scholarly journals Simultaneous Determination of Six Active Compounds in Yixin Badiranjibuya Granules, a Traditional Chinese Medicine, by RP-HPLC-UV Method

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Ning Yu ◽  
ChenHui He ◽  
Gulistan Awuti ◽  
Cheng Zeng ◽  
JianGuo Xing ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Rosmarinic Acid ◽  
Quality Evaluation ◽  
Scientific Basis ◽  
Determination Method ◽  
Rp Hplc ◽  
And Control ◽  
First Time

In this study, a sensitive, precise, and accurate HPLC-UV method was developed and validated to simultaneously determine the six analytes (luteolin-7-O-β-D-glucuronide, apigenin-7-O-β-D-glucuronide, diosmetin-7-O-β-D-glucuronide, acacetin-7-O-β-D-glucuronide, tilianin, and rosmarinic acid) in Yixin Badiranjibuya Granules, in which five analytes (i.e., luteolin-7-O-β-D-glucuronide, apigenin-7-O-β-D-glucuronide, diosmetin-7-O-β-D-glucuronide, acacetin-7-O-β-D-glucuronide, and rosmarinic acid) were determined for the first time in Yixin Badiranjibuya Granules, the content of tilianin in Yixin Badiranjibuya Granules was reported in other literatures, and the content of tilianin in our work was higher than that of the literature reports. The quality of 11 batch samples from four different manufacturers was evaluated using the proposed determination method. The contents of the six analytes were largely different among samples from various manufacturers. Therefore, this determination method can provide a scientific basis for quality evaluation and control of Yixin Badiranjibuya Granules.

Development of a Method for Simultaneous Determination of Two Stilbenes and Four Anthraquinones from Polygonum Cuspidatum by RP-HPLC

2019 ◽  
Vol 102 (1) ◽  
pp. 69-74 ◽  
Author(s):  
Jianye Yan ◽  
Yuanqing Wang ◽  
Hongnian Wu ◽  
Zhicheng Sun ◽  
Shihan Tan ◽  
...  
Keyword(s):  
Simultaneous Determination ◽  
Gradient Elution ◽  
Reversed Phase ◽  
Polygonum Cuspidatum ◽  
Chinese Medicinal Herb ◽  
Simple Method ◽  
Rp Hplc ◽  
First Time

Abstract Background: Polygonum Cuspidatum Sieb. et Zucc. (named Huzhang in China) is a traditional and popular Chinese medicinal herb used in removing jaundice, clearing heat-toxin, improving blood circulation, expelling stasis, dispelling wind and dampness, repelling phlegm, and suppressing cough. It is widely used in drug and functional food fields and distributed throughout the world, including in China, Japan, and North America. Objective: To control the quality of Polygonum Cuspidatum, an effective, reliable, and simple method for simultaneous determination of two stilbenes (polydatin, resveratrol) and four anthraquinones (emodin, physcion, rhein, and anthraglycoside B) was developed and validated for the first time in this study by reversed-phase HPLC (RP-HPLC). Methods: Separation was carried out on Agilent C18 column (250 × 4.6 mm I.D., 5 μm) with acetonitrile and 0.10% aqueous phosphoric acid as mobile phase and gradient elution at a flow rate of 0.8 mL/min. Detection was conducted with mobile wavelength at 30°C. Results: Good validation of the method including linearity, precision, repeatability, and recovery was performed. The contents of the studied analytes are significantly different, and resveratrol and rhein in particular existed in greater fluctuation among the samples. Conclusion: A simple, reliable, and sensitive method has been successfully established and applied to the analysis for simultaneous determination of the target compounds in 11 batches of samples. Highlights: Separation and quantitative analysis of two stilbenes and four anthraquinones from P. cuspidatum were developed by RP-HPLC. This method is convenient, sensitive, and accurate and can provide a reliable basis for further applications of P. cuspidatum in drug or food fields.

scholarly journals Preparation and Quality Evaluation of Soy Corn Yoghurt

2018 ◽  
Vol 2 ◽  
pp. 102-107
Author(s):  
Suman Lal Shrestha ◽  
Ram Shovit Yadav
Keyword(s):  
Statistical Analysis ◽  
Moisture Content ◽  
Sensory Evaluation ◽  
Storage Time ◽  
Quality Evaluation ◽  
Consumer Acceptability ◽  
Total Solids ◽  
And Control

Soy corn yoghurt is a vegan friendly product prepared by using soymilk as the major ingredient. The aim of this study was to assess the effect of corn milk addition (0, 10, 20, 25 & 30%) on the quality of soy yoghurt. The samples were subjected to sensory evaluation for consumer acceptability and data were subjected to statistical analysis. From sensory evaluation and statistical analysis 10% corn milk inclusion was selected as the best product (p<0.05). The yoghurt thus prepared using 10% corn milk had total solids 22.04%, moisture content 78.62%, protein 4.84%, fat 3.29%, carbohydrate 12.57%, ash 0.81%, acidity 0.68% and pH 4.58. Both control and 10% corn milk incorporated yoghurts were stored under refrigeration 6±1° C and analyzed at 2 days interval till 10 days. Yoghurts with corn milk and control were organoleptically acceptable up to 10 and 6 days respectively. Acidity and syneresis increased but pH decreased with storage time in both samples.

scholarly journals Determination of Bitterness of Andrographis Herba Based on Electronic Tongue Technology and Discovery of the Key Compounds of Bitter Substances

Molecules ◽  
2018 ◽  
Vol 23 (12) ◽  
pp. 3362 ◽  
Author(s):  
Xiao Zhang ◽  
Hongwei Wu ◽  
Xiankuo Yu ◽  
Hanyan Luo ◽  
Yaqi Lu ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
High Performance ◽  
Quality Evaluation ◽  
Herbal Remedy ◽  
Three Dimensional ◽  
Electronic Tongue ◽  
Principal Component ◽  
Chemical Compositions ◽  
Tcm Theory

Andrographis Herba (AH), the dry aerial segments of Andrographis paniculata (Burm.f.) Nees, is a common herbal remedy with bitter properties in traditional Chinese medicine (TCM) theory. Although bitterness is one of the features representing Chinese medicine, it has not been implemented as an index to assess the quality and efficacy of TCM because of peoples’ subjectivity to taste. In this study, 30 batches of AH with different commercial classifications (leaves, stems, or mixtures of both) were collected. Bitterness of AH was quantified by electronic tongue technology. Meanwhile, chemical compositions were characterized through establishing high-performance liquid chromatography fingerprints. The result indicated that the radar curves of the bitterness from different AH commercial classifications displayed different taste fingerprint information. Based on six taste factors, a Principal Component Analysis (PCA) score three-dimensional (3D) plot exhibited a clear grouping trend (R2X, 0.912; Q2, 0.763) among the three different commercial classifications. Six compounds (Peaks 2, 3, 4, 6, 7, 8) with positive correlation to bitterness were discovered by a Spearman correlation analysis. Peaks 2, 6, 7, 8 were identified as andrographolide, neoandrographolide, 14-deoxyandrographolide, and dehydroandrographolide, respectively. The electronic tongue can be used to distinguish AH samples with different commercial classifications and for quality evaluation.

scholarly journals A Comprehensive and Rapid Quality Evaluation Method of Traditional Chinese Medicine Decoction by Integrating UPLC-QTOF-MS and UFLC-QQQ-MS and its Application

Molecules ◽  
2019 ◽  
Vol 24 (2) ◽  
pp. 374 ◽  
Author(s):  
Yinfang Chen ◽  
Riyue Yu ◽  
Li Jiang ◽  
Qiyun Zhang ◽  
Bingtao Li ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Quality Evaluation ◽  
Synergistic Effects ◽  
Multiple Reaction Monitoring ◽  
Great Influence ◽  
Water As Solvent ◽  
And Control

Decoction is one of the oldest forms of traditional Chinese medicine and it is widely used in clinical practice. However, the quality evaluation and control of traditional decoction is a challenge due to the characteristics of complicated constituents, water as solvent, and temporary preparation. ShenFu Prescription Decoction (SFPD) is a classical prescription for preventing and treating many types of cardiovascular disease. In this article, a comprehensive and rapid method for quality evaluation and control of SFPD was developed, via qualitative and quantitative analysis of the major components by integrating ultra-high-performance liquid chromatography equipped with quadrupole time-of-flight mass spectrometry and ultra-fast-performance liquid chromatography equipped with triple quadrupole mass spectrometry. Consequently, a total of 39 constituents were tentatively identified in qualitative analysis, of which 21 compounds were unambiguously confirmed by comparing with reference substances. We determined 13 important constituents within 7 min by multiple reaction monitoring. The validated method was applied for determining five different proportion SFPDs. It was found that different proportions generated great influence on the dissolution of constituents. This may be one of the mechanisms for which different proportions play different synergistic effects. Therefore, the developed method is a fast and useful approach for quality evaluation of SFPD.

scholarly journals The Impact of the Quality of Tap Water and the Properties of Installation Materials on the Formation of Biofilms

Water ◽  
2019 ◽  
Vol 11 (9) ◽  
pp. 1903 ◽  
Author(s):  
Dorota Papciak ◽  
Barbara Tchórzewska-Cieślak ◽  
Andżelika Domoń ◽  
Anna Wojtuś ◽  
Jakub Żywiec ◽  
...  
Keyword(s):  
Tap Water ◽  
Galvanized Steel ◽  
Phosphorus Compounds ◽  
Plate Count ◽  
Nickel Steel ◽  
Quantitative Analyses ◽  
The Impact ◽  
First Time

The article presents changes in the quality of tap water depending on time spent in installation and its impact on the creation of biofilms on various materials (polyethylene (PE), polyvinyl chloride (PVC), chrome-nickel steel and galvanized steel). For the first time, quantitative analyses of biofilm were performed using methods such as: Adenosine 5’-triphosphate (ATP) measurement, flow cytometry, heterotrophic plate count and using fractographical parameters. In the water, after leaving the experimental installation, the increase of turbidity, content of organic compounds, nitrites and nitrates was found, as well as the decrease in the content of chlorine compounds, dissolved oxygen and phosphorus compounds. There was an increase in the number of mesophilic and psychrophilic bacteria. In addition, the presence of Escherichia coli was also found. The analysis of the quantitative determination of microorganisms in a biofilm indicates that galvanized steel is the most susceptible material for the adhesion of microorganisms. These results were also confirmed by the analysis of the biofilm morphology. The roughness profile, the thickness of the biofilm layer can be estimated at about 300 μm on galvanized steel.

Quality evaluation ofCordyceps through simultaneous determination of eleven nucleosides and bases by RP-HPLC

2006 ◽  
Vol 29 (7) ◽  
pp. 953-958 ◽  
Author(s):  
Li Yu ◽  
Jing Zhao ◽  
Shao Ping Li ◽  
Hui Fan ◽  
Min Hong ◽  
...  
Keyword(s):  
Simultaneous Determination ◽  
Quality Evaluation ◽  
Rp Hplc

scholarly journals Determining the Degree of Characteristics for Internet of Healthcare Devices Using Fuzzy ANP

2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Lin Wen
Keyword(s):  
Health Sector ◽  
Analytic Network Process ◽  
Care Quality ◽  
Fuzzy Anp ◽  
Heterogeneous Devices ◽  
Network Process ◽  
Iot Devices ◽  
And Control

With the revolution in Internet and digital technology, every organization is adopting digital things to carry out their day-to-day activities. Internet of Things (IoT) is a concept that is used to connect various devices over the Internet to increase the production and quality of service, deliver a huge amount of data in seconds, and automate the processes. IoT implementation in the health sector has changed the typical setup into smart and intelligent setup. With the “smart” and “Intelligent” abilities of IoT devices such as sensors and with the collaboration of humans and computers, physical processes can be monitored and, based on the received data, optimal decisions can ultimately be taken. IoT applications in healthcare will increase flexibility, patient’s care, quality of health, and control of diseases. As the IoT combines various heterogeneous devices and the inappropriate determination of the degree of characteristics for Internet of healthcare (IoH) devices may affect the efficiency of services, this research is carried out with the use of decision support system and application of fuzzy analytic network process (fuzzy ANP) was used for optimal determination of the degree of characteristics for IoH devices based on unique properties which would greatly increase the efficiency of industry. The experimental results are efficient and show the usefulness of the approach.

scholarly journals Functional fitness and quality of life of elderly Lian Gong, Tai Chi, and Qigong practitioners

2020 ◽  
Author(s):  
Márcia Regina Martinez Tedeschi ◽  
Tatiane Assone ◽  
Mauro Ferreira ◽  
Káren Mendes Jorge de Souza
Keyword(s):  
Quality Of Life ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
The Body ◽  
Control Group ◽  
Case Group ◽  
Functional Fitness ◽  
And Control ◽  
Body Practices

Abstract BACKGROUND Long-term regular physical activity, such as body practices of Traditional Chinese Medicine, seems to be an important habit for maintaining the functional fitness, independence and quality of life of elderly individuals. However, scientific knowledge production concerning assessment of such practices, specifically for the elderly population, focusing on functional fitness and quality of life, is still modest. Moreover, there is a lack of studies with long-term follow-up and control groups. Therefore, this study aims to compare the parameters of functional fitness and the dimensions of quality of life of elderly participants and non-participants in the body practices of Traditional Chinese Medicine. Longer adherence time, shorter adherence time and control group have been considered. METHODS This is an observational epidemiological case-control study carried out with 118 elderly individuals (≥ 60 years). The case group was represented by 59 elderly people practicing the body practices of Traditional Chinese Medicine, and they were subdivided into two groups, according to their median adherence time (< 24 months and ≥ 24 months). The control group was composed of 59 participants who were not participating in physical activity programs or guided body practices. Collection was carried out in four Traditional Medicine Specialized Units of the Municipal Health Office of the city of São Paulo. Sociodemographic and functional variables were collected. Quality of life was measured by Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36). For data analysis, a univariate logistic regression and the Kruskal Wallis test have been performed. RESULTS When assessing quality of life, favorable results were found for the case group, with longer (≥ 24 months) adherence time in the domains of bodily pain (p = 0.003), vitality (p = 0.021), role emotional (p = 0.034), and mental health (p = 0.020). A better result was observed in the case group, with longer (≥ 24 months) adherence time in the functional 30-second chair stand test (p = 0.006). CONCLUSIONS The body practices of Traditional Chinese Medicine can contribute to quality of life, functional fitness, and lower limb strength.

scholarly journals Effects of age at first access to range area on pecking behaviour and plumage quality of free-range layer chickens

2015 ◽  
Vol 58 (1) ◽  
pp. 85-91 ◽  
Author(s):  
M. Petek ◽  
E. Topal ◽  
E. Cavusoglu
Keyword(s):  
Body Region ◽  
Control Group ◽  
Feather Pecking ◽  
Free Range ◽  
Commercial Company ◽  
Negative Effect ◽  
Layer Chickens ◽  
And Control ◽  
First Time

Abstract. The aim of this study was to investigate the effects of age on pecking behaviour and plumage quality of free-range laying hens during first access to range. Six hundred 16-week-old layer pullets obtained from a commercial company were housed in a experimental free-range house. The experimental house consisted of a slat-and-litter floor with range area and was divided into three similar pens. The pullets were randomly assigned to a control and two experimental groups according to age at first access to range area. The birds were allowed into the range area for the first time at 18, 20 and 22 weeks of age in the groups of treatment I, treatment II and control, respectively. Pecking behaviour and plumage quality of the birds were measured for 8-week intervals from 24 to 48 weeks of age. Total feather damage significantly increased with age in all groups (P < 0.040, P < 0.006, P < 0.001). Compared to the control group, birds allowed into the range area earlier had less feather damage. The feather score of the tail body region in all groups was significantly greater (more damage) than in the others (P < 0.001). There were no significant differences for the total pecking behaviour of the birds in the groups at 24, 32, 40 and 48 weeks of age. Incidents of gentle feather pecking in every period were more frequent, while aggressive pecking was less frequent (P < 0.026, P < 0.007, P < 0.001). It can be said that access to range area as early as possible at the beginning of the laying period may be useful to reduce the negative effect of feather pecking in free-range layer chickens.

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