptoms of sleep-disordered breathing (snoring, snorting/stopping breathing, excessive sleepiness) were collected through questionnaire. Multivariable-adjusted spline models with knots at 6 and 8 hours were fitted for associations between sleep duration and PTAs. Multivariable-adjusted linear regression was used for associations between sleep-disordered breathing and PTAs. Primary models adjusted for demographic and lifestyle factors, secondary models additionally adjusted for cardiovascular factors. Results When sleep duration exceeded 8 hours, every additional hour of sleep duration was marginally associated with higher(poorer) high-frequency PTA (Primary:2.45 dB HL, 95% CI:-0.34, 5.24; Secondary:2.89 dB HL, 95% CI:0.02, 5.76). No associations were observed between sleep-disordered breathing and hearing. Conclusions Longer sleep duration is marginally associated with poorer high-frequency hearing among older adults sleeping more than 8 hours. However, we cannot infer temporality given the cross-sectional design. Future longitudinal studies are needed to establish temporality and clarify mechanisms.

scholarly journals Sleep Outcomes in Children with Single-Suture Craniosynostosis Compared with Unaffected Controls

2017 ◽  
Vol 54 (6) ◽  
pp. 734-738
Author(s):  
Baiyang Sun ◽  
Yona K. Cloonan ◽  
Brent R. Collett ◽  
Matthew L. Speltz
Keyword(s):  
Outcome Measures ◽  
Odds Ratio ◽  
Sleep Disordered Breathing ◽  
Adjusted Odds Ratio ◽  
Sleep Problems ◽  
Standardized Assessments ◽  
Increased Risk ◽  
Single Suture ◽  
Disordered Breathing

Objective To compare risk for sleep-disordered breathing between children with and without single-suture craniosynostosis. Participants A total of 184 children with single-suture craniosynostosis and 184 controls. Main Outcome Measures Parent reported sleep-disordered breathing-related symptoms. Results Current sleep problems were reported in 19% of patients with single-suture craniosynostosis and 14% of controls (adjusted odds ratio = 1.6; 95% CI, 0.9 to 2.8). Ever having sleep problems was reported in 25% and 23% of cases and controls, respectively (adjusted odds ratio = 1.2; 95% CI, 0.7 to 1.9). Overall, snoring was statistically associated with single-suture craniosynostosis ( P = .01) and was more often reported as 2+ nights per week (versus never) in patients with single-suture craniosynostosis (13%) than in controls (4%) (adjusted odds ratio = 3.5; 95% CI, 1.5 to 8.2). Conclusions Though preliminary, increased presence of snoring during sleep in children with single-suture craniosynostosis compared with controls suggests that children with isolated single-suture craniosynostosis may be at increased risk for sleep-disordered breathing. Further study using standardized assessments of sleep-disordered breathing is needed.

scholarly journals Association between age-related cataract and blepharoptosis in Korean adults: a population-based study

2022 ◽  
Vol 12 (1) ◽  
Author(s):  
Kyung-Sun Na ◽  
Su-Kyung Jung ◽  
Younhea Jung ◽  
Kyungdo Han ◽  
Jiyoung Lee ◽  
...  
Keyword(s):  
Risk Factors ◽  
Odds Ratio ◽  
Positive Association ◽  
Population Based ◽  
Nutrition Examination Survey ◽  
Population Based Study ◽  
Health And Nutrition ◽  
Age Related ◽  
Adjusted Logistic Regression ◽  
Similar Risk

AbstractCataract and blepharoptosis are both commonly encountered ophthalmic problems in older adults. Since they share similar risk factors, it is plausible that there may be an association between the two conditions. We examined data from the Korean National Health and Nutrition Examination Survey (KNHANES) 2010–2012 to determine if there is an association between age-related cataract and blepharoptosis. Multivariable adjusted logistic regression analysis was conducted to examine the odds ratio (OR) and 95% confidence interval (CI) for association of each specific type of cataract with presence of blepharoptosis. Of the 10,387 eligible participants, 4782 (46.0%) had cataract and 1419 (15.8%) had blepharoptosis. There were more participants with blepharoptosis in the cataract group, compared with those in the no cataract group. After adjusting for potential confounders, participants with blepharoptosis had a higher risk of total cataract (OR: 1.557, 95% CI 1.201–2.019) and nuclear subtype cataract (OR: 1.305, 95% CI 1.050–1.620). Blepharoptosis was associated with significantly higher odds of cataract in obese participants when compared with non-obese participants (p for interaction = 0.0236). Our study revealed a positive association between age-related cataract and blepharoptosis; it suggests that thorough ophthalmic assessment is needed when assessing patients who are planning cataract or blepharoptosis surgery.

Association between Dietary Inflammatory Index and kidney stones in US adults: Data from the NHANES 2007-2016

2021 ◽  
pp. 1-27
Author(s):  
Chichen Zhang ◽  
Shi Qiu ◽  
Haiyang Bian ◽  
Bowen Tian ◽  
Haoyuan Wang ◽  
...  
Keyword(s):  
National Health ◽  
Kidney Stones ◽  
Primary Outcome ◽  
Secondary Outcome ◽  
Nutrition Examination Survey ◽  
Dietary Inflammatory Index ◽  
Inflammatory Index ◽  
Health And Nutrition ◽  
Multivariate Adjustment ◽  
Increased Risk

Abstract Objective: We evaluate the association between the Dietary Inflammatory Index (DII) and kidney stones. Design: We performed a cross-sectional analysis using data from National Health and Nutrition Examination Survey. Dietary intake information was assessed using first 24-HR dietary recall interviews, and the Kidney Conditions was presented by questionnaire. The primary outcome was to investigate the association between DII and incidence of kidney stones, and the secondary outcome was to assess the association between DII and nephrolithiasis recurrence. Setting: The National Health and Nutrition Examination Survey (NHANES), 2007-2016. Participants: The study included 25984 NHANES participants, whose data on DII and kidney stones were available, of whom 2439 reported a history of kidney stones. Results: For the primary outcome, after fully multivariate adjustment, DII score is positively associated with the risk of kidney stones (OR = 1.07; 95% CI: [1.04–1.10]). Then, compared Q4 with Q1, a significant 38% increased likelihood of nephrolithiasis was observed. (OR=1.38; 95% CI: [1.19–1.60]). For the secondary outcome, the multivariate regression analysis showed that DII score is positively correlated with nephrolithiasis recurrence (OR=1.07; 95% CI: [1.00–1.15]). The results noted that higher DII scores (Q3 and Q4) are positively associated with a significant 48% and 61% increased risk of nephrolithiasis recurrence compared with the reference after fully multivariate adjustment. (OR=1.48; 95% CI: [1.07–2.05]; OR=1.61; 95% CI: [1.12–2.31]). Conclusions: Our findings revealed that increased intake of pro-inflammatory diet, as a higher DII score, is correlated with increased odds of kidney stones incidence and recurrence.

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