scholarly journals Global Fluoroquinolone Resistance Epidemiology and Implictions for Clinical Use

2012 ◽  
Vol 2012 ◽  
pp. 1-37 ◽  
Author(s):  
Axel Dalhoff
Keyword(s):  
Urinary Tract ◽  
Rural Areas ◽  
Methicillin Resistance ◽  
Bacterial Species ◽  
Fluoroquinolone Resistance ◽  
Sexually Transmitted ◽  
Tract Infections ◽  
Almost All ◽  
Healthcare Associated ◽  
Resistance Rates

This paper on the fluoroquinolone resistance epidemiology stratifies the data according to the different prescription patterns by either primary or tertiary caregivers and by indication. Global surveillance studies demonstrate that fluoroquinolone resistance rates increased in the past years in almost all bacterial species exceptS. pneumoniaeandH. influenzae, causing community-acquired respiratory tract infections. However, 10 to 30% of these isolates harbored first-step mutations conferring low level fluoroquinolone resistance. Fluoroquinolone resistance increased in Enterobacteriaceae causing community acquired or healthcare associated urinary tract infections and intraabdominal infections, exceeding 50% in some parts of the world, particularly in Asia. One to two-thirds of Enterobacteriaceae producing extended spectrum -lactamases were fluoroquinolone resistant too. Furthermore, fluoroquinolones select for methicillin resistance inStaphylococci.Neisseria gonorrhoeaeacquired fluoroquinolone resistance rapidly; actual resistance rates are highly variable and can be as high as almost 100%, particularly in Asia, whereas resistance rates in Europe and North America range from <10% in rural areas to >30% in established sexual networks. In general, the continued increase in fluoroquinolone resistance affects patient management and necessitates changes in some guidelines, for example, treatment of urinary tract, intra-abdominal, skin and skin structure infections, and traveller’s diarrhea, or even precludes the use in indications like sexually transmitted diseases and enteric fever.

Bacteremia due to healthcare-associated urinary tract infections in children

2021 ◽  
Vol 28 (2) ◽  
pp. 147-149
Author(s):  
F. Devrim ◽  
İ. Çağlar ◽  
N. Demiray ◽  
Y. Oruç ◽  
Y. Ayhan ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Tract Infections ◽  
Healthcare Associated

scholarly journals Trends in Nursing Research on Infections: Semantic Network Analysis and Topic Modeling

2021 ◽  
Vol 18 (13) ◽  
pp. 6915
Author(s):  
Jongsoon Won ◽  
Kyunghee Kim ◽  
Kyeong-Yae Sohng ◽  
Sung-Ok Chang ◽  
Seung-Kyo Chaung ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Network Analysis ◽  
Infection Control ◽  
Urinary Tract Infections ◽  
Bacterial Infections ◽  
Semantic Network ◽  
People Living With Hiv ◽  
Transmitted Infection ◽  
Sexually Transmitted ◽  
Tract Infections

Background: Many countries around the world are currently threatened by the COVID-19 pandemic, and nurses are facing increasing responsibilities and work demands related to infection control. To establish a developmental strategy for infection control, it is important to analyze, understand, or visualize the accumulated data gathered from research in the field of nursing. Methods: A total of 4854 articles published between 1978 and 2017 were retrieved from the Web of Science. Abstracts from these articles were extracted, and network analysis was conducted using the semantic network module. Results: ‘wound’, ‘injury’, ‘breast’, “dressing”, ‘temperature’, ‘drainage’, ‘diabetes’, ‘abscess’, and ‘cleaning’ were identified as the keywords with high values of degree centrality, betweenness centrality, and closeness centrality; hence, they were determined to be influential in the network. The major topics were ‘PLWH’ (people living with HIV), ‘pregnancy’, and ‘STI’ (sexually transmitted infection). Conclusions: Diverse infection research has been conducted on the topics of blood-borne infections, sexually transmitted infections, respiratory infections, urinary tract infections, and bacterial infections. STIs (including HIV), pregnancy, and bacterial infections have been the focus of particularly intense research by nursing researchers. More research on viral infections, urinary tract infections, immune topic, and hospital-acquired infections will be needed.

scholarly journals Quinolones for the Treatment ofNeisseria GonorrhoeaeandChlamydia Trachomatis

1993 ◽  
Vol 1 (2) ◽  
pp. 108-113 ◽  
Author(s):  
Sebastian Faro
Keyword(s):  
Urinary Tract ◽  
Soft Tissue ◽  
Chlamydia Trachomatis ◽  
Urinary Tract Infections ◽  
Single Agent ◽  
Moderate Activity ◽  
Sexually Transmitted ◽  
Tract Infections

The most commonly sexually transmitted bacteria areNeisseria gonorrhoeaeandChlamydia trachomatis.The quinolones ofloxacin and ciprofloxacin have been shown to have activity against both of these bacteria in vitro and in vivo. Ofloxacin is particularly well suited for the treatment ofN. gonorrhoeaeandC. trachomatiscervical infection, which can be considered the earliest manifestation of pelvic inflammatory disease (PID). Not only can ofloxacin be effectively used as a single agent, it is also useful in treating urinary tract infections caused by Enterobacteriaceae. Although it has moderate activity against anaerobes in general, ofloxacin does have activity against the anaerobes commonly isolated from female patients with soft tissue pelvic infections. Thus, ofloxacin has the potential for being utilized to treat early salpingitis.

scholarly journals Prevalence of Reproductive Tract Infections/Sexually Transmitted Infections among Rural Married Women – A Community Based Study Using Syndromic Approach

Healthline ◽  
2020 ◽  
Vol 11 (2) ◽  
pp. 72-81
Author(s):  
Anita Punia ◽  
Jyoti Yadav ◽  
Babita ◽  
Sanjay Kumar Jha ◽  
Sanjeet Singh ◽  
...  
Keyword(s):  
Reproductive Health ◽  
Sexually Transmitted Infections ◽  
Rural Areas ◽  
Reproductive Tract ◽  
Married Women ◽  
Reproductive Tract Infections ◽  
Community Based ◽  
Sexually Transmitted ◽  
Syndromic Approach ◽  
Tract Infections

Introduction: Reproductive Tract Infections (RTIs) and Sexually transmitted infections (STIs) continue to be a major public health problem and affecting women's health. Objectives: To estimate the prevalence of RTIs/STIs among married women aged 18-49 years in rural areas and to determine the factors associated with these conditions. Method: A community-based cross-sectional study was carried out among 308 eligible married women aged 18-49 years in rural areas in District Sonipat, Haryana using the WHO-Syndromic Approach for diagnosis of RTIs/STIs. Results: The mean age of study subjects in our study was 32.1 years (SD = ± 8.3 years) with a range from 18 to 49 years. The overall RTIs/STIs prevalence was 49.3%. The most frequent symptom was vaginal discharge (55.3%) followed by pain during micturition (34.2%), dyspareunia (26.9%), pain lower abdomen (24.3%) and vulval itching (16.4%). RTI/STI symptoms were found significantly more among women who had history of any chronic disease, who had irregular menstrual cycles, used cloths as sanitary pads and among those whose husbands were substance users. Conclusions: This study revealed a high prevalence (49.3%) of RTIs/STIs. Awareness about symptoms of RTIs, menstrual and personnel hygiene, raising literacy level of women, drive against use of addictive substances etc. by husbands is needed for control and prevention of RTIs. Primary health care services in respect of reproductive health should be strengthened and raising awareness among women about reproductive health issues through suitable communication strategies in order to bring about a positive behavior change for effective control of STIs.

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