scholarly journals A Study of Clinical, Microbiological, and Echocardiographic Profile of Patients of Infective Endocarditis

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Soumik Ghosh ◽  
Ratnakar Sahoo ◽  
Ranjit Kumar Nath ◽  
Nandini Duggal ◽  
Adesh Kumar Gadpayle

Infective endocarditis, a great masquerader, is a clinical entity which may present with a myriad of manifestations. Its changing epidemiological profile has been studied in the previous decades in both the developed and the developing nations. In this study, we strived to uphold the evolving clinical profile and its outcome from a government tertiary care hospital in Northern India. It was a descriptive, cross-sectional, observational study conducted over two years’ period involving 44 patients diagnosed with definite infective endocarditis, according to modified Dukes’ criteria. Demographic, clinical, microbiological, and echocardiographic data were analysed. Mean age of patients was 31 years. Rheumatic heart disease with regurgitant lesions was the commonest risk factor. Dyspnea and fever were the predominant symptom, and pallor and heart failure the commonest sign. Cultures were positive in 52% with Staphylococcus, the major isolate. Transesophageal echocardiography fared better than transthoracic one to define the vegetations. Mortality is reported in 4.5%. Prolonged duration of fever, pallor, hematuria, proteinuria, rheumatoid factor positivity, and large vegetations proved to be poor prognostic variables. Culture positive endocarditis, with persistent bacteremia, had higher incidence of acute renal failure. Right sided endocarditis was frequent in congenital lesions or IV drug user, whereas left sided endocarditis mostly presented with atrial fibrillation.

2019 ◽  
Vol 10 (5) ◽  
pp. 524 ◽  
Author(s):  
Reetu Agarwal ◽  
Loknandani Sharma ◽  
Ajay Chopra ◽  
Debdeep Mitra ◽  
Neerja Saraswat

2019 ◽  
Vol 6 (4) ◽  
pp. 1115 ◽  
Author(s):  
Raja Langer ◽  
Elias Sharma ◽  
Bhavna Langer ◽  
Rajiv K. Gupta ◽  
Rashmi Kumari ◽  
...  

Background: Erectile dysfunction (ED), though an important complication of T2DM is grossly under reported in this part of the world. The present study aimed to determine the prevalence and associated risk factors of ED in T2DM men in northern India.Methods: A cross-sectional study was conducted from January to August 2018 among male patients with T2DM in the medical OPD of a tertiary care teaching hospital in Jammu. IIEF- international index of erectile function was the tool used in the present study.Results: ED prevalence was 62.08%. Among socio-demographic variables, age was significantly associated with ED (p<0.05) while no association was found with education, occupation and family income. Smoking as a life style and hypertension as a co-morbid condition were significantly associated with ED (p<0.05). Duration of diabetes and type of diabetic complications were also found to be statistically significant.Conclusions: Prevalence of ED in T2DM men was quiet high in this region of India. Preventive interventions, early diagnosis and detection of T2DM along with treatment adherence to prevent diabetic complications is strongly recommended. Further research is recommended to establish temporal causality of ED in T2DM.


2021 ◽  
pp. 14-16
Author(s):  
Seema Aleem ◽  
Anjum Farhana ◽  
Humaira Bashir

Introduction: Hepatitis B and Hepatitis C share common transmission routes with HIV and coinfection with either can lead to adverse clinical outcomes in patients. This study planned to estimate confections with HBV and HCV among HIV positive subjects at a single Integrated Testing and Counselling Center (ICTC) in Kashmir valley. Methods: The study employed a cross-sectional study design from 2017 to 2019. After pretest counselling all subjects underwent HIV testing as per National AIDS Control guidelines. HIV positive subjects were included in this study. Samples of HIV positive subjects were then tested for HBV by ELISA detecting HbsAg whereas HCV was diagnosed by Anti HCV antibodies and HCV-RNA. Data was entered in excel and analyzed using SPSS. Means and percentages were calculated for relevant variables. Results:Atotal of 20070 subjects were tested during the study period of which 34 (0.169%) were HIVpositive. Around 60% positive subjects were males. Co-infection with HBV was detected in 11.7% subjects whereas 8.8% had an HCV coinfection. One subject had coinfection with both HBV and HCV. There was no signicant association of coinfection with gender or age Conclusion:Considering the adverse impact of coinfection on disease course and outcome, screening for HBVand HCVshould be a component in diagnostic workup of all HIVpositive subjects followed by linkage with specialized treatment services


Author(s):  
Radhakrishnan A. ◽  
Seema S. Bansode-Gokhe

Background: Objective of the study was to study the epidemiological profile of study subjects benefited by Rajiv Gandhi Jeevandayee Arogya Yojana (RGJAY) and study the spectrum of surgical procedures/therapies/consultations. Methods: It was a hospital record –based retrospective cross sectional study. Approximately 7200 beneficiaries were enrolled in a year. This study was analyzed with 10% beneficiaries (730) data by the convenient purposeful sampling method. Data was analyzed by using SPSS 17 software. Results: The majority of the study subjects (34.7%) belonged to the age group of 40-59 years. The mean age was 38.6.More study subjects were males (55.1%). 99.9% of study subjects had come directly without any referral. 95.2% study subjects were orange ration card holders, 4.1% were yellow ration card holders.78.8% of study subjects got approval from RGJAY society, whereas pre authorization status was cancelled in13.6%.In total surgeries majority of the study subjects utilized orthopaedics surgery (16.3%).In total therapies majority utilized paediatric medical management (18.5%). In conservative management majority utilized cardiology (94.7%) and burns (5.2%). Conclusions: The majority of the study subjects belonged to the age group of 40-59 years. More were males. Majority had come directly without any referral. This reveals the increased awareness about RGJAY among people. This scheme is more utilized by orange ration card holders than yellow card holders. In total surgeries majority utilized orthopaedics surgery. In total therapies majority utilized paediatric medical management. In conservative management majority utilized cardiology and burns. 


2017 ◽  
Vol 4 (2) ◽  
pp. 490
Author(s):  
Ashwin T. ◽  
Tumbanatham A. ◽  
Siva Ranganathan Green ◽  
Jaya Singh K.

Background: Seizures are one of the important causes of morbidity and mortality in adults. There are many studies based on the old seizure and epilepsy classification system but there are only few studies on the clinical profile and cause of seizures. The present study attempted to explore the clinical and etiological profile of seizures in adults above 18 years of age in our tertiary care hospital.Methods: This was a cross sectional study on 100 seizure participants having EEG abnormality. Patient seizure type was classified according to clinical features. History taking and physical examination of all selected participants were done and investigations were done and recorded to find the etiology according to proforma.Results: GTCS was the most common seizure type accounting for 57%. Ischemic infarct was most common cause of post stroke seizures. Hypoglycemia was most common metabolic cause of seizures.  Bacterial meningitis was most common cause of seizures due to infections. Stroke was the most common aetiology accounting for 21%. Focal seizures were seen predominantly in participants with calcified granuloma. In participants with alcohol withdrawal GTCS was the predominant seizure type.Conclusions: GTCS was the most common type of seizure in present study. Stroke was the most common cause of seizures and rheumatic heart disease was most common cause of seizures due to stroke in young participants. Seizures due to alcohol withdrawal were on the rise.


Author(s):  
Prachi D Sondankar ◽  
Shubhangi U Agawane ◽  
Abhay B Mane ◽  
Parvinder S Chawla

Introduction: The COVID-19 caused by Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2), has spread throughout the world from its place of origin in Wuhan city of China. From origin in December 2019 till May 2021, this disease affected 222 countries in the world with 152,534,452 confirmed cases. As on May 2021, India is the second worst affected country in the world. Aim: To know the epidemiological profile and clinical outcome of COVID-19 positive patients to help in understanding the disease dynamics. Materials and Methods: It was a cross-sectional, record based study at a tertiary care hospital. All the COVID-19 laboratory confirmed positive patients admitted from 15th June, 2020 to 15th September, 2020 were included in the study. Sample size was 1146. All the required data regarding patients were collected and analysed subsequently with the help of percentages, Z-test for proportion, Chi-square test and Odds ratio. Results: The mean age of the patients was 47.06 ±17.4 years ranging from 1 to 92 years. Males were significantly higher in numbers than females. 30.19% patients had some or other co-morbidities. 89.8% patients were discharged and 9.2% patients died. More number of deaths occurred in higher age group and highest death rate was seen in the patients who had multiple co-morbidities. Conclusion: The study concludes that most of the COVID-19 patients were middle aged and males were significantly more affected than females. Most of the patients were asymptomatic at the time of admission. It can be concluded that maximum patients had favourable clinical outcome as around 90% patients being discharged and case fatality rate was 9.2%. High rate of mortality was significantly associated with higher age and presence of co-morbidities.


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