Ultrasound-Assisted, Base-Catalyzed, Homogeneous Reaction for Ferulic Acid Production from γ-Oryzanol

A method for producing ferulic acid by ultrasound-assisted, homogeneous, base-catalyzed hydrolysis of γ-oryzanol was developed. Experiments were conducted using various reaction temperatures and ratios of γ-oryzanol to base catalyst in both homogeneous and heterogeneous systems. The reaction performed without ultrasound under the homogeneous conditions of potassium hydroxide/γ-oryzanol ratio (wt/wt) 20 : 1 and 75°C gave a ferulic acid yield of 83.3% in 3 h. Acceleration of the homogeneous reaction using ultrasound irradiation at 20 (horn type) and 200 kHz (planar type) was explored by evaluating the kinetic parameters. At 30°C, the ratios of ultrasonic irradiation at low (20 kHz, 50 W) and high (200 kHz, 50 W) frequencies versus those of the heating method increased by 2.0- and 1.4-fold in comparison with those at 60°C, respectively. The contribution of ultrasonic irradiation (50 W) to the hydrolysis reaction decreased with increase of temperature. However, irradiation at 20 kHz and a power of 180 W gave a 94% ferulic acid yield at 60°C in 3 h. These results indicate that the use of low frequency (horn type and high-power irradiation) enabled yields higher than 90% to be obtained.

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Comparative Study on Conventional and Ultrasound Irradiation Promoted Synthesis of 2,3-Disubstitutedquinoxaline Derivatives

Al-Mustansiriyah Journal of Science ◽

10.23851/mjs.v28i3.207 ◽

2018 ◽

Vol 28 (3) ◽

pp. 141

Author(s):

Ahmed Mutanabbi Abdula ◽

Ghazwan Ali Salman ◽

Hamid H. Mohammed

Keyword(s):

13C Nmr ◽

Ultrasonic Irradiation ◽

Reaction Times ◽

Ultrasound Irradiation ◽

Conventional Heating ◽

Heating Method ◽

Quinoxaline Derivatives ◽

Ft Ir ◽

Ultrasound Assisted ◽

Good Percentage

A series of ten chalcone-substituted quinoxalines (4a-e), (3a-e) starting from 1-(phenylquinoxalin-2-yl)ethanone and 1-(3-methylquinoxalin-2-yl)ethanone have been synthesized using conventional heating and ultrasound-assisted methods. Furthermore, novel of five quinoxaline derivatives including pyrazoline, isoxazole, pyrimidin-2-one, N-acylpyrazoline and pyridin-2-one moieties were also prepared from the reaction of chalcone compound 4a with different cyclization reagents using the same strategy. The structures of all synthesized compounds were established on the basis of FT-IR, 1H-NMR and 13C-NMR. The ultrasonic irradiation method provide several advantages over conventional heating method, including shorter reaction times (30-90 min.) and good percentage yields (65% - 88%), comparing with conventional protocol (5 to 20 hrs. with 30% to 55% reaction yields).

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Glucose obtained from rice bran by ultrasound-assisted enzymatic hydrolysis

Ingeniería e Investigación ◽

10.15446/ing.investig.v35n2.49710 ◽

2015 ◽

Vol 35 (2) ◽

pp. 61-66 ◽

Cited By ~ 2

Author(s):

Raquel Cristine Kuhn ◽

Marcio Antonio Mazutti ◽

Edson Luiz Foletto ◽

Valéria Dal Prá ◽

Eduardo Zimmermann ◽

...

Keyword(s):

Enzymatic Hydrolysis ◽

Moisture Content ◽

Rice Bran ◽

Enzymatic Reaction ◽

Process Intensification ◽

Ultrasound Irradiation ◽

Enzyme Concentration ◽

Rate Period ◽

Ultrasound Assisted ◽

Hydrolysis Of

In this work ultrasound-assisted solid-state enzymatic hydrolysis of rice bran to obtain fermentable sugars was investigated. For this purpose, process variables such as temperature, enzyme concentration and moisture content were evaluated during the enzymatic hydrolysis with and without ultrasound irradiation. The enzyme used is a blend of amylases derived from genetically modified strains of Trichoderma reesei. Kinetic of the enzymatic hydrolysis of rice bran at the constant-reaction rate period were measured. The best results for the ultrasound-assisted enzymatic hydrolysis was obtained using 3 wt% of enzyme, 60 oC and moisture content of 65 wt%, yielding 0.38 g sugar/g rice bran, whereas for the hydrolysis in the absence of ultrasound the highest yield was 0.20 g sugar/g rice bran using 3 wt% of enzyme, 60 oC and moisture content of 50 wt%. The use of ultrasound-assisted enzymatic hydrolysis of rice bran was intensified, obtaining around 74% more fermentable sugar than in the absence, showing that the use of ultrasound is a promising technology to be used in enzymatic reaction as an alternative of process intensification.

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Directed evolution of feruloyl esterase from Lactobacillus acidophilus and its application for ferulic acid production

Bioresource Technology ◽

10.1016/j.biortech.2021.124967 ◽

2021 ◽

pp. 124967

Author(s):

Shujun Liu ◽

Lubna Soomro ◽

Xue Wei ◽

Xufeng Yuan ◽

Tianyi Gu ◽

...

Keyword(s):

Ferulic Acid ◽

Directed Evolution ◽

Lactobacillus Acidophilus ◽

Acid Production ◽

Feruloyl Esterase ◽

Ferulic Acid Production

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Ultrasound-Assisted Oxidative Desulfurization of Diesel Fuel in H2O2/Heteropoly Acid/Solvent System

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.1033-1034.85 ◽

2014 ◽

Vol 1033-1034 ◽

pp. 85-89 ◽

Cited By ~ 1

Author(s):

Guo Xian Yu ◽

Qian Zhong ◽

Mei Jin ◽

Ping Lu

Keyword(s):

Sulfur Content ◽

Ultrasonic Irradiation ◽

Diesel Fuel ◽

Oxidation Reaction ◽

Heteropoly Acid ◽

Oxidative Desulfurization ◽

Solvent System ◽

Oxidative Reaction ◽

Solvent Systems ◽

Ultrasound Assisted

Ultrasound-assisted oxidative desulfurization (UAODS) of diesel fuel in H2O2/Heteropoly acid/Solvent systems, was investigated. Effects of solvent, catalyst, ultrasound and reaction temperature on the oxidation desulfurization of diesel fuel were investigated. When MPA/oil was 2%wt, methanol/diesel fuel was 20%wt, ultrasound power was 400 W and ultrasound time was 10 min, the sulfur content of diesel fuel was decreased from 211 ppm to 19 ppm. The use of ultrasonic irradiation in H2O2/Heteropoly acid/Solvent system significantly improved the efficiency of the oxidation reaction, and solvent was helpful to make the oxidative reaction happen in the same one phase.

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Catalyst-free, one-pot, four-component green synthesis of functionalized 1-(2-fluorophenyl)-1,4-dihydropyridines under ultrasound irradiation

New Journal of Chemistry ◽

10.1039/c5nj03574k ◽

2016 ◽

Vol 40 (6) ◽

pp. 5107-5112 ◽

Cited By ~ 29

Author(s):

Nhlanhla Shabalala ◽

Suresh Maddila ◽

Sreekantha B. Jonnalagadda

Keyword(s):

Green Synthesis ◽

Ultrasonic Irradiation ◽

Aqueous Ethanol ◽

Ultrasound Irradiation ◽

One Pot ◽

Catalyst Free ◽

New Compounds ◽

Synthesis Protocol

A catalyst-free synthesis protocol for functionalized 1,4-dihydropyridines under ultrasonic irradiation in aqueous ethanol is reported with excellent yields. Eleven new compounds are synthesized using dimethylacetylenedicarboxylate, 2-fluoroaniline, malononitrile and various substituted aldehydes.

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Assessment of the Effects of Low-Frequency Ultrasound Irradiation Applied to Venous Ulcer Treatment / Avaliação dos Efeitos da Irradiação Ultrassônica de Baixa Frequência no Tratamento de Úlcera Venosa

Revista de Pesquisa Cuidado é Fundamental Online ◽

10.9789/2175-5361.2019.v11i5.1219-1225 ◽

2019 ◽

Vol 11 (5) ◽

pp. 1219

Author(s):

Vanessa Aguiar Ponte ◽

Thiago Moura De Araújo ◽

Alan Sidney Jacinto Da Silva ◽

Darrielle Gomes Alves Mororó ◽

Vivian Saraiva Veras

Keyword(s):

Low Frequency ◽

Ultrasound Irradiation ◽

Venous Ulcer ◽

Low Frequency Ultrasound ◽

Ulcer Treatment ◽

Frequency Ultrasound

Objetivo: Avaliar os efeitos da irradiação ultrassônica de baixa frequência no tratamento de úlcera venosa. Método: Estudo de aplicação de tecnologia em saúde, realizado com indivíduos com lesões venosas, no ano de 2017 entre os meses de abril a agosto, utilizado formulário estruturado para coleta, analisados no programa Excel e representados em tabela e estatística descritiva. Resultados: Participaram cinco pacientes, três mulheres entre 65 e 88 anos de idade. Os participantes apresentaram cinco úlceras venosas, maioria localizada na porção inferior da perna. Houve redução mínima de 2,5% e máxima de 35,8% sobre a área das lesões. Um participante apresentou 100,0% de epitelização e os demais apresentaram tecido de granulação maior ou igual a 70,0%. Encontrou-se redução máxima de 10 pontos na PUSH, redução mínima de 2 pontos. Conclusão: A terapia ultrassônica traz aspectos positivos para o processo de reparação tecidual.

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Efficient Production of Acetic Acid from Nipa (Nypa fruticans) Sap by Moorella thermoacetica (f. Clostridium thermoaceticum)

10.31227/osf.io/j2pt4 ◽

2019 ◽

Author(s):

Dung Van Nguyen ◽

Pinthep Sethapokin ◽

Harifara Rabemanolontsoa ◽

Eiji Minami ◽

Haruo Kawamoto ◽

...

Keyword(s):

Acetic Acid ◽

Oxalic Acid ◽

Acid Catalyst ◽

Cost Effective ◽

Efficient Production ◽

Acid Fermentation ◽

Acid Yield ◽

Moorella Thermoacetica ◽

Nypa Fruticans ◽

Hydrolysis Of

To valorize the underutilized nipa sap composed mainly of sucrose, glucose and fructose, acetic acid fermentation by Moorella thermoacetica was explored. Given that M. thermoacetica cannot directly metabolize sucrose, we evaluated various catalysts for the hydrolysis of this material. Oxalic acid and invertase exhibited high levels of activity towards the hydrolysis of the sucrose in nipa sap to glucose and fructose. Although these two methods consumed similar levels of energy for the hydrolysis of sucrose, oxalic acid was found to be more cost-effective. Nipa saps hydrolyzed by these two catalysts were also fermented by M. thermoacetica. The results revealed that the two hydrolyzed sap mixtures gave 10.0 g/L of acetic acid from the 10.2 g/L of substrate sugars in nipa sap. Notably, the results showed that the oxalic acid catalyst was also fermented to acetic acid, which avoided the need to remove the catalyst from the product stream. Taken together, these results show that oxalic acid hydrolysis is superior to enzymatic hydrolysis for the pretreatment of nipa sap. The acetic acid yield achieved in this study corresponds to a conversion efficiency of 98%, which is about 3.6 times higher than that achieved using the traditional methods. The process developed in this study therefore has high potential as a green biorefinery process for the efficient conversion of sucrose-containing nipa sap to bio-derived acetic acid.

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Ultrasonic Irradiation Of The Removal Of Linear Alkylbenzene Sulphonates (LAS) From Wastewater

Jurnal Teknologi ◽

10.11113/jt.v46.302 ◽

2012 ◽

Author(s):

Mohd Ariffin Abu Hassan ◽

Dionissios Mantzavinos ◽

Ian S. Metcalfe

Keyword(s):

Ultrasonic Irradiation ◽

Surfactant Concentration ◽

Degradation Rate ◽

Degradation Mechanism ◽

Low Frequency ◽

Degradation Pathway ◽

H2o2 Production ◽

Oh Radicals ◽

Linear Alkylbenzene ◽

Batch Time

Kesan frekuensi rendah (20 kHz) penyinaran ultrasonik untuk penyingkiran Linear Alkylbenzene Sulphonates (LAS) daripada larutan berair telah dikaji. Penyinaran ultrasonik terhadap tiga kepekatan berbeza LAS iaitu 500 μgmol/l, 750 μgmol/l and 1000 μgmol/l telah dijalankan. Kesemua eksperimen telah dijalankan pada suhu 30°C, pada frekuensi 20 kHz, kuasa pada 125 W dan masa eksperimen selama 120 minit tanpa pengawalan terhadap pH. Hasil kajian mendapati OH· radikal mendominasi proses pengdegradasian LAS. Kadar degradasi awal bertambah dengan bertambahnya kepekatan LAS di dalam skop kajian. Penghasilan H2O2 didapati rendah dengan proses penyinaran ultrasonik terhadap LAS pada kepekatan LAS yang tinggi. Keputusan penyinaran ultrasonik terhadap LAS dengan kehadiran Br¯ sebagai pemakan radikal membuktikan bahawa OH· radikal mendominasi pengdegradasian LAS. Kata kunci: Surfaktan, ultrasonik, sisa air, jumlah karbon organik (TOC) The effect of low frequency (20 kHz) ultrasonic irradiation on the removal of sodium Linear Alkylbenzene Sulphonates (LAS) from aqueous solutions has been investigated. Sonication of three different initial concentrations of LAS, 500 μgmol/l, 750 μgmol/l and 1000 μgmol/l, were performed. All experiments used a temperature of 30°C, frequency of 20 kHz, power of 125 W, a batch time of 120 min and the pH was left uncontrolled. It was found that the main degradation of LAS at micromolar concentrations proceeded via a reaction with OH· radicals. The initial degradation rate increased with an increase in the surfactant concentration over the whole concentration range studied. The sonolysis of LAS showed a strong inhibition of H2O2 production at a higher concentration. Sonication of LAS in the presence of Br¯ suggested that OH· radicals induced degradation pathway was the dominating sonochemical degradation mechanism. Key words: Surfactants, ultrasonic, wastewater, total organic carbon (TOC)

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Optimization of an Ultrasound-Assisted Extraction Condition for Flavonoid Compounds from Cocoa Shells (Theobroma cacao) Using Response Surface Methodology

Molecules ◽

10.3390/molecules24040711 ◽

2019 ◽

Vol 24 (4) ◽

pp. 711 ◽

Cited By ~ 7

Author(s):

Arief Md Yusof ◽

Siti Abd Gani ◽

Uswatun Zaidan ◽

Mohd Halmi ◽

Badrul Zainudin

Keyword(s):

Response Surface Methodology ◽

Response Surface ◽

Ethanol Concentration ◽

Irradiation Time ◽

Ultrasound Irradiation ◽

Coefficient Of Determination ◽

Ultrasound Assisted Extraction ◽

Assisted Extraction ◽

Ultrasound Assisted ◽

Experimental Values

This study investigates the ultrasound-assisted extraction of flavonoids from Malaysian cocoa shell extracts, and optimization using response surface methodology. There are three variables involved in this study, namely: ethanol concentration (70–90 v/v %), temperature (45–65 °C), and ultrasound irradiation time (30–60 min). All of the data were collected and analyzed for variance (ANOVA). The coefficient of determination (R2) and the model was significant in interaction between all variables (98% and p < 0.0001, respectively). In addition, the lack of fit test for the model was not of significance, with p > 0.0684. The ethanol concentration, temperature, and ultrasound irradiation time that yielded the maximum value of the total flavonoid content (TFC; 7.47 mg RE/g dried weight (DW)) was 80%, 55 °C, and 45 min, respectively. The optimum value from the validation of the experimental TFC was 7.23 ± 0.15 mg of rutin, equivalent per gram of extract with ethanol concentration, temperature, and ultrasound irradiation time values of 74.20%, 49.99 °C, and 42.82 min, respectively. While the modelled equation fits the data, the T-test is not significant, suggesting that the experimental values agree with those predicted by the response surface methodology models.

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