A review on synthesis methods of tricyclic 1,2,3,4-tetrahydrocarbazoles

In this review article, we discussed old to new synthetic methods used for the preparation of 1,2,3,4-Tetrahydrocarbazole (THCz) based on reported literature. Around the worldwide, various researchers energetically reported new synthetic methods for tetrahydrocarbazoles preparation using conventional method or microwave method or use of catalyst. This review will be helpful to synthetic and medicinal chemist to find selective method for the preparation of 1,2,3,4-Tetrahydrocarbazoles with good percentage yield and less time. This review will also useful to medicinal chemist to design new biologically active tetrahydrocarbazoles based on reported synthetic methods.

Deteksi Kematangan Buah Jambu Kristal Berdasarkan Fitur Warna Menggunakan Metode Transformasi Ruang Warna Hsv (Hue Saturation Value) Dan K-Nearest Neighbor

Guava has properties that are easily damaged, improper handling of guava fruit can result in a decrease in quality and quality. In general, to measure maturity is still done manually, the weakness of this method is the level of accuracy that is not consistent and tends to experience errors. Utilization of images is very important to determine the maturity of guava fruit by utilizing digital images. With the existence of digital images, to determine the maturity of guava fruit based on its color, it can be done computing (technology-based), namely by applying image processing using the HSV (Hue, Saturation, Value) color space transformation method. The HSV (Hue, Saturation, Value) color model groups the intensity components of the carried color information (hue and saturation) in image colors. The results of the ripeness detection can be seen in each test with a percentage value of 91.67% for the ripe guava category, 90% for the raw guava fruit category. The percentage value for testing the overall data has a good percentage value which is influential in detecting the maturity of crystal guava, which is 95%. So it can be concluded that the detection of ripeness of crystal guava fruit can be done by applying the HSV color space transformation method.

Traditional “Congklak” Games and Cooperative Character in Mathematics Larning

Mathematics is one material that most students do not like. In addition to being less attractive, elementary school students also tend to have grades among their peers. This shows the lack of attention applied in learning mathematics. This study aimed to analyze the relationship and influence of cooperative characters with student responses by using traditional games in learning. This type of research uses quantitative methods with the type of comparative research. This research was conducted by distributing questionnaires. The data analysis technique used is random sampling. The research subjects in this study were 120 students. The results obtained are that the cooperative character in the traditional game of Congklak is superior, which is in a very good percentage (60%). The student's response to the traditional game of congklak was very good (55%). The results of the correlation test of the cooperative character of students in traditional games, namely, there is a relationship between the character of cooperation with students' responses to the traditional game of congklak in mathematics. It can be said that there is a relationship and influence of the character of cooperation with student responses. The implication of this research is that playing traditional games in learning can increase students' interest in learning mathematics.

Kinerja Sumber Daya Manusia di Rumah Potong Hewan (Studi Kasus RPH Kategori I dan Kategori II)

This study aims to identify the characteristics of human resources in slaughterhouses category I andcategory II, as well as to analyze the performance and efficiency of human resources in slaughterhousescategory I and category II. Location samples and respondents were determined purposively. Thevariables observed were the characteristics of my human source, my human source performance, andthe efficiency of my human source performance in category I and category II slaughterhouses. Theresults showed that the characteristics of category I and category II employees had an average highschool education, 30-40 years of age and 10-20 years of work. The performance of my human resources(work results, skills, discipline and responsibility) of each slaughterhouse has a fairly good percentage,slaughterhouse for category I (77.66-80.95%) and slaughterhouse for category II (81.68-83.59%) . Theperformance efficiency figures for the employees of the slaughterhouse category I and category II aresimilarly close to number 1 indicating that the employees’ working time is used efficiently.

Evaluation of RNA extraction free method for detection of SARS-COV-2 in salivary samples for mass screening for COVID-19

In this current COVID - 19 pandemic, there is a dire need for cost effective and less time-consuming alternatives for SARS-COV-2 testing. The RNA extraction free method for detecting SARS-COV-2 in saliva is a promising option, this study found that it has high sensitivity (85.34%), specificity (95.04%) and was comparable to the gold standard nasopharyngeal swab. The method showed good percentage of agreement (kappa coefficient) 0.797 between salivary and NPS samples. However, there are variations in the sensitivity and specificity based on the RT-PCR kit used. The Thermo Fischer-Applied biosystems showed high sensitivity, PPV and NPV but also showed higher percentage of invalid reports. Whereas the BGI kit showed high specificity, better agreement (kappa coefficient) between the results of saliva and NPS samples and higher correlation between the Ct values of saliva and NPS samples. Thus, the RNA extraction free method for salivary sample serves as an effective alternative for SARS-CoV 2-testing.

Chemical composition of commercial cuts of pirarucu (Arapaima gigas) processed in different weight classes in the Western Amazon The tropical fish are a food source rich in nutrients, including proteins of high biological value. The fish is present in s

The tropical fish are a food source rich in nutrients, including proteins of high biological value. The fish is present in society's eating habits due to its numerous benefits. Therefore, it is important to know the nutritional components present in the musculature of the fish, this will promote its commercialization and reach more demanding markets, in addition to promoting public health and well-being through its regular consumption. The aimed of this study was to evaluate the chemical composition of commercial cuts of pirarucu (Arapaima gigas) processed in different weight classes. The sample collections were carried out in fish processing units in the state of Rondônia, Brazil. The data were obtained from 77 fish in five weight classes and their commercial cuts evaluated for chemical composition. The Kruskal-Wallis test (α=0.05) was used to compare the averages. The crude protein content of filet mignon increased (p<0.05) with increasing weight. However, the highest lipid content, 6.04%, was in Class 3. The tail filet showed no difference (p>0.05) between the weight classes for mineral content and total lipids. The total lipid levels did not vary between weight classes (p>0.05). The moisture content decreased with increasing body weight. Among the weight ranges with good commercialization, class 4 stands out (14.1 to 18 kg). Among the weight ranges with good commercialization, class 4 (14.1 to 18 kg) stands out, since it presented satisfactory values ​​of proteins and lipids and a good percentage of mineral matter. In other words, it was the most efficient category for production and marketing.

The Influence of Promotion Intensity toward the Increasing of Rice Selling at Sulselbar Regional Division of Bulog Company In Makassar

Promotion Intensity Influence Toward The Increasing Of Rice Selling At Sulselbar Regional Division Of Bulog Company In Makassar. This research was conducted to know the promotion intensity influence toward the increasing of rice selling. Independent variable in this research was the promotion intensity and dependent variable was the increasing of rice selling at Sulselbar Regional Division of Bulog Company in Makassar. The sample in this study was Bulog partner, namely Sahabat RPK (Rumah Pangan Kita) or Our Home Food. Total number of the partners was 152 people and all of them applied Slovin sample theory. Data analysis in this research used SPSS 25 and for technique analysis, the researcher chose reliability test, validity test, classical assumption test, and inferential statistical analysis.The result of this research showed that in promotion intensity variable (X) indicated a very good trend for each indicator. Furthermore, the sales variable (y) showed a very good percentage and there was a significant influence between the intensity of promotion on the increasing of rice selling. It was proven by the result of coefficient analysis with a significance value of 0.000 < 0.05 and also the coefficient of determination (R2) 0.504 or 50.4 percent which indicated that the coefficient of determination model was good and has a positive correlation.

Developing cultural – based English textbook based on total physical response method for elementary school students

This study aimed to develop and provide an enjoyable, meaningful, and cultural – based English textbook for elementary school students on the coast of Kurau village, Bangka Belitung Province. The observation and interview were undertaken to acknowledge the needs of the students in improving and advancing their understanding of English as well as to afford them an expedient textbook to be explored. Lee and Owens (2004) model has been used for this research and development study in designing the book. Total physical response method was also implemented in some exercises within the book to engage students’ attention and comprehension towards English learning. The data gathered in this study were collected through questionnaires, pre-test, and post-test. Based on the data analysis, the research finding shows that the cultural-based English textbook for elementary students is feasible. Feasibility obtained from the book was very good. Percentage of assessment by the content expert reached 82 % and the media expert was 87%. The calculation of T-paired test showed that there was a difference in learning achievement between the pre-test and the post-test score, which was 70.00 to 78.00 or increased 15%. Thus, there is an increasing score and this cultural – based textbook is effective to be used by the elementary students.

Proximal composition, caloric value and price-nutrients correlation of comercial cuts of tambaqui (Colossoma macropomum) and pirarucu (Arapaima gigas) in diferente body weight classes (Amazon: Brazil)

The aimed of the study was to evaluate the caloric value as a function of the proximal composition and correlate the selling price with the nutritional values ​​of commercial cuts of tambaqui (Colossoma macropomum) and pirarucu (Arapaima gigas) in different weight classes. The sample collections were performed in two processing units located in the state of Rondônia, Brazil. Were 200 tambaquis in five weight classes were studied. And, were 77 pirarucus were studied in seven weight classes. The design was completely randomized, with processing carried out in triplicate. The Kruskal-Wallis test (α=0.05) was used to compare the averages and the Spearman correlation (ρ) between price and nutrients. The commercial cuts with the highest caloric value were the tambaqui filet (145.70 kcal/100g) and the pirarucu filet mignon (119.11 kcal/100g) (p<0.05). And the less caloric commercial cuts were steak of tambaqui (100.47 kcal/100g) and pirarucu loin 102.01 kcal/100g) (p<0.05). It was also observed that the variables caloric value and protein content did not correlate with the price of the kilo of fish for the different commercial cuts, which leads to infer that, possibly, the sensorial, market and cultural factors were responsible for the price variations. Regarding the caloric value according to the composition of the tambaqui, the Class 4 was the most efficient category for production and commercialization. And in the composition of the pirarucu, the Class 4 presented satisfactory values of proteins and lipids and a good percentage of mineral matter.

Standards for achieving a comfortable design for the Alzheimer's patients pathways

The elderly is an essential part of society because of their interaction with their surrounding environment and their personal experiences. They were categorized into several levels based on the physiological and psychological needs. Alzheimer's patients constitute a good percentage within society, but there is no accurate data. In cases where the patient suffers from a progressive lack of spatial awareness, studies have developed several criteria to study semi-open spaces intended for the elderly. However, it did not set design standards. Consequently, this paper examines the design standards and requirements for Alzheimer's patients. It is a virtual practical study that simulates optimal standards.