Spontaneous Subarachnoid Haemorrhage in Neurological Setting in Burkina Faso: Clinical Profile, Causes, and Mortality Risk Factors

To determine the prevalence, clinical profile, causes, and mortality risk factors of spontaneous arachnoid haemorrhage at Yalgado Ouedraogo University teaching Hospital, we conducted a 5-year retrospective study of 1803 stroke patients admitted to Neurology Department during the period from January 2012 to December 2016. During the study period, spontaneous subarachnoid haemorrhage accounted for 3.2 % of all stroke. The mean age of patients was 60 years (range 20-93 years). There was a female predominance in 55.9%. The common vascular risk factors were hypertension (79.7%) and chronic alcohol consumption (16.9%). The main symptoms were headache (76.2%), motor weakness (74.5%), and consciousness disorders (62.7%). Neurological examination revealed limb weakness in 76.2% and meningeal irritation in 47.4%. The best admission Glasgow Coma Scale score of 15 was found only in 37.3 % of patients. About 50.8% of patients were admitted to Hunt and Hess moderate grade (III) resulting in a mortality of 24.80%. The main cause of spontaneous subarachnoid haemorrhage was hypertension (77.9%). Cause could not be determined in 8.5 % of cases. The mortality rate was 37.3%. There was high mortality in patients with intraventricular haemorrhage and in patients with disturbances of consciousness. In conclusion, our study showed a poor frequency of spontaneous subarachnoid haemorrhage with high mortality. Hypertension was the most common cause of spontaneous subarachnoid haemorrhage.

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On the Analysis of Mortality Risk Factors for Hospitalized COVID-19 Patients: a Data-driven Study Using the Major Brazilian Database

10.1101/2020.09.24.20200766 ◽

2020 ◽

Author(s):

Fernanda Sumika Hojo Souza ◽

Natália Satchiko Hojo-Souza ◽

Ben Dêivide de Oliveira Batista ◽

Cristiano Maciel da Silva ◽

Daniel Ludovico Guidoni

Keyword(s):

Risk Factors ◽

Heart Disease ◽

Mortality Rate ◽

High Mortality ◽

Mortality Risk ◽

Invasive Mechanical Ventilation ◽

Admission Rate ◽

Older Age ◽

Data Driven ◽

Disease Outcome

Background: Brazil became the epicenter of the COVID-19 epidemic in a brief period of a few months after the first officially registered case. The knowledge of the epidemiological/clinical profile and the risk factors of Brazilian COVID-19 patients can assist in the decision making of physicians in the implementation of early and most appropriate measures for poor prognosis patients. However, these reports are missing. Here we present a comprehensive study that addresses this demand. Methods: This data-driven study was based on the Brazilian Ministry of Health Database (SIVEP-Gripe, 2020) regarding notified cases of hospitalized COVID-19 patients during the period from February 26 to August 10, 2020. Demographic data, clinical symptoms, comorbidities and other additional information of patients were analyzed. Results: The hospitalization rate was higher for male gender (56.56%) and for older age patients of both sexes. Overall, the mortality rate was quite high (41.28%) among hospitalized patients, especially those over 60 years of age. Most prevalent symptoms were cough, dyspnoea, fever, low oxygen saturation and respiratory distress. Heart disease, diabetes, obesity, kidney disease, neurological disease, and pneumopathy were the most prevalent comorbidities. A high prevalence of hospitalized COVID-19 patients with heart disease (65.7%) and diabetes (53.55%) and with a high mortality rate of around 50% was observed. The ICU admission rate was 39.37% and of these 62.4% died. 24.4% of patients required invasive mechanical ventilation (IMV), with high mortality among them (82.98%). The main mortality risk predictors were older age and IMV requirement. In addition, socioeconomic conditions have been shown to significantly influence the disease outcome, regardless of age and comorbidities. Conclusion: Our study provides a comprehensive overview of the hospitalized Brazilian COVID-19 patients profile and the mortality risk factors. The analysis also evidenced that the disease outcome is influenced by multiple factors, as unequally affects different segments of population.

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Pacific islands which escaped the 1918–1919 influenza pandemic and their subsequent mortality experiences

Epidemiology and Infection ◽

10.1017/s0950268812000866 ◽

2012 ◽

Vol 141 (2) ◽

pp. 353-356 ◽

Cited By ~ 9

Author(s):

G. D. SHANKS ◽

J. F. BRUNDAGE

Keyword(s):

Risk Factors ◽

High Mortality ◽

Mortality Risk ◽

Pacific Islands ◽

New Caledonia ◽

Influenza Pandemic ◽

American Samoa ◽

Dichotomous Outcomes

SUMMARYVery few Pacific islands escaped the 1918–1919 influenza pandemic. Subsequent influenza epidemics in the established colonial outposts of American Samoa and New Caledonia infected many but killed very few persons whereas the extraordinarily isolated Niue, Rotuma, Jaliut and Yule islands experienced high mortality influenza epidemics (>3% of population) following 1918. These dichotomous outcomes indicate that previous influenza exposure and degree of epidemiological isolation were important mortality risk factors during influenza epidemics on Pacific islands.

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Epidemiology, Prognosis, and Evolution of Management of Septic Shock in a French Intensive Care Unit: A Five Years Survey

Critical Care Research and Practice ◽

10.1155/2010/436427 ◽

2010 ◽

Vol 2010 ◽

pp. 1-7 ◽

Cited By ~ 3

Author(s):

Nicolas Boussekey ◽

Juliette Cantrel ◽

Lise Dorchin Debrabant ◽

Joachim Langlois ◽

Patick Devos ◽

...

Keyword(s):

Risk Factors ◽

Intensive Care Unit ◽

Septic Shock ◽

Mechanical Ventilation ◽

Intensive Care ◽

High Mortality ◽

Mortality Risk ◽

Simplify Acute Physiology Score ◽

Chronic Alcoholism ◽

New Approach

Purpose. To evaluate the epidemiology, prognosis, and management of septic shock patients hospitalized in our intensive care unit (ICU).Materiel and Methods. Five-year monocenter observational study including 320 patients.Results. ICU mortality was 54.4%. Independent mortality risk factors were mechanical ventilation (), Simplify Acute Physiology Score (SAPS) II > 60 (), chronic alcoholism (), age >65 years (), prothrombin ratio <40% (), and ratio <150 (). These six mortality risk factors recovered allow screening immediately septic shock patients with a high mortality risk. Morbidity improved with time (diminution of septic shock complications, increase of the number of days alive free from mechanical ventilation and vasopressors on day 28), concomitant to an evolution of the management (earlier institution of all replacement and medical therapies and more initial volume expansion). There was no difference in mortality.Conclusion. Our study confirms a high mortality rate in septic shock patients despite a new approach of treatment.

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Frequency and Mortality Risk Factors of Acute Ischemic Stroke in Emergency Department in Burkina Faso

Stroke Research and Treatment ◽

10.1155/2020/9745206 ◽

2020 ◽

Vol 2020 ◽

pp. 1-7

Author(s):

Alfred Anselme Dabilgou ◽

Alassane Dravé ◽

Julie Marie Adeline Kyelem ◽

Saïdou Ouedraogo ◽

Christian Napon ◽

...

Keyword(s):

Risk Factors ◽

Emergency Department ◽

Ischemic Stroke ◽

Mortality Rate ◽

Acute Ischemic Stroke ◽

Mortality Risk ◽

Average Length ◽

University Teaching ◽

Vascular Risk ◽

The Mean

Objective. To determine the prevalence of ischemic stroke deaths and their predictive factors in the Emergency Department at Yalgado Ouedraogo University Teaching Hospital (YOUTH). Methodology. This was a retrospective study with an analytical and descriptive focus over a period of three years from January 1, 2015, to December 31, 2017. Results. During the study period, 302 acute ischemic stroke patients with a mean age of 62.2±14.26 years were included. Atrial hypertension was the most common vascular risk factor in 52.5%. On admission, 34.8% of patients had loss of consciousness. The mean time to perform brain CT was 1.5 days. The average length of stay was 4 days. Electrocardiogram, echocardiography, and cervical Doppler were not performed during hospitalization in ED. The mortality rate was 39%, respectively, 37.6% in male and 41.6% in female. The mean age of patients who died in ED was 63.6±13.52 years. Hypertension was the most common vascular risk factors in 54.2% of death. After logistic regression, the predictors of death were past history of heart disease, consciousness disorders, hyperthermia, hyperglycemia on admission, poststroke pneumonia, and urinary tract infection. Conclusions. Acute ischemic stroke was frequent in Emergency Department with high mortality rate. The mortality risk factors were the same than those found in literature. This higher mortality can be avoided by early diagnosis and an adequate management.

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EARLY PROGNOSIS OF SUBARACHINOID HAEMORRHAGE

Acta Medica Saliniana ◽

10.5457/ams.v37i2.16 ◽

2008 ◽

Vol 37 (2) ◽

pp. 162-165

Author(s):

Mirjana Vidovic ◽

Dzevdet Smajlovic ◽

Osman Sinanovic

Keyword(s):

Risk Factors ◽

Computed Tomography ◽

Subarachnoid Haemorrhage ◽

High Mortality ◽

Clinical Picture ◽

Poor Prognosis ◽

Heart Diseases ◽

Older Age ◽

Subarachnoidal Haemorrhage

Introduction: Subarachnoid haemorrhage presents urgent state in neurology, with dramatic clinical picture and high mortality. Aim of this study was to analize role of the risk factors in prognosis of patients with spontaneous subarachnoidal haemorrhage. Patients and Methods: It was analyzed 48 patients with spontaneous subarachnoidal haemorrhage which are cured on Neurological clinic in Tuzla in period from January 1. 2001 till December 31. 2002. Mean age of patients was 57.6 +/-12. years. Results: It was shown that the most frequent risk factors were hypertension (72.9%), heart diseases (54.1%) and smoking (39.6%). From all 48, 21 (43.7%) patients died. At survived patients, one month from begining of disease, cases. Survived had significant lower mean age (p= .009) and Hunt Hess score (p=0.001) at admission than the died. Patients with complexity find by computed tomography had bad prognosis. Conclusion: Older age of patients, higher number of risk factors, higher Hunt Hess score at admission, and blood in the ventricular system on CT are risk factors for poor prognosis of patients with subarachnoidal haemorrhage.

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Inflammation in Peritoneal Dialysis: A Latin-American Perspective

Peritoneal Dialysis International ◽

10.1177/089686080702700326 ◽

2007 ◽

Vol 27 (3) ◽

pp. 347-352 ◽

Cited By ~ 9

Author(s):

Alfonso M. Cueto-Manzano ◽

Liliana González-Espinoza ◽

Fabiola Martin del Campo ◽

Paulo C. Fortes ◽

Roberto Pecoits-Filho

Keyword(s):

Risk Factors ◽

Latin America ◽

Peritoneal Dialysis ◽

Latin American ◽

High Mortality ◽

Mortality Risk ◽

Adult Population ◽

High Energy ◽

Increased Risk ◽

Sanitary Conditions

Peritoneal dialysis (PD) patients present an extremely high mortality rate, but the mechanisms mediating the increased risk of mortality observed in this group of patients are still largely unknown, which limits the perspective of effective therapeutic strategies. The leading hypothesis that tries to explain this high mortality risk is that PD patients are exposed to a number of traditional risk factors for cardiovascular disease (CVD) already at the onset of their chronic kidney disease (CKD), since many of these risk factors are common to both CVD and CKD. Of particular importance, chronic inflammation recently emerged as an important novel risk factor related to multiple complications of CKD. There are many stimuli of the inflammatory response in CKD patients, such as fluid overload, decreased cytokine clearance, presence of uremia-modified proteins, presence of chronic infections, metabolic disturbances (including hyperglycemia), obesity. Many of these factors are related to PD. Latin America has made some progress in economic issues; however, a large portion of the population is still living in poverty, in poor sanitary conditions, and with many health-related issues, such as an increasing elderly population, low birth weights, and increasingly high energy intake in the adult population, which, in combination with changes in lifestyle, has provoked an increase in the prevalence of obesity, diabetes, and CVD. Therefore, in Latin America, there seems to be a peculiar situation combining high prevalence of low education level, poor sanitary conditions, and poverty with increases in obesity, diabetes, and sedentary lifestyle. Since inflammation and mortality risk are intimately related to both sides of those health issues, in this review we aim to analyze the peculiarities of inflammation and mortality risk in the Latin-American PD population.

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Faculty Opinions recommendation of Mortality risk factors in chronic haemodialysis patients with infective endocarditis.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.13715.471210 ◽

2006 ◽

Author(s):

Ralph Corey

Keyword(s):

Risk Factors ◽

Infective Endocarditis ◽

Mortality Risk ◽

Chronic Haemodialysis

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Analysis of Stress Factors for Female Professors at Online Universities

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph17082958 ◽

2020 ◽

Vol 17 (8) ◽

pp. 2958 ◽

Cited By ~ 1

Author(s):

Marialuz Arántzazu García-González ◽

Fermín Torrano ◽

Guillermo García-González

Keyword(s):

Risk Factors ◽

Time Pressure ◽

Health And Safety ◽

Stress Factors ◽

University Teaching ◽

Psychosocial Risks ◽

Primary Stress ◽

Information And Communication ◽

The University ◽

Mental Overload

The aim of this paper is to analyze the primary stress factors female professors at online universities are exposed to. The technique used for the prospective and exploratory analysis was the Delphi method. Two rounds of consultations were done with fourteen judges with broad experience in health and safety at work and university teaching who reached a consensus of opinion regarding a list of nine psychosocial risk factors. Among the most important risk factors, mental overload, time pressure, the lack of a schedule, and emotional exhaustion were highlighted. These risk factors are related to the usage and expansion of information and communication technology (ICT) and to the university system itself, which requires initiating more research in the future in order to develop the intervention programs needed to fortify the health of the affected teachers and protect them from stress and other psychosocial risks.

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