scholarly journals Plaque Length Predicts the Incidence of Microembolic Signals in Acute Anterior Circulation Stroke

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Liming Zhao ◽  
Hongqin Zhao ◽  
Yicheng Xu ◽  
Aijuan Zhang ◽  
Jiatang Zhang ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Carotid Artery Stenosis ◽  
Carotid Plaque ◽  
Intima Media Thickness ◽  
Roc Curves ◽  
Cross Sectional Study ◽  
Artery Stenosis ◽  
Anterior Circulation ◽  
Cross Sectional ◽  
The Relationship

Microembolic signals (MES) of the carotid artery are associated with plaque destabilization and reoccurrence of stroke. Previous studies have focused primarily on the degree of carotid artery stenosis and plaque components, and the relationship between plaque length and microembolic sign has received little attention. We aimed to find the association between carotid plaque length (CPL) and the presence of MES. We conducted a retrospective observational cross-sectional study. A total of 84 acute anterior-circulation ischemic stroke/transient ischemic attack (TIA) patients with carotid artery atherosclerosis were classified into an MES-positive (MES+) group and MES-negative (MES−) group. We measured multiple parameters of carotid plaque size (length, thickness) in each patient and evaluated the relationship between different plaque parameters and occurrence of MES. We found that male, carotid artery stenosis (CAS), CPL, carotid plaque thickness (CPT), and intima-media thickness (IMT) of the carotid artery were each significantly different between two groups (all P < 0.05 ). The multivariate analysis showed CPL (odds ratio (OR), 1.109; 95% CI, 1.044–1.177; P = 0.001 ) to be independently associated with the presence of MES. The areas under the ROC curves (AUCs) for CPL for predicting MES were 0.777 (95% CI, 0.640–0.914; P < 0.001 ). The cutoff value of CPL for predicting MES was 16.7 mm, with a sensitivity of 88.2% and a specificity of 77.6%. We found that CPL was a meaningful independent predictor of MES. Therefore, CPL may be useful for risk stratification of long and nonstenotic plaques in anterior circulation stroke.

scholarly journals Association between Carotid Artery Stenosis and Cognitive Impairment in Stroke Patients: A Cross-Sectional Study

PLoS ONE ◽  
2016 ◽  
Vol 11 (1) ◽  
pp. e0146890 ◽  
Author(s):  
Wei Yue ◽  
Anxin Wang ◽  
Runxiu Zhu ◽  
Zhongrui Yan ◽  
Shouhuan Zheng ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Carotid Artery ◽  
Carotid Artery Stenosis ◽  
Cross Sectional Study ◽  
Artery Stenosis ◽  
Sectional Study ◽  
Stroke Patients ◽  
Cross Sectional

Prevalence of Carotid Artery Stenosis in Southern China: A Retrospective, Cross-Sectional Study

2013 ◽  
Vol 8 (6) ◽  
pp. E31-E32 ◽  
Author(s):  
Xiao-Yue Hu ◽  
Min Zhang ◽  
Da-Ming Wang ◽  
Xiao-Yan Feng ◽  
Xiao-Lei Shen ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Carotid Artery Stenosis ◽  
Southern China ◽  
Cross Sectional Study ◽  
Artery Stenosis ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Association between lipid profiles and presence of carotid plaque

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Yanhua Liu ◽  
Yongjian Zhu ◽  
Wenrui Jia ◽  
Dan Sun ◽  
Li Zhao ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Carotid Plaque ◽  
Plasma Lipid ◽  
Cross Sectional Study ◽  
Lipid Profiles ◽  
Analysis Of Covariance ◽  
Plaque Composition ◽  
Cross Sectional ◽  
The Mean ◽  
The Relationship

AbstractIt is indicated that lipids profiles are associated with carotid plaque and Atherosclerosis. However, studies about the relationship between serum lipid profiles and carotid plaque composition in Chinese Population is limited. We conducted a cross-sectional study among 3,214 participants between January 2015 and December 2017 in China, to investigate the association between various lipid profiles and the prevalence of carotid plaque. Logistic regression model was used to investigate the association between plasma lipid profiles and odds of carotid plaque. Analysis of covariance (ANCOVA) was used to compare the mean plasma lipid profiles among different number and composition of carotid artery plaques. HDL-C, Non-HDL-C levels, TC/HDL-C, LDL-C/HDL-C were significantly associated with the presence of carotid plaque; HDL-C, LDL-C, Non-HDL-C levels, TC/HDL-C, LDL-C/HDL-C were significantly associated with the presence of common carotid artery (CCA) plaque. Compare with participants without carotid plaque, increased level of LDL-C/HDL-C was found in those with echolucent/polytype plaque. Similarly, compared with participants without CCA plaque, increased level of LDL-C/HDL-C was found in those with echolucent plaque. In conclusion, we found that serum HDL-C, Non-HDLc level, TC/HDLc, and LDLc/HDLc were all associated with the prevalence of carotid plaque, and LDL-C/HDL-C differed among different group of carotid plaque composition.

Carotid Artery Stenosis in Diabetic Patients Presenting With Acute Ischemic Stroke

2020 ◽  
Author(s):  
Ahsan Ashfaq
Keyword(s):  
Ischemic Stroke ◽  
Carotid Artery ◽  
Acute Ischemic Stroke ◽  
Carotid Artery Stenosis ◽  
Cross Sectional Study ◽  
Artery Stenosis ◽  
P Value ◽  
Diabetic Patients ◽  
Chi Square ◽  
Cross Sectional

Background: Stroke is the commonest life-threatening neurological disorder. The Abnormal narrowing or stenosis of the Carotid Artery is a major determinant of ischemic stroke in diabetic patients. The main objective of study was to estimate the frequency of carotid artery stenosis in diabetic patients presenting with acute ischemic stroke. Methods: This was a Cross-Sectional study conducted at Medicine wards Jinnah Post-Graduate Medical Centre, Karachi from 5th December 2014 to 5th June 2015. Total 101 patients were included. During the hospitalization, patients were subjected to carotid Doppler ultrasonography to assess carotid artery stenosis. Patients were provided routine medical care during the hospitalization. Data was analyzed using SPSS v23.0. Chi-Square was used to analyze the differences between the categories. The p-value of <0.05 was considered as significance. Results: Total 101 patients were included in the study. There were 71.8% males and 28.2% females. The mean age was 53.7±10.2 years. On analysis of risk factors, it was observed that 59% patients had hypertension, 34.2% patients were obese, 34.2% patients had dyslipidemia, 51.3% patients had history of smoking. On analysis of carotid artery stenosis among the diabetics, it was observed that 20.8% diabetics had carotid artery stenosis. Conclusion: Stenosis of Carotid artery was common in patients suffering from acute ischemic stroke and diabetes mellitus. Among modifiable risk factor in patients with stroke having carotid artery stenosis, Hypertension was most common whereas fasting blood sugar FBS level greater than 100 g/dl lead to increased chances of having carotid artery stenosis.

High-Intensity Signal in Carotid Plaque on Routine 3D-TOF-MRA Is a Risk Factor of Ischemic Stroke

2015 ◽  
Vol 41 (1-2) ◽  
pp. 13-18 ◽  
Author(s):  
Kiyofumi Yamada ◽  
Masanori Kawasaki ◽  
Shinichi Yoshimura ◽  
Manabu Shirakawa ◽  
Kazutaka Uchida ◽  
...  
Keyword(s):  
Risk Factor ◽  
Ischemic Stroke ◽  
Carotid Artery ◽  
Carotid Artery Stenosis ◽  
Carotid Plaque ◽  
Artery Stenosis ◽  
Carotid Plaques ◽  
Tof Mra ◽  
The Relationship ◽  
Ischemic Events

Background: Carotid atherosclerotic disease is recognized as an important risk factor for brain ischemic events. However, high-grade stenosis does not always cause ischemic strokes, whereas moderate-grade stenosis may often cause ischemic strokes. It has been reported that there is an association between carotid intraplaque hemorrhage (IPH) and new cerebral ischemic events. The purpose of this study was to elucidate the relationship between high-intensity signals (HIS) on maximum intensity projection (MIP) images from routine 3-dimensional time-of-flight magnetic resonance angiography (3D-TOF-MRA) and prior ischemic strokes in the patients with moderate carotid stenosis. Materials and Methods: Sixty-one patients with moderate carotid artery stenosis (50-69% stenosis based on North American Symptomatic Carotid Endarterectomy Trial criteria) were included. Carotid IPH was defined as the presence of HIS in carotid plaques on MIP images detected by 3D-TOF-MRA using criteria we previously reported. We analyzed the relationship between the presence of HIS in plaques and prior ischemic strokes defined as ischemic lesions on diffusion-weighted brain images. Results: HIS in carotid plaques were present in 27 (44%) of 61 patients. Prior ipsilateral ischemic strokes occurred more frequently in the HIS-positive group than the HIS-negative group (67 vs. 9%, p < 0.001). Furthermore, there were more smokers in the group with ischemic stroke than without it (62 vs. 25%, p = 0.005). In multivariate logistic regression analysis, HIS in carotid plaque (OR 23.4, 95% CI 4.62-118.3, p < 0.001) and smoking (OR 5.44, 95% CI 1.20-24.6, p = 0.028) were independent determinants of prior ischemic strokes after adjustment for age. Conclusions: HIS in carotid plaques on 3D-TOF-MRA MIP images are independent determinants of prior ischemic strokes in patients with moderate carotid artery stenosis, and they can potentially provide a reliable risk stratification of patients with moderate carotid artery stenosis.

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