scholarly journals The Association between BMI and Osteoarthritis in Adults

Author(s):  
Zheling Liu ◽  
Liwen Zheng ◽  
Liguang Xu

Abstract Objectives: The prevalence of obesity-related symptomatic OA has been found to increase. We investigated the relationship between BMI and osteoarthritis in 14,058 20-85 year-old participants from the National Health and Nutrition Examination Survey (NHANES). Methods: To estimate the association between BMI and osteoarthritis, multivariate logistic regression analyses were conducted. Fitted smoothing curves. Results: After adjusting for other confounding factors, we found that BMI was positively correlated with osteoarthritis. On subgroup analyses, stratified by sex and race/ethnicity, the positive correlation between BMI and Osteoarthritis in men and women, as well as in whites, blacks, and Mexican Americans, still exists. Conclusions: Our study revealed a positive relationship between BMI and Osteoarthritis in most adults.

Diseases ◽  
2020 ◽  
Vol 8 (2) ◽  
pp. 10
Author(s):  
Azad R. Bhuiyan ◽  
Nusrat Kabir ◽  
Amal K. Mitra ◽  
Oluwabunmi Ogungbe ◽  
Marinelle Payton

Hepatitis B virus (HBV) infection is the most common form of viral hepatitis and remains a global public health problem, even though the HBV vaccine is available. HBV leads to chronic liver disease, including cirrhosis, liver cancer, and death. This study aimed to identify disparities in HBV vaccine coverage with the serological test by race/ethnicity, adjusting for gender and age. In this study, 5735 adult participants were included, obtaining data from the National Health and Nutrition Examination Survey (NHANES), 2015–2016. Proc survey frequency, bivariate- and multivariate logistic regression in the weighted sample were performed due to the complex survey design of NHANES. Data were analyzed using SAS, version 9.2.4. The overall prevalence of HBV vaccine coverage was only 23.3% (95% CI: 20.7%, 25.9%). In a multivariate logistic regression model, data showed that Mexican Americans (OR 0.57, 95% CI: 0.38, 0.86) and African Americans (OR 0.70, 95% CI 0.56, 0.84) had lower vaccine coverage compared to Whites. Females had (OR 1.55, 95% CI: 1.30, 1.85) higher vaccine coverage compared to men. Older age groups (30–49 years) (OR 0.41, 95% CI: 0.32, 0.52) and age group ≥ 50 years (OR 0.18, 95% CI 0.14, 0.23) had lower vaccine coverage compared to younger adults aged 18–29 years.


2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Yeonghee Eun ◽  
Kyung-Do Han ◽  
Da Hye Kim ◽  
In Young Kim ◽  
Eun-Jung Park ◽  
...  

AbstractHyperuricemia and anemia share several comorbidities, but the association between the two conditions remains unclear. The purpose of this study was to investigate the association between hyperuricemia and anemia. Data of 10794 subjects from the Korean National Health and Nutrition Examination Survey conducted in 2016–2017 were analyzed using multivariate logistic regression analyses. An association between anemia and hyperuricemia was not evident in subjects without chronic kidney disease (CKD). In patients with CKD, anemia increased the risk of hyperuricemia by 2-fold. This association remained significant when adjusting for the glomerular filtration rate. In subgroup analyses, the association of anemia with hyperuricemia was significant in subjects aged ≥65 years, and in those with diabetes or hypertension. Subgroup analyses of CKD patients showed similar results. In the current study using data from Korean representative samples, anemia in subjects with CKD was associated with a 2-fold increase in the risk of hyperuricemia, which remained significant even after adjustment for renal function.


2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Omayma Alshaarawy ◽  
Srinivas Teppala ◽  
Anoop Shankar

Background. Prediabetes is a preclinical stage in the hyperglycemia continuum where subjects are at increased risk of developing diabetes. Several studies reported a positive association between markers of sleep-disordered breathing (SDB) and diabetes. However, few studies investigated the relationship between SDB markers and prediabetes.Methods. We examined 5,685 participants ≥20 years from the National Health and Nutrition Examination Survey (NHANES) 2005–2008. The exposure of interest was SDB markers including sleep duration, snoring, snorting, and daytime sleepiness. The outcome was prediabetes (n=2058), among subjects free of diabetes.Results. SDB markers were associated with prediabetes. Compared to those without any sleep disturbance, the multivariable odds ratio (OR) (95% confidence interval (CI)) of prediabetes among those with three or more SDB markers was 1.69 (1.28–2.22). In subgroup analyses, the association between SDB markers and prediabetes was stronger among women (OR (95% CI) = 2.09 (1.36–3.23) when compared to men (1.52 (1.00–2.35)) and was present among non-Hispanic whites (2.66 (1.92–3.69)) and Mexican Americans (1.99 (1.13–3.48)), but not among non-Hispanic blacks (1.10 (0.70–1.73)).Conclusion. SDB markers were associated with prediabetes. This association was stronger in women and was present mainly in non-Hispanic whites and Mexican Americans.


2021 ◽  
Author(s):  
Zilong Zhang ◽  
Kun Jin ◽  
Shi Qiu ◽  
Xinyi Huang ◽  
Dan Hu ◽  
...  

Abstract Background: It have been reported that polycyclic aromatic hydrocarbons (PAHs) were associated with a variety of diseases, but it is still unclear that whether PAHs are associated with urinary incontinence (UI). This study aims to assess the association between PAHs and UI.Methods: Data were collected from the National Health and Nutrition Examination Survey (NHANES) from 2007 to 2016. 10 PAHs were detected totally. UI was diagnosed and distinguished into stress UI (SUI), urgency UI (UUI), and mixed UI (MUI) by answers of self-reported questions. Multivariate logistic regression analyses categorizing PAHs as quartiles were performed to detect the correlation between urinary PAHs and all three UI subtypes. Models were adjusted for common epidemiological factors including demographic and living habits factors.Results: A total of 12,393 participants of NHANES with available urine PAHs and UI data were eligible. No significant differences were observed between characteristics of participants with and without UI. Increasing prevalence of UUI was associated with the highest quantiles of 1-hydroxynapthalene (OR=1.208, 95%CI=1.026-1.422, p for trend=0.036), 1-hydroxyphenanthrene (OR=1.203, 95%CI=1.017-1.423, p for trend=0.004), and 1-hydroxypyrene (OR=1.251, 95%CI=1.062-1.475, p for trend=0.013) compared with the lowest quantiles. Increasing rate of SUI was observed in participants with higher exposure of all 9 PAHs (p for trend<0.025) except 3-hydroxyfluorene (OR=1.115, 95%CI=0.929-1.338, p for trend=0.241). Compared with the lowest quantiles, association between MUI and the highest quantiles of 1-hydroxyphenanthrene (OR=1.554, 95%CI=1.244-1.942, p for trend<0.001) and 1-hydroxypyrene (OR=1.307, 95%CI=1.047-1.630, p for trend=0.018) was observed.Conclusion: Our study suggested a positive relationship between U-PAHs and the prevalence of all three types of UI. Almost all PAHs are positively correlated with SUI.


2019 ◽  
Vol 8 (3) ◽  
pp. 365 ◽  
Author(s):  
Catherine Andersen ◽  
Terrence Vance

Dyslipidemias and leukocytosis are associated with cardiovascular disease and immune disorders. Mechanistic studies have shown lipoprotein metabolism to play a significant role in the regulation of atherosclerosis development and leukocyte activation, whereas lipid-lowering treatments have been shown to exert beneficial anti-inflammatory and immunomodulatory effects in clinical trials. However, the relationship between clinical markers of lipid metabolism and leukocyte counts has not been extensively evaluated at the population level. We aimed to determine whether clinical blood lipid measures are associated with leukocyte counts in the general U.S. population represented in the National Health and Nutrition Examination Survey (NHANES) 1999–2004, and whether differences exist between men and women (n = 5647). We observed a strong positive linear trend between serum triglycerides vs. blood lymphocyte and basophil counts in both men and women, whereas a positive trend between monocytes vs. triglycerides and lymphocytes vs. total cholesterol and LDL-cholesterol (LDL-C) was only detected in women. Conversely, HDL-C was inversely associated with a greater number of leukocyte subsets in men, whereas inverse trends between HDL-C vs. lymphocytes were observed in both men and women. In multiple regression models, a 10% increase in total cholesterol, LDL-C, and triglycerides was associated with a predicted 1.6%, 0.6%, and 1.4% increase in blood lymphocyte counts in women, respectively, whereas no relationship was observed in men. In both men and women, a 10% increase in triglycerides was additionally associated with higher lymphocyte, neutrophil, and basophil counts, whereas 10% increases in HDL-cholesterol were associated with significantly lower lymphocyte, neutrophil, eosinophil, and basophil counts in men, in addition to lower lymphocyte and monocyte counts in women. These findings suggest that clinical lipid markers may be used to predict blood leukocyte distributions, and that a gender-specific relationship exists between distinct classes of serum lipids and immune cell subsets.


2018 ◽  
Vol 126 (2) ◽  
pp. 241-252 ◽  
Author(s):  
Jenny Meggs ◽  
Mark A. Chen ◽  
Stefan Koehn

This study examined the relationship between mental toughness (MT), subjectively perceived performance, and dispositional flow in a sample of 114 high-performing ironmen and standard distance triathletes ( Mage = 28.81 years, SD = 3.45) recruited from triathlon clubs. Participants completed the Mental Toughness Questionnaire, Dispositional Flow Scale, and self-rated subjectively perceived performance. Pearson’s correlations between these measures revealed a significant, positive relationship between global MT and subjective performance ratings ( r = .62, p < .01) and between global MT and all Dispositional Flow subscales ( r = .67–.81, p < .05). Linear regression analyses found that MT subscales accounted for 64% of the variance in dispositional flow. Subjective performance ratings did not add significantly to the regression model. Overall, these findings suggest that MT may contribute positively to ironman competitors’ and triathletes’ exertion of the cognitive and emotional control necessary to experience flow and perform better. We discuss these results in the context of ironman and triathlon competitions.


2011 ◽  
Vol 1 (2) ◽  
pp. 292-325 ◽  
Author(s):  
Özen Odağ

This contribution focuses on three reader characteristics that potentially influence the ways in which men and women become engaged during reading: a reader’s gender, empathy and ability to critically and constructively perceive reality. These traits (in addition to biological sex) were assessed as part of an experimental reading study, and subsequently used to predict the variation in engagement during reading. Eighty-eight readers (50% female) took part in the study and read one of four narratives randomly assigned to them. Reader traits and reading engagement were assessed by questionnaire. Regression analyses showed that the relationship between biological sex and reading engagement is considerably more complex than mostly assumed: contrary to expectation, gender did not impact reading engagement in significant ways. In line with the hypothesis, however, higher levels of empathy, of critical thinking about mediated contents, and of constructively adopting narrative contents to one’s own life, significantly related to higher degrees of the reading engagement of men and women. Biological sex turned out to be significant for reading engagement only in combination with the other reader traits.


2018 ◽  
Vol 25 (1) ◽  
pp. 3-13 ◽  
Author(s):  
Scott D. Landes ◽  
Andrew S. London

Objective: Informed by a social determinants of health framework, we investigate the relationship between self-reported ADHD diagnosis status and adult health, and whether observed associations are attenuated by biomedical and socioeconomic factors. Method: Using 2007 National Health Interview Survey data ( N = 19,104), we present multivariate logistic regression analyses of associations between self-reported ADHD diagnosis status and five adult health outcomes. Results: ADHD diagnosis was significantly associated with higher odds of injury, physical health conditions, functional limitations, fair/poor health, and psychological distress in fully specified models (adjusted odds ratios [AORs] = 1.62-2.36). Inclusion of controls for exogenous demographic characteristics, psychiatric comorbidities and health behaviors, and adult social and economic statuses attenuated but did not eliminate observed associations between ADHD and poorer adult health. Conclusion: Research on adult health outcomes for those with ADHD should include consideration of the mechanisms by which a diagnosis of ADHD leads to cumulative social disadvantages that independently contribute to poorer health outcomes.


Medicina ◽  
2020 ◽  
Vol 56 (10) ◽  
pp. 501
Author(s):  
Yeonghee Eun ◽  
Kyung-Do Han ◽  
Da Hye Kim ◽  
In Young Kim ◽  
Eun-Jung Park ◽  
...  

Background and objectives: Hyperuricemia is one of the well-known cardiovascular risk factors. There is a growing interest in the association between hyperuricemia and arrhythmia. We used the representative sample data of Korean population to study the association between hyperuricemia and heart rate irregularity (HRI) that reflects total arrhythmia. Materials and Methods: We performed weighted multivariate logistic regression analysis to assess the association between hyperuricemia and HRI. Results: Of the 10,827 subjects, 1308 (13.2%) had hyperuricemia and 130 (1%) had HRI. In the presence of hyperuricemia, HRI was three times higher than that in the absence of hyperuricemia (OR 2.98, 95% CI 1.71–5.18). The risk of HRI was highest in subjects with both hypertension and hyperuricemia. In the subgroup analysis, the association of hyperuricemia with HRI was most pronounced in the smoker group. Conclusions: Hyperuricemia was highly correlated with HRI in adult Korean representative sample data. Hyperuricemia was associated with a nearly tripled risk for HRI. Hypertension has a synergistic effect with hyperuricemia on HRI. Further research is warranted to clarify the relationship between hyperuricemia and arrhythmia and its mechanism.


2020 ◽  
Vol 1 (1) ◽  
pp. 82-89
Author(s):  
Juan Gutiérrez Cebollada ◽  
Eva Baillés ◽  
Meritxell Girvent ◽  
Elisabeth Moyano ◽  
Pilar Larramona ◽  
...  

En los estudios de Medicina del Campus Mar de Barcelona (UPF-UAB, aunque todavía no se ha implementado la prueba ECOE recomendada por la Conferencia Nacional de Decanos de Facultades de Medicina (CNDFM), todos los estudiantes realizan durante su último año una ECOE diseñada por la administración sanitaria catalana. Nos planteamos realizar un estudio para establecer la posible concordancia entre los resultados en la prueba ECOE externa y los obtenidos en nuestro centro. También se pretendió establecer la relación entre los resultados en la ECOE y en la prueba MIR. El estudio se realizó con todos los graduados de las cuatro primeras promociones del grado en Medicina de la UPF-UAB que habían realizado la prueba ECOE y la prueba MIR. No se encontraron diferencias entre sexos en los resultados de la ECOE. Tanto en hombres como en mujeres, existió una relación positiva y significativa entre los resultados de la ECOE y los del expediente final y los de la prueba MIR.  Los resultados son valorados positivamente  ya que el expediente final está en consonancia con el rendimiento en una prueba donde presuntamente se evalúan de forma adecuada las competencias más relevantes que tendrían que tener los  graduados en Medicina. La relación positiva entre ECOE y MIR permite cierta tranquilidad hasta que en algún momento pueda implementarse una prueba no exclusivamente cognitiva para el acceso a la formación especializada. In the Medicine studies of the Campus Mar in Barcelona (UPF-UAB) the OSCE test recommended by the Conference of Deans of Spain has not yet been implemented, but all the students take an OSCE designed by the Catalan health administration during their final year. We plan to carry out a study to establish the possible relationship between the results in the external ECOE test and those obtained in our Medical School. We also tried to establish the relationship between the results in the ECOE and in the MIR test. The study was carried out with all the graduates of the first four promotions of the UPF-UAB degree in Medicine who had taken the ECOE test and the MIR test. No differences between sexes were found in the OSCE achievement. In both men and women, there was a positive and significant relationship between the results of the OSCE and those of the final score and those of the MIR test. The results are positively valued since the final score is in line with the performance in a test where presumably the most relevant competencies that graduates in Medicine should have are adequately evaluated. The positive relationship between OSCE and MIR allows some peace of mind until at some point an exam can be implemented that assesses clinical and communication skills for access to specialized training.


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