scholarly journals Surgical Management of Life-Threatening Thyroid Haematoma following Occult Blunt Neck Trauma

2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Ronak Ved ◽  
Neil Patel ◽  
Michael Stechman
Keyword(s):  
Respiratory Distress ◽  
Follicular Adenoma ◽  
Definitive Treatment ◽  
Multinodular Goitre ◽  
Neck Trauma ◽  
Anterior Neck ◽  
Severe Respiratory Distress ◽  
Blunt Neck Trauma ◽  
Threatening Condition ◽  
Life Threatening

A 42-year-old man arrived at the emergency department in severe respiratory distress, requiring immediate intubation and ventilation. An emergency computed tomography (CT) neck scan identified a substantial haematoma within a multinodular goitre, necessitating an emergency total thyroidectomy. It was later discovered that the patient had been the victim of an assault involving blunt trauma to the anterior neck. Five days postoperatively the patient was extubated and was well enough to self-discharge the following day. Pathology revealed the lesion to be a ruptured follicular adenoma within his multinodular goitre. Signs of this rare but life-threatening condition may be subtle on initial presentation, particularly if the patient is obtunded. Patients with suspected blunt neck trauma should be observed for signs of respiratory distress. If this develops, the patient should be intubated to facilitate CT scan, and if thyroid haematoma is confirmed, emergency thyroidectomy is the definitive treatment.

scholarly journals Congenital bilateral choanal atresia- Endonasal endoscopic surgery- Report of two cases

2020 ◽  
Vol 24 (1) ◽  
pp. 85-89
Author(s):  
Sheikh Hasanur Rahman ◽  
Mohammad Idrish Ali ◽  
Kamrul Hasan Tarafder ◽  
Md Habibur Rahman ◽  
Rokeya Begum
Keyword(s):  
Respiratory Distress ◽  
Choanal Atresia ◽  
Neck Surgery ◽  
Charge Syndrome ◽  
Definitive Treatment ◽  
Threatening Condition ◽  
Life Threatening ◽  
History Of ◽  
Rubber Catheter ◽  
Medical University

Congenital choanal atresia (CCA) is the development failure of the nasal cavity to communicate with nasopharynx. It is an uncommon congenital anomaly of nose with an incidence of approximately 1 in 5000-7000 live births. Choanal atresia is caused by failure of resorption of the nasobuccal membrane during embryonic development. Choanal atresia has a significant association with CHARGE syndrome. Surgical intervention is recommended in the first weeks of life in bilateral cases because this is a life threatening condition. Two cases of congenital bilateral choanla atresia (CCA) was admitted in the department of Otolaryngology & Head-Neck Surgery at Bangabandhu Sheikh Mujib Medical University (BSMMU) with the complaints of intermittent attacks of cyanosis, dyspnea, respiratory distress and history of inability to take feeds. On examination both babies had respiratory distress, mucoid discharge from both nasal cavities. A soft rubber catheter was passed into both nares revealed the diagnosis of bilateral CCA which was confirmed by flexible nasoendoscopy. Bilateral CCA was managed with a nasopharyngeal airway. Surgery is the definitive treatment with two main approaches namely transnasal and transpalatal. We discuss successful management of two neonates with bilateral CCA by endonasal endoscopic approach. Bangladesh J Otorhinolaryngol; April 2018; 24(1): 85-89

Blunt Trauma to the Thyroid: A Case Report

2005 ◽  
Vol 71 (6) ◽  
pp. 518-521 ◽  
Author(s):  
Christine Weeks ◽  
Francis D. Moore ◽  
Stephen J. Ferzoco ◽  
Jonathan Gates
Keyword(s):  
Steering Wheel ◽  
Trauma Symptoms ◽  
Thyroid Lobe ◽  
Neck Trauma ◽  
Anterior Neck ◽  
Acute Setting ◽  
Early Intubation ◽  
Blunt Neck Trauma ◽  
Life Threatening ◽  
The Right

Thyroid injury is a rare phenomenon in cases of blunt neck trauma. Symptoms are often subtle or not present on initial exam and can be rapidly life-threatening when airway compromise ensues. We describe the case of a 50-year-old woman who developed neck pain and swelling, dysphagia, and hoarseness after a rear-end collision in which she was the restrained driver, hitting her anterior neck against the steering wheel. Neck CT revealed fragmentation and hematoma within the right thyroid lobe. Arteriogram showed no vascular injury to the neck. The patient was observed in the ICU and was discharged home 3 days later without operative intervention. We believe that in the acute setting, a stable traumatic thyroid hematoma without airway encroachment may be safely observed. Increasing size or compromise of airway integrity should be indications for early intubation and neck exploration.

scholarly journals Human Adenovirus 7-Associated Hemophagocytic Lymphohistiocytosis-like Illness: Clinical and Virological Characteristics in a Cluster of Five Pediatric Cases

2020 ◽  
Author(s):  
William R Otto ◽  
Edward M Behrens ◽  
David T Teachey ◽  
Daryl M Lamson ◽  
David M Barrett ◽  
...  
Keyword(s):  
Genetic Predisposition ◽  
Hemophagocytic Lymphohistiocytosis ◽  
Human Adenovirus ◽  
Adenovirus Type ◽  
Definitive Treatment ◽  
Cell Transplant ◽  
Hematopoietic Stem ◽  
Threatening Condition ◽  
Epidemiology Data ◽  
Life Threatening

Abstract Background Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening condition of immune dysregulation. Children often suffer from primary genetic forms of HLH, which can be triggered by infection. Others suffer from secondary HLH as a complication of infection, malignancy, or rheumatologic disease. Identifying the exact cause of HLH is crucial, as definitive treatment for primary disease is hematopoietic stem cell transplant. Adenoviruses have been associated with HLH but molecular epidemiology data are lacking. Methods We describe the clinical and virologic characteristics of 5 children admitted with adenovirus infection during 2018–2019 who developed HLH or HLH-like illness. Detailed virologic studies, including virus isolation and comprehensive molecular typing were performed. Results All patients recovered; clinical management varied but included immunomodulating and antiviral therapies. A genetic predisposition for HLH was not identified in any patient. Adenovirus isolates were recovered from 4/5 cases; all were identified as genomic variant 7d. Adenovirus type 7 DNA was detected in the fifth case. Phylogenetic analysis of genome sequences identified 2 clusters—1 related to strains implicated in 2016–2017 outbreaks in Pennsylvania and New Jersey, the other related to a 2009 Chinese strain. Conclusions It can be challenging to determine whether HLH is the result of an infectious pathogen alone or genetic predisposition triggered by an infection. We describe 5 children from the same center presenting with an HLH-like illness after onset of adenovirus type 7 infection. None of the patients were found to have a genetic predisposition to HLH. These findings suggest that adenovirus 7 infection alone can result in HLH.

scholarly journals An Uncommon, Life-Threatening, Traumatic Hematoma in the Neck Area

2014 ◽  
Vol 2014 ◽  
pp. 1-3 ◽  
Author(s):  
Michalis Peroulis ◽  
Georgios D. Lianos ◽  
Vasilios Nousias ◽  
Zoi Anastasiadi ◽  
Aikaterini Lianou ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Penetrating Injury ◽  
Medical Attention ◽  
Caucasian Woman ◽  
Neck Trauma ◽  
Direct Evaluation ◽  
Blunt Neck Trauma ◽  
Neck Area ◽  
Life Threatening ◽  
Anatomical Area

It is well known that blunt neck trauma, when compared to a penetrating injury in the same anatomical area, is very rare. We report a case of an 81-year-old Caucasian woman with a blunt life-threatening neck trauma due to a bully goat. Although rare, direct evaluation should always be done in these cases because any misinterpretation may result in unfavorable outcomes. We have to highlight that close medical attention and prompt surgical treatment should be always considered in order to avoid dramatic consequences.

Traumatic Retropharyngeal Abscess of Insidious Onset -a case report and literature review (Preprint)

2018 ◽  
Author(s):  
Shuaib Kayode Aremu
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Retropharyngeal Abscess ◽  
Airway Compromise ◽  
Neck Trauma ◽  
Anterior Neck ◽  
Insidious Onset ◽  
Life Threatening

UNSTRUCTURED Retropharyngeal abscess is an abscess of the deep spaces in the neck which if not treated urgently can be life-threatening as a result of airway compromise. It is important to detect and treat very early. It may arise in pediatrics from direct neck trauma which is not very common and fishbone impaction. Direct anterior neck trauma resulting in insidious retropharyngeal abscess has not been widely reported.

scholarly journals A Possible Path towards Rapid Development of Live-Attenuated SARS-CoV-2 Vaccines: Plunging into the Natural Pool

Biomolecules ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. 1438
Author(s):  
German Todorov ◽  
Vladimir N. Uversky
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Respiratory Distress ◽  
Vaccine Development ◽  
Wide Spectrum ◽  
Rapid Development ◽  
Healthcare Systems ◽  
Severe Respiratory Distress ◽  
The World ◽  
Fast Development ◽  
Life Threatening

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the causative agent of the coronavirus disease 2019 (COVID-19) pandemic spreading around the world, causing massive distress to the world’s economy and affecting healthcare systems worldwide. Although some exposed individuals have no symptoms and most symptomatic infections are not severe, COVID-19 cases span a wide spectrum, ranging from mild to critical and sometimes resulting in life-threatening complications, such as pneumonia, severe respiratory distress and cardiac problems. Currently, there is no curative drug for COVID-19 and vaccines are still under development. We are presenting here a strategy for the fast development of natural live-attenuated SARS-CoV-2 vaccines. Our proposed approach is based on screening for, identifying, analyzing and selecting naturally attenuated yet highly immunogenic SARS-CoV-2 strains, which may lead to a shorter cycle of vaccine development, as well as higher vaccine effectiveness.

Epidemiology of Neonatal Disorders of Respiration

1991 ◽  
Vol 7 (S1) ◽  
pp. 9-15 ◽  
Author(s):  
Ola Hjalmarson
Keyword(s):  
Respiratory Distress ◽  
Chest Wall ◽  
Prognostic Significance ◽  
Newborn Infants ◽  
Breathing Frequency ◽  
Threatening Condition ◽  
Life Threatening

It is well known that signs of respiratory distress or disease (RD), such as high breathing frequency, chest wall retractions, grunting, and cyanosis, are common in newborn infants. The signs may be very transient or develop into a potentially life-threatening condition. When they are first observed, they often have a very ambiguous prognostic significance.

The First Case of Multisystem Inflammatory Syndrome in Children Successfully Treated with Combined Therapies Including Extracorporeal Membrane Oxygenation and Plasmapheresis

2021 ◽  
Author(s):  
Capan Konca ◽  
Ayse B. Anil ◽  
Onur Isik ◽  
Emine P. Kulluoglu ◽  
Doga Luleyap ◽  
...  
Keyword(s):  
Extracorporeal Membrane Oxygenation ◽  
Severe Disease ◽  
Anticoagulation Therapy ◽  
Definitive Treatment ◽  
Membrane Oxygenation ◽  
First Case ◽  
Threatening Condition ◽  
Child Patient ◽  
Life Threatening ◽  
Inflammatory Syndrome

AbstractMultisystem inflammatory syndrome in children (MIS-C) is a severe disease that can lead to death. There is no definitive treatment for MIS-C yet. It has been reported that intravenous immunoglobulin, intravenous methylprednisolone, fluid supplements, antibiotics, inotropics, extracorporeal membrane oxygenation (ECMO), plasmapheresis, biological therapy, and anticoagulation therapy can be used for treatment. In this article, we presented an 8-year-old girl child patient who survived due to timely administered ECMO and combined therapies including plasmapheresis without any sequela despite her life-threatening condition due to MIS-C.

scholarly journals Acute respiratory distress syndrome: An update and review

2018 ◽  
Vol 6 (2) ◽  
pp. 74-77 ◽  
Author(s):  
Gautam Rawal ◽  
Sankalp Yadav ◽  
Raj Kumar
Keyword(s):  
Acute Respiratory Distress Syndrome ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Distress Syndrome ◽  
Rescue Therapy ◽  
Severe Hypoxemia ◽  
Low Tidal Volume ◽  
The Past ◽  
Threatening Condition ◽  
Life Threatening

Abstract Acute respiratory distress syndrome (ARDS) is a life threatening condition characterized by severe hypoxemia due to pulmonary gas exchange failure and was first recognized in 1960s.Since its first description, it has undergone intensive research in the past few decades to understand its pathogenesis and therapies. Despite this, the recommended therapies to decrease mortality in ARDS remain limited and include low-tidal volume mechanical ventilation, prone ventilation and recently, the ECMO rescue therapy in extreme cases. This review article will summarize the key features of ARDS with a brief overview of the therapeutic options in the management of ARDS.

Rhinosporidiosis of trachea: a clinical cause for concern

2008 ◽  
Vol 122 (4) ◽  
Author(s):  
R Arora ◽  
R Gupta ◽  
Amit Kumar Dinda
Keyword(s):  
Sri Lanka ◽  
Respiratory Distress ◽  
Rare Complication ◽  
Pathological Examination ◽  
Complete Excision ◽  
Severe Respiratory Distress ◽  
Risk Of Bleeding ◽  
Emergency Tracheostomy ◽  
Bronchoscopic Biopsy ◽  
Life Threatening

AbstractBackground:Rhinosporidiosis is a granulomatous infection usually affecting the nasal mucosa and conjunctiva. The disease is widely prevalent in India and Sri Lanka. Tracheo-bronchial involvement is extremely rare and is potentially life threatening. Diagnosis of tracheal involvement is a challenge due to the risk of bleeding during attempted bronchoscopic biopsy.Case:A 73-year-old man was admitted with severe respiratory distress, for which emergency tracheostomy was performed. At tracheostomy, a fleshy mass was seen emerging from the wound. Pathological examination of the mass confirmed rhinosporidiosis involving the trachea. Complete excision of the mass was performed after initial stabilisation of the patient.Conclusion:Tracheo-bronchial rhinosporidiosis, a rare complication of nasopharyngeal infection, should be considered in a known case presenting with severe respiratory distress.

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