scholarly journals Myxedema Crisis Presenting with Seizures: A Rare Life-Threatening Presentation—A Case Report and Review of the Literature

2017 ◽  
Vol 2017 ◽  
pp. 1-5
Author(s):  
Sonali Sihindi Chapa Gunatilake ◽  
Uditha Bulugahapitiya
Keyword(s):  
Mortality Rate ◽  
High Mortality ◽  
Hormone Replacement ◽  
Clonic Seizure ◽  
Severe Form ◽  
Elderly Male ◽  
Organ Specific ◽  
Life Threatening ◽  
Sodium Correction ◽  
Very High

Myxedema crisis is a life-threatening extreme form of hypothyroidism with a high mortality rate if left untreated. Myxedema crisis is commonly seen in older patients, especially in women, and is associated with signs of hypothyroidism, hypothermia, hyponatraemia, hypercarbia, and hypoxemia. Patients might present with different organ specific symptoms. Seizures are a recognized but rare manifestation of myxedema with a very high mortality rate. Prompt diagnosis and appropriate management may improve the prognosis. Many contributory factors may involve development of seizures in a patient with myxedema. Hyponatraemia is one such cause, which is seen in moderate-severe form in the background of myxedema. We report an elderly male who presented with generalized tonic clonic seizure preceded by memory impairment and drowsiness. He had moderate hyponatraemia and very high thyroid stimulatory hormone levels in association with low free thyroxin levels. Diagnosis of myxedema crisis was made and patient was successfully treated with sodium correction and thyroid hormone replacement.

scholarly journals Ventricular septal rupture presented with chronic heart failure symptoms: a case report

2019 ◽  
Vol 3 (2) ◽  
Author(s):  
Ioannis Michelis ◽  
Ioannis Kontonasakis ◽  
Christina Tsakliadou ◽  
Nikolaos Kouvelas
Keyword(s):  
Myocardial Infarction ◽  
Heart Failure ◽  
Chronic Heart Failure ◽  
Mortality Rate ◽  
High Mortality ◽  
Medical Attention ◽  
Mechanical Complication ◽  
Ventricular Septal Rupture ◽  
Elective Repair ◽  
Very High

Abstract Background Ventricular septal rupture (VSR) is a rare mechanical complication following acute myocardial infarction, with very high mortality rate. Haemodynamic deterioration and cardiogenic shock is common in such cases. Rarely, however, patients may show only signs of chronic heart failure or be completely asymptomatic. Case summary We report a case of a 72-year-old male patient with VSR following a transmural myocardial infarction. He sought medical attention only after gradually experiencing symptoms of chronic heart failure, weeks after the onset of the myocardial infarction. The patient successfully underwent elective repair surgery, after optimizing the medical therapy and completing the necessary workup. Discussion Ventricular septal rupture repair is necessary in all cases due to the high mortality rate if left untreated. The timing of the operation, however, should be decided individually for every patient. Haemodynamically unstable patients may require early surgery, but in stable patients responding to medical treatment, delayed repair may be the best option.

scholarly journals Master of the Masquerade: An Atypical Presentation of Acute Aortic Dissection

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Ramy Mando ◽  
Daniel Tim ◽  
Anthony DeCicco ◽  
Justin Trivax ◽  
Ivan Hanson
Keyword(s):  
Mortality Rate ◽  
Early Diagnosis ◽  
Aortic Dissection ◽  
High Mortality ◽  
Acute Aortic Dissection ◽  
Atypical Presentation ◽  
Aggressive Management ◽  
Life Threatening

Acute aortic dissection (AAD) is associated with unacceptably high mortality rate. As such, early diagnosis and aggressive management are essential in order to avoid life-threatening complications. Herein, we report an atypical presentation of AAD and clinical sequelae.

scholarly journals An Uncommon Feature of Chronic Granulomatous Disease in a Neonate

2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Razieh Afrough ◽  
Sayyed Shahabeddin Mohseni ◽  
Setareh Sagheb
Keyword(s):  
Mortality Rate ◽  
Chronic Granulomatous Disease ◽  
High Mortality ◽  
Neonatal Period ◽  
Fungal Infections ◽  
Granuloma Formation ◽  
Granulomatous Disease ◽  
Life Threatening

Chronic Granulomatous Disease (CGD) represents recurrent life-threatening bacterial and fungal infections and granuloma formation with a high mortality rate. CGD’s sign and symptoms usually appear in infancy and children before the age of five; therefore, its presentation in neonatal period with some uncommon features may be easily overlooked. Here we describe a case of CGD in a 24-day-old boy, presenting with a diffuse purulent vesiculopustular rash and multiple osteomyelitis.

Giant iliac artery aneurysm

Open Medicine ◽  
2010 ◽  
Vol 5 (2) ◽  
pp. 156-158
Author(s):  
Murat Ugurlucan ◽  
Filiz Erdim ◽  
Ufuk Alpagut ◽  
Emin Tireli ◽  
Enver Dayioglu
Keyword(s):  
Mortality Rate ◽  
High Mortality ◽  
Iliac Artery ◽  
Vascular Malformations ◽  
Artery Aneurysm ◽  
Iliac Artery Aneurysm ◽  
Pelvic Region ◽  
Deep Location ◽  
Very High

AbstractIsolated iliac artery aneuryms are very rare vascular malformations. They can remain unnoticed for long periods of time because of their deep location in the pelvic region. Most of the patients present to the clinic with rupture of the aneurysm, and thus the condition has a very high mortality rate. We report here the case of an 84-year-old man with giant iliac artery aneuryms who was treated successfully by aneurysmectomy and aortoiliac bypass.

Lateral sinus thrombosis following myringoplasty: a rare complication

2012 ◽  
Vol 127 (S1) ◽  
pp. S39-S41 ◽  
Author(s):  
G Sim ◽  
F Lannigan
Keyword(s):  
Case Report ◽  
Mortality Rate ◽  
Otitis Media ◽  
High Mortality ◽  
Sinus Thrombosis ◽  
Rare Complication ◽  
Lateral Sinus ◽  
Lateral Sinus Thrombosis ◽  
Life Threatening ◽  
Life Threatening Complication

AbstractObjective:We report lateral sinus thrombosis occurring as a rare complication following a routine and uneventful otological procedure.Case report:Lateral sinus thrombosis is a rare but known complication of otitis media. It has not been documented as a complication of routine otological surgery. We present a case of this rare complication following a myringoplasty. We also discuss the presentation, investigation and treatment of lateral sinus thrombosis. It is essential to be able to recognise and treat this rare complication early, due to its high mortality rate.Conclusion:Lateral sinus thrombosis is a rare but potentially life-threatening complication. It is therefore essential for clinicians to be able to recognise and treat this condition early.

scholarly journals Bronchial complications after lung transplantation

2021 ◽  
Vol 23 (1) ◽  
pp. 140-149
Author(s):  
I. V. Pashkov ◽  
M. T. Bekov ◽  
S. V. Gautier
Keyword(s):  
Mortality Rate ◽  
Lung Transplantation ◽  
High Mortality ◽  
Postoperative Period ◽  
Life Threatening ◽  
Transplant Function

Bronchial complications are among the main causes of impairing postoperative period and thansplant failure. Severe bronchial complications are very rare but have a high mortality rate. Light forms decrease transplant function and while progressing can leads to life-threatening conditions without required treatment. Nowadays there is a huge necessity in classification of diagnostic and bronchial complications treatment on different terms after lung transplantation. Methods of observation bronchoscopy and interventional bronchology are allowing us to realize prevention, diagnostic and treatment bronchial complications.

scholarly journals Pathophysiological aspects of severe acute pancreatitis-associated lung injury

2005 ◽  
Vol 133 (1-2) ◽  
pp. 76-81 ◽  
Author(s):  
Maja Surbatovic ◽  
Krsta Jovanovic ◽  
Sonja Radakovic ◽  
Nikola Filipovic
Keyword(s):  
Acute Pancreatitis ◽  
Acute Lung Injury ◽  
Mortality Rate ◽  
Lung Injury ◽  
Severe Acute Pancreatitis ◽  
Distress Syndrome ◽  
Severe Form ◽  
Very High ◽  
Intensive Medicine

Acute pancreatitis is an inflammatory process which occurs in severe form in 20% of all patients, out of whom 1596-25% will die. The incidence of severe acute pancreatitis-associated lung injury (APALI) varies from 15% to 55% and its severity varies from mild hypoxemia to acute respiratory distress syndrome (ARDS). Acute lung injury (ALI) and ARDS are the most significant manifestations of extra abdominal dysfunctions in severe acute pancreatitis with mortality rate as high as 60% in the first week of the onset of illness. Different pathophysiological mechanisms of severe acute pancreatitis-associated lung injury have been described. The role of enzymes, adhesion molecules, neutrophils, fibronectin and various inflammatory mediators has been emphasized. Mechanism of the acute lung injury associated with the acute pancreatitis is very complex and has not been clear yet. There is no specific therapeutic procedure and mortality rate is very high. Therefore, further studies are necessary to address this acute and growing problem in intensive medicine.

scholarly journals Antiviral optical techniques as a possible novel approach to COVID-19 treatment

2021 ◽  
pp. 2130002
Author(s):  
Fereshteh Moshfegh ◽  
Farshad Khosraviani ◽  
Negar Moghaddasi ◽  
Seyedeh Fatemeh Seyed Javadi Limoodi ◽  
Ebrahim Boluki
Keyword(s):  
Mortality Rate ◽  
Viral Infection ◽  
Viral Infections ◽  
Definitive Treatment ◽  
Emerging Infections ◽  
Novel Technologies ◽  
Novel Approach ◽  
The World ◽  
Life Threatening ◽  
Very High

The current pandemic SARS-CoV-2 (also known as 2019-nCoV and COVID-19) viral infection is growing globally and has created a disastrous situation all over the world. One of the biggest challenges is that no drugs are available to treat this life-threatening disease. As no drugs are available for definitive treatment of this disease and the mortality rate is very high, there is an utmost need to cure the infection using novel technologies. This study will point out some new antimicrobial technologies that have great potentials for eradicating and preventing emerging infections. They can be considered as treatments of choice for viral infections in the future.

scholarly journals Akut coronariaszindróma ellátása – 2016

2016 ◽  
Vol 157 (38) ◽  
pp. 1500-1506
Author(s):  
Dávid Becker ◽  
Béla Merkely
Keyword(s):  
Acute Coronary Syndrome ◽  
Mortality Rate ◽  
High Mortality ◽  
Coronary Intervention ◽  
Continuous Development ◽  
Coronary Syndrome ◽  
Optimal Therapy ◽  
European Guidelines ◽  
Life Threatening ◽  
Care System

Acute coronary syndrome is a life threatening disease with high mortality rate without optimal therapy. Due to the continuous development in the treatment of the disease, the prognosis has dramatically improved over the last 30 years. Apart from the improvement of the medication, the most important factor is the availability of an immediate coronary intervention for everyone, at any time. Currently, nineteen interventional centers provide this care in Hungary, 24 hours a day. Thanks to the European guidelines, the care system is now more efficient in determining who and when needs the treatment. This article summarises the principles of the treatment currently in use. Orv. Hetil., 2016, 157(38), 1500–1506.

scholarly journals Pneumomediastinum Secondary to Acute Emphysematous Pyelonephritis

2020 ◽  
pp. 1-3
Author(s):  
Jessica Buicko ◽  
Anne M. Lopez ◽  
Jessica Buicko ◽  
Kenan B. Ashouri ◽  
Michael A. Lopez ◽  
...  
Keyword(s):  
Infectious Disease ◽  
Mortality Rate ◽  
High Mortality ◽  
Radiographic Finding ◽  
Secondary Process ◽  
Thoracic Cavity ◽  
Emphysematous Pyelonephritis ◽  
Wide Range ◽  
Very High

Pneumomediastinum is a clinical and radiographic finding that is associated with a wide range of acute processes that allow gas to disseminate through the tissues of mediastinum that often necessitates prompt consideration for thoracic intervention. In some circumstances, pneumomediastinum may arise from processes extrinsic to the thoracic cavity and is a secondary process arising from a primary retropharyngeal or retroperitoneal etiology. Acute emphysematous pyelonephritis is a rare and severe infectious disease of the kidney associated with a very high mortality rate. We report a case of advanced emphysematous pyelonephritis presenting with pneumomediastinum successfully treated with simple nephrectomy in the absence of any direct mediastinal intervention.

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